Garcia Barrado M. J., Pastor M. F., Iglesias-Osma M. C.,Carpéné C.& Moratinos J.: Comparative

2010

Garcia Barrado M. J., Pastor M. F., Iglesias-Osma M. C.,Carpéné C.& Moratinos J.: Comparative effects of idazoxan, efaroxan, and BU 224 on insulin secretion in the rabbit: not only interaction with pancreatic imidazoline I2 binding sites. Health, 2010, 2, 112-121.

X. FIORAMONTI, N. MARSOLLIER, Z. SONG, K.A. FAKIRA, R. PATEL, S. BROWN, T. DUPARC, A. PICA-MENDEZ, N.M. SANDERS, C. KNAUF, P. VALET, R.J. McCRIMMON, A. BEUVE, C. MAGNAN & V.H. ROUTH. Ventromedial hypothalamic nitric oxide production is necessary for hypoglycemia detection and counter-regulation. Diabetes, 59: 519-528, 2010.

R. GUZMÁN-RUIZ, B. SOMOZA, M. GIL-ORTEGA, B. MERINO, V. CANO, C. ATTANÉ, I. CASTAN-LAURELL, P. VALET, M.S. FERNÁNDEZ-ALFONSO & M. RUIZ-GAYO.Sensitivity of cardiac carnitine palmitoyltransferase to malonyl-CoA is regulated by leptin: similarities with a model of endogenous hyperleptinemia. Endocrinology, 151: 1010-1018, 2010.

J.A. POSPISILIK, D. SCHRAMEK, H. SCHNIDAR, S.J.F. CRONIN, N.T. NEHME, X. ZHANG, C. KNAUF, P.D. CANI, K. AUMAYR, J. TODORIC, M. BAYER, A. HASCHEMI, M. ORTHOFER, G.G. NEELY, G. DIETZL, A. MANOUKIAN, M. FUNOVICS, G. PRAGER, O. WAGNER, D. FERRANDON, F. ABERGER, C. HUI, H. ESTERBAUER, J.M. PENNINGER. Drosophila whole genome screen reveals Hedgehog-signaling as a key regulator of brown/white adipose cell fate. Cell, 140: 148-160, 2010.

Z. IFFIU-SOLTESZ, E. WANECQ, A. LOMBA, F. PELLATI, E. SZÖKÖ, S. BOUR, J.F. WOODLEY, F.I. MILAGRO, A.J. MARTINEZ, M.P. PORTILLO, P. VALET & C. CARPENE. Chronic benzylamine administration in the drinking water improves glucose tolerance and reduces circulating cholesterol in high-fat diet-fed mice. Pharmacol. Res.

M. Bot, I. Bot, R. Lopez-Vales, C.H.A. Van de Lest, J.S. Saulnier-Blache, J.B. Helms, S. David, T.J.C. Van Berkel & E.A.L. Biessen. Atherosclerotic Lesion Progression Changes Lysophosphatidic Acid Homeostasis to Favor Its Accumulation. Am. J. Physiol.

M. DAVID, E. WANNECQ, F. DESCOTES, S. JANSEN, B. DEUX, J. RIBEIRO, C.M. SERRE, S GRES, N. BENDRISS-VERMARE, M. BOLLEN, S. SAEZ, J. AOKI, J.S. SAULNIER-BLACHE, P. CLEZARDIN & O. PEYRUCHAUD. Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts. Plos One.

2009

Caspar-Bauguil S., Cousin B., Bour S., Casteilla L., Penicaud L. &Carpéné C.: Adipose tissue lymphocytes: types and roles. J. Physiol. Biochem., 2009, in press.

Wanecq E., Prévot D. &Carpéné C.: Lack of direct insulin-like action of visfatin/Nampt/PBEF1 in human adipocytes. J. Physiol. Biochem., 2009, in press.

Atgié C., Sauvant P., Ambid L. &Carpéné C.: Weight loss of Siberian hamsters (Phodopus sungorus sungorus) exposed to short photoperiod cannot be explained by alteration of antilipolytic or “de novo” lipogenic activities in white adipocytes. J. Physiol. Biochem., 2009, in press.

Iffiú-Soltész Z., Wanecq E., Prévot D., Grès S. &Carpéné C.Histamine oxidation in mouse adipose tissue is controlled by the AOC3 gene-encoded amine oxidase. Inflamm. Res., 2009, in press.

