Joan C. Han, MD
Date of Preparation:December 30, 2015
Joan C. Han, MD
CURRICULUM VITAE
EDUCATION:
Harvard College (9/1991-6/1995), AB, Magna cum Laude in Biochemical Sciences, 1995
Harvard Medical School (9/1995-6/1999), MD, 1999
Boston Combined Residency Program in Pediatrics at Boston Children’s Hospital and Boston Medical Center, Boston, MA (Internship 7/1999-6/2000, Residency 7/2000-6/2002)
Clinical Research Fellowship, Division of Endocrinology, Nemours Children’s Clinic, Jacksonville, FL (7/2003-6/2004)
Pediatric Endocrinology Fellowship, National Institutes of Health, Bethesda, MD (7/2004-
6/2007)
HONORS/AWARDS:
2014Mentor of Kristina Decker (graduate student), Winner of Prader-Willi Syndrome-Association (USA) Travel Award for Trainees and Junior Faculty
2014Mentor of Daniela Reyes-Capo (medical student), Winner of Outstanding Poster Award, NIHPostbac Poster Day: Endocrine and Metabolic Characterization of Alström Syndrome
2012Mentor of Alyson Hanish (graduate student), Winner of Endocrine Society Presidential Poster Competition: Pineal Hypoplasia and Decreased Melatonin Secretion in Patients with PAX6 Haploinsufficiency due to WAGR Syndrome or PAX6 Mutations
2012Endocrine Society Travel Award (for early career investigators and junior faculty)
2011NIH Clinical Center Bench-to-Bedside Award (Principal Investigator):Amitriptyline for the Treatment of BDNF Haploinsufficiency
2010NIH Merit Award: In recognition of outstanding contributions to clinical patient care and research on growth, metabolism, obesity, and rare genetic diseases associated with disordered energy homeostasis
2010Rare Diseases Clinical Research Network Travel Award for the 2nd Conference on Clinical Research for Rare Diseases
2010The 5th International Congress of the Growth Hormone Research Society and the Insulin-Like Growth Factor Society Travel Grant Award
2010Foundation for Prader-Willi Research Grant (Co-Investigator): The Relationship between Serum Brain-Derived Neurotrophic Factor (BDNF) Levels, BDNF Haplotypes and Neurocognitive Performance in Children with Prader-Willi Syndrome (PWS)
2010NICHD Intramural Bench-to-Bedside Award (Principal Investigator): The Role of BDNF in Autism Spectrum Disorder and Cognitive Function
2010Prader-Willi Syndrome Association (USA) Best Idea Grant for Hyperphagia Research (Principal Investigator): Brain-Derived Neurotrophic Factor in Prader-Willi Syndrome and MC4R Function-Altering Mutations
2009NIH Clinical Center Bench-to-Bedside Award (Co-Investigator):FTO and Eating in Absence of Hunger
2009Nominee, Rare Disease Day Research Hall of Fame, National Organization for Rare Disorders
2008Mentor of KavithaAnandalingam (high school student), Intel Science Talent Search Semi-Finalist: Associations between FTO genotype and eating behavior phenotype in children
2008NIH Fellows Award for Research Excellence
2007NIH Fellows Award for Research Excellence
2007Ethan Sims Obesity Society Young Investigator Award
2007NIH Clinical Center Bench-to-Bedside Award (Principal Investigator):WAGR Syndrome-Clinical Characterization and Correlation with Genotype
2007Genentech Clinical Fellows Travel Grant to Endocrine Society Meeting
2007Pediatric Academic Societies Young Investigator Travel Award
2007Lawson Wilkins Pediatric Endocrine Society Travel Grant Award
2006Endocrine Society Travel Grant Award
2006Lawson Wilkins Pediatric Endocrine Society Travel Grant Award
2005Lawson Wilkins Pediatric Endocrine Society Travel Grant Award
