Fig. S1 Electron Microscopic Observations of Phagocytotic Activity of Sertoli Cells

Fig. S1 Electron microscopic observations of phagocytotic activity of Sertoli cells

(A) Electron microscopic observation of irradiated wild-type testis showing that apoptotic cells (arrowheads in A) are phagocytosed by enlarged Sertoli cells. (B) Enlarged view of the boxed area in (A) where apoptotic cells are phagocytosed (arrowheads show cell remnants in B). (C) Electron microscopic observation of irradiated p53 (-/-) testis and (D) enlarged view of the boxed area in C. (E) Another section of irradiated p53(-/-) testis showing that apoptotic cells (arrowheads in C, D and E) are phagocytosed in enlarged Sertoli cells. (F) Apoptotic testis-ova, supposed not to be phagocytosed by Sertoli cells (arrowhead in F), were often observed in a cyst of spermatozoa. Scale bars represent 5 µm.

Table. S1 The number of spermatocytes in non-irradiated and irradiated p53(-/-) testes

1