Karen K. Miller, M.D.

Curriculum Vitae

Part I: General Information

DATE PREPARED: 2/3/2000

Name:Karen Klahr Miller

Office Address:Neuroendocrine Unit, Bulfinch 457B, Massachusetts General Hospital

Place of Birth:Baltimore, MD

Education:

1982 B.A.Yale College

1987 B.S.Columbia University School of Journalism

1992 M.D.Johns Hopkins University School of Medicine

Postdoctoral Training:

Internships and Residencies:

1992-1993Intern in Medicine, Brigham and Women’s Hospital

1993-1994Junior Resident in Medicine, Brigham and Women’s Hospital

1994-1995Senior Resident in Medicine, Brigham and Women’s Hospital

Clinical and Research Fellowships:

1995-1996Clinical Fellow, Endocrine Unit, Massachusetts General Hospital

1996-1998Research Fellow, Neuroendocrine Unit, Massachusetts General Hospital

Licensure and Certification:

1995American Board of Internal Medicine Certificate

1995Massachusetts License Registration

1998Endocrinology and Metabolism Certification

Academic Appointments:

1995-1998Postdoctoral Research Fellow in Medicine, Harvard Medical School

1998-Instructor in Medicine, Harvard Medical School

Hospital or Affiliated Institution Appointments:

1995-1996Essential Clinical Fellow, Department of Medicine, Massachusetts General Hospital

1996-1998Research Fellow, Department of Medicine, Massachusetts General Hospital

1998-1999Clinical Assistant, Department of Medicine, Massachusetts General Hospital

2000-Assistant in Medicine, Department of Medicine, Massachusetts General Hospital

Professional Societies:

1992-American College of Physicians

1995-American Association of Clinical Endocrinologists

1997-The Endocrine Society

1997-Women in Endocrinology
Professional Societies (Cont’d):

1998-Pituitary Society

Awards and Honors:

1982Summa Cum Laude, Yale College

1982Phi Beta Kappa, Yale College

1982Honors in the Philosophy Major, Yale College

1982Graduation with Honors, Columbia University School of Journalism

1992Alpha Omega Alpha, Johns Hopkins University School of Medicine

1997Recipient, National Research Service Award, National Institutes of Health

1998Recipient, Clinical Research Scholar Award, National Institutes of Health

1998Recipient, Janet McArthur Award, Women in Endocrinology

1998Recipient, Boston Obesity Nutrition Research Center Pilot Research Award

1999Recipient, Clinical Associate Physician Award, National Institutes of Health

1999-2001Claflin Distinguished Scholar

Report of Teaching

Local contributions:

a. Courses

Massachusetts General Hospital

1997-Lecturer, Endocrinology Lecture, Institute of Health Professions.

1998-Lecturer, Neuroendocrine Clinical Conferences, Neuroendocrine Unit, MGH

Harvard Medical School

1996-Section Leader, Introduction to Clinical Medicine

b. Invited presentations:

Massachusetts General Hospital

1995Endocrine Grand Rounds

“Supra-sellar Germinomas”

1995Thyroid/Neuroendocrine Conference

“Thyroid Disease and Reproductive Function”

1996Endocrine Grand Rounds

“Lymphocytic Hypophysitis”

1996Reproductive Endocrine Conference

“Hypothalamic Amenorrhea”

1998Pediatric Endocrine Unit Conference

“Bone Density, Body Composition and Leptin in Women with

Hypothalamic Amenorrhea”

b. Invited presentations (Cont’d):

Massachusetts General Hospital

1998Endocrine Research Lectures

“Nutrition and Body Composition Determinants of Bone Mass in

Premenopausal Women”

Brigham and Women’s Hospital

1996Department of Infectious Diseases Conference and Journal Club

“The AIDS Wasting Syndrome in Women”

Regional, national or international contributions

1998Oral presentation of research findings

Endocrine Society

“Hypoleptinemia in Women with Hypothalamic Amenorrhea”

1998Oral presentation of research findings

Endocrine Society

“Increased Severity of Osteopenia in Women with Anorexia

Nervosa Compared to Hypothalamic Amenorrhea: The

Importance of Undernutrition as an Etiologic Factor

in Premenopausal Bone Loss”

Bibliography

Original Articles

1.Miller KK, Verma A, Snyder SH, Ross CA. Localization of an endoplasmic reticulum calcium ATPase mRNA in rat brain by in situ hybridization. Neuroscience 1991;43:1-9.

