Principal Investigator/Program Director (Last, first, middle): DURFEE, WILLIAM K.

BUDGET JUSTIFICATION

Systems Technology, Inc. budget

PERSONNEL:

T. Rosenthal (STI): Responsible for leading the technology team at STI. This team will implement the changes to STISIM Drive, will assemble, ship and install 3 new simulators, will implement new report generators and automatic data analysis routines, will provide technical support to all sites. Support beyond what is requested in the proposal for the level of effort required to complete the project will be provided by STI.

J. Wachtel (Consultant): Responsible for human factors aspects of project. See proposal Section I and consultants letter for details. ($10,000 Y1, $15,000 Y2)

B. Center (Consultant): Responsible for statistics and data analysis methods aspects of project. See proposal Section I and consultants letter for details. ($2,400 Y1, $3,600 Y2)

EQUIPMENT:

Three STISIM Drive simulators at $20,000 per simulator. Cost per simulator includes purchase cost of car buck from Advanced Therapy Products, all computer hardware, and cost of assembly by STI. Cost for installation and maintenance by STI appears under travel. Simulators will be placed at SKRS, CC and NRH. The simulator currently at SKRS will move to UMN for development purposes.

TRAVEL:

Project kick-off meeting in Minneapolis. Travel costs for Rosenthal (STI), Wachtel (Consultant) and Rosen (Nat'l Rehab Hosp) to travel to Mpls plus meeting costs for Mpls team members. Purpose of meeting is to review protocols and data collection procedures, train research staff, and plan project. ($5,500).

Travel cost for STI personnel to install and maintain simulators at three sites ($8,000 Y1, $4,500 Y2).

CONTRACTS:

University of Minnesota. See research institution budget and the second section of this budget justification for details. ($92,991 Y1, $83,376 Y2)

Sister Kenny Rehabilitation Services. See Section H and contracting letter for details. ($15,000 Y1, $15,000 Y2)

Courage Center. See Section H and contracting letter for details. ($10,000 Y1, $24,000 Y2)

National Rehabilitation Hospital. See Section H and contracting letter for details. ($10,000 Y1, $20,000 Y2)

Subject payments. $50/session for 60 sessions ($1,500 Y1, $6,000 Y2)

UFOV test instrument. One kit with 100 test credits ($1,000/kit) for each of the three clinical sites. ($3,000 Y1)

University of Minnesota budget

PERSONNEL:

W. DURFEE, Principal Investigator - Responsible for scientific and engineering direction of project. Responsible for overall project management. Will assist in the design of the scenarios and experiment protocols. Will lead project team meetings. Will oversee expenditures and effort levels. Will manage the creation of manuscripts and conference presentations to disseminate results. Will direct the graduate research assistant.

E. STERN, Co-investigator - Responsible for scientific direction of the clinical aspects of project. Will participate in the design of the experiments, including data analysis methods. Will help formulate detailed experiment protocols and will oversee clinical data collection procedures. Will assist in the supervision of the graduate research assistant.

TO BE NAMED, Research Assistant - Graduate student in mechanical or biomedical engineering. Will assist with all aspects of the project, including implementation of scenarios, protocol design, data collection and analysis, and reporting of results.

SUPPLIES:

SPSS - $150 (each year) - License for SPSS statistics package. University rate is $150/year. SPSS manuals - $200 (Y1). Desktop computer, laptop computer - $3,000 (Y1) - Pentium desktop PC for archiving data and running data analysis. Pentium laptop PC for real-time data collection during on-road tests. Data storage - $400 (each year) - Disks CD's and video tapes for data archiving. Data collection hardware - $5,000 (Y1) - Palm Pilots for portable data entry. Video camcorder for collecting driving event data. GPS unit for on-road tests. Sensors for brake event monitoring.

TRAVEL:

Presentation of results at a professional conference. Two participants each year. ($2,400 Y1, $2,472 Y2)

OTHER EXPENSES:

Preparation of manuscripts, page charges ($250 Y2)

***** BUDGET NUMBER JUSTIFICATIONS *****

Indirect Costs:

Year 1 - 55,583 x 48.50% = 26,957

Year 2 - 49,037 x 48.50% = 23,782

Total to apply IDC Rate to = Total Direct Costs - Backed Out Costs

104,620 = 125,628 - 21,008

Total Indirect Costs = 50,739

Total Costs = Total Direct Costs + IDC

176,367 = 125,628 + 50,739

Future years recurring costs have been calculated using a 3% inflation rate, unless noted otherwise in the item justification.

