Examination on the test control of Bioorganic Chemistry
For the 1 st year students of medical faculty
1. Classification and nomenclature of organic
compounds
1. Pyrrole is a compound:
1. acyclic;
2. carbocyclic;
3. Heterocyclic, and aromatic;
4. saturated;
2. 2-Isopropyl-5-methylcyclohexanol on carbon skeletal structure of the compound is:
1. carbocyclic;
2. heterocyclic;
3 unsaturated and acyclic.;
4. aromatic;
3. 1,2,3-propanetriol is the compound of:
1. heterofunctional;
2. aromatic;
3. unsaturated;
4. polyfunctional;
4. According to functional groups benzocaine (ethyl p-aminobenzoate) is:
1. amid;
2. ester and amine;
3. ketone;
4. ether.
5. According to functional groups norepinephrine (2-amino-1- [3 ', 4'-dihydroxyphenyl] ethanol) is:
1. nitrile;
2. Alcohol, phenol;
3. Acid
4. amid;
6. According to functional groups 4 - hydroxy - 3 - ethoxybenzaldehyde is:
1. phenol, aldehyde, ether,
2. acid, Na+;
3.ester;
4. alcohol.
7. How many functional groups have 2 - hydroxy - 4 – methyl benzoic acid?
1. 1;
2. 2;
3. 3;
4. 4;
8. Compound phenylethylketone by the IUPAC nomenclature called:
1. benzoic acid methyl ester-1;
2. phenylpropylketone-3;
3. 1-phenyl-1-propanone;
4. benzyl ethyl ketone
9. By the UIPAC nomenclature the following compound is:
1. 3 -carboxy 3 – hydroxy pentane dioic acid;
2. 3 - hydroxy - 3 – formyl pentanedioic acid;
3. citric acid;
4. 3 – oxo pentantrioic acid;
10. By the UPAC nomenclature the following compound is;
1. 2 – formylbutandicarbonoic acid
2. 2 - oxoetanedioic acid;
3. 2- oxobutanoic acid;
4. 2 – oxobutanedioic-1,4 acid
2. Electronic Structure of Organic Compounds
11. There is no sp2- hybrid atoms in molecule of:
1. acetic acid
2. propanoic acid;
3. butane;
4. ethene
12. Pyrrole’s heteroatom has:
1. Aniline, ethanol;
2. ethanol;
3. phenol;
4. benzalydegid;
13. π-π – conjugation has the structure:
1. pentadiene - 1.3
2. pentadiene - 1.4
3. Butanoic acid;
4. propanoic acid.
14. p-π - conjugate has the structure:
1. acetic acid;
2. 2-propenal
3. ethylene glycol;
4. pyridine;
15. Aromatic compounds are:
1. cyclohexane;
2. cyclooctatetraene;
3. naphthalene;
4. butadiene
16. the following compounds are not aromatic:
1. pyridine;
2. cyclohexene-1;
3. anthracene;
4. furan.
17. In the functional group has a negative mesomeric effect in the compound of:
1. ethanol;
2. glycerol;
3. acetone;
4. butyen 2-al-1;
18. In the functional group has a negative inductive effect only in compound of:
1. phenol;
2. Acetic acid;
3. methylphenylketone;
4. ethanedioic acid;
19. All are electron withdrawing functional groups in the compounds:
1. 2-aminoethanol-1;
2. 2-hydroxybenzoic acid;
3. 4-aminobenzoyl sulfonic acid.
4. 4-hydroxy-3-methoxybenzaldehyde;
20. In the given compound electron donor functional groups are:
1. Amine group;
2. hydroxyl group of the alcohol;
3 phenolic hydroxyl groups;
4. benzene ring and the amino group;
3. Spatial structure of organic compounds.
21. Newman projection formula is written to show the differences of:
1. chemical structure of the compounds;
2. conformations and configuration of the molecule;
3. structural isomers;
4. geometric structure;
22. Energy of propanol-1 in the anti-conformation is lessthan gauche conformation, because in the anti-conformation:
1. less angular tension;
2. configuration has changed;
3. decreased Van der Waals repulsion;
4. was less torsional stress;
23. Energy of 2-chlorobutane in the eclipsed conformation more than gauche because in the eclipsed conformation:
1. The other configuration of the molecule;
2. The greater torsional stress;
3. increased Van der Waals repulsion.