2.Grinspoon S, Corcoran C, Miller K, Biller B, Askari H, Wang E, Hubbard J, Anderson E, Basgoz N, Heller H, Klibanski A. Body composition and endocrine function in women with AIDS wasting. J Clin Endocrinol Metab. 1997;82:1332-1337.

3.Miller, KK, Parulekar, MS, Schoenfeld, E, Anderson E, Hubbard, J, Klibanski A, Grinspoon S. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: The effects of body composition and nutritional intake. J Clin Endocrinol Metab. 1998;83(7):2309-2312.

4.Miller KK, Corcoran C, Armstrong, C, Caramelli, K, Anderson EJ, Cotton D, Basgoz N, Hischhorn L, Tuomala R, Schoenfeld D, Doherty C, Mazer N, Grinspoon S. Short-term transdermal testosterone administration in women with AIDS wasting. J Clin Endocrinol Metab. 1998;83(8):2717-2725.

5.Miller KK, Daly PA, Sentochnik D, Doweiko J, Samore M, Basgoz NO, Grinspoon SK. Pseudo-Cushing’s syndrome in HIV-infected patients. Clin Infect Dis. 1998;27:68-72.

6.Grinspoon S, Corcoran C, Miller K, Wang E, Hubbard J, Schoenfeld D, Anderson E, Basgoz N, Klibanski A. Determinants of increased energy expenditure in HIV-infected women. Am J Clin Nutr. 1998; 68:720-725.

Original Articles (Cont’d)

7.Grinspoon S, Miller K, Coyle C, Krempin J, Armstrong C, Pitts S, Herzog D, Klibanski A. Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea. J Endocrinol Metab. 1999;84(6):2049-2055.

8.Hadigan C, Miller K, Corcoran C, Anderson E, Bascoz N, Grinspoon S. Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 1999;84(6):1932-1937.

9.Miller KK, Grinspoon S, Klibanski A. Cardiovascular risk markers in hypothalamic amenorrhea. Clin Endo. (In press).

10.Hadigan C, Anderson E, Miller K, Hubbard J, Herzog D, Klibanski A, Grinspoon S. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa. International Journal of Eating Disorders (In press).

Reviews

1. Miller K, Klibanski A. Amenorrhea and osteoporosis. In Kleerekoper M, Siris E, McClung M, editors. The bone and mineral manual: a practical guide. San Diego, CA: Academic Press. 1999.

2.Miller KK, Klibanski A. Amenorrheic bone loss. J Clin Endocrinol Metab. 1999; 84(6).

Abstracts

1. Grinspoon S, Miller K, Coyle C, Krempin J, Herzog D, Klibanski A. Increased severity of osteopenia in women with anorexia nervosa compared to hypothalamic amenorrhea . Endocrine Society, 1998.

2.Miller K, Corcoran C, Caramelli K, Daugherty C, Mazer N, Grinspoon S. Transdermal testosterone administration in women with AIDS wasting: a pilot study. Endocrine Society, 1998.

3.Miller K, Parulekar M, Schoenfeld E, Anderson E, Hubbard J, Klibanski A, Grinspoon S. Hypoleptinemia in women with hypothalamic amenorrhea. Endocrine Society, 1998.

4.Grinspoon S, Corcoran C, Miller K, Wang E, Hubbard J, Schoenfeld D, Anderson E, Basgoz N, Klibanski A. Determinants of increased energy expenditure in HIV-infected women . Twelfth World AIDS Conference, 1998.

5.Miller KK, Grinspoon S, Klibanski A. Hypothalamic amenorrhea as an age-independent

model of the effects of estrogen-deficiency of cardiac risk factors. Endocrine Society, 1999.

6.Miller KK, Sesmilo G, Schiller A, Burton S, Klibanski A. Androgen Deficiency in Women with Hypopituitarism. The Endocrine Society 82nd Annual Meeting, 2000.

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