ACADEMIC Fringe Rates: CIVIL SERVICE Fringe Rates:

FY2003 - 33.10% 31.10%

FY2004 - 33.10% 31.10%

FY2005 - 33.10% 31.10%

GRADUATE/PROFESSIONAL TRAINING STUDENTS Fringe Rates:

Fringe varies by individual based on percent of time appointed and the number of credits.

 PHS 398/2590 (Rev. 05/01)Page 1Continuation Format Page

Principal Investigator/Program Director (Last, first, middle): DURFEE, WILLIAM K.

BIOGRAPHICAL SKETCH
Provide the following information for the key personnel in the order listed for Form Page 2.
Follow the sample format for each person. DO NOT EXCEED FOUR PAGES.
NAME
DURFEE, WILLIAM KEITH / POSITION TITLE
PROFESSOR
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / YEAR(s) / FIELD OF STUDY
Harvard University / A.B. / 1976 / Engng & Appl. Physics
Massachusetts Institute of Technology / M.S. / 1978 / Mechanical Engng
Massachusetts Institute of Technology / Ph.D. / 1985 / Mechanical Engng

A. Positions and Honors.

PROFESSIONAL EXPERIENCE

1976 - 1978 Harvard-MIT Rehabilitation Engineering Center: Project Engineer

1978 - 1985 MIT (Mechanical Engineering): Research Assistant

1985 - 1990 MIT (Mechanical Engineering): Assistant Professor

1990 - 1991 MIT (Mechanical Engineering): Associate Professor

1991 - 1993 MIT (Mechanical Engineering): Brit and Alex d'Arbeloff Associate Professor of Engineering Design

1993 - 2001 University of Minnesota (Mechanical Engineering): Associate Professor

2001 - present University of Minnesota (Mechanical Engineering): Professor and Director of Design Education.

Additional appointments to the Graduate Faculty in the Department of Biomedical Engineering, The Carlson

School of Management, The Program in Human Factors and the Program in Aging.

HONORS

1979 NIGMS: Biomedical Engineering Fellowship

1979 - 1981 NIH: National Research Service Award

1982 - 1984 Whitaker Foundation: Doctoral Fellowship

1986 - 1988 MIT: W. M. Keck Foundation Chair in Biomedical Engineering

1990 MIT: Graduate Student Council Teaching Award

1991 - 1993 MIT: Brit and Alex d'Arbeloff Chair in Engineering Design

1993 MIT: J.P. Den Hartog Distinguished Educator Award

1993 MIT: Graduate Student Council Teaching Award

1996 ASME: Curriculum Innovation Award

2000 University of Minnesota: George W. Taylor Distinguished Teaching Award

2000 Minnesota State Council on Disability: Educator of the Year Award

2001 University of Minnesota Morse Award for Outstanding Contributions to Undergraduate Education

GOVERNMENT SERVICE

1997-present: Chair NIH Special Emphasis Panel (ZRG1-SSS-5) for SBIR/STTR proposals on rehabilitation engineering.

B. Selected peer-reviewed publications (in chronological order).

* Durfee, W., Task-based control with an electrically stimulated antagonist muscle pair, IEEE Trans. Biomed. Eng., BME-36(3):309-321, 1989.

* Durfee, W. and K. MacLean, Methods for estimating isometric recruitment curves of electrically stimulated muscle, IEEE Trans. Biomed. Eng., BME-36(7):654-667, 1989.

* Durfee, W. and J. Hausdorff, Regulating knee joint position by combining electrical stimulation with a controllable friction brake, Annals of Biomedical Engineering, 18:575-596, 1990.

* Hausdorff, J. and W. Durfee, Open-loop position control of the knee joint using electrical stimulation of the quadriceps and hamstrings, Med. Biol. Eng. & Comp., 29:269-280, 1991.

* Durfee, W., T. Mariano, and J. Zahradnik, Simulator for evaluating shoulder motion as a command source for FES grasp systems, Arch. Phys. Med. Rehab., 72(13):1088-94, 1991.

