Updated 30-Jul-2012


Human Research Ethics Committee

RESEARCH PROJECTS

Project Code / Title / Researcher / Approved Date / Status
2012-018 / Has the introduction of baby friendly caesarean section influenced breast feeding rates at one and three months post-natally? / A/Prof John Keogh
304 SAN Clinic
85 Fox Valley Road
WAHROONGA NSW 2076 / Received
2012-017 / Can NSW Admitted Patient Data improve the quality and coverage of the NSW Register of Congenital Conditions? / Received
2012-016 / A phase II, double-blind, placebo controlled, randomized study of GDC-0941 or GDC-0980 with fulvestrant versus fulvestrant in advanced or metastatic breast cancer in patients resistant to aromastase inhibitor therapy / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 09-Jul-2012 / Approved
2012-015 / Involving relatives in the care of a patient in the ICU setting; What factors impact on this? / Dr Tracey Thornley
Supervisor
Dean, School of Nursing Sydney
The University of Notre Dame
PO Box 944
Broadway NSW 2077 / 04-Jul-2012 / Approved
2012-014 / The successfulness of ultrasound guided removal of a Mirena device when the strings are not visible on speculum examination in an outpatient setting (A retrospective review of cases) / Dr Karen Mizia
San Ultrasound for Women
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 30-Apr-2012 / Approved
2012-013 / A multi-centre randomized controlled trial of early goal-directed therapy in patients presenting to the Emergency Department with severe sepsis in Australasia / Dr Roger Harris
Staff Specialist,
Intensive Care,
Sydney Adventist Hospital,
185 Fox Valley Road
Wahroonga NSW 2076 / 16-May-2012 / Approved
2012-012 / A randomised, open label, multicentre, Phase IIIB study comparing two Trastuzumab dosing regimens, each in combination with Ciplatin/Capecitabine chemotherapy, as first line therapy in patients with HER2-positive metastatic gastric or gastro-oesophageal junction adenocarcinoma who have not received prior treatment for metastatic disease / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 12-Mar-2012 / Approved
2012-011 / Assessment of spinal sagittal balance parameters with EOS imaging / Dr Peter Wilson
Neurosurgical trainee
2 Gregory Avenue
North Epping NSW 2121 / 18-Jun-2012 / Approved
2012-010 / Promotion of health lifestyle and risk modification for cancer survivors and their partners / caregivers (ENRICH: Exercise and Nutrition Routine Improving Cancer Health) / Dr Erica James
School of Medicine & Public Health
Faculty of Health
Level 2, David Maddison Building
Callaghan NSW 2308 / 12-Mar-2012 / Approved
2012-009 / Survey of nursing attitudes to residual neuromuscular blockade and reversal / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / 05-Mar-2012 / Approved
2012-008 / The effect of high potency Omega-3 (Omacor) on markers of oxidative stress and inflammation / Jade Guest / 28-Mar-2012 / Approved
2012-007 / Understanding clergy-parishioner relationships - when things 'go wrong' - Phase 1 / Mr Dallas O'Connor
Associate Director of Safe Place Services
Seventh-day Adventist Church (AUC) Ltd
PO Box 650
Wahroonga NSW 2076 / 12-Mar-2012 / Approved
2012-006 / Progesterone action in the human breast / Professor Christine Clarke
unknown
Westmead NSW 2145 / 20-Mar-2012 / Approved
2012-005 / Prospective Evaluation of Various Uterine Prolapse Surgical Techniques in Nepalii Women / Withdrawn
2012-004 / A retrospective analysis of outcomes following abdominal hysteropexy for uterine prolapse in Nepal (Maharati 1) / Withdrawn
2012-003 / The Study of Heart and Renal Protection - Extended Review - SHARP-ER / Dr Meg Jardine
The George Institute for Global Health,
Levl 10, King George V Building
83-117 Messenden Road
Camperdown NSW 2050 / 23-Apr-2012 / Approved
2012-002 / Designing a Prototype Clinical Information System (CIS) for Multidisciplinary Teams During Clinical Handover in Palliative Oncology / Chris Williams
Chief Information Officer
Sydney Adventist Hospital
185 Fox Valley Rd
Wahroonga NSW 2076 / 16-Jan-2012 / Approved
2012-001 / Safety and Feasibility of a Transurethral Endoscopic Procedure for the Luminal Restoration of the Prostatic Urethra: A Preliminary Investigation / A/Prof Henry Woo
Australian Clinical Trials Pty Ltd
406 San Clinic,
185 Fox Valley Road
Wahroonga NSW 2076 / 02-Feb-2012 / Approved
2011-043 / Evaluating the utility of a patient decision aid for prospective participants in the TROG RAVES prostate cancer trial. / A/Prof Henry Woo
Australian Clinical Trials Pty Ltd
406 San Clinic,
185 Fox Valley Road
Wahroonga NSW 2076 / 30-Jan-2012 / Approved
2011-042 / The complexity of treating women with breast cancer, who have underlying mental health issues. / Ms Catrina Ross
McGrath Breast Care Nurse / 05-Dec-2011 / Approved