4. the molecule another electronic structure;
24. The conformations of 1-chloropropane with a torsion angle of 60˚ and 300˚ are degenerate, because in these conformations the molecule have:
1. same configuration;
2. same chemical structure;
3. different conformational structure;
4. same torsion, Van der Waals and angular stresses;
25. The molecule 1,2 - dimethylcyclohexane has the maximum amount of energy, if:
1. Both methyl substituents in the equatorial bonds;
2. Both methyl substituents in the axial connections;
3. One of the two substituents on the axial connection;
4. The one of the two substituents on the equatorial bond;
26. The chiral molecule is:
1. glycine (2-aminoetanoic acid);
2. serine, (2-amino-3-hydroxypropanoic acid);
3. aminoethanol;
4. 1-butanol;
27. The chiral molecule is:
1. D - глюкоза;
2. glycerol;
3. 2 - aminoethanol;
4. 2-hydroxypronane;
28. The racemate can have a specific angle of rotation of plane polarized light at 25 ° C:
1. + 5,2˚;
2. 0,0˚;
3. -8,3˚;
4. -5,2˚;
29. 2-aminopropanoic acid has the following stereoisomers:
1. 1;
2. 2;
3. 3;
4. 4;
30. 2, 3, 4-trihydroxybutanoic acid corresponds to the following stereoisomers:
1. 6;
2. 2;
3. 9;
4. 4;
4. The acid-base properties of organic
compounds.
31. Show the order of acidity increase for the following compounds:
1.1,2-ethanediol>ethanol>4-nitrophenol>phenol
2.1,2-ethanediol<ethanol<4-nitrophenol<phenol
3.ethanol<1,2-ethanediol<phenol<4-nitrophenol
4.4-nitrophenol<phenol <1,2-ethanediol<ethanol
32. The acidic reaction centers are functional groups:
1. esters;
2. ketones;
3. Sulifonic acids;
4. ethers.
33. The main reaction centers are:
-1. +2. -3. +4. +5.
1. H+-1
2. –O-+2
I
3.-N--3
I
4. =O+4
34. The basic reaction site on the oxygen atom has in:
1. amines;
2. ketones, anhydride;
3. nitrile;
4. Halogenated hydrocarbons;
35. electrophilic particles are:
1.H
2.H-
3.H+
4.Br-
36. nucleophiles are:
1.H+
2.NH4+
3.OH-
4.Na+
37. The strongest basic center of the nicotine molecule is:
1. π-electron system of six-membered ring;
2. sp3-Hybrid nitrogen atom;
3. sp2-Hybrid nitrogen atom;
4. nitrogen atom to the pyridine structure;
38. The strongest acid center of molecule hydroxyproline (4-hydroxypyrrolidine-2-carboxylic acid) is:
1. OH- group consisting of carboxylic acid functional groups;
2. hydroxyl group with sp3-hybrid oxygen;
3. N-H acidic center;
4. OH group bonded directly to the heterocycle;
39. The most strong acidic properties of the compound shown in:
1. acetic acid;
2. propanoic acid;
3. 2-methylpropanoic acid;
4. 2,2,2-trichloroethanoic acid;
40. The weakest acid is:
1. ethanamine;
2. ethanol;
3. phenol;
4. ethanoic acid;
41. The strongest base is:
1. 2-aminoethanol;
2. ethanamine;
3. methylamine;
4. dimethylamine;
5. The mechanism of reactions in organic chemistry.
Reactivity of aliphatic and
aromatic hydrocarbons.
42. Homolytic cleavage of chemical bonds characteristic of the following compounds:
1. HCl;
2. Cl2, CH4;
3. Na+;
4. NaOH;
43. Heterolytic cleavage of chemical bonds is possible for the following compounds:
1. 2-chlorpropane;
2. ethane;
3. Br2;
4. benzene;
44. The nucleophilic reagents include:
1. Na+
2. C3H7NH2, OH;
3. Ammonium ion;
4. CH4;
45. Electrophilic reagents are:
1. NH3;
2 Br+, cation nitro;
3. C2H5OH;
4.ethanal.