* Durfee, W., Muscle model identification in neural prosthesis systems. In Neural Prostheses: Replacing Motor Function After Disease or Disability, Eds. R. Stein and H. Peckham, Oxford University Press, 1992.

* Durfee, W., Introduction to the special issue on practical functional electrical stimulation, Assistive Technology, 4(1):1-3, 1992.

* Durfee, W., Control of standing and gait using electrical stimulation: Influence of muscle model complexity on control strategy, Progress in Brain Research, 97:369-381, 1993.

* Durfee, W. and K. Palmer, Estimation of force-activation, force-length and force-velocity properties in isolated,

electrically stimulated muscle, IEEE Trans. Biomed. Eng., 41(3):205-216, 1994.

* Durfee, W. Control of prosthetic gait, Current Opinion in Neurobiology, 4(6):920-923, 1994.

* Karu, Z., W. Durfee and A. Barzilai, Reducing muscle fatigue in FES applications by stimulating with N-let pulse trains, IEEE Trans. Biomed. Eng., 42(8):809-817, 1995.

* Durfee, W. Designing smart machines: teaching mechatronics to mechanical engineers through a project-based, creative design course, Mechatronics, 5(7):775-785, 1995.

* Goldfarb, M. and W. Durfee, Design of a controlled-brake orthosis for FES-aided gait, IEEE Trans. Rehab. Eng., 4(1):13-24, 1996.

* Hoffer, J., R. Stein, M. Haugland, T. Sinkjaer, W. Durfee, A. Schwartz, G. Loeb and C. Kantor, Neural signals for command control and feedback in functional neuromuscular stimulation: A review, J. Rehab. Res. Develop., 33(2):145-157, 1996.

* Chesler, N. and W. Durfee, Surface EMG as a fatigue indicator during FES-induced isometric muscle contractions, J. Electromyogr. Kinesiol., 7(1):27-37, 1997.

* Durfee, W., C. Hendrix, P. Cheng, G. Varughese, Influence of haptic and visual displays on the estimation of virtual environment stiffness, Proceedings of the ASME Dynamic Systems and Control Division, DSC-Vol. 61, 139-144, 1997.

* Durfee, W. Electrical stimulation for restoration of function, Neurorehabilitation, 12(1):53-62, 1999.

* Hendrix, C, P. Cheng, W. Durfee, Relative influence of sensory cues in a multi-model virtual environment, Proceedings of the ASME Dynamic Systems and Control Division, DSC-Vol. 63, 1999.

* Durfee W., From idea to product. In Biomechanics and Neural Control of Movement, Eds. J. Winters and P. Crago, Springer-Verlag, 2000.

* Rainoldi, A., W. Durfee and R. Merletti., Twitch summation with double stimulation, Proceedings of the 7th Vienna International Workshop on Functional Electrical Stimulation, 106-109, 2001.

* Wachtel, J., Durfee, W.K., Rosenthal, T.J., Schold-Davis, E., and Stern, E.B. Evaluation of a Low-Cost, PC-Based Driving Simulator to Assess Persons with Cognitive Impairments Due to Brain Injury. Proceedings of the First International Driving Symposium on Human Factors in Driver Assessment, Training and Vehicle Design. Aspen, CO. pp.293-294., 2001

* Stern, EB, Wachtel, J, Durfee, WK, Rosenthal, TJ and Schold Davis, E, Low-Cost Simulation as a Tool to Assess the Driving Ability of Persons with Cognitive Impairments from Brain Injury. In P.T. McCabe (Ed.), Contemporary Ergonomics 2000, London: Taylor & Francis, in press, 2002.