Iffiú-Soltész Z., Prévot D. &Carpéné C.:Influence of prolonged fasting on monoamine oxidase and semicarbazide-sensitive amine oxidase activities in rat white adipose tissue. J. Physiol. Biochem., 2009, 65, 11-23.

O. MASSON, C. CHAVEY, C. DRAY, A. MEULLE, D. DAVIAUD, D. QUILLIOT, C. MULLER, P. VALET & E. LIAUDET-COOPMAN. LRP1 gene expression is up-regulated in obese human and mouse adipose tissue and controls adipogenesis. PLoS One, 4: e7422, 2009.

S. BOUR, S. CASPAR-BAUGUIL, Z. IFFIU-SOLTESZ, M. NIBBELINK, B. COUSIN, M. MIILUNIEMI, M. SALMI, C. STOLEN, S. JALKANEN, L. CASTEILLA, L. PENICAUD, P. VALET & C. CARPENE. SSAO/VAP-1 deficiency causes mild obesity without increased leukocyte infiltration into adipose tissue. Am. J. Pathol. 174: 1075-1083, 2009.

F. CHICHE, M. LE GUILLOU, G. CHETRITE, F. LASNIER, I. DUGAIL, C. CARPENE, M. MOLDES & B. FEVE. The antidepressant phenelzine alters differentiation of cultured human and mouse preadipocytes. Mol. Pharmacol. 75 : 1052-1061, 2009.

I. WOCLAWEK-POTOCKA, J. KOMIYAMA, J.S. SAULNIER-BLACHE, E. BRZEZICKA, M. BAH, K. OKUDA, D. SKARZYNSKI. Lysophosphatic acid modulates prostaglandin secretion in the bovine uterus. Reproduction. 137: 95-105, 2009.

E. BOUTET, H. EL MOURABIT, M. PROT, M. NEMANI, E. KHALLOUF, O. COLARD, M. LE MAURICE, A.M. DURAND-SCHNEIDER, Y. CHRETIEN, S. GRES, C. WOLF, J.S. SAULNIER-BLACHE, J. CAPEAU, J. MAGRE. Seipin deficiency alters fatty acid D9 desaturation and lipid droplet formation in Berardinelli-Seip congenital lipodystrophy. Biochime. 91 : 796-803, 2009.

2008

C. DRAY, C. KNAUF, D. DAVIAUD, A. WAGET, M. BULÉON, J. BOUCHER, P. CANI, C. ATTANE, C. GUIGNÉ, C. CARPÉNÉ, R. BURCELIN, I. CASTAN-LAURELL & P. VALET. Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab. 8: 437-445, 2008.

I. CASTAN-LAURELL, M. VITKOVA, D. DAVIAUD, C. DRAY, M. KOVACIKOVA, Z. KOVACOVA, J. HEJNOVA, V. STICH & P. VALET. Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ. Eur. J. Endocrinol. 158: 905-910, 2008.

A. MAZZUCOTELLI, C. RIBET, I. CASTAN-LAURELL, D. DAVIAUD, C. GUIGNE, D LANGIN & P. VALET. The transcriptional co-activator PGC-1a up regulates apelin in human and mouse adipocytes. Reg. Pep. 150 : 33-37, 2008.

O. KUNDUZOVA, N. ALET, N. DELESQUE-TOUCHARD, L. MILLET, C. DRAY, C. MULLER, I. CASTAN-LAURELL, P. SCHAEFFER, J.P. HERAULT, P. SAVI, F. BONO & P. VALET. Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes. FASEB J. 22 : 4146-4153, 2008.

G. FERRY, N. MOULHARAT, J.P. PRADERE, P. DESOS, A. TRY, A. GENTON, A. GIGANTI, M. BLEUCHER-GAUDIN, M. LONCHAMPT, M. BERTRAND, J.S. SAULNIER-BLACHE, G.C. TUCKER, A. CORDI, J.A. BOUTIN. S32826 : a nanomolar inhibitor of autotaxin. discovery, synthesis and applications as a pharmacological tool. J. Pharmacol. Exp. Ther. 327 : 809-819, 2008.

J.P. PRADERE, J. GONZALES, J. KLEIN, P. VALET, S. GRES, D. SALANT, J.L. BASCANDS, J.S. SAULNIER-BLACHE & J. SCHANSTRA. LPA and Kidney fibrosis. Biochem. Biophys. Acta. 1781: 582-587, 2008.

