June 23, 2004

His Excellency Mu'ammar al-Gaddafi

Leader of the Revolution

Office of the Leader of the Revolution

Tripoli

Great Socialist People's Libyan Arab Jamahiriya

Dear Your Excellency al-Gaddafi:

As leading virologists and other scientists and physicians, we join our health professional colleagues internationally in calling on you urgently to commute the death sentences imposed by the Benghazi Criminal Court in Libya on five Bulgarian nurses and one Palestinian physician. We also respectfully ask your government to review the procedures that have led to the targeting of these foreign health workers in this affair. The individuals have been charged and convicted of deliberately infecting more than 400 children with HIV while working in al-Fateh Children’s Hospital. Prominent independent scientific experts have concluded, however, that the systematic infection was not perpetrated by those accused. Many of the children were infected prior to the arrival of these health practitioners, and the evidence further shows that unsanitary health conditions are to blame. It is an unfortunate reality that in many countries throughout the world, particularly those in Africa and Asia, inadequate health conditions, training, and care can hasten the spread of HIV/AIDS.

Those sentenced to death are Kristiana Malinova Valcheva, Nasya Stojcheva Nenova, Valentina Manolova Siropulo, Valya Georgieva Chervenyashka, Snezhanka Ivanova Dimitrova, and Ashraf Ahmad Jum’a.

Libyan authorities took an appropriate step in investigating the cause of the nosocomial HIV infection at al-Fateh Children’s hospital when the Gaddafi Foundation appointed Professor Vittorio Colizzi, who is with the Tor Vegatta University in Rome, and Professor Luc Montagnier, co-discoverer of HIV, the virus that causes AIDS, as international scientific consultants. However, we believe the Benghazi Criminal Court has disregarded the explicit findings of these prominent physicians and has proceeded without a firm grasp of the scientific realities.

After several trips to Libya, which included a comprehensive and thorough investigation of the al-Fateh Children’s hospital, Drs. Montagnier and Colizzi highlighted the unlikelihood of a deliberate injection by the accused health workers and concluded that “all the genetic analyses performed strongly indicate that the nosocomial infection in Benghazi Children’s Hospital has been caused by a single. . . subtype of A/G HIV-1...by one. . . HIV infected child who was originally infected by his mother through vertical transmission. This infection was already present in the Benghazi Hospital in April 1997 [before the foreign health workers arrived]. . . and was still operating in March 1999.”

Dr. Montagnier’s assertion that the infections were caused by poor medical conditions is consistent with the international community’s recognition that unsterile medical equipment can and does transmit HIV. Outbreaks with similar causes have been documented in Egypt, Romania, and the Kalmyk Autonomous Region of Russia. In fact, according to the World Health Organization, it is estimated that 260,000 HIV infections occur each year because of medical injections given with unsterile needles and syringes.

When HIV infections are transmitted through medical procedures or other unsterile conditions at health facilities, the transmissions do not occur because of ill will on the part of health care workers. Rather, the causes tend to be systemic to the health facility or health systems, including improper training of health workers, a high workload, insufficient supplies, or inadequate infection prevention and control procedures.

That more than 400 children at al-Fateh Children’s Hospital were infected with HIV is truly tragic. However, accusing health professionals of deliberately infecting the children with HIV, contrary to the evidence, and sentencing these health professionals to death, will not help protect other patients from a similar fate. Policies that promote strong infection prevention and control regime will provide significant protection. We believe it is critical that Libyan authorities, with international assistance as needed, investigate and determine the conditions at al-Fateh Children’s Hospital that enabled these children to become infected, and ensure that such conditions no longer exist at that or any other Libyan health facility. The World Health Organization’s Regional Office for the Eastern Mediterranean can be contacted to assist with the investigation or direct the Libyan authorities to those who are best positioned to do so.

We are glad to hear that most of the children infected with HIV at al-Fateh Children’s Hospital are still alive, and that Libyan authorities are providing for their treatment at home and abroad. Children, like adults, can be successfully treated with anti-retroviral medication, keeping them alive for many years.

Due to the scientific evidence and to credible reports that the health workers were tortured into false confessions, we believe that the defendants have suffered extreme prejudice in their case. Accordingly, we urge the Libyan authorities to dismiss the case, and to release to their home countries the imprisoned medical personnel who were invited to your country to help treat the sick. We urge you to ensure that these health professionals are protected, given any medical attention they may need, and are not further abused while still in detention.