C. Research Support

Optimal haptic controls using a configurable haptic interface

The purpose of this project is to examine the use of novel haptic interfaces in automotive control applications. A "super knob" with changeable haptic (feel) properties will be tested as a substitute for a car's secondary controls. The super knob will be tested on the STISIM Drive driving simulator using non-disabled human subjects. (Ongoing)

Virtual environments for product prototyping

The purpose of this project is to examine multi-sensory virtual environments for product prototyping. Single degree-of-freedom panel interfaces are emulated using virtual visual, audio and haptic displays. Psychophysical experiments are conducted to determine how the senses integrate to provide a sense of presence in the virtual environment. Additional experiments compare design decisions made in the virtual environment to those made in a real environment (Ongoing)

Modeling of electrically stimulated muscle

The purpose of this project is to model the mechanical response of muscle to electrical stimulation. The long range goal is to create improved methods for designing controllers for systems that restore function to paralyzed muscles through electrical stimulation. (Ongoing)

Doublet response of electrically stimulated muscle

Muscles stimulated with doublet responses take longer to fatigue under artificial stimulation. The purpose of this project is to understand the complete mechanical responses of muscle to doublet stimulation and to develop novel stimulation patterns that optimize fatigue properties. (Ongoing)

Hybrid system for FES-aided gait restoration

In this project, we explored the use of a custom orthosis, the controlled-brake orthosis, in combination with electrical stimulation, to create a system to restore gait. The hybrid system allows better control over the swing phase of gait and enables subjects with spinal cord injury to walk further before fatigue. (Completed)

Functional assessment using tele-rehabilitation technology

In this project, we are developing new tele-rehabilitation technology for doing assessment at a distance. Standard PT and OT assessment tools are implemented so that an assessment session can be conducted at a distance. Experiments are conducted to compare tele-assessment with traditional face-to-face assessment. This project is in collaboration with Sister Kenny Rehabilitation Services. (Pilot work ongoing, funding pending)

 PHS 398/2590 (Rev. 05/01)Page 1Continuation Format Page

Principal Investigator/Program Director (Last, first, middle): DURFEE, WILLIAM K.

BIOGRAPHICAL SKETCH
Provide the following information for the key personnel in the order listed for Form Page 2.
Follow the sample format for each person. DO NOT EXCEED FOUR PAGES.
NAME
CENTER, BRUCE A. / POSITION TITLE
ASSISTANT PROFESSOR
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / YEAR(s) / FIELD OF STUDY
University of Minnesota / Ph.D. / 1983 / Educational Psych.
University of Rochester / B.A. / 1970 / Psychology

A. Positions and Honors.

PROFESSIONAL EXPERIENCE

1998 to presentAssistant Professor and biostatistician, Department of Family Practice and Community Health, University of Minnesota.

1997 to 1998Instructor, graduate level , Statistics and statistical software, Division of Educational Psychology, University of Minnesota

1992 to 1997Instructor, graduate level Statistics, College of Business Administration, University of St. Thomas. Instructor, undergraduate level Statistics, Dept. of Quantitative Methods and Computer Science, University of St. Thomas.

1992 to 1997Independent Statistical Consultant: Advised faculty, researchers, and graduate students regarding experimental design, statistical analysis, and interpretation of results. Advised private industry on statistical software and install these as required.

1983 to 1992Supervising and Senior Analyst Programmer, Computer and Information Services, University of Minnesota: Supervised the Statistical Help Line for all University of Minnesota academic computing. Hired, trained, and evaluated personnel. Oversaw the conversion of SPSS to several Cray and the Convex supercomputers. Served as statistical consultant of last resort for computer system users. Taught classes in SAS and SPSS. Installed, tested, and maintained all statistical software on VAX VMS, Cyber NOS, and Encore Unix systems. Authorized payment for and ensured contract compliance with vendors of the University’s statistical packages.

1978 to 1980Cybernet division, Control Data Corporation: International statistical consultant of last resort for Cybernet users of SPSS and SIR. Evaluated statistical proposals for the Cybernet sales force and made presentations to customers.

B. Selected peer-reviewed publications (in chronological order).

PUBLICATIONS

Center, B. A., Skiba, R. J., & Casey, A. (1985-86). A methodology on the quantitative synthesis of intra-subject design research. Journal of Special Education, 19, 387-400.

Yeazel, M., & Center, B. A. (2001). A Demonstration of the Effectiveness and Acceptability of Self-Study Module Use in Residency Education. Academic Medicine, (submitted).

Smith, M. A., Brown, M. E., Borowsky, S. J., Davis, M. K., Center, B. A., & Lurie, N. (2001). Measuring the Physician Perspective on Quality of Care in Health Plans. Evaluation & the Health Professions, 24, (1) 18-35.