L.A. VAN MEETEREN, V. BRINKMANN, J.S. SAULNIER-BLACHE, K.R. LYNCH & V.H. MOOLENAR. FTY720-phosphate inhibits the activity of autotaxin, a metastasis-enhancing lysophospholipase D. Cancer Letters. 266: 203-208, 2008.

C. KNAUF, P.D. CANI, A. AIT-BELGNAOUI, A. BENANI, C. DRAY, C. CABOU, A. COLOM, M. ULDRY, S. RASTRELLI, E. SABATIER, N. GODET, A. WAGET, L. PENICAUD, P. VALET & R. BURCELIN. Brain GLP-1 signaling controls the onset of high-fat diet-induced hyperinsulinemia, insulin resistance and reduced energy expenditure. Endocrinology. 149: 4768-4777, 2008.

A. MEULE, B. SALLES, D. DAVIAUD, P. VALET & C. MULLER. Positive regulation of DNA double strand break repair activity during adipogenesis: implication of the DNA dependent protein kinase. PLoS ONE, 3 : e3345, 2008.

C. CARPENE, V. ABELLO, Z. IFFIU-SOLTESZ, N. MERCIER, B. FEVE & P. VALET. Limitation of adipose tissue enlargement in rats chronically treated with semicarbazide-sensitive amine oxidase and monoamine oxidase inhibitors. Pharmacol. Res. 57: 426-434, 2008.

A.E. BIGORGNE, L. BOUCHET-DELBOS, S. NAVEAU, I. DAGHER, S. PREVOT, I. DURAND-GASSELIN, J. COUDERC, P. VALET, D. EMILIE & G. PERLEMUTER. Obesity-induced lymphocyte hyperresponsiveness to chemokines: a new mechanism of fatty liver inflammation in ob/ob mice. Gastroenterology. 134: 1459-1469, 2008.

A. GIGANTI, M. RODRIGUEZ, B. FOULD, N. MOULHARAT, F. COGÉ, P. CHOMARAT, J.P. GALIZZI, P. VALET, J.S. SAULNIER-BLACHE, J.A. BOUTIN & G. FERRY. Murine and Human Autotaxin alpha, beta, gamma isoforms: gene organization, tissue distribution, and biochemical characterization. J. Biol. Chem. 283: 7776-7789, 2008.

K. NADRA, A.S. DE PREUX CHARLES, J.J. MEDARD, W.T. HENDRIKS, G.S. HAN, S. GRES, G.M. CARMAN, J.S. SAULNIER-BLACHE, M.H.G. VERHEIJEN, & R. CHRAST. Phosphatidic acid mediates demyelination in Lpin1 mutant mice. Gene and Development, 15: 1647-1661, 2008.

2007

C. CARPENE, Z. IFFIU-SOLTESZ, S. BOUR, D. PREVOT & P. VALET. Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats. Pharmacol. Res. 56: 522-530, 2007.

J.P. PRADERE, S. GRES, J. KLEIN, C. GUIGNE, E. NEAU, P. VALET, D. CALISE, J. CHUN, J.L. BASCANDS, J.S. SAULNIER-BLACHE & J. SCHANSTRA. LPA1 receptor activation promotes renal interstitial fibrosis. J. Am. Soc. Nephrol., 18: 3110-3118, 2007.

S. GARCIA-VICENTE, F. YRAOLA, L. MARTI, E. GONZALEZ-MUNOZ, M.J. GARCIA-BARRADO, C. CANTO, A. ABELLA, S. BOUR, R. ARTUCH, C. SIERRA, N. BRANDI, C. CARPENE, J. MORATINOS, M. CAMPS, M. PALACIN, X. TESTAR, A. GUMA, F. ALBERICIO, M. ROYO, A. MIAN, A.ZORZANO. Oral insulin-mimetic compounds that act independently of insulin. Diabetes. 56: 486-93, 2007.

J.P. PRADERE, E. TARNUS, S. GRES, P. VALET & J.S. SAULNIER-BLACHE. Secretion and lysophospholipase D activity of autotaxin by adipocytes are controled by N-Glycosylation and signal peptidases. Biochem. Biophys. Acta, 1771: 93-102, 2007.

