List of omics@vib project topics
For the current omics@VIB call, VIB provides 10 positions for integrative biology postdocs. Many VIB laboratories are suggesting an integrative biology topic for this program as indicated in the list below. You are free to select the topic of your own choice from the list and to design a 3 years postdoctoral project addressing this topic. More information on the laboratory of your choice as well as on the contact information is available through the links provided below. Please contact the group leader(s) in charge of this topic before submitting your final application.
· Cancer
· Cardiovascular
· Neurobiology
· Immunity/Infection/Inflammation
· Plant/Yeast research
· Bioinformatics/Proteomics
Cancer
Peter Carmeliet Lab
Unbiased, genome wide-micro RNA profiling in endothelial cells to identify novel genetic candidates for anti-angiogenic therapy
> See also 'Cardiovascular'
e-mail
Max Mazzone Lab
PHD oxygen sensors and cancer: unraveling new hubs in the hypoxia response
e-mail
SWITCH Lab
Mapping aggregation interactomes in human conformational diseases
> See also 'Bioinformatics'/ 'Proteomics'; 'Neurobiology'
e-mail / e-mail
Frans Van Roy Lab
Metazoan cadherin and catenin superfamilies: evolution from ancestral metazoan organisms to mammals, as addressed by bio-informatics, structural and functional analysis
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Chris Marine Lab
An oncogenomics-based in-vivo screen to identify IncRNAs that modulate melanoma progression and metastasis
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Diether Lambrechts Lab
Understanding hypoxia-driven changes in the tumor epigenome through an integrated epigenomic and proteomic approach
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Geert Berx Lab
EMT-drawing a functional genome wide epigenetic landscape for coding and non-coding RNAs that drives malignant cancer progression.
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Jan Cools Lab
Interpretation of leukemia genomes and transcriptomes through integrative regulatory genomics
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Cardiovascular
Jody Haigh Lab
Identification and functional characterization of non-coding RNAs involved in cardiovascular cell (de)differentiation
e-mail
Peter Carmeliet Lab
Unbiased, genome wide-micro RNA profiling in endothelial cells to identify novel genetic candidates for anti-angiogenic therapy
> See also 'Cancer'
e-mail
Neurobiology
Emre Yaksi Lab
Quantitative approaches to study the role of neuromodulation in brain circuits and animal behavior
e-mail
Wim Annaert Lab
Subcellular proteomics/lipidomics as an integrative approach to identify novel targets in neurodegenerative diseases
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Bart De Strooper Lab
Deep-sequencing and bioinformatics analysis of coding and non-coding RNAs in Alzheimer's Disease
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Bassem Hassan Lab
Live quantitative decoding of the transcriptional control of neural identity through in vivo functional genomics.
e-mail
Albena Jordanova Lab
Identification of neurodegenerative pathways triggered by mutations in aminoacyl-tTNA synthetases using functional genomics and transcriptomics approaches in Drosophila
e-mail
Claudia Bagni Lab
Analysis of CYFIP1 transcriptomics: relevance to Autism, FXS and Schizofrenia
e-mail
Patrik Verstreken Lab
Synaptic ubiquitome changes in Parkinson's disease
e-mail
SWITCH Lab
Mapping aggregation interactomes in human conformational diseases
> See also 'Bioinformatics'/ 'Proteomics'; 'Cancer'
e-mail / e-mail
Vincent Bonin Lab
Combining computational, imaging and optogenetic approaches to investigate visual processing in the awake mouse brain
e-mail
Immunity/Infection/Inflammation
Peter Vandenabeele Lab
Global analysis of transcriptome and spliceosome during modulation of necroptosis sensitivity
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Rudi Beyaert Lab
Dissecting inflammation and innate immunity through the 'omics' glass
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Jeroen Raes Lab
Combining multi-omics to investigate host-microbiome interplay towards personalized medicine
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Stefan Magez Lab
Immunomics of chronic infections: mapping a host-parasite immune interactome with the aim of designing a new approach to the currently failing strategies of anti-parasite vaccination
e-mail
Mo Lamkanfi Lab
Exploring the specific Nlrp6 interactome and its role in immune signaling
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Adrian Liston Lab
Functional validation of novel autoimmune genes found through genomic screening
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Claude Libert Lab
State of the art bioinformatics at genome-wide level to identify, validate and model novel genetic factors that determine anti-inflammation therapy with glucocorticoids in several model systems
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Jan Steyaert Lab
Next generation sequencing technologies applied to nanobody discovery: by-passing in vitro screening by phage display for direct in silico candidate selection
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Joris Messens Lab
The interaction proteome of oxidative stress signaling in Mycobacterium tuberculosis
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Patrick Van Dijck Lab
Protein-protein interactions, metabolic flux and methylation status: an integrated study of the role of the methionine biosynthetic pathway during host-pathogen interaction and biofilm formation in the human fungal pathogen Candida albicans
