Candidate 2 (played by Chelsea), PhD
Somewhere in Waltham, MA 02452
Phone: xxx-xxx-xxxx; Email:
SUMMARY:
- Ph.D.-level molecular/cellular biologist with more than 10 years of experience in cancer research (leukemia/lymphoma, lung cancer, breast cancer)
- Excellent oral and written communication skills
- Team-oriented with strong leadership and interpersonal skills
EXPERIENCE:
Nationally Recognized Consortium 2012 - Present
Visiting Postdoctoral Scholar
Cancer Program–interdisciplinary research group focused on elucidating the molecular mechanisms underlying cancerusing large-scale genomic data
- Utilizedwhole-genome/whole-exome sequencing, RNA-Seq, gene expression profiling, and copy number data to identify genetic factors underlying inherited predisposition to chronic lymphocytic leukemia (CLL)
- Analyzed germline variants in 243 CLL patients and 9,773 normal controls
- Served as key liaison across a multifunctional team composed of cellular/molecular biologists, geneticists, computational biologists, biostatisticians, and clinicians
Nationally Recognized Cancer Institute 2011-Present
Postdoctoral Fellow
PI name Laboratory - translational and clinical research laboratory focused on identifying novel therapies against CLL
- Managed multiple projects involving the use of molecular and cellular tools to investigate the biological relevance and clinical utility of somatic mutations identified in 160 CLL patients
- Investigated theinteraction of small molecule inhibitors with patient mutational status
- Performed cell-based assays for mechanism of action identification and downstream pathway characterization
Contract Research Organization 2011
Intern
Cell Culture and Scale-Up Laboratory - protein expression facility that uses industry leading platforms to alleviate bottlenecks in industry pipelines
- Provided laboratory supportthrough maintenance of large-scale cultures, organization of inventory and records, aid in late night/weekend shifts, etc
- Assisted the Assay Services Laboratory in assay design
Well-ranked biomedical PhD program 2005-2011
Ph.D. Student
PI names Laboratories - basic research laboratories focused on understanding the role of nicotinic receptors in addiction, neuropsychiatric diseases, and cancer
- Initiated a new research niche in the laboratory through the investigation of the function of nicotinic acetylcholine receptor genes in lung cancer
- Comprehensively analyzed expression levels of all 11 human nicotinic receptor subunit genes across 26 different lung cell lines and 123 lung tissues
- Developed a high-throughput assay for automatedscreening of a 1,280-compound library against small cell lung carcinoma
UniversityAbroad 2003-2005
University Researcher
Biological Research and Services Laboratory – core facility that provides biological services, lab space, equipment, and training for research groups
- Supervised 4 laboratory personnel and trained18 high school students, 24 undergraduates, 4 interns, 7 medical students, and 13 graduate students
- Designed 4 hands-on workshops on molecular biology and genetics
- Wrote various types of documents (SOPs, training course modules, technical reports for clients, etc).
LABORATORY SKILLS:
Cell banking, DNA/RNA/protein isolation, molecular cloning, site-directed mutagenesis, standard PCR, real-time qRT-PCR, Western blotting, co-immunoprecipitation, chromatin immunoprecipitation (ChIP), mammalian cell culture, viability and proliferation assays (MTT, CellTiter-Glo, BrdU staining), apoptosis assays (TUNEL, Annexin V, Caspase-Glo), soft agar assay, luciferase reporter assay, immunohistochemistry, flow cytometry, transfection, electroporation, nucleofection, lentiviral transduction, RNA interference (siRNA,shRNA), fluorescence microscopy, in vivo xenograft mouse models, i.p./s.c. drug injections, non-invasive live animal imaging
EDUCATION:
Well-ranked biomedical program 2005-2011
Ph.D. in Biomedical Sciences
Dissertation: Expression and function of nicotinic acetylcholine receptors in lung cancer
University Abroad 1996-2000
B.S. Molecular Biology and Biotechnology
Thesis: Expression profiling of hormone receptors in breast carcinomas
SELECTED LEADERSHIP ROLES:
Postdoctoral and Graduate Student Association 2011-2014
- Co-Chair (date) – led the various initiatives of the organization
- Newsletter Writer/Editor (date) –wrote, edited, and designed page layout for the association’s newsletter, The Postdoc Times
- Retreat Committee Co-Chair (date) – organized the annual retreat for fellows and students
SELECTED HONORS AND AWARDS:
- Abstract Achievement Award, American Society of Hematology (date)
- Abstract Achievement Award, American Society of Hematology (date)
- Hot Topic, Society for Neuroscience 40th Annual Meeting (date)
- Outstanding Poster, Neuropsychiatry Day, School ofGraduate Program (date)
- Fellowship, Regional Training Course on Bioinformatics, World Health Organization (date)
PEER-REVIEWED PUBLICATIONS:
- First author,Hematology/Oncology Clinics of North America.
- First author, 2013. Frontiers in Physiology.
- First author, 2011. Biochemical Pharmacology.
- First author, 2011. PLoS ONE.
- Third author, 2011. Neuropsychopharmacology.
- First author, 2010. Oncogene.
- First author, 2010. Progress in Neurobiology.
- First author, 2010. Molecular Cancer Research.
SELECTED ORAL/POSTER PRESENTATIONS (8 out of 25):
- Poster at 56th American Society of Hematology Annual Meeting, San Francisco, CA (date).
- Oral presentation at 56th American Society of Hematology Annual Meeting, San Francisco, CA (date).
- Poster at 55th American Society of Hematology Annual Meeting, New Orleans, LA (date). *Received Abstract Achievement Award.
- Oral presentation at 55th American Society for Hematology Annual Meeting and Symposium, New Orleans, LA (date).
- Poster at 54th American Society of Hematology Annual Meeting, Atlanta, GA (date). *Received Abstract Achievement Award.
- Oral presentation at54th American Society of Hematology Annual Meeting and Symposium, Atlanta, GA (date).
- Poster/oral talk at Society for Neuroscience 40thAnnual Meeting, San Diego,CA (date). *Received 2010 Hot Topic Award.
- Poster at Meeting on Mechanisms & Models of Cancer, ColdSpring Harbor Laboratory, Cold Spring Harbor, NY (date).