Scientific contribution and abstract submission

Deadline and instructions

Deadline for submission of the abstract: May 30th 2014

Notification to authors for oral or poster communications after selection by the scientific committee: before July1st, 2014.

The text should be in English and should include the title, the first name, the name and addresses of the authors (see example).

The corresponding author should be indicated with “*”.

The position of the speaker (first author) should be indicated (PhD, post-doc,…).

Priority will be given to young scientists for oral communications.

Join the CV of the speaker to your abstract

IMPORTANT : it is mandatory to give us the NAME of the SPEAKER when you submit your abstract

Presentation of the abstract (mandatory)

Font : Arial

Title: 12pt, bold, all-capital letters

Text body: 10 pt, justification, line spacing: simple

Margins: left and right and all other margins: 2.5 cm

The abstract should not exceed one page

Please use all-capital letters for headlines and names. Store your text file in format Word for Windows (.doc) and submit your contribution to the registration site.

https://www.cborg.info/hnesas/

Save the file as: FIRST NAME_SESSION (1, 2 or 3)

Give 5 keywords maximum


Example (fiction):

File name: TARA_SESSION2

phenolic derivatives from Acacia nehaleta with Antioxidant and ANTICANCER PROPERTIES

Scarlett TARA*1, Enji NAJA2, Abdy IBRAM2, Aude MAROSE2, Naman RAHIM2, Mila REYBI2

1 Centre National de la Recherche, Rue des trois Pyramides, Le Caire, Egypte

² Université de Toulouse, UPS, UMR 152 IRD (PHARMA-DEV), 118, route de Narbonne, 31062 Toulouse cedex 9 - France

e-mail:

Positionof the speaker: post-doc

Session: 2

Keywords: antioxidants, medicinal plants, polyphenols, cancer

Phenolic compounds are widely distributed in higher plants. Several epidemiological studies have shown that an increased dietary intake of natural phenolic antioxidants correlates with reduced coronary heart diseases [1]. These compounds have also been found to exhibit many health-related properties that are based on their antioxidant and radical scavenging activities. These properties include anticancer, antiviral, and anti-inflammatory activities, effects on capillary fragility, and an ability to inhibit human platelet aggregation [2].

In the present study, the aqueous methanolic flowers extract from Acacia nehaleta (L.), family Fabaceae,plant growing in Egypt, containing tannin derivatives and flavonoids acylated by gallotannin, has been investigated for redox properties. The total polyphenols showed excellent antioxidant potency when tested by radical scavenging methods. The effective dose 50 (ED50) of the extract was compared with that of standard antioxidants using UV-visible absorbance and electron paramagnetic resonance (EPR) based assays.

Cell lines derived from primary and recurrent brain tumors from the same patient and cells selected for resistance to chemotherapeutic agents were used to identify antiproliferative effects of aqueous methanolic flowers extract from Acacia nehaleta (L.). Results indicated that Acacia nehaleta (L.) not only inhibits cellular growth in recurrent and drug resistant brain tumor cell lines, but also demonstrates an increased inhibitory effect when used in conjunction with some chemotherapeutic agents.

References

[1] M. G. L. Hertog, E. J. M. Feskeens, C. H. Hollman, M. B. Katan, D. Kromhout. Dietary antioxidant flavonoids and risk of coronary heart disease. Lancet 1993, 342, 1007-1011.

[2] P. O. Benavente-Garcısa, J. Castillo, F. Marin, A. Ortuno, J. Rıo. Use and properties of citrus flavonoids. J. Agric. Food Chem. 1997, 45, 4505-4515

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