2004Genentech Clinical Fellows Travel Grant to Endocrine Society Meeting
1994Phi Beta Kappa
1994John Harvard Scholarship
1994Elizabeth Cary Agassiz Scholarship
1993John Harvard Scholarship
1993Elizabeth Cary Agassiz Scholarship
1992John Harvard Scholarship
1992Elizabeth Cary Agassiz Scholarship
1992Detur Book Prize
1991National Science Scholar
UNIFORMED SERVICE:
Commissioned Officer in the United States Public Health Service (9/20/2004-12/19/2010), attained rank of O-5 (Commander) prior to honorable release from active duty
BOARD CERTIFICATION:
General Pediatrics (10/15/2002-Current)
Pediatric Endocrinology (11/19/2007-Current)
American Board of Obesity Medicine (12/31/2013-Current)
LICENSURE:
Medical Doctor, Tennessee, MD0000050763, issued 10/30/2013, active
Medical Doctor, Florida, ME84327, issued 2/23/2002, retired
SOCIETY MEMBERSHIPS:
Since 2012Society for Pediatric Research
Since 2007American Society of Human Genetics
Since 2006Obesity Society
Since 2005Pediatric Endocrine Society
Since 2004Endocrine Society
Since 1999American Academy of Pediatrics
Since 1996American Medical Association
Since 1995Massachusetts Medical Society
UNIVERSITY/INSTITUTE APPOINTMENTS:
Associate Professor, University of Tennessee Health Science Center, Memphis (7/2014-Current)
Director, Pediatric Obesity Program, UT/Le Bonheur Children’s Hospital, Memphis (1/2014-Current)
Clinical Associate Professor, University of Tennessee Health Science Center, Memphis (1-6/2014)
Assistant Clinical Investigator, National Institutes of Health, Bethesda, MD (7/2009-6/2014)
Senior Clinical Fellow, National Institutes of Health, Bethesda, MD (7/2007-6/2009)
Assistant Professor of Pediatrics, University of Florida, Jacksonville, FL (7/2002-6/2003)
HOSPITAL CLINICAL APPOINTMENTS:
Le Bonheur Children’s Hospital, Memphis, TN: Attending Physician, 8/2014-Current, active
National Institutes of Health Clinical Research Center, Bethesda, MD: Attending Physician, 7/2004-7/2014, inactive
Shands Jacksonville Medical Center, Jacksonville, FL: Attending Physician, 7/2002-6/2003, inactive
TEACHING EXPERIENCE:
Lecturer, National Institute of Child Health and Human DevelopmentPost-baccalaureate Fellow
Course: Becoming an Effective Scientist (1 hour/year, 2006-2012)
Attending Physician, National Institutes of Health Pediatric Endocrinology Fellowship Program (5 hours/week teaching/supervising fellows and residents, 2007-2014)
Attending Physician, University of Tennessee Health Science Center (4 hours/week teaching/supervising fellows and residents, 2014-Current)
INVITED LECTURES:
Digestive Disease Week, American Gastroenterological Association, San Diego, CA, May 2016: Impact of Genetics on Pathogenesis and Response to Treatment in Pediatric Obesity
13thInternational Neurotrophin Conference, Monterey, CA, April 2016: Neurotrophins and Disease
6th Annual Sanford Rare Disease Symposium, Sanford Research, Sioux Falls, SD,February 2016: Rare Genetic Obesity Disorders: Insights for Energy Balance in the General Population
14th Annual Symposium on Pediatric Diabetes and Endocrinology, Icahn School of Medicine at Mount Sinai, New York, NY, November 2015: Genetics of Obesity
2nd Annual UTHSC Pediatric Obstructive Sleep Apnea Symposium, Memphis, TN, April 2015: Pediatric Obesity and Obstructive Sleep Apnea
UTHSC Neuroscience Symposium on the Neurobiology of Appetite, Memphis TN, April 2015:
Brain-Derived Neurotrophic Factor and Obesity
West Tennessee Psychiatric Association Meeting, Memphis TN, March 2015:
Pediatric Obesity and Psychotropic Medications
11th Annual Mid-South Conference on the Complex Newborn, Memphis, TN, January 2015:
Measuring Body Composition of Babies
UTHSC Medical Student Pediatric Interest Group, Memphis, TN, December 2015:
Pediatric Obesity
University of Tennessee Family Medicine Residency Program Conference at Jackson-Madison County General Hospital, Jackson, TN, October 2014: Pediatric Obesity
Pediatric Grand Rounds, Le Bonheur Children’s Hospital, Memphis, TN, September 2014: Pediatric Obesity
16th International Congress of Endocrinology & The Endocrine Society’s 96th Annual Meeting & Expo, Chicago, IL, June 2014: Brain Derived Neurotrophic Factor (BDNF) in Rare and Common Forms of Pediatric Obesityat the Symposium on Pediatric Obesity: New Peptides and Pathways
UTHSC Endocrinology Grand Rounds, Memphis, TN, March 2014:
Brain-Derived Neurotrophic Factor in Obesity and Neurocognitive Function
NICHD Exchange: Healthy Lifestyles Symposium, Bethesda, MD, February 2014:
Prevention and Treatment of Obesity
Aniridia Foundation International and University of Virginia Scientific Symposium, Charlottesville, VA, August 2013: Hormones and Metabolism in PAX6 Haploinsufficiency
Department of Neuroscience Research Meeting, Mayo Clinic, Jacksonville, FL, January 2013: Brain-Derived Neurotrophic Factor in Obesity and Neurocognitive Function
Division of Endocrinology, Diabetes, and Nutrition Grand Rounds, University of Maryland School of Medicine, Baltimore, MD, July 2012: Brain-Derived Neurotrophic Factor and Obesity
International WAGR Syndrome Association Meeting, Gaithersburg, MD, July 2012: Phenotype- Genotype Correlation in WAGR Syndrome
Eighth Annual NICHD Fellows Retreat, National Zoo Conference Center, WashingtonDC, May 2012: Brain-Derived Neurotrophic Factor in Obesity and Neurocognitive Function
Rare Syndromic Body Fat Disorders Workshop, NIDDK and Office of Rare Diseases Research, NIH, Bethesda, MD, February 2012: Brain-Derived Neurotrophic Factor in WAGR Syndrome and Non-Syndromic Obesity
Toward a Clinical Definition of Leptin Resistance Workshop, NIDDK, Bethesda, MD, February 2011: Does hyperleptinemia serve as an indicator of leptin resistance in humans with leptin signaling defects?
Rare Disease Day at NIH, Bethesda, MD, February 2011: WAGR Syndrome: Clinical Characterization and Correlation with Genotype
Research Conference for the Obesity and Diabetes Clinical Research Section, NIDDK, Phoenix, AZ, January 2011: Brain-Derived Neurotrophic Factor and Human Energy Homeostasis
The Obesity Society Annual Scientific Meeting, San Diego, CA, October 2010: Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome
Foundation for Prader-Willi Research Annual Meeting, Bethesda, MD, September 2010: Brain-Derived Neurotrophic Factor and Prader-Willi Syndrome
International WAGR Syndrome Association Meeting, Gaithersburg, MD, July 2010: Autism and Cognitive Function in WAGR Syndrome
Obesity in Children with Developmental and/or Physical Disabilities Workshop, NICHD, Bethesda, MD, July 2010: Overview of Childhood Obesity
Alström Syndrome International Conference, Helen, GA, June 2010:Hyperphagia and Food Management Issues
Uniformed ServicesUniversity Research Symposium, Bethesda, MD, May 2010: Association between Variants in the FTO Gene and Loss of Control over Eating
International WAGR Syndrome Association Meeting, Gaithersburg, July 2009: Impaired Pain Perception and Short Stature in WAGR Syndrome