Z. IFFIU-SOLTESZ, D. PREVOT, S. GRES, S. BOUR, E. SZÖKÖ, C. KNAUF, R. BURCELIN, A. FERNANDEZ-QUINTELA, A. LOMBA, F. MILAGRO & C. CARPENE. Influence of benzylamine acute and chronic administrations on glucose tolerance in diabetic and obese mice fed a very high-fat diet. J. Physiol. Biochem., 63: 305-316, 2007.

V. ROLLI, M. RADOSAVLJEVIC, V. ASTIER, C. MACQUIN, I. CASTAN-LAURELL, V. VISENTIN, C. GUIGNE, C. CARPENE, P. VALET, S. GILFILLAN & S. BAHRAM. Lipolysis is altered in MHC class I Zinc-Alpha2-glycoprotein deficient mice. FEBS letters, 581: 394-400, 2007.

S. BOUR, D. DAVIAUD, S. GRES, C. LEFORT, D. PREVOT, A. ZORZANO, M. WABITSCH, J.S. SAULNIER-BLACHE, P. VALET & C. CARPENE. Adipogenesis-related increase of Semicarbazide-Sensitive Amine Oxidase and Monoamine Oxidase in human adipocytes. Biochimie, 89: 916-925, 2007.

P. CLERC, M.G. COLL-CONSTANS, H. LULKA, S. BROUSSAUD, C. GUIGNE, S. LEUNG-THEUNG-LONG, C. PERRIN, C. KNAUF, C. CARPENE, L. PENICAUD, C. SEVA, R. BURCELIN, P. VALET, D. FOURMY &M. DUFRESNE. Involvement of cholecystokinin2 receptor in food intake regulation : hyperphagia and increased fat deposition in cholecystokinin2 receptor-deficient mice. Endocrinology, 148: 1039-1049, 2007.

C. DRAY, D. DAVIAUD, C. GUIGNÉ, P. VALET & I. CASTAN-LAURELL. Caffeine reduces TNF-a up-regulation in human adipose tissue primary culture. J. Physiol. Biochem. 63: 329-336, 2007.

D. PREVOT, S. SOLTESZ, V. ABELLO, E. WANECQ, P. VALET, M. UNZETA & C. CARPENE. Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats. Pharmacol. Res. 56: 70-79, 2007.

J. MINET-RINGUET, P.C. EVEN, P. VALET, C. CARPENE, V. VISENTIN, D. PREVOT, D. DAVIAUD, A. QUIGNARD-BOULANGER, D. TOME & R. DE BEAUREPAIRE. Alteration of lipid metabolism and gene expression in rat adipocytes during chronic olanzapine treatment. Mol. Psychiat. 12: 562-571, 2007.

S. BOUR, D. PREVOT, C. GUIGNE, C. STOLEN, S. JALKANEN, P. VALET & C. CARPENE. Semicarbazide-sensitive amine oxidase substrates fail to induce insulin-like effects in fat cells from AOC3 knockout mice. J. Neural. Trans. 114: 829-833, 2007.

2006

L.A. VAN MEETEREN, P. RUURS, C. STORTELERS, P. BOUWMAN, M.A.VAN ROOIJEN, J.P. PRADERE, T.R. PETTIT, M.J. WAKELAM, J.S. SAULNIER-BLACHE, C.L. MUMMERY, W.H. MOOLENAAR, J. JONKERS. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol. Cell. Biol. 26: 5015-22, 2006.

E. WANECQ, S. BOUR, P. WERWAERDE, F. SMIH, P. VALET & C. CARPENE. Increased monoamine oxidase and semicarbazide-sensitive amine oxidase activities in white adipose tissue of obese dogs fed a high fat diet. J. Physiol. Biochem. 62 : 113-124, 2006.

A. GALINIER, A. CARRIERE, Y. FERNANDEZ, C. CARPENE, M. ANDRE, S. CASPAR-BAUGUIL, J.P. THOUVENOT, B. PERIQUET, L. PENICAUD, L. CASTEILLA. Adipose tissue proadipogenic redox changes in obesity. J. Biol. Chem. 281: 12682-7, 2006.

D. DAVIAUD, J. BOUCHER, C. DRAY, C. GUIGNE, S. GESTA, D. QUILLIOT, A. AYAV, O. ZIEGLER, C. CARPENE, J.S. SAULNIER-BLACHE, P. VALET & I. CASTAN-LAURELL. TNFalpha up-regulates apelin expression in human and mouse adipose tissue. FASEB J. 20: 1528-1530, 2006.