46. As a electrophilic substrate can serve the following compounds:
1. ethanoic acid;
2. propene;
3. methanamine;
4. Hydrochloric acid;
47. The most stable among the carbocations is presented:
1.
2.
3.
4.
48. Among the most stable free radical is:
1.
2.
3.
4.
49. Alkane characterized by the following reaction:
1. AE;
2. AN;
3. SN;
4. SR;
50. The following conditions for the reaction of chlorination of butane are needed:
1. room temperature;
2. exposure to ultraviolet radiation (hn);
3. cooling;
4. catalyst FeCl3;
51. A major product of reaction (equimolecular ratio of mixture) of 2-methylpentane with bromine (when exposed to ultraviolet radiation) is:
1. 1-bromo-2-methylpentane;
2. 2-bromo-2-methylpentane;
3. 1,2-dibromo-2-methylpentane;
4 3-bromo-2-methylpentane;
52. The chlorination reaction of following compounds proceeds by a mechanism of radical substitution when exposed ultraviolet radiation:
1. cyclohexane;
2. benzene;
3. acetylene;
4. 1,3-butadiene
53. The characteristic reaction of alkenes is proceeding following mechanisms:
1. AE;
2. AN;
3. SE;
4. SN;
54. To carry out the reaction of cyclohexene with bromine need to create the following conditions:
1. heating above 100forC;
2. The special conditions are required;
3. рН <7;
4. It does not require special conditions.
55. The product of the reaction of 1-butene and HBr is:
1. 1 brombutan;
2. 2 brombutan;
3. butane;
4. 1,3-butadiene;
56.For propene hydration reaction is necessary to establish the following conditions:
1. anhydrous conditions;
2. The ultraviolet radiation;
3. acid catalyst;
4. catalyst FeCl3;
57. The product of the reaction of hydration of 2-propenal is:
1. 2-hydroxypropanal;
2. propanoic acid;
3. acetal;
4. 3-hydroxypropanal;
58. The product of the hydration of fumaric (butenedioic acid) in vivo is:
1. citric acid;
2. malic acid;
3. 2-hydroxybutanoic acid;
4. 2,3-dihydroxybutanedioic acid;
59. The product of hydration reaction of aconitoic (3-carboxypentyl-2-diovoy) acid, flowing through Markovnikov rule (in vivo) is:
1. isocitric acid;
2. 3-hydroxy-3-carboxypentanedioic acid;
3. acetoacetic acid;
4. 2-hydroxy-3-carboxypentanedioic acid.
60. Characteristic reaction for Benzene proceeds by following mechanisms:
1. AN;
2. AE;
3. SN;
4. SE;
61. To conduct methylation reaction of benzene are needed the following conditions:
1. acid catalyst;
2. concentrated alkali(NaOH, KOH);
3. catalyst FeCl3.
4. ultraviolet radiation;
62. The product of bromination of phenol is:
1. 2-bromophenol;
2. 3-bromophenol;
3. 2,4,6 tribromphenol;
4. 3,3-dibromophenol;
63. Product of mononitration of benzaldehyde is:
1. 2-nitrobenzaldehyde;
2. 3-nitrobenzaldehyde;
3. 4-nitrobenzaldehyde;
4. 3,3-dinitrobenzaldegid;
64. Product of monomethylation of benzoic acid is:
1. 2- metilbenzoic acid;
2. 3- metilbenzoic acid;
3. 4-metilbenzoic acid;
4. 2,4,6-trimetilbenzoic acid;
6. Hydroxy hydrocarbons
and their thio analogues.
Ether, a sulfide.
65. Ethyl alcohol (ethanol) is:
1. secondary;
2. Monohydric, primary;
3. polyhydric;
4. unsaturated.