International Conference on Hyperphagia, Prader-Willi Syndrome Association (USA), Baltimore, MD, June 2009: Hyperphagia and Obesity in WAGR Syndrome
International WAGR Syndrome Association Meeting, Vienna, VA, July 2007: BDNF and Obesity in WAGR Syndrome
International WAGR Syndrome Association Meeting, Yardley, PA, July 2006: NIH WAGR Syndrome Research Study
COMMITTEES:
Service to Institution:
2012-2014NICHD Representative, NIH Clinical Center Pediatric Care Committee
2010-2014NIH Clinical Research Information System Quality Review Committee
2005-2006NICHD Clinical Fellows Representative, NIH Fellows Committee
2005-2006Member, NIH Fellows Career Development Committee
Medical Advisory Board:
2012-CurrentInternational WAGR Syndrome Association
Conference Organization:
Member, Organizing Committee, 2nd International Conference on Hyperphagia, Pennington Biomedical Research Center, Baton Rouge LA, October 17-21, 2012
PROFESSIONAL ACTIVITIES:
Associate Editor for Journal
Since 2015Pediatric Associate Editor for the International Journal of Obesity
Review Editor for Journal
Since 2015Frontiers in Endocrinology - Structural and Molecular Endocrinology
Ad Hoc Reviewer for Journals:
Since 2014Annals of Clinical Biochemistry
Since 2012Gene
Since 2012Pediatric Diabetes
Since 2011British Journal of Nutrition
Since 2010American Journal of Medical Genetics: Part A
Since 2010American Journal of Physiology - Regulatory, Integrative and Comparative Physiology
Since 2010European Journal of Human Genetics
Since 2010International Journal of Obesity
Since 2009Journal of Clinical Endocrinology and Metabolism
Since 2008Journal of Pediatrics
Since 2008Pediatrics
Reviewer for Abstracts:
Since 2014Endocrine Society
Since 2014Digestive Disease Week
Since 2011Pediatric Academic Societies
Reviewer for Grant Proposals:
Since 2013Foundation for Prader-Willi Research
Since 2012Great Ormond Street Hospital Children's Charity
Since 2011Pediatric Endocrine Society
Since 2010Action Medical Research, UK
Symposium Chair
Chair, Symposium on Preventing and Reversing Obesity in Minority Children at the 98th Annual Meeting of the Endocrine Society, Boston, MA, April 2016
Chair, University of Tennessee Health Science Center James H. Horner, MD Distinguished Visiting Professorship, Obesity Prevention and Treatment Symposium, Memphis, TN September 2015
Chair, Obesity Symposium-New Insights on Epidemiology, Investigational Models, and
Therapeutic Targets, 26th Annual NIH Research Festival, Bethesda, MD, October 2012
GRADUATE STUDENT AND JUNIOR FACULTY MENTORING:
Graduate Student Mentor:
Alyson Hanish, PhD, University of Iowa and National Institute of Nursing Research Graduate Partnership Program (8/2011-1/2015), Sleep-Related Phenotypes: Adolescence and PAX6Haploinsuffiency; currently Postdoctoral Research Associate at the University of Nebraska Medical Center
Postdoctoral Fellow Mentor:
Liam McAllan, PhD (from Teagasc Food Research Center & University College Cork,
Ireland), Postdoctoral Fellow, Department of Pediatrics, University of Tennessee Health Science Center, 4/2015 to present
Graduate Student Thesis Committee Member:
Innocence Harvey, PhD candidate, Department of Physiology, University of Tennessee
Health Science Center, 9/2014 to present
Junior Faculty Research Mentoring Committee Member:
Rebecca Krukowski, PhD, Assistant Professor, Department of Preventive Medicine,
University of Tennessee Health Science Center, 2/2015 to present
RESEARCH SUPPORT:
Memphis Research Consortium$1,000,0007/1/14-6/30/17 PI: J Han