C. FERRAND, A. REDONNET, D. PREVOT, C. CARPENE & C. ATGIE. Prolonged treatment bêta3-adrenergic agonist CL 316243 induces adipose tissuewith the remodeling in rat but not in guinea pig: 1) fat store depletion and bêta3-adrenergic responses. J. Physiol. Biochem.,desensitization of 62: 89-100, 2006.

C. DUFFAUT, S. BOUR, D. PREVOT, L. MARTI, X. TESTAR, A. ZORZANO & C. CARPENE. Prolonged treatment with the bêta3-adrenergic agonist CL 316243 induces adipose tissue remodeling in rat but not in guinea pig: 2) modulation of glucose uptake and monoamine oxidase activity. J. Physiol. Biochem., 62: 101-112, 2006.

S. BOUR, M.C. IGLESIAS-OSMA, L. MARTI, P. DURO, M.J. GARCIA-BARRADO, M.F. PASTOR, D. PREVOT, V. VISENTIN, P. VALET, J. MORATINOS & C. CARPENE. The imidazoline I2-site ligands BU 224 and 2-BFI inhibit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes. Eur. J. Pharmacol. 552: 20-30, 2006.

C. CHAVEY, J. BOUCHER, M.N. MONTHOUEL-KARTMANN, E.H. SAGE, I. CASTAN-LAURELL, P. VALET, S. TARTARE-DECKERT & E. VAN OBBERGHEN. Regulation of Secreted Protein Acidic and Rich in Cysteine during Adipose Conversion and Adipose Tissue Hyperplasia. Obesity. 14: 1890-1897, 2006.

C. CARPENE, D. DAVIAUD, J. BOUCHER, S. BOUR, V. VISENTIN, S. GRES, C. DUFFAUT, E. FONTANA, X. TESTAR, J.S. SAULNIER-BLACHE & P. VALET. Short- and long-term insulin-like effects of monoamine oxidase and semicarbazide-sensitive amine oxidase substrates in cultured adipocytes. Metabolism. 55: 1397-1405, 2006.

2005

J. MAZEREEUW-HAUTIER, S. GRES, M. FANGUIN, C. CARIVEN, J. FAUVEL, B. PERRET, H. CHAP, J.P. SALLES, J.S. SAULNIER-BLACHE. Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activity. J. Invest. Dermatol. 125: 421-7, 2005.

J. BOUCHER, D. QUILIOT, J.P. PRADERES, M.F. SIMON, S. GRES, C. GUIGNE, D. PREVOT, G. FERRY, J.A. BOUTIN, C. CARPENE, P. VALET & J.S. SAULNIER-BLACHE. Potential involvement of adipocyte insulin-resistance in obesity-associated up-regulation of adipocyte lysophospholipase D / autotaxin expression. Diabetologia, 48: 569–577, 2005.

V. VISENTIN, J. BOUCHER, S. BOUR, D. PREVOT, I. CASTAN, C. CARPENE, & P. VALET. Influence of high-fat feeding on amine oxidase activity in white adipose tissue of mice prone or resistent to diet-induced obesity. J. Physiol. Biochem. 61: 343-352, 2005.

J. BOUCHER, B. MASRI, D. DAVIAUD, S. GESTA, C. GUIGNE, A. MAZZUCOTELLI, I. CASTAN-LAURELL, I. TACK, B. KNIBIEHLER, C. CARPENE, Y. AUDIGIER, J.S. SAULNIER-BLACHE & P. VALET. Apelin, a newly identified adipokine up regulated by insulin and obesity. Endocrinology, 146: 1764-1771, 2005.

S. BOUR, V. VISENTIN, D. PREVOT, D. DAVIAUD, J.S. SAULNIER-BLACHE, C. GUIGNE, P. VALET & C. CARPENE. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J. Physiol. Biochem. 61: 371-380, 2005.

M.F. SIMON, D. DAVIAUD, S. GRES, C. GUIGNE, M. WABITSCH, J. CHUN, P. VALET & J.S. SAULNIER-BLACHE. Lysophosphatidic acid inhibits adipocyte differentiation via LPA1 receptor-dependent down regulation of PPARg2 expression. J. Biol. Chem. 280: 14656-14662, 2005.