66. tert-butanol (2-methylpropanol-2) is:
1. Monatomic, tertiary;
2. polyhydric;
3. primary;
4. secondary;
67. The allylic alcohol (2-propen-1-ol) is:
1. primary;
2. secondary;
3. unsaturated;
4. polyhydric;
68. Glycerol is:
1. monohydric alcohol;
2. dihydric phenol;
3. polyhydric alcohol;
4. tertiary alcohol;
69. Hydroquinone corresponds systematic name:
1. phenylmethanol;
2. cyclohexanol;
3. 2-isopropyl-5-metiltsiklogeksanol-1;
4. 1,4-dihydroxybenzene
70. Diethyl ether corresponds to the systematic name:
1. ethanethiol;
2. 2,3-dimercaptopropanol-1;
3. ethoxyethane;
4. 1,2,3-trihydroxypropane;
71. To methylthioethane relevant information is:
1. a functional derivative of thiols, easily oxidized by a hetero atom;
2. applies to phosphates and unsaturated
3. easily soluble in water and has isomers
4. exhibits acidic properties
72. The secondary alcohols include:
1. 3-pentanol, cyclohexanol;
2. 1-propanol, 1- pentanol;
3. 2-methylbutanol-2, 2-methylpentanol-2
4. benzyl alcohol;
73. The tertiary alcohols are:
1. 1,2,3-trihydroxy benzene;
2. 3-methyl pentanol-3;
3. cyclopentanol;
4. benzyl alcohol.
74. The primary alcohols are:
1. cyclohexanol;
2. benzyl alcohol;
3. Isopropyl alcohol;
4. phenol;
75. The oxygen atoms are sp3–hybridized in:
1. Ethylene alcohol;
2. 2,3-dimercaptopropanol-1;
3. propanal-1;
4. vinyl alcohol;
76. The oxygen atom is SP2-hybrid composed of:
1. b-naphthol, timola, anizola;
2.propargyl alcohol;
3. diethyl ether
4. ethylene glycol.
77. Only pyrrole oxygen atoms included in the composition:
1. ortho-cresol;
2. picric acid;
3. mint;
4. ethoxyethane;
78. The molecule of 1-propanol present reaction centers:
+1. OH acid, main, electrophilic;
2. SH-acid;
3. nucleophilic;
4. CH-acidic.
79. The molecule β-naphthol reaction centers are present:
1. OH acid;
2. SH-acid;
3. electrophilic;
4. CH-acidic.
80. Ethanethiol molecule present reaction centers:
1. OH-acidic;
2. SH-acid, nucleophilic;
3. electrophilic;
4.CH-acidic;
81. Nucleophilic properties hetero increase in the number of connections:
1. 2-methylphenol, 2-methylpropanol-1 → metiltiometan;
2. эtoksipropan → 2-isopropyl-5-methylphenol → thiophenol;
3. metiltiobenzol metiletilsulfid → 1,4-dihydroxybenzene;
4. dioxane-1,4 → → Cyclohexanone эtoksibenzol;
82. In the center of the nucleophilic reactions of alcohols:
1. with hydrogen halides;
2. with bases;
3. The functional derivatives of carboxylic acids;
4. The alkylation, in the presence of concentrated H2SO4, to~ 140forC;
83. The main properties are most pronounced at the next of the following compounds:
1. menthol (2-isopropyl-5-metiltsiklogesanol);
2. thymol (2-isopropyl-5-methylphenol);
3. ethyl propyl ether (ethoxypropane);
4. myetilizobutilsulifid (1 myetiltio myetilpropan 2);
84. OH-acidic properties increase from left to right in a row:
1. phenol benzyl alcohol → → ethanol;
2. glycerin → → izopropilovыy alcohol resorcinol;
3. pyrogallol → → ethylene glycol tert-butyl alcohol;
4. Methanol → → hydroquinone glycerine;
85. In the main center of diethyl ether are reactions:
1. Acid;
2. with bases;
3. with electrophilic substrates;
4. recovery;
86. Dissolve copper hydroxide (II) to form a blue complex alcohols:
1. ethanol;
2. benzyl alcohol;
3. ethylene glycol;
4. 2-isopropyl-5-methylphenol;
87. Dissolution of copper hydroxide precipitate (II) to form a blue complex salt solution is to qualitative reaction:
1. unsaturated hydrocarbons;
2. Halogenated hydrocarbons;
3. monohydric alcohols;
4. vicinal polyhydric alcohols;
88. Phenols dissolve in:
1. alkalis;
2. a saturated solution of NaCl;
3. acids;
4. saturated solution of NaHCO3;