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Plant/Yeast
Lieven De Veylder Lab
Modeling endoreduplication in developing tissues of Arabidopsis thaliana
e-mail
Jenny Russinova Lab
Deciphering the brassinosteroid signaling network in plants by the proteome
e-mail
Geert De Jaeger Lab
Isolation of new cell growth regulators by mapping the protein interactome dynamics at G1 re-entry in Arabidopsis thaliana
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Frank Van Breusegem Lab
Omics-assisted discovery of photorespiratory network components targeted by small molecules
e-mail
Steven Maere Lab
A novel approach to probe crosstalk between plants stress response pathways under field conditions
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Mieke Van Lijsebettens Lab
Identification of the molecular networks of chromatin modifying complexes to investigate their role in leaf growth and plasticity
e-mail
Alain Goossens Lab
Genome-wide monitoring of changes in transcription factor binding and chromatin modification following jasmonate perception in the model plants Arabidopsis and Medicago
e-mail
Wout Boerjan Lab
Genome-wide association genetics of the aromatic metabolome/lignome in Arabidopsis
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Johan Thevelein Lab
Application of whole-genome complex trait analysis to elucidate a novel nutrient signaling pathway in yeast
> See also 'Bioinformatics'/ 'Proteomics'
e-mail
Bioinformatics/Proteomics
Lennart Martens Lab
Building an inverse search engine: learning from integrated across-omics life sciences data which questions can be answered
e-mail
SWITCH Lab
Mapping aggregation interactomes in human conformational diseases
> See also 'Cancer'; 'Neurobiology'
e-mail / e-mail
Steven Maere Lab
A novel approach to probe crosstalk between plants stress response pathways under field conditions
> See also 'Plant/Yeast'
e-mail
Jeroen Raes Lab
Combining multi-omics to investigate host-microbiome interplay towards personalized medicine
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Frans Van Roy Lab
Metazoan cadherin and catenin superfamilies: evolution from ancestral metazoan organisms to mammals, as addressed by bio-informatics, structural and functional analysis
> See also 'Cancer
e-mail
Adrian Liston Lab
Functional validation of novel autoimmune genes found through genomic screening
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Claude Libert Lab
State of the art bioinformatics at genome-wide level to identify, validate and model novel genetic factors that determine anti-inflammation therapy with glucocorticoids in several model systems
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Bart De Strooper Lab
Deep-sequencing and bioinformatics analysis of coding and non-coding RNAs in Alzheimer's Disease
> See also 'Neurobiology'
e-mail
Chris Marine Lab
An oncogenomics-based in-vivo screen to identify IncRNAs that modulate melanoma progression and metastasis
> See also 'Cancer'
e-mail
Diether Lambrechts Lab
Understanding hypoxia-driven changes in the tumor epigenome through an integrated epigenomic and proteomic approach
> See also 'Cancer'
e-mail
Geert Berx Lab
EMT-drawing a functional genome wide epigenetic landscape for coding and non-coding RNAs that drives malignant cancer progression.
> See also 'Cancer'
e-mail
Geert De Jaeger Lab
Isolation of new cell growth regulators by mapping the protein interactome dynamics at G1 re-entry in Arabidopsis thaliana
> See also 'Plant/Yeast'
e-mail
Jan Tavernier Lab
Next-generation human interactome mapping: development and application of a high throughput micro-array MAPPIT technology platform
e-mail
Jan Steyaert Lab
Next generation sequencing technologies applied to nanobody discovery: by-passing in vitro screening by phage display for direct in silico candidate selection
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Joris Messens Lab
The interaction proteome of oxidative stress signaling in Mycobacterium tuberculosis
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Kevin Verstrepen Lab
Hunting for unstable tandem repeats in the human genome: an overlooked source of missing heritability and cryptic diseases
e-mail
Kris Gevaert Lab
In-depth analysis and functional validation of the substrates of the cytosolic metallo-caboxypeptidases using comtemporary degradomics
e-mail
Mo Lamkanfi Lab
Exploring the specific Nlrp6 interactome and its role in immune signaling
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Nico Callewaert Lab
Genome analysis-enabled directed evolution of the glycome of biopharmaceutical cell factories
e-mail
Patrick Van Dijck Lab
Protein-protein interactions, metabolic flux and methylation status: an integrated study of the role of the methionine biosynthetic pathway during host-pathogen interaction and biofilm formation in the human fungal pathogen Candida albicans
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Peter Tompa Lab
Comparative analysis of cellular regulatory and quality control mechanisms integrating functional, structural and interaction data on the ubiquitin-proteasome pathway
e-mail
Peter Vandenabeele Lab
Global analysis of transcriptome and spliceosome during modulation of necroptosis sensitivity
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Rudi Beyaert Lab
Dissecting inflammation and innate immunity through the 'omics' glass
> See also 'Immunity'/ 'Infection' / 'Inflammation'
e-mail
Wim Annaert Lab
Subcellular proteomics/lipidomics as an integrative approach to identify novel targets in neurodegenerative diseases
> See also 'Neurobiology'
e-mail
Wout Boerjan Lab
Genome-wide association genetics of the aromatic metabolome/lignome in Arabidopsis
> See also 'Plant/Yeast'
e-mail