leslie s. prichep
1010 Orienta Avenue
Mamaroneck, New York 10543
212-263-6296
Education
Year / Degree / Field / Institution1968 / B.S. / Physiological Psychology / University of Pittsburgh
1969 / M.S. / Biopsychology / University of Pittsburgh
1974 / Ph.D. / Experimental Psychopathology / City University of New York
Postgraduate Training
1968-1969 Psychobiology Research Traineeship Robert Gibson, Ph.D.
University of Pittsburgh
1969-1970 Bio-Medical Sciences Research Training Fellowship James Orbach, Ph.D.
Queens College, CUNY
1974-1975 Postdoctoral Research Fellowship Psychophysiology Samuel Sutton, Ph.D. NYS Psychiatric Institute
Biometric Research
Certification
2001 EEG, Neurophysiology and QEEG: ECNS, ABEN
Academic Appointments
2005-Present Professor of Psychiatry (Research), NYU School of Medicine, New York
1983-2005 Associate Professor of Psychiatry (Research),NYU School of Medicine, New York
1976-1983 Assistant Professor of Psychiatry (Research), NYU School of Medicine, New York
1970-1974 Adjunct Lecturer, Dept. of Psychology, Queens College of CUNY, New York
Professional Appointments
1988-current Acting Director, Brain Research Laboratories, Dept. of Psychiatry,
New York University School of Medicine, New York
2000-2011 Research Scientist VI, Nathan Kline Institute for Psychiatric Research,
New York State Office of Mental Health, Orangeburg, N.Y
2007-2010 Member Faculty Council, New York University School of Medicine
1986-2000 Research Scientist V, Nathan Kline Institute for Psychiatric Research,
New York State Office of Mental Health, Orangeburg, N.Y
1974-1976 Research Associate and Clinical Liaison, The Brain Research Laboratories,
NY Medical College, New York
1972-1974 Director of Research and Evaluation, Project Outreach, Jewish-Hillside
Medical Center; Glen Oaks, N.Y.
1971-1972 Research Assistant, Department of Psychology, Queens College,
City University of New York, NY
1970-1972 Research Assistant, Department of Research, Jewish-Hillside Medical
Center, Glen Oaks, NY
Awards and Honors
1966 Elected Member Psi Chi, Quax, and Sigma Chi (National Science Honorary Societies)
1968 Cum Laude Graduate, University of Pittsburgh
1975 Dissertation nominated for NY Academy of Sciences James McKeen Cattel Award for outstanding dissertation
1989 Wyeth-Ayerst Award for Distinction in Psychiatry, Conferred at the VIII World Congress of Psychiatry
Memberships, Offices and Committee Assignments in Professional Societies
Member:
American Psychological Association
American Society of Evoked Potential Monitoring
College on Problems of Drug Dependence (CPDD)
International Academy for Research in Learning Disabilities
International Organization of Psychophysiology
International Society for NeuroImaging in Psychiatry
New York Academy of Sciences
Board Member:
International Pharmaco-EEG Society
EEG & Clinical Neuroscience Society
Committee Task Force Assignments:
1995-2004 Special Review Consultant, National Institute on Drug Abuse, Basic
Behavioral Sciences Research Subcommittee
2002-2008 Chair, Ph.D. Certification Committee, EEG and Clinical Neuroscience Society
2008-2010 Chair Non-Tenured Faculty Committee of Faculty Council NYUSOM
2012 Member NINDS TBI CDEs - Concussion/Mild TBI Task Force
Editorial Positions
Editorships:
Clinical EEG
Ad Hoc Reviewer for:
Alzheimer's Disease and Associated Disorders
Behavioral Neuroscience
Biological Psychiatry
Clinical Neurophysiology
Journal of Alzheimer’s Disease
Neurobiology of Aging
NeuroImage
Psychiatry Research: Neuroimaging
Major Administrative Responsibilities
1988- Acting Director for Brain Research Laboratories, Dept. of Psychiatry,
NYU School of Medicine
1995-2008 Director, Neurometric Evaluation Service, Brain Research Laboratories,
Dept. of Psychiatry, NYU School of Medicine
2003-2007 Chair, Phoenix House Foundation Institution Review Board (IRB)
Patents:
[1] Use of Brain Electrophysiological Quantitative Data to Classify and Subtype an Individual into Diagnostic Categories by Discriminant and Cluster Analysis:
Inventor: L.S. Prichep [#5,083,571] Issued 1/28/1992
Assignee: NYUSOM
[2] Fetal Brain Monitor: [#9,716,517] Issued 11/13/2001
Inventor: L.S. Prichep
Assignee: NYUSOM
[3] System and method for Guidance of Anesthesia, Analgesia and Amnesia
Inventors: E.R. John & L.S. Prichep Issued 8/15/2006
Assignee: NYUSOM [#7,089,927]
[4] System and Method for Prediction of Cognitive Decline
Inventor: L.S. Prichep Issue Date: 8/26/2009
Assignee: NYUSOM
[5] System and Method for Pain Detection and Computation of a Pain Quantification Index
Inventor: E.R. John, L.S. Prichep, E. Hiesiger Issue Date: Pending [2009]
Assignee: NYUSOM
Publications
Peer Reviewed Articles, Books and Book Chapters
Prichep LS, McCrea M, Barr W, Powell M, Chabot R J. Time Course of Clinical and Electrophysiological Recovery After Sport-Related Concussion. Journal of Head Trauma and Rehabilitation. 2013; epub ahead of print doi: 10.1097/HTR.0b013e318247b54e.