Sincerely,

Michael Adler, MD, FRCP

Professor of Medicine

University College London

ENGLAND

Arash Alaei, MD

Co-director, Pars Curative Researchers Institute for HIV/DU/STI

Shaheed Beheshti University of Medical Sciences

Co-director, TB/HIV International Programs

National Research Institute of Tuberculosis and Lung Disease

Tehran & Kermanshah

IRAN

Kamiar Alaei, MD

Co-director, Pars Curative Researchers Institute for HIV/DU/STI

Shaheed Beheshti University of Medical Sciences

Co-director, TB/HIV International Programs

National Research Institute of Tuberculosis and Lung Disease

Tehran & Kermanshah

IRAN

John G. Bartlett, MD

Johns Hopkins University

Baltimore, MD

USA

Stephane Blanche, MD

Unité d Immunologie-Hematologie Departement

Hospital Necker-Enfants Malades

Paris

FRANCE

Rafael E. Campo, MD

Infectious Diseases Research Unit

Division of Infectious Diseases

University of Miami School of Medicine

Miami, FL

USA

Vittorio Colizzi, MD, PhD

Professor, University of Tor Vergata

Rome

ITALY

Douglas T. Dieterich, MD

Vice Chair and Chief Medical Officer

The Mount Sinai Medical Center

New York, NY

USA

Jan Desmyter, MD, PhD

Rega Instituut

Leuven

BELGIUM

Aida Seif El-Dawla, MD

Professor of Psychiatry, Ain Shams University

Founding Member, El Nadim Center for Psychological Rehabilitation of Victims of Violence

Chairperson, Egyptian Association against Torture

Cairo

EGYPT

Wafaa El-Sadr, MD, MPH

Harlem Hospital Center

Columbia University

New York, NY

USA

Robert C. Gallo, MD

Director, Institute of Human Virology and

Division of Basic Science

University of Maryland Biotechnology Institute

Baltimore, MD

USA

Ashley T. Haase, MD
Regents’ Professor and Head, Department of Microbiology
Director, AHC Biomedical Genomics Center
Director, Minnesota Division, Great Lakes Regional Center for AIDS Research
University of Minnesota
Minneapolis, MN

USA

Daniel R. Kuritzkes, MD

Associate Professor of Medicine

Harvard Medical School

Vice-President, Board of Directors

HIV Medicine Association

Cambridge, MA

USA

Professor Thomas Lehner, CBE, MD

Professor of Basic and Applied Immunology

Guy's King's and St Thomas' Hospitals

King's College London

ENGLAND

Haytham Manna, MD, PhD

Board of Directors, Arab Commission for Human Rights

FRANCE

Abdallah Mansour, MD

Director, El Nadim Centre for Psychological Management and

Rehabilitation of Victims of Violence

Cairo

EGYPT

Moncef Marzouki, MD

Associate Professor of Public Health

University of Paris

FRANCE

Kenneth Mayer, MD

Director, Brown University AIDS Program

Professor of Medicine and Community Health, Brown University

Medical Research Director, Fenway Community Health

Boston, MA

USA

Luc Montagnier, MD, PhD

Co-founder, World Foundation for AIDS Research and Prevention

Co-director, Program for International Viral Collaboration

FRANCE

Jeffrey Nadler, MD

Director, Clinical Research, Division of Infectious Diseases

University of South Florida College of Medicine

Tampa, FL

USA

Dr. Rafael Nájera

Chief, Department of Viral Pathogenesis

National Center for Microbiology

Instituto de Salud Carlos III

Madrid

SPAIN

Jumana Odeh, MD, MPH

Director, Palestinian Happy Child Centre

WEST BANK AND GAZA

Mobeen Rathore, MD

Chief, Division of Pediatric Infectious Diseases/Immunology

Professor and Assistant Chairman for Research and Academic Affairs

Department of Pediatrics

University of Florida Health Sciences Center

Jacksonville, FL

USA

Douglas D. Richman, MD

Professor of Pathology and Medicine

Director, Center for AIDS Research

Florence Seeley Riford Chair in AIDS Research

University of California San Diego

La Jolla, CA

USA

Michael Saag, MD

Professor of Medicine

Director, AIDS Outpatient Clinic

University of Alabama at Birmingham

Birmingham, AL

USA

Robert T. Schooley, MD

Tim Gill Professor and Head, Division of Infectious Diseases

Director, Colorado Center for AIDS Research

University of Colorado Health Sciences Center

Denver, CO

USA

Valerie E. Stone, MD, MPH

Associate Chief, General Medicine Unit

Director, Primary Care Residency Program

Massachusetts General Hospital

Harvard Medical School

Boston, MA

USA

Anita Vaughn, MD

Medical Director, Homeless Healthcare Clinic

Newark Department of Health and Human Services

Newark, NJ

USA

Paul Volberding, MD

President, HIV Medicine Association

Professor of Medicine and Vice Chair of Medicine

University of California, San Francisco (UCSF)

Co-Director UCSF-GIVI Center for AIDS Research

Chairman of the Board, International AIDS Society-USA

San Francisco, CA

USA

Hans Wigzell, MD, PhD

Director, Karolinska Institute

SWEDEN

S. Bruce Williams, MD

University of New Mexico School of Medicine

Albuquerque, NM

USA