C. CARPENE, S. BOUR, V. VISENTIN, F. PELLATI, S. BENVENUTI, M.C. IGLESIAS-OSMA, M.J. GARCIA-BARRADO & P. VALET. Amine oxidase substrates for impaired glucose tolerance correction. J. Physiol. Biochem., 61: 405-420, 2005.

V. VISENTIN, S. BOUR, J. BOUCHER, D. PREVOT, P. VALET, C. ORDENER, A. PARINI & C. CARPENE. Glucose handling in streptozotocin-induced diabetic rats is improved by tyramine but not by the amine oxidase inhibitor semicarbazide. Eur. J. Pharmacol., 522: 139-146, 2005.

M.C. IGLESIAS-OSMA, S. BOUR, M.J. GARCIA-BARRADO, V. VISENTIN, M.F. PASTOR, X. TESTAR, L. MARTI, G. ENRIQUE-TARANCON, P. VALET, J. MORATINOS & C. CARPENE. Methylamine but not mafenide mimics insulin-like activity of the semicarbazide-sensitive amine oxidase-substrate benzylamine on glucose tolerance and on human adipocyte metabolism. Pharmacol. Res. 52: 475-484, 2005.

J. BOUCHER, I. CASTAN-LAURELL, D. DAVIAUD, C. GUIGNE, M. BULEON, C. CARPENE, J.S. SAULNIER-BLACHE & P. VALET. Adipokine expression profile in adipocytes of different mouse models of obesity. Horm. Metab. Res. 37: 761-777, 2005.

2004 (main publications)

A. BOUCHARABA, C.M. SERRE, S. GRES, J.S. SAULNIER-BLACHE, J.C. BORDET, J. GUGLIELMI, P. CLEZARDIN, O. PEYRUCHAUD. Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer. J. Clin. Invest.114: 1714-25, 2004.

V. VISENTIN, D. PREVOT, V. DURAND DE SAINT FRONT, N. MORIN-CUSSAC, C. THALAMAS, J. GALITSKY, P. VALET, A. ZORZANO & C. CARPENE. Alteration of amine oxidase activity in the adipose tissue of obese subjects. Obesity Res.,12: 547-555, 2004.

M.C. IGLESIAS-OSMA, M.J. GARCIA-BARRADO, V. VISENTIN, M.F. PASTOR-MANSILLA, S. BOUR, D. PREVOT, P. VALET, J. MORATINOS & C. CARPENE. Benzylamine exhibits insulin-like effects on glucose disposal, glucose transport and fat cell lipolysis in rabbits and diabetic mice.J. Pharmacol. Exp. Ther.,309: 1-9, 2004.

2003 (main publications)

S. GESTA, K. LOLMEDE, D. DAVIAUD, M. BERLAN, A. BOULOUMIE, M. LAFONTAN, P. VALET & J.S. SAULNIER-BLACHE. Culture of human adipose tissue explants leads to profound alteration of adipocyte gene expression. Horm. Metab. Res., 35: 158-163, 2003.

G. FERRY, E. TELLIER, A. TRY, S. GRES, I. NAIME, M.F. SIMON, M. RODRIGUEZ, J. BOUCHER, I. TACK, S. GESTA, P. CHOMARAT, M. DIEU, M. RAES, J.P. GALIZZI, P. VALET, J. BOUTIN & J.S. SAULNIER-BLACHE. Autotaxin is released from adipocytes, catalyses lysophosphatidic acid synthesis, and activates preadipocyte proliferation: up-regulated expression with adipocyte differentiation and obesity. J. Biol. Chem., 278: 18162-18169, 2003.

2002 (main publications)

S. GESTA, M.F. SIMON, A. REY, D. SIBRAC, A. GIRARD, M. LAFONTAN, P. VALET & J.S. SAULNIER-BLACHE. Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis. J. Lipid Res., 43: 904-910,2002.

M.F. SIMON, A. REY, I. CASTAN-LAURELL, S. GRES, D. SIBRAC, P. VALET & J.S. SAULNIER-BLACHE. Expression of ecto-lipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes: involvement in the control of lysophosphatidic acid production. J. Biol. Chem., 277: 23131-23136, 2002.

N. MORIN, V. VISENTIN, D. CALISE, L. MARTI, A. ZORZANO, X. TESTAR, P. VALET, Y. FISCHER & C. CARPENE. Tyramine stimulates glucose uptake in insuline-sensitive tissues in vitro and in vivo via its oxidation by amine oxidases. J. Pharmacol. Exp. Ther.,303: 1238-1247, 2002.

