Results

RESULTS

Table (1): Correlation between pathology and age of patient

Pathology / No. of cases / age / sex / Mean age

Benign lesions

Fibroadenoma
Fibrocystic disease
Ductectasia
Chronic abscess
Lipoma / 16
4
4
2
1 / 14-40
36-50
45-55
28-45
32 / 25.5
43.7
49
36.5
32
total / 27
Malignant lesions

Non-invasive carcinoma

Ductal
Lobular

Invasive carcinoma

Ductal
Lobular
Medullary
Colloid
Paget’s disease / 5
1
4
30
24
2
1
2
1 / 40-52
45-60
36-60
43-50
35-45
60-75
50 / 50.9
46
40.5
65
50
total / 35

Table (2): Clinical findings in benign breast lesions

Clinical examination

Pathology / No. of cases / Clinical findings / No. of cases
Fibroadenoma / 16 / Firm or rubbery freely mobile and delineated from surrounding tissue. No change in size during menstrual cycle. / 13
3

Fibrocystic disease

/ 4 / Mass with pain and nodularity.
Serosanguinos discharge. / 3
1
Ductectasia / 4 / Burning discomform in the breast.
Nipple discharge, greenish, serous or bloody. / 4

Lipoma

/ 1 / Soft pooly demarcated.
Can not separated from surrounding tissue mainly superfacial. / 1
Chronic abscess / 2 / Nipple discharge.
Retracted nipple.
Subareolar thickening. / 1
1
2

Table (3): Clinical findings in malignant breast lesions

Clinical examination