89. According to the electrophilic center of the reactions of alcohols:
1. AN;
2. SN1;
3. AN-E;
4. AE.
90. In the nucleophilic substitution reactions (the S N) alcohol molecule can act as:
1. nucleophilic reagentelectrophilic center;
2. electrophilic reagent;
3. radical agent;
4. The substrate with a nucleophilic center.
91. The reaction of bimolecular substitution (the S N2) is most common for alcohol:
1. 3-hexanol;
2.2-methylcyclohexanol-1;
3. methanol;
4. 2-2-methylpropanol;
92. The unimolecular substitution reaction (SN1) takes place at a maximum speed of alcohols:
1. neo-hexyl;
2. propyl;
3.tert-butyl;
4. benzyl;
93. Stereospecificity are the reactions occurring at the chiral centers of electrophilic substrates alcohols according to the mechanism:
1. SN1;
2. SN2;
3. AN;
4. AN-E;
94. Acid catalyzed reactions of S inN, flowing through electrophilic center alcohols leads to:
1. increase the solubility of alcohols;
2. increase the unsolubility of alcohols;
3. stabilization nucleofuge (leaving group);
4. Formation carboanions
95. Elimination reactions occur at a maximum speed among the listed at:
1. neo ethyl alcohol;
2. Butanol-1;
3. 2-butanol;
4.tert-butyl alcohol;
96. Zaitsev rule runs elimination (E) of the alcohols:
1. 2-propanol;
2. methylpropanol-2-2;
3. 1-butanol;
4. 2-butanol, 2-methylbutanol-2.
97. With the highest rate of reaction occurs SEin the compound:
1. benzene;
2. naphthalene;
3. phenol;
4. chlorobenzene;
98. The reaction of O-acetylation of phenol leads to:
1. 2'-hydroxyacetophenone;
2. 4'-hydroxyacetophenone;
3. phenylacetate;
4. 2`,4`-digidroksiatsetofenona;
7. Reactivity of aldehydes and ketones.
99. The reaction of aldehydes centers are:
1. electrophilic, basic, α-CH-acidic;
2. Only nucleophilic and basic;
3. Only nucleophilic, base and acid;
4. Only electrophilic and nucleophilic;
100. aromatic aldehydes, oxo which is directly linked to a benzene ring, there is no next reaction center:
1. electrophilic;
2. electrophilic and basic;
3. are CH-acidic and basic;
4. are -СН-acid;
101. Cyclohexanone is:
1. aromatic aldehyde;
2. carbocyclic ketone.
3. The heterocyclic ketone;
4. aliphatic aldehyde;
102. For oxo compounds characterized by the following reaction:
1. AN, AN-E, reduction and oxidation.
2. The nucleophilic substitution;
3. The electrophilicsubstitution;
4. The reaction involving a-CH-acidic center;
103. The reactivity of oxo compounds to the AN reactions increases:
1. of methanal to ethanal;
2. acetone to propanal;
3. from ethanal to butanal;
4. pentanona for acetone;
104. The most reactive compound in the reactions ANis:
1. ethanal;
2. chloral;
3. pentanone;
4. 3-metilbutanaly;
105. The role of acid catalysis reactions ANis:
1. The decreased activity of the main center;
2. The elimination of spatial barriers;
3. The increase in the activity of the electrophilic center;
4. Change the configuration of the molecule;
106. Product of addition of water to the aldehyde is:
1. ketone;
2. The ester;
3. vicinal alcohol;
4. geminal dihydric alcohol;
107. The final product of the reaction between ethanal and methanol in an acidic environment is:
1. metiletanoat;
2. etilmetanoat;
3. 1,1-dimethoxyethane;;
4. 1,1-diethoxymethane;
108. The following end-products formed in the hydrolysis of 1,1-dietoxybutana:
1. ethanol and butanoic acid;
2-butanol and acetic acid;
3. ethanol and butanol;
4. ethanol and butanaly.