Prichep LS, Jacquin A, Filipenko J, Ghosh Dastidar S, Zabele S, Vodencarevic A, Rothman NS. Classification of traumatic brain injury severity using informed data reduction in a series of binary classification algorithms. IEEE Transactions on Neural Systems and Rehabilitation
Engineering. 2012; 20; 806-822.
Prichep LS, John ER, Howard B, Merkin H, Hiesiger E. Assessment of pain using Quantitative EEG source imaging. Pain Medicine. 2011; 12: 1241-48.
Prichep LS. Quantitative EEG and Electromagnetic Brain Imaging in Aging and in the Evolution ofDementia. Ann.N.Y.Acad Sci. 2007; 40: 1-12.
Prichep LS, John ER, Ferris SH, Rausch L, Fang Z, Rausch L, Cancro R, Torrossian C, Reisberg B. Prediction of longitudinal cognitive decline in normal elderly with subjective complaints using electrophysiological imaging. Neuro Biol Aging 2006; 27: 471-81.
Prichep LS, Causevic E, Coifman RR, Isenhart R, Jacquin A, John ER, Maggioni M, Warner FJ. QEEG-based classification with wavelet packet and microstate features for triage applications in ER. ICASSP 2006; 3:1136-9.
Prichep LS. Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: Importance and cautions. Clinical EEG 2005; 36: 82-7.
Prichep LS, Gugino LD, John ER, Chabot RJ, Howard B, Merkin HA, Tom M, Wolter S, Rausch L, Kox W. The Patient State Index (PSI) as an indicator of the level of hypnosis under general anesthesia. British Journal of Anaesthesia 2004; 92: 393-9.
Prichep LS, Alper KR, Sverdlov L, Kowalik SC, John ER, Merkin HTM, Howard B, Rosenthal MS. Outcome related electrophysiological subtypes of cocaine dependence. Clinical EEG 2002; 33: 8-20.
Prichep LS, John ER, Tom M. Localization of deep white matter lymphoma using VARETA - A case study. Clinical EEG 2001; 32: 62-6.
Prichep LS, John ER, Gugino LD, Kox W, Chabot R. Quantitative EEG assessment of changes in the level of the sedation/hypnosis during surgery under general anesthesia: I. The Patient State Index (PSI). In: Jordan C, Vaughan DJA, Newton DEF, eds. Memory and Awareness in Anesthesia. IV edn. London: Imperial College Press; 2000: 97-102.
Prichep LS, Alper KR, Kowalik SC, Vaysblat L, Merkin HA, Tom M, John ER, Rosenthal MS. Prediction of treatment outcome in cocaine dependent males using quantitative EEG. Drug Alc.Depend. 1999; 54: 35-43.
Prichep LS, John ER, Chabot RJ, Gugino LD, Kox W. PSI Prediction of "arousal" events during surgery under continuous intravenous, inhalation or nitrous/narcotic anesthesia. Memory and Awareness in Anesthesia. Harrow: 1998.
Prichep LS, Alper K, Kowalik SC, Rosenthal MS. Neurometric QEEG studies of crack cocaine dependence and treatment outcome. J. Addictive Diseases 1996; 15: 39-53.
Prichep LS, Alper K, Kowalik SC, John ER, Merkin HA, Tom M, Rosenthal MS. Quantitative electroencephalographic characteristics of crack cocaine dependence. Biol.Psychiat. 1996; 40: 986-93.
Prichep LS, Kowalik SC, Alper KR, DeJesus C. Quantitative EEG characteristics of children exposed in utero to crack cocaine. Clinical EEG 1995; 26: 166-72.
Prichep LS, John ER, Ferris SH, Reisberg B, Alper KR, Cancro R. Quantitative EEG correlates of cognitive deterioration in the elderly. Neurobiology Aging 1994; 15: 85-90.
