Duke CFAR Small Grant Program Application Checklist

Grant Title Enter text here. Box will expand to fit contents.

Submission Date

Applicant information

Applicant Department/Division

Co-Applicant if applicableDepartment/Division

International Project Location

Budget

BFR#

Departmental Grants Manager Contact

Please indicate your faculty rank below

Post-doc or Fellow with Faculty offer (if funded, requires a CFAR Mentoring Plan)

Assistant Professor (if funded, requires a CFAR Mentoring Plan)

Associateor Full Professor

Previous CFAR Funding?

YesNo

If yes, please answer the following questions about the previous award:

Title

Date of Award

Publications resulting from Award

Funding resulting from Award

How is this proposed research different from the previous award?

Grant Review Training

The Duke CFAR Developmental Core provides CFAR members exposure to the grant review process by allowing CFARfaculty and postdoctoral trainees to observe the small grant review process to learn the types of discussions that develop during a grant review meeting. At this time, those observing the small grant review are permitted to observe the discussion but they are not permitted access to the small grants or the reviewer’s written critiques.

Would you be willing to allow your CFAR Developmental Core small grant application and summary statement to be used in future grant review training sessions?

Yes

No

Self-reporting of CFAR user Category for the NIH

Required by the NIH

Indicate the user category that applies, below.

*All CFAR users will fall into one of these four categories.

1-NIH AIDS PI Individuals who have ever been the PI on an R01 equivalent grant in HIV/AIDS (R01 equivalents include R01, R23, R29, R37 and, after 2008, DP2)

2-NIH PIs being brought into AIDS research: Individuals who are or have ever been the PI on an R01 equivalent grant, but never in HIV/AIDS

3-AIDS-research Pipeline: NIH “New Investigators,” An NIH definition that encompasses individuals who have received funding as a PI directly from NIH*, but not yet at the R01 equivalent level.

4-AIDS-research Pipeline: CFAR Users who have not yet received direct funding from NIH** as PI or Co-PI funding on any NIH grant mechanism.

**Individuals whose only NIH funding at the PI or PD level has come indirectly from NIH, for example via an NIH CFAR Administrative Supplement, fall into Category 4.

*Some CFAR users will also fall into one of these categories. Please check all that apply.

Developmental Core Special Emphasis. Recipients of Core B research funding, mentoring, and/or other services

Developmental Core Special Emphasis. Recipients of NIH CFAR administrative supplements

NIH Special Emphasis: Members of underrepresented groups in AIDS research. These include African-Americans, Hispanics, American Indians, Alaska natives, native Hawaiians, and Pacific Islanders

NIH Special Emphasis. Women

HIV/AIDS Priority Targeted Areas

High Priority Areas

Reducng Incidence of HIV/AIDS including: developing and testing promising vaccines, developing and testing microbicide and pre-exposure prophylaxis candidates and methods of delivery, especially those that mitigate adherence issues; and developing, testing, and implementing strategies to improve HIV testing and entry into prevention services.

Next generation of HIV therapies with better safety and ease of use including: developing and testing HIV treatments that are less toxic, longer acting, have fewer side effects and complications, and easier to take and adhere to than current regimens. Additionally, implementation research to ensure initiation of treatment as soon as diagnosis has been made, retention and engagement in these services, and achievement and maintenance of optimal prevention and treatment responses.

Research toward a cure including: developing novel approaches and strategies to identify and eliminate viral reservoirs that could lead toward a cure or lifelong remission of HIV infection, including studies of viral persistence, latency, reactivation, and eradication.

HIV-associated comorbidities, coinfections, and complications including: addressing the impact of HIV-associated comorbidities, including tuberculosis, malignancies; cardiovascular, neurological, and metabolic complications; and premature aging associated with long-term HIV disease and antiretroviral therapy.

Cross cutting areas: Basic research, health disparities, and training including:

Basic Research: understanding the basic biology of HIV transmission and pathogenesis; immune dysfunction and chronic inflammation; host microbiome and genetic determinants; and other fundamental issues that underpin the development of high priority HIV prevention, cure, co-morbidities, and treatment strategies.

Research to Reduce Health Disparities in the incidence of new HIV infections or in treatment outcomes of those living with HIV/AIDS.

Research Training of the workforce required to conduct High Priority HIV/AIDS or HIV/AIDS-related research.

Medium Priority Areas

The project examines a fundamental scientific question (or questions) that has a clear or potential link to HIV/AIDS;

The project includes people (or biological specimens from people) who are living with HIV, are HIV exposed, and/or are at elevated risk for HIV infection as part of a broader sample or as a comparative cohort;

The project addresses health and social issues that are clearly linked with HIV (transmission/acquisition, pathogenesis, morbidity and mortality, stigma) and examines them in the context of HIV (i.e., in populations or settings with high HIV prevalence or incidence), such as other infectious pathogens and diseases, non-infectious pathogens and diseases, substance use/addiction, and mental health disorders;

The project meaningfully includes HIV/AIDS (or SIV) outcomes/endpoints; or

The results of the project will advance HIV treatment or prevention and/or provide tools/techniques and/or capacity beneficial to HIV research (including training and infrastructure development).

Project Summary

type here

Plan for future funding

type here

Duplication of Funding

If a small grant is funded by the Duke CFAR and a similar proposal is funded by NIH during that same funding year, the applicant must meet with CFAR to either 1- make sure the research proposal from CFAR does not overlap with the NIH proposal or 2- return funds to CFAR or refuse funds from NIH.

CFAR Mentoring Plan

As a condition of award, Junior Faculty(i.e. Instructor, Assistant Professor)and Researchers new to HIV/AIDSare required to have a mentoring plan that includes a CFAR memberas a constituent. The CFAR member must be a Core Leader or an experienced researcher with a faculty rank of at least Associate Professor.

Career development resources available at Duke

Grant writing: Gopen Writing Seminars

Registration is on a first-come, first-served basis. Faculty are given priority. There are limited seats available for fellows, postdocs, students, and staff.

Path to Independence Program/K Club

  • The Path to Indepence is designed to help Assistant Professors secure NIH R01 or DOD funding.
  • The K Club is a program designed to help junior faculty prepare career development (K) grant applications

Grant writing resources (

Duke CFAR RFP Checklist December 2016cfar.duke.edu