2011-041 / A cluster randomised controlled trial in acute stroke care - changing the health system to increase the adoption of "Clot Busters" in stroke treatment - Part 2 / Professor John Watson
Associate Dean
Sydney Adventist Hospital Clinical School / 28-Mar-2012 / Approved
2011-040 / Evaluation of a 12 week Yoga Intervention on Negative Affective States, Cardiovascular and Cognitive Function in Post-Cardiac Rehabilitation Patients / Prof Hosen Kiat
Medical Director SAH Cardiac Rehabilitation Program
Cardiac Health Institute
173 Shaftsbury Road
Eastwood NSW 2122 / 13-Feb-2012 / Approved
2011-039 / Characterization of the acute postprandial effect of energy dense foods on key markers of oxidative stress and inflammation / Dr Ross Grant
CEO - Australasian Research Institute
Australasian Research Institute
185 Fox Valley Road
Wahroonga NSW 2076 / 16-Jan-2012 / Approved
2011-038 / Arm-to-arm variation when evaluating neuromuscular block: An analysis of the precision and the bias and agreement between arms when using Electromyography in abductor digiti minimi and first dorsal Interosseous. / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / Disposed
2011-037 / Arm-to-arm variation when evaluating neuromuscular block: An analysis of the precision and the bias and agreeement between arms when using Kinemyography / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / Disposed
2011-036 / Retrospective Audit of Post-Operative Analgesia after Ivor Lewis Oesophago-gastrectomy / Dr Stephanie Phillips
Consultant Anaesthetist,
Sydney Adventist Hospital Clinical School / Received
2011-035 / Randomized, open Label Multi-Centre Study Comparing Cabazitaxel at 20mg/m2 and at 25 mg/m2 Every 3 weeks in Combination with Prednisone for the Treatment of Metastatic Castration Resistant Prostate Cancer Previously Treated with Docetaxel Containing Regimen (PROSELICA). / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 12-Sep-2011 / Approved
2011-034 / Randomized, Open Label, MultiCentre, Study comparing Cabazitaxel at 25 mg/m2 and at 20 mg/m2 in Combination with Prednisone Every 3 Weeks to Docetaxel in Combination with Prednisone in Patients with Metastatic Castration Resistant Prostate Cancer not Pre-treated with Chemotherapy (FIRSTANA) / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 12-Sep-2011 / Approved
2011-033 / A randomized, double-blind, placebo-controlled, parallel group, multicenter study to evaluate cardiovascular outcomes during treatment with Lixisenatide in type 2 diabetic patients after an Acute Coronary Syndrome. / Dr Greg Fulcher / 12-Sep-2011 / Approved
2011-032 / A phase III multi-centre, randomised trial comparing adjuvant radiotherapy (RT) with early salvage RT in patients with positive margins or extraprostatic disease following radical prostatectomy. / Dr Amy Teh
Consultant in Radiation Oncology
Radiation Oncology Institute / 30-Oct-2011 / Approved
2011-031 / To investigate the ten year re-treatment rate after bladder neck incision (BNI) or transurethral incision of the prostate (TUIP) for outlet obstruction. / A/Prof Henry Woo
Australian Clinical Trials Pty Ltd
406 San Clinic,
185 Fox Valley Road
Wahroonga NSW 2076 / 05-Sep-2011 / Approved
2011-030 / Clinical study to evaluate a scaffold implant for rotator cuff lesions encountered on the supraspinatus tendon. / Associate Professor Desmond Bokor
Principal Investigator - SAH
Specialty Orthopaedics
116 Macquarie Street
Parramatta NSW 2150 / 05-Sep-2011 / Approved
2011-029 / An open label study of Abiraterone Acetate in subjects with metastatic castration-resistant prostate cancer who have progressed after Taxane-based chemotherapy. / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 04-Jul-2011 / Approved
2011-028 / Incidence of residual neuromuscular blockade in Australian post anaesthetic care units / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / 18-Feb-2011 / Approved
2011-027 / A Phase 3, Randomized, Double-blind, Multicenter Trial Comparing Orteronel (TAK-700) Plus Prednisone With Placebo Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer that has progressed During or Following Docetaxel-based Therapy. / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 20-Jun-2011 / Approved
2011-026 / The pharmacokinetic differences in serum and saliva levels of resveratrol, lycopene complex, NAD+ and oxidative stress. / Dr Ross Grant
CEO - Australasian Research Institute
Australasian Research Institute
185 Fox Valley Road
Wahroonga NSW 2076 / 29-Aug-2011 / Approved
2011-025 / Do whole and/or highly processed foods or food ingredients promote adverse physiological responses? / Dr Ross Grant
CEO - Australasian Research Institute
Australasian Research Institute
185 Fox Valley Road