Prichep LS, Mas F, Hollander E, Liebowitz M, John ER, Almas M, DeCaria CM, Levine RH. Quantitative electroencephalographic subtyping of obsessive-compulsive disorder. Psychiatry Res. 1993; 50 : 25-32.
Prichep LS, John ER. QEEG profiles of psychiatric disorders. Brain Topography. 1992; 4: 249-257
Prichep LS, John ER, Easton P, Chabot R. Cross-spectral coherence at rest and during mental activity. In: John ER, ed. Machinery of the Mind. Boston: Birkhauser; 1990: 471-8.
Prichep LS, John ER, Essig-Peppard T, Alper KR. Neurometric subtyping of depressive disorders. In: Cazzullo CL, Invernizzi G, Sacchetti E, Vita A, eds. Plasticity and Morphology of the CNS. London: M.T.P. Press; 1990.
Prichep LS, Mas F, John ER, Levine R. Neurometric subtyping of obsessive compulsive disorders. In: Stefanis CN, Rabavilas AD, Soldatos CR, eds. Psychiatry: A World Perspective. Amsterdam: Elsevier; 1990: 557-62.
Prichep LS, John ER, Mas F, Essig-Peppard T. Subtyping of Schizophrenia. In: John ER, ed. Machinery of the Mind. Birkhauser; 1990: 460-70.
Prichep LS. Neurometric QEEG measures of depressive disorders. In: Takahashi P, Flor-Henry J, eds. Cerebral Dynamics, Laterality and Psychopathology. Amsterdam: Elsevier; 1987: 55-69.
Prichep LS, John ER, Alper K, Gomez-Mont F, Essig-Peppard T, Flitter M. Quantitative EEG in depressive disorders. In: Shagass C, Josiassen RC, and Roemer RA, eds. Brain Electrical Potentials and Psychopathology. Amsterdam: Elsevier; 1986: 223-44.
Prichep LS, John ER. Neurometrics: Clinical Applications. In: Lopes Da Silva F, van Leeuwen WS, Remond A, eds. Handbook of Electroencephalography and Clinical Neurophysiology, Vol. 2. Amsterdam: Elsevier; 1986: 153-70.
Prichep LS, John ER, Ransohoff J, Cohen N, Benjamin V, Ahn H. Realtime intraoperative monitoring of cranial nerves VII and VIII during posterior fossa surgery. In: Morocutti C, Rizzo PA, eds. Evoked potentials. Neurophysiological and Clinical Aspects. Elsevier; 1985: 193-202.
Prichep LS, Gomez-Mont F, John ER, Ferris SH. Neurometric Electroencephalographic characteristics of dementia. In: Reisberg B, ed. Alzheimer’s Disease: The Standard Reference. The Free Press (MacMillan); 1983: 252-7.
Prichep LS, Sutton S, Hakerem G. Evoked potentials in hyperkinetic and normal children under certainty and uncertainty. Psychophysiology 1976; 13: 419-28.
Prichep LS, Cohen M, Kaplan J, Kalin E, Klein D. Psychiatric examination of court referred drug users. Am J of Drug and Alcohol Abuse 1975; 2: 197-213.
Hanley DF, Chabot R, Mould WA , Morgan T, Naunheim R, Sheth KN, Chiang W, Prichep LS.
Use of brain electrical activity for the identification of hematomas in mild traumatic brain
injury. Journal of Neurotrauma: In Press
Alper K, Shah J, Howard B, John ER, Prichep LS. Childhood abuse and EEG source
localization in crack cocaine dependence. Psychiatry Research:Neuroimaging. 2013;213:63-70
O'Neil B, Prichep LS, Naunheim RS, Chabot RJ. Can quantitative brain electrical activity aid in the triage of mild traumatic brain injured patients. Western Journal of Emergency Medicine. 2012;13: 394-400.
Barr WB, Prichep LS, Chabot RJ, Powell MR, McCrea M. Measuring brain electrical activity to track recovery from sport related concussion. Brain Inj. 2012; 26: 58-66.
Pascual-Marqui RD, Lehmann D, Koukkou M, Kochi K, Anderer P, Saletu B, Tanaka H, Hirata K, John ER, Prichep LS, Biscay-Lirio R, Kinoshita T. Assessing interactions in the brain with exact low-resolution electromagnetic tomography. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2011; 369: 3768-3784.
John ER, Halper JP, Lowe RS3, Merkin H, DeFina P, Prichep LS. Source Imaging of QEEG as a bedside method to detect awareness in a patient in a vegetative state. Brain Injury 2011; 25[4], 426-432.