Strowig, A. B., Gaichas, A., Hill, A., Center, B. A. (2001). Risk Factors for RelapseAmong Men Treated For Alcohol Addiction: The Problem of Prediction. Journal of Alcohol Treatment (submitted).

Murphy, K. A., Yeazel, M., & Center, B. A. (2000). Validity of Residents’ Self-Reported Cardiovascular Disease Prevention Activities: The Preventive Medicine Attitudes and Activities Questionnaire. Preventive Medicine, 31, 241-248.

Hepburn, K. W., Tornatore, J., Center, B. A., & Ostwald, S. W. (2000). Dementia Family Caregiver Training: Affecting Outlook and Outcomes. Journal of the American Geriatrics Society.

Elbedour, S., Center, B. A., Maruyama, G. M., Assor, A. (1997). Physical and Psychological Maltreatment in Schools: The Abusive Behaviors of Teachers in Bedouin Schools in Israel. School Psychology International, 18, 201-215.

Elbedour, S., Bastien, D. T., & Center, B. A. (1997). Identity Formation in the Shadow of Conflict: Projective Drawings by Palestinian and Israeli Arab Children from the West Band and Gaza. Journal of Peace Research, 34, (2), 217-231.

RESEARCH PRESENTATIONS

Center, Bruce A. (2000, Dec.) Survey Development in a Less than Perfect World: Design and Validation of the PMAAQ. 15th Annual Primary Care Research Methods & Statistics Conference, San Antonio, Texas.

Center, Bruce A. (1991, June). The trailing edge of technology. Annual meeting of SPSS Academic Users Conference, Montreal, Canada.

Center, Bruce A. (1986, June). The piece-wise regression approach to meta-analysis for single-subject designs. Annual meeting of the Society of the Advancement of Behavior Analysis, Milwaukee, Wisconsin.

 PHS 398/2590 (Rev. 05/01)Page 1Continuation Format Page

Principal Investigator/Program Director (Last, first, middle):DURFEE, WILLIAM K.

BIOGRAPHICAL SKETCH
Provide the following information for the key personnel in the order listed for Form Page 2.
Follow the sample format for each person. DO NOT EXCEED FOUR PAGES.
NAME
HUIZENGA, NANCY RUTH / POSITION TITLE
DIRECTOR,
COMMUNITY BASED & VOCATIONAL SERVICES
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / YEAR(s) / FIELD OF STUDY
Ohio Wesleyan University / B.A. / 1977 / Sociology/Anthropology
University of Glasgow – Scotland / Credits earned towards B.A. / 1975-1976 / Medicine/Parasitology
University of Wisconsin – Madison / M.A. / 1979-1980 / Rehabilitation Counseling

Professional Experience:

January 1981 – November 1983Curative Rehabilitation Center, Green Bay, WI

Independent Living Skills Coordinator

One of three staff to initiate pilot program designed to enable individuals with severe physical disabilities to live independently; with primary responsibility for developing and implementing assessment process, training curriculums, case management system, and recreational programming. Provided personal adjustment counseling and other supportive services. Designed and coordinated attendant care program. Supervised student field placements.

December 1983 – April 1985Associated Rehabilitation Consultants, Inc. Minneapolis, MN

Rehabilitation Consultant

Determined medical and vocational status of injured workers. Developed and coordinated rehabilitation plans through consultation with employers, physicians, attorneys and other professionals. Provided medical management, job-seeking skills training and job placement services.

April 1985 – May 1990Courage Center Residence, Golden Valley, MN

Vocational Counselor

Provided vocational and educational counseling, career planning, assessment, selective training and job placement services to individuals with congenital disabilities or spinal cord injuries. Responsible for assisting residents in identifying their vocational potential and options, setting realistic vocational goals and plans to achieve their goals. Functioned as a member of and consultant to a transdisciplinary rehabilitation team. Coordinated service plans with community agencies. Supervised masters level student internships.

May 1990 – September 1995Courage Center Residential Services, Golden Valley, MN

Independent Living Skills Program Coordinator

Responsible for management and coordination of all components of the Independent Living Skills (ILS) Program and Argyle Residence: ensuring growth and development of the programs; management of programs’ budgets; hiring, orienting and supervising program staff; providing case supervision and management for clients in the ILS program; coordinating service plans with community agencies.