Wahroonga NSW 2076 / Rejected
2011-024 / Improving psychosocial outcomes for carers of people with cancer: a randomised controlled trial / Dr Joanne Shaw
Surgical Outcomes Research Centre
Building 89 Level 9
PO Box M157
Missenden Road NSW 2050 / 20-Jun-2011 / Approved
2011-023 / A Phase 3, randomized, double-blind trial of Pegylated Liposomal Doxorubicin (PLD) plus AMG 386 or placebo in women with recurrent partially platinum sensitive or resistant epithelial ovarian, primary peritoneal or fallopian tube cancer. / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 13-Jun-2011 / Approved
2011-022 / Direct intra-patient comparison of evoked electromyography and acceleromyography during induced neuromuscular blockade in anaesthetised humans. / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / 14-Jun-2011 / Approved
2011-021 / Direct intra-patient comparison of evoked electromyography and kinemyography during induced neuromuscular blockade in anaesthetised humans. / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / 14-Jun-2011 / Approved
2011-020 / Comparison of evoked electromyographic responses in three different muscle groups of the hand following induced muscle relaxation in humans under general anaesthesia. / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / 14-Jun-2011 / Approved
2011-019 / Comparison of gastric volumes and pH in lean and obese patients, determined by endoscopy. / Dr Paul Stewart
AMO
Consultant Anaesthesia
PO Box 82
Wahroonga NSW 2076 / 14-Jun-2011 / Approved
2011-018 / PREVAIL: A multinational Phase 3, randomized, double-blind placebo-controlled efficacy and safety study of oral MDV3100 in chemotherapy-naive patients with progressive metastatic prostate cancer who have failed androgen deprivation therapy (MDV3100-03) / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 30-May-2011 / Approved
2011-017 / Current practice of neuro-muscular blockade in Australia. A cross-sectional survey of attitudes and practice of anaesthetists in 2011. / Dr Stephanie Phillips
Consultant Anaesthetist,
Sydney Adventist Hospital Clinical School / 06-Jun-2011 / Approved
2011-016 / Bi-National Colorectal Cancer Audit / Dr Stuart Pincott / 06-Jun-2011 / Approved
2011-015 / Multicentre, single-arm, open label, clinical trial intended to provide early access to Cabazitaxel in patients with metastatic hormone refractory prostate cancer previously treated with a Docetaxel-containing regimen and to document safety of Cabazitaxel in these patients (Cabazitaxel clinical trial) / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 09-May-2011 / Approved
2011-014 / Phase II study to investigate the ability of macrophage inhibitory cytokine-1 (MIC-1) and associated plasma biomarkers to predict response to chemotherapy in patients with metastatic hormone-refractory prostate cancer. / Dr Gavin Marx
Sydney Haematology & Oncology Clinics
Sydney Haematology and Oncology Clinics
Clinical Trials Unit
Sydney Adventist Hospital
185 Fox Valley Road
Wahroonga NSW 2076 / 19-Apr-2011 / Approved
2011-013 / The Australian diabetes, obesity and lifestyle study / Dr Elizabeth Barr
Epidemiologist Baker IDI Heart & Diabetes Institute
Tues/Frid / 20-Apr-2011 / Approved
2011-012 / Attitudes of SAN community to clinical student teaching in a private hospital setting. / Dr Stephanie Phillips
Consultant Anaesthetist,
Sydney Adventist Hospital Clinical School / 11-Apr-2011 / Approved
2011-011 / Porto Cath insertion / Dr Sumit Lumba
Medical Oncology Advanced Trainee under Dr Eisen Liang and Dr Gavin Marx / Rejected
2011-010 / Grounded theory research investigating organisational change in specified Australian hospitals to determine the applicability of existing generic organisational change management models to the not-for-profit hospital environment. / Prof Elizabeth More
PhD Supervisor / 30-May-2011 / Approved
2011-009 / Randomised controlled double-blind trial of targeted intra-crural ropivicaine for post-operative analgesia after laparoscopic fundoplication. / Dr Stephanie Phillips
Consultant Anaesthetist,
Sydney Adventist Hospital Clinical School / Abandoned
2011-008 / A pilot study to evaluate a new blood test for the detection of prostate cancer using antibody arrays. / A/Prof Henry Woo
Australian Clinical Trials Pty Ltd
406 San Clinic,
185 Fox Valley Road
Wahroonga NSW 2076 / 30-May-2011 / Approved
2011-007 / Rhinology Tissue Bank / A/Prof Richard Harvey
St Vincent's Hospital
Sydney Ear Nose & Throat Clinic
Sydney Ear Nose & Throat Clinic
354 Victoria Street
Darlinghurst NSW 2010 / 11-Jul-2011 / Approved
2011-006 / Assessment of the effect of oral supplementation with resveratrol and/or lycopene on key markers of oxidative stress over time and skin health following acute UV exposure. / Dr Ross Grant