Examining the Prevalence Rates of Preexisting Maternal Medical Conditions and Pregnancy Complications by Source: Evidence to Inform Maternal and Child Research

Maternal and Child Health Journal

Authors:

Candace A. Robledo () 1,

Edwina H. Yeung () 1

Pauline Mendola () 1

Rajeshwari Sundaram () 2

Nansi S. Boghossian () 1

Erin M. Bell () 3, 4

Charlotte Druschel () 4, 5

Author affiliations:

1 Epidemiology Branch, Division of Intramural Population Health Research (DIPHR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH)

2 Bioinformatics Branch, DIPHR, NICHD, NIH

3Department of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York

4Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, State University of New York

5 Congenital Malformations Registry, New York State Department of Health (Charlotte Druschel).

Corresponding Author:

Dr. Edwina Yeung

6100 Executive Blvd, Room 7B03

Rockville, MD 20852

Office (301) 435-6921

FAX (301) 402-2084

Supplementary Table 1: List of ICD-9 Codes and Questionnaire Responses Used to Identify Pregnancy Complications using Maternal Report and Hospital Discharge Data

ICD-9 Codes / Description of Questionnaire Responsesa
Diabetes / 648.01, 250.x, 362.01 / Diabetes mellitus (high blood sugar) requiring insulin
Diabetes mellitus (high blood sugar) not requiring insulin
Chronic Hypertension / 401.1, 642.0, 642.2, 642.71 / High blood pressure (hypertension, not associated with pregnancy)
Gestational Diabetes / 648.8 / Gestational diabetes (high blood sugar that came on during this pregnancy)
Pregnancy-Related Hypertensive Disorders / 642.3, 642.4, 642.5, 642.6, 642.9 / Gestational hypertension (high blood pressure that came on during this pregnancy)
Pre-eclampsia or Toxemia (high blood pressure accompanied by protein in your urine)
Premature Rupture of Membranes / 658.1 / Preterm rupture of the membranes (breaking of amniotic sac before labor began)
Placental Abruption / 642.21, / Abruptio placenta (placenta lining separated from uterine wall)

a For pre-existing conditions mothers were asked “Has a doctor or health care provider ever diagnosed you with any of the following medical conditions? If so, please indicate if the condition was untreated, treated with medication, or treated with surgery.” For pregnancy-related conditions, women were asked, “Were you diagnosed by a doctor or health provider with any of the following medical conditions during this pregnancy?”

Supplementary Table 2: Number and % of preexisting maternal medical conditions and pregnancy complications by data source for outcomes identified by any two or only one data source, Upstate KIDS, 2008-2010

Any 2 Sources n (%) / Only 1 Source n (%)
n / SPARCS + MR / SPARCS+ BC / BC+MR / n / MR / SPARCS / BC
Gestational Diabetes / 130 / 60 (46) / 40 (31) / 30 (23) / 128 / 69 (54) / 17 (13) / 42 (33)
Diabetes / 19 / 14 (74) / 2 (10) / 3 (16) / 106 / 79 (75) / 13 (12) / 14 (13)
Pregnancy-Related Hypertensive Disorders / 257 / 139 (54) / 37 (14) / 81 (32) / 310 / 184 (60) / 94 (30) / 32 (10)
Chronic Hypertension / 57 / 33 (58) / 11 (19) / 13 (23) / 173 / 105 (61) / 42 (24) / 26 (15)
Placental Abruption / 24 / 9 (38) / 8 (33) / 7 (29) / 52 / 28 (54) / 21 (40) / 3 (6)
Premature Rupture of Membranes / 191 / 36 (19) / 98 (51) / 57 (30) / 342 / 83 (24) / 99 (29) / 160 (47)

MR = maternal report

BC = New York State Birth Certificate

SPARCS = Statewide Planning and Research Cooperative System