“Genetic, Behavioral, and Environmental Determinants of Metabolic Health”
Childhood Brain Tumor Foundation $35,00010/1/12-9/30/14
Co-PIs: P Wolters and K Warren; Co-Investigator: J Han
"A Randomized Controlled Trial Evaluating a Physical Activity Intervention to Improve Cognitive Late Effects in Children with Brain Tumors Treated with Cranial Radiation"
NIH Bench-to-Bedside Research Award $270,00010/1/10-9/30/12
Co-PIs: J Han, B Martin, S Maudsley
“Amitriptyline for the Treatment of BDNF Haploinsufficiency”
Prader-Willi Syndrome Association USA$50,0007/1/10-6/30/12
Co-PIs: J Han and J Yanovski
“Brain-Derived Neurotrophic Factor in Prader-Willi Syndrome and MC4R Function-Altering Mutations”
Foundation for Prader-Willi Research Grant $50,0006/1/10-5/31/12
PI: A Haqq; Co-Investigator: J Han
“The Relationship between Serum Brain-Derived Neurotrophic Factor (BDNF) Levels, BDNF Haplotypes and Neurocognitive Performance in Children with Prader-Willi Syndrome (PWS)”
NICHD Bench-to-Bedside Research Award$100,00010/1/09-9/30/11
Co-PIs: J Han and K. Martinowich
“The Role of BDNF in Autism Spectrum Disorder and Cognitive Function”
NIH Bench-to-Bedside Research Award$270,00010/1/08-9/30/10
Co-PIs: J Yanovski and M Tanofsky-Kraff; Co-Investigator: J Han
“FTO and Eating in Absence of Hunger”
NIH Bench-to-Bedside Research Award $200,00010/1/06-9/30/08
Co-PIs: J Han, B Lu
“WAGR Syndrome: Clinical Characterization and Correlation with Genotype”
BOOK CHAPTERS:
1)Han JC, Yanovski JA. Chapter 21: Intensive Therapies for the Treatment of Pediatric Obesity. In Jelalian E, Steele RG, eds. Handbook of Child and Adolescent Obesity. New York, NY: Springer Science + Business Media, LLC (2008).
2)Han JC.Rare Syndromes and Common Variants of the Brain-Derived Neurotrophic Factor Gene in Human Obesity. In Tao YX, ed. Progress in Molecular Biology and Translational Science, Volume 140: Genetics of Monogenic and Syndromic Obesity. New York, NY: Elsevier B.V. (2016).
PEER-REVIEWED JOURNAL ARTICLES:
1)Chu TC, Ogidigben M, Han JC, Potter DE. Allicin-induced hypotension in rabbit eyes. J OculPharmacol 1993;9(3):201-9.PMID: 8228529
2)Han J, Lawson L, Chu TC, Potter D, Han G, Han P. Modification of catalytic properties of chicken liver fructose 1,6-bisphosphatase by allicin. BiochemMolBiolInt 1993;31(6):1007-15.PMID: 8193584
3)Han JC, Han GY. A procedure for quantitative determination of tris(2-carboxyethyl)phosphine, an odorless reducing agent more stable and effective than dithiothreitol. Anal Biochem 1994;220(1):5-10.PMID: 7978256
4)Han J, Lawson L, Han G, Han P. A spectrophotometric method for quantitative determination of allicin and total garlic thiosulfinates. Anal Biochem 1995;225(1):157-60.PMID: 7778769
5)Chu TC, Burch JL, de Paula Brotto MA,Creazzo TL, Han J, Han GY, Potter, DE. Elevation of intracellular Ca2+ concentration in rabbit nonpigmented ciliary epithelial cells by allicin. Comp BiochemPhysiol C PharmacolToxicolEndocrinol 1996;115(1):89-94.PMID: 8983172
6)Han J, Payne V, Yen S, Han G, Han P. Use of tris(2-carboxyethyl)phosphine for quantitation of iodine and iodate. Anal Biochem 1996;242(1):150-2.PMID: 8923979
7)Han J, Yen S, Han G, Han P. Quantitation of hydrogen peroxide using tris(2-carboxyethyl)phosphine. Anal Biochem 1996;234(1):107-9.PMID: 8742092
8)Han J, Chu T-C, Han G, Browne J, Brown I, Han P. Spectrophotometric assay for hypochlorite/hypochlorous acid using tris(2-carboxyethyl)phosphine. Microchemical Journal 1998;58(2):218-24.
