Homework 2: End date: 10. 08. 2016
1. The enzyme increase rate of reaction by decrease the …………………………………
2. Trypsin is specific for cleavage of ………………..bondadjacent to …………………….. amino acid
3. Serine proteases identical in the …………………………. but different in the …………………………...
4. Hydrophobic Pocket of chymotrypsin contains two glycine andserinebut the hydrophobic Pocket of trypsin containtwo glycine and ………………………………..
5.The six major classes of glycosaminoglycans (GAGs)?
1. 2. 3.
4. 5. 6.
6. Proteoglycans are made up of core ……………………… and ……………………………..
7. The oligosaccharide attached to the protein through an N- or an O-………………………….Link
8. Glycoproteins are made up from ……………………………..and……………………………………..
9. What is the different between Proteoglycans and Glycoproteins?
10.Which of the following statements about fatty acid is correct?
a. Have general formula R-COOH
b. insoluble in water
c. Hydrophobic (non polar) or amphipathic(polar and non polar)
d.all a,b and c.
11. The Functions of glycoproteins are
1. 2.
3. 4.
10. Essential fatty acids are:
A) Mammals they cannot synthesis. B) Mammals they can synthesis.
C) Saturated fatty acid. D) None of these.
11. What is a fat-soluble vitamin? ………………………………………………………..
12. The configuration of the double bonds in unsaturated fatty acids is generally ………………………
14. Phospholipase C converts glycerophospholipids to …………………………………...
15. phospholipase D converts glycerophospholipids to …………………………………....
16. phosphlipase A2 (present in snake, bee, and wasp venom) catalyze the hydrolysis of the ester bonds and produce ……………………………… resulting hydrolysis RBCs
17. Fatty acids are generally stored as………………………………….
18. Triacylglycerolscannot form bilayers because it is………………………………properties.
19. Circle the fatty acid in each pair that has the higher melting temperature.
A) 18:1∆9 and 18:2∆9, 12
B) 18:0 and 18:1∆9
C) 18:0 and 16:0
20. From the following data for a hypothetical enzyme, choose the most effective substrate, Explain. The substrate is…………………..…?why?......
Substrate / Km / Kcat / Kcat/Km (M-1 S-1)A / 0.1 / 2 X10-2 / 2 X10-3
B / 1 / 2 X102 / 2 X102
C / 10 / 2 X101 / 2
D / 100 / 2 X105 / 2 X103
21.Lysozyme catalyzes hydrolytic cleavage of …………………………. bond
22. Chymotrypsin, example of the use of both ……………………………………………………………... catalysis.
23. Hexokinase, example of …………………………………….………………….
24. Enolase (phosphopyruvatehydratase), example of………………………………………………………………………………………..catalysis.
25. Which of the following statements aboutGlycerophospholipids is correct?
a. The most abundant in membranes
b. amphipathic
c. phosphatidate is glycerophospholipids
d. Plasmalogens have a vinyl ether linkage rather than ester linkage is one of the major types of glycerophospholipids.
e. all of these
26. Which of the following statements aboutSphingolipidsis correct?
a. abundant in tissues of the central nervous
b. amphipathic.
c. Ceramideis the metabolic precursors of all sphingolipids
d. all of these
27. Which one of the following is not a sphingolipids?
a. Ceramide b. .Sphingomyelins c. Cerebrosides d. Plasmalogens
e. Gangliosides
28. Fatty acids are joined to other molecules by an…………..………………bond or linkage.
29. The sugar chain in oligosaccharide is attached to the protein through an N- or an O-glycosidic link by:
A) Asparagine side chain OR either a serine or threonine respectively.
B) Tyrosine or valine respectively.
C) Isoleucine or glycine respectively.
D) None of these