J. BOUCHER, I. CASTAN-LAURELL, S. LE-LAY, D. GRUJIC, D. SIBRAC, S. KRIEF, M. LAFONTAN, B. LOWELL, I. DUGAIL, J.S. SAULNIER-BLACHE & P. VALET. Human alpha2A-adrenergic receptor gene expressed in transgenic mice adipose tissue under the control of its regulatory elements. J. Mol. Endocrinol.,29: 251-264, 2002.

2001 (main publications)

N. AL-MAKDISSY, A. BIANCHI, M. YOUNSI, E. PICARD, P. VALET, N. MARTINET, M. DAUCA & M. DONNER. Down regulation of peroxisome proliferator-activated receptor  gene expression by sphingomyelins. Febs letters,493: 75-79, 2001.

C. PAGES, D. Daviaud, S. an, s. krief, M. lafontan, P. Valet & j.S. Saulnier-blache. Endothelial Differentiation Gene-2 receptor is involved in lysophosphatidic acid-dependent control of 3T3F442A preadipocyte proliferation and spreading. J. Biol. Chem.,276: 11599-11605,2001.

V. VISENTIN, N. MORIN, E. FONTANA, D. PREVOT, J. BOUCHER, I. CASTAN, P. VALET, D. GRUJIC & C. CARPENE. Dual action of octopamine on glucose transport into adipocytes: inhibition via beta3-adrenoceptor activation and stimulation via oxidation by amine oxidases. J. Pharmacol. Exp. Ther., 299: 96-104, 2001.

S. LE LAY, J. BOUCHER, A. REY, I. CASTAN-LAURELL, S. KRIEF, P. FERRE, P. VALET & I. DUGAIL. Decreased resistin expression in mice with different sensitivities to high-fat diet. Biochem. Biophys. Res. Com., 289: 564-567, 2001.

S. GESTA, J. HEJNOVA, M. BERLAN, D. DAVIAUD, F. CRAMPES, V. STICH, P. VALET & J.S. SAULNIER-BLACHE. In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue.Horm. Metab. Res.,33: 701-707, 2001.

2000 (main publications)

P. VALET, D. GRUJIC, J. WADE, M. ITO, M.C. ZINGARETTI, V. SOLOVEVA, S. R. ROSS, R.A. GRAVES, S. CINTI, M. LAFONTAN & B.B. LOWELL.Expression of human 2-adrenergic receptors in adipose tissue of 3-adrenergic receptor deficient mice promotes diet-induced obesity. J. Biol. Chem.,275: 34797-34802, 2000.

j.S. SAULNIER-BLACHE, A. GIRARD, M.F. SIMON, M. LAFONTAN & P. VALET. A Simple and Highly Sensitive Radioenzymatic Assay for Lysophosphatidic acid Quantification. J. Lipid Res., 41: 1947-1951, 2000.

1999 (main publications)

C. PAGES, P. VALET, O. JEANNETON, A. ZAKAROFF-GIRARD, P. BARBE, M. RECORD, C. WOLF, F. CHEVY, M. LAFONTAN & J.S. SAULNIER-BLACHE. Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes: a paracrine signal for preadipocyte growth. Lipids34: S79, 1999.

C. PAGES, A. REY, M. LAFONTAN, P. VALET & j.S. SAULNIER-BLACHE. Ca++-independent phospholipase A2 (iPLA2) is required for alpha2-adrenergic-induced preadipocyte spreading. Biochem. Biophys. Res. Com.265: 572-576, 1999.

1998 (main publications)

P. VALET, C. PAGES, O. JEANNETON, D. DAVIAUD, P. BARBE, M. RECORD, j.S. SAULNIER-BLACHE & M. LAFONTAN. Alpha2-adrenergic receptor-mediated release of lysophosphatidic by adipocytes: a paracrine signal for preadipocyte growth.J. Clin. Invest.101: 1431-1438, 1998.

S. BETUING, D. DAVIAUD, C. PAGES, E. BONNARD, P. VALET, M. LAFONTAN & J.S. SAULNIER-BLACHE. G-independent coupling of alpha2-adrenergic receptor to p21rhoA in preadipocytes. J. Biol. Chem. 273: 15804-15810, 1998.