9)Han J, Clark C, Han G, Chu TC, Han P. Preparation of 2-nitro-5-thiobenzoic acidusingimmobilized Tris(2-carboxyethyl)phosphine. Anal Biochem 1999;268(2):404-7.PMID: 10075833
10)Han J, Story T, Han G. A Spectrophotometric Method for Quantitative Determination of Bromine Using Tris(2-carboxyethyl)phosphine. Journal of Chemical Education 1999;76(7):976-7.
11)Han JC, Balagopal P, Sweeten S, Darmaun D, Mauras N. Evidence for Hypermetabolism in Boys with Constitutional Delay of Growth and Maturation. J ClinEndocrinolMetab 2006;91(6):2081-6.PMID: 16551727
12)Gray J, Yeo GS, Cox JJ, Keogh JM, Morton J, Adlam AR, Yanovski JA, El Gharbawy A, Han JC, Tung YC, Hodges JR, Raymond FL, O’ Rahilly S, Farooqi IS. Hyperphagia, severe obesity, impaired cognitive function and hyperactivity associated with functional loss of one copy of the BDNF gene. Diabetes 2006;55(12):3366-71.PMCID: PMC2413291
13)Fleisch AF, Agarwal N, Roberts MD, Han JC, Theim KR, Vexler A,Troendle J, Yanovski SZ, Yanovski JA.Influence of Serum Leptin on Weight and Body Fat Growth in Children at High Risk for Adult Obesity. J ClinEndocrinolMetab 2007;92(3):948-54.PMCID: PMC1862865
14)Drinkard B, Roberts MD, Ranzenhofer LM, Han JC, Yanoff LB, Merke DP, Savastano DM, Brady S, Yanovski JA.Oxygen-Uptake Efficiency Slope as a Determinant of Fitness in Overweight Adolescents. Med Sci Sports Exerc 2007;39(10):1811-6.PMCID: PMC2266873
15)Olney RC, Prickett TC, Yandle TG, Espiner EA, Han JC, Mauras N. Amino-Terminal Propeptide of C-Type Natriuretic Peptide (NTproCNP) and Linear Growth in Children: Effects of Puberty, Testosterone and Growth Hormone. J ClinEndocrinolMetab 2007;92(11):4294-8.PMID: 17684048
16)Han JC, Rutledge MS, KozloskyM, Salaita CG, Gustafson JK, Keil MF, Fleisch AF, Roberts MD, Ning C, Yanovski JA. Insulin Resistance, Hyperinsulinemia, and Energy Intake in Overweight Children. J Pediatr 2008;152(5):612-7.PMCID: PMC2276579
17)Han JC, Liu QR, Jones M, Levinn RL, Menzie CM, Jefferson-George KS, Adler-Wailes DC, Sanford EL, Lacbawan FL,Uhl GR, Rennert OM, Yanovski JA. Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome. N Engl J Med 2008;359(9):918-27.PMCID: PMC2553704
18)Xu S, Han JC, Morales A, Menzie CM, Williams K, Fan YS. Characterization of 11p12-14 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism. Cytogenet and Genome Res2008;122(2):181-7; erratum in:Cytogenet Genome Res. 2009;124(1):112.PMID: 19096215
19)Roberts MD, Drinkard B, Ranzenhofer LM, Salaita CG, Sebring NG, Brady SM, Pinchbeck C, Hoehl J, Yanoff LB, Savastano DM, Han JC, Yanovski JA. Prediction of maximal oxygen uptake by bioelectrical impedance analysis in overweight adolescents. J Sports Med Phys Fitness. 2009;49(3):240-5.PMCID: PMC3027125