McCrea M, Prichep LS, Powell MR, Chabot R, Barr WB. Acute Effects and Recovery After Sport-Related Concussion: A Neurocognitive and Quantitative Brain Electrical Activity Study. The Journal of Head Trauma Rehabilitation 2010;25: 283-292.
Congedo M, John ER, De Ridder D, Prichep LS, Isenhart R. Group independent component analysis of resting-state EEG in large normative samples. International Journal of Psychophysiology 2010; 78(2): 88-99.
Congedo M, John ER, De Ridder D, Prichep LS, Isenhart R. On the "Dependence" of "Independent" Group EEG Sources; an EEG Study on Two Large Databases. Brain Topography 2010; 23(2):134-138.
John ER, Prichep LS. Principles and applications of quantitative electroencephalogram in psychiatry. In: Sadock BJ, Sadock VA, Ruiz P, eds. Kaplan and Sadock's Comprehensive Textbook of Psychiatry. 9th edition. Philadelphia: Lippincott Williams & Wilkins; 2009: 1013-32.
Alper K, Raghavan M, Isenhart R, Howard B, Doyle W, John ER, Prichep LS. Localizing epileptogenic regions in partial epilepsy using three-dimensional statistical parametric maps of background EEG source spectra. Neuroimage 2008; 39: 1257-65.
Reid MS, Flammino F, Howard B, Nilsen D, Prichep LS. Cocaine cue versus cocaine dosing in humans: Evidence for distinct neurophysiological response profiles. Pharmacology Biochemistry and Behavior 2008; 91: 155-64.
Reisberg B, Prichep LS, Mosconi L, John ER, Glodzik-Sobanska L, Boksay I, Monteiro I, Torossian C, Vedvyas A, Ashraf N, Jamil IA, de Leon MJ. The pre-mild cognitive impairment, subjective cognitive impairment stage of Alzheimer's disease. Alzheimer's and Dementia 2008; 4: S98-S108.
Bolwig TG, Hansen ES, Hansen A, Merkin H, Prichep LS. Toward a better understanding of the pathophysiology of OCD SSRI responder: QEEG source localization. Acta Psychiatr Scand 2007; 115: 237-42.
John ER, Prichep LS, Winterer G, Hermann WM, diMichele F, Halper J, Bolwig T, Cancro R. Electrophysiological subtypes of psychotic states. Acta Psychiatrica Scandinavia 2007; 116: 17-35.
Lehmann C, Koenig T, Jelic V, Prichep LS, John ER, Walhlund L, Dodge Y, Dierks T. Application and comparison of classification algorithms for recognition of Alzheimer's disease in electrical brain activity (EEG). Journal of Neuroscience Methods 2007; 161: 342-50.
Alper KA, John ER, Brodie J, Gunther W, Daruwala R, Prichep LS. Correlation of PET and QEEG in normal Subjects. Psychiatry Research: Neuroimaging 2006; 146: 271-82.
John ER, Prichep LS. The Relevance of QEEG to the Evaluation of Behavioral Disorders and Pharmacological Interventions. Clinical EEG and Neuroscience 2006; 37: 135-43.
Kox W, von Heymann C, Heinze J, Prichep LS, John ER, Rundshagen I. Electroencephalographic mapping during routine clinical practice: cortical arousal during tracheal intubation? Anesthesia and Analgesia 2006; 102: 825-31.
Reid MS, Flammino F, Howard B, Nilsen D, Prichep LS. Topographic imaging of Quantitative EEG in response to smoked cocaine self-administration in humans. Neuropsychopharmacology 2006; 31: 872-4.
Chabot RJ, di Michele F, Prichep LS. The role of quantitative electroencephalography in child and adolescent psychiatric disorders. Child and Adolescent Psychiatric Clinics of North America 2005; 14: 21-53.
di Michele F, Prichep LS, John ER, Chabot RJ. The neurophysiology of attention-deficit/hyperactivity disorder. International Journal of Psychophysiology 2005; 58: 81-93.
John ER, Prichep LS. The anesthetic cascade: how anesthesia suppresses awareness. Anesthesiology 2005; 102: 447-71.
Koenig T, Prichep LS, Dierks T, Hubl D, Wahlund LO, John ER, Jelic V. Decreased EEG synchronization in Alzheimer's disease and mild cognitive impairment. Neurobiology of Aging 2005; 26: 165-71.
Rundshagen I, Schroder T, Prichep LS, John ER, Kox WJ. Changes in cortical electrical activity during induction of anaesthesia with thiopental/fentanyl and tracheal intubation. A quantitative electroencephalographic analyses. British J.Anaesth. 2004; 92: 33-8.