109. For the synthesis of 1,1-dimethoxyethane is used the following compounds:
1. methyl alcoholand butanaly;
2. metanaly and butanol;
3. butanone and methanol;
4. formic acid and butanol;
110. Reactions of oxo compounds with amines proceed by the mechanism:
1. AN;
2. SN;
3. E;
4. AN-E;
111. The reaction of oxo compounds with amines and their derivatives are used:
1. quantitative analysis;
2. for synthetic compounds;
3. in the preparation of nitric acid;
4 for the isolation of aldehydes and ketones from the reaction mixtures;
112. The reactions in the hydrocarbon radical for a-CH-acidic center may oxo compounds for the following:
1. benzaldehyde;
2. Ethanal, acetone;
3. 2,2-dimetilbutanaly;
4 . 2 etilpentanal.
113. Reactions of substitution of hydrogen with halogen in the α-CH-acidic center are impossible for these oxo compounds:
1. propanaly;
2-butanone;
3. 2,2-dimetilpropanalyand diphenyl ketone;
4.2,2-dimetilbutanaly;
114. The haloform reaction is possible for the following compounds:
1. acetone, ethanal;
2. prohanole;
3. benzalydegid;
4. formaldehyde;
115. The primary alcohols can be prepared by reduction of oxo compounds following:
1. acetone;
2. propanaly;
3. benzaldehyde;
4 methyl propyl;
116. 3-methylbutanol-2 can be prepared by reduction of a compound:
1. 3-metilbutanaly;
2. 3-metilpentanal;
3. 3-methylbutanol-2;
4. 2-methylbutanol-3;
117. Hydroxide copper (II) in an alkaline solution under heating does not oxidize oxo compounds following:
1. formaldehyde;
2. propanaly;
3. Acetone, 3-methyl-pentanone-2;;
4. 2-methylbutanol-3;
118. The oxidation of benzaldehyde formed Tollens reagent:
1. The benzyl alcohol and red-orange precipitate;
2. benzoic acid and "silver mirror" or dark precipitate;
3. benzyl alcohol and the "silver mirror";
4. benzene and brick-red precipitate;
119. As a result of disproportionation of formaldehyde formed:
1. methanol and water;
2. methanol and formic acid;
3. The formic acid and water;
4. The methanol and hydrogen;
8. Reactivity carboxylic acids and functional derivatives.
120. According to the number of carboxyl groups of the carboxylic acids are classified into:
1. Monocarboxylic, dicarboxylic, tricarboxylic;
2. Tricarboxylic, aliphatic, aromatic;;
3. aliphatic, aromatic, monocarboxylic;;
4. aliphatic, oxalic (ethanediotic) acid ;
121. According to the nature of the carbon skeleton carboxylic acids are classified into:
1. monocarboxylic;
2. dicarboxylic;
3. tricarboxylic;
4. aliphatic, aromatic;
122. Aliphatic monocarboxylic acids are:
1. ethane;
2. acetic acid;
3. benzoic;
4. Butane chloride;
123. Aromatic monocarboxylic acid is:
1. propane;
2. benzoic;
3. oxalic (ethanediotic) acid;;
4. isophthalic (1,3-benzenedicarboxylic) acid;
124. Aliphatic dicarboxylic acids are:
1. Oil (butane) acid;
2. oxalic (ethanediotic) acid;
3. malonic anhydride;
4. isophthalic (1,3-benzenedicarboxylic) acid;
125. The functional derivatives of carboxylic acids are:
1. ethanoic acid;
2. etanoilhlorid;
3. ethyl chloride;
4. acetic acid;
126. The structure corresponds to a carboxyl group:
1. SP2-Hybrid state of carbon and oxygen atoms;
2. SP2-Hybrid state carbon atom and one oxygen atom, SP3hybridization second oxygen atom;
3. The six-center dual system;
4. The absence of the dual system;
127. The carboxyl group in the molecules responsible for the presence of aliphatic carboxylic acids majority reaction centers:
1. OH acid;
2. NH-acid;
3. -NH-acidic;
4. nucleophilic;
128. The acidic properties of carboxylic acids occur at the reaction center:
1. OH acid;
2. NH-acid;
3.SN-acid;
4. electrophilic;
129. When dissolved in water carboxylic acid:
1. рН <7;
2. Wednesday neutral;
3. pH> 7;
4. alkaline condition;
130. Adding sodium hydroxide solution at room temperature:
1. methyl benzoate;
2. Benzoic acid;
3. aniline;
4. butanic acids;
131. A number of acids: acetic → malonic (propanedioic) → oxalic acid (ethanedioic) corresponds to the sequence of the pKafor the first dissociation stage:
1. 1,2 → 2,86 → 4,75;
2. 1,2 → 4,75 → 2,86;
3. 2,86 → 1,2 → 4,75;
4. 4,75 → 2,86 → 1,2;
132. Carboxylate anion stability due to the presence therein:
1. p, p- conjugation;
2. p, π-conjugation;
3. full delocalization of the negative charge;
4. localization of negative charge on one of the atoms;
133. Functional derivatives of carboxylic acids formed by the reactions of:
1. electrophilic conjugation (AE);
2. nucleophilic conjugation (AN);
3. acylation;
4. electrophilic substitution (SE);
134. Functional derivatives of carboxylic acids formed by the reaction:
1. OH-acids;
2. CH-acids;
3. electrophilic;
4. nucleophilic;
135. By reaction propanoic acid with ethanol in acidic medium is formed:
1. propanoic acid ethyl ester;
2. propanoic acid anhydride;
3. propanamide;
4. propanoylchloride.
136. An ester formed by the reaction of acetic acid with a reagent:
1. Alcohol /НÅ, to;
2, alkylthiol / HÅ, to;
3. NH3/to;
4. SOCl2/to;
137. One of the products butanoic acid reaction with ammonia prolonged heating is:
1. butanoate;
2. butanoicacid amide;
3. Butanoyl chloride;
4. butanbromide;
138. The product of the reaction of acetic acid under heating in the presence of P2O5is:
1. ethyl ethanoate;
2. acetic acid anhydride;
3. acetamide;
4. etanoilhlorid;
139. The acid chloride formed by reaction of nicotine (3-pyridinecarboxylic acid) reagent:
1.2H5OH / HÅ, to;
2. PCl5/to;
3. NH3/to;
4. pH> 7;
140. Kordiamin - N, N-Diethyl-nicotinic (3-pyridinecarboxylic acid) formed by reaction with the acid chloride of nicotinic acid reagent:
1. The ethyl alcohol;
2. diethylamine;
3. nicotinic acid;
4. ammonia;
141. The hydrolysis of carboxylic acid functional derivatives takes place at the reaction center:
1. carbon atom the functional group;
2. are 2-CH-acids;
3. NH-acids;
4. nucleophilic.
142. The reaction of acid hydrolysis is not to form carboxylic acids:
1. Acilgalogenidy;
2. anhydrides;
3. ethers;
4. esters;
143. The acidic hydrolysis reaction to give the corresponding carboxylic acids come:
1. ethyl chloride;
2. ethanoilhlorid;
3. anhydrides;
4. ethoxypropane.
144. The acylating ability of carboxylic acids and their functional derivatives is defined by:
1. The value of the effective positive charge in the nucleophilic center;
2. The nature and effectiveness of electronic effect of substituents on electrophilic center;
3. The nature and effectiveness of electronic influence of substituents on the a-CH-acidic center;
4. The polarization due to the a-CH-acidic center.
145. The acylating maximum capacity has:
1. ethyl ethanoate;
2. etanoilhlorid;
3. ethanoic acid;
4. etanamid;
146. The rate of hydrolysis at the maximum:
1. etanamida;
2. propiletanoata;
3. ethanoic acid amide;
4. acetic anhydride;
147. Easy decarboxylated by heating acid:
1. acetic (ethanoic);
2. oxalic (ethanediotic)
3. Malonoc acid;
4. propane acid;
148. The action of bromine on the propanoic acid in the presence of red phosphorus as follows:
1. brompropan;
2. 2-bromopropanoic acid;
3. propanamide
4. propilpropanoat;