20)Savastano DM, Tanofsky-Kraff M, Han JC, Ning C, Sorg RA, Roza CA, Wolkoff LE, Anandalingam K, Jefferson-GeorgeKS, Figueroa RE, Sanford EL, Brady S, Kozlosky, Schoeller DA, Yanovski JA. Energy Intake and Energy Expenditure among Children with Polymorphisms of the Melanocortin-3 Receptor. Am J ClinNutr 2009;90(4):912-20.PMCID: PMC2744620
21)Solomon BD, Pineda-Alvarez DE, Balog JZ, Hadley D, Gropman AL, Nandagopal R, Han JC, Hahn JS, Blain D, Brooks B, Muenke M. Compound heterozygosity for mutations in PAX6 in a patient with complex brain anomaly, neonatal diabetes mellitus, and microophthalmia.Am J Med Genet A. 2009 Nov;149A(11):2543-6.PMCID: PMC2783496
22)Tanofsky-Kraff M*, Han JC*, Anandalingam K, Shomaker LB, Columbo KM, Wolkoff LE, Kozlosky M, Elliott C, Ranzenhofer LM, Roza CA, Yanovski SZ, Yanovski JA. The FTO Gene rs9939609 Obesity Risk Allele and Loss of Control over Eating. Am J ClinNutr 2009;90:1483–8. (*these authors contributed equally)PMCID: PMC2777464
23)Gustafson JK, Yanoff LB, Easter BD, Brady SM, Keil MF, Roberts MD, Sebring NG, Han JC, Yanovski SZ, Hubbard VS, Yanovski JA. The stability of metabolic syndrome in children and adolescents. J ClinEndocrinolMetab 2009;94:4828-34.PMCID: PMC2795665
24)Van den Berg L, Delemarre-van de Waal H, Han JC, Ylstra B, Eijk P, Nesterova M, Heutink P, StratakisCA. Investigation of a Patient with a Partial Trisomy 16q including the Fat mass and Obesity Associated gene (FTO): Fine Mapping and FTO Gene Expression Study. Am J Med Genet A 2010;152A(3):630-7.PMCID: PMC3031344
25)Han JC, Lawlor DA, Kimm SY. Childhood Obesity. Lancet 2010; 375: 1737–48.PMCID: PMC3073855
26)Han JC, Muehlbauer MJ, Cui HN, Newgard CB, Haqq AM. Lower Brain-Derived Neurotrophic Factor (BDNF) in Patients with Prader-Willi Syndrome (PWS) Compared to Obese and Lean Control Subjects. J ClinEndocrinolMetab 2010;95(7):3532-6.PMCID: PMC2928902
27)ShomakerLB,Tanofsky-Kraff M, Young-Hyman D, Han JC, Yanoff LB, Brady SM, Yanovski SZ, Yanovski JA. Psychological Symptoms and Insulin Sensitivity in Adolescents. Pediatr Diabetes 2010;11:417-23.PMCID: PMC2942090
28)Han JC, Damaso L, Welch S, Balagopal P, Hossain J, Mauras N. Effects of Growth Hormone and Nutritional Therapy in Boys with Constitutional Growth Delay: A Randomized Controlled Trial. J Pediatr2011;158:427-32.PMID: 20961566
29)Feuillan PP*, Ng D†, Han JC†, Sapp JC, Wetsch K, Spaulding E, Zheng YC, Caruso RC, Brooks B, Johnston JJ, Yanovski JA, Biesecker LG. Leptin Resistance in Patients with Bardet-Biedl Syndrome. J ClinEndocrinolMetab2011;96(3):E528-35 (*submitted posthumously in her honor; †these authors contributed equally).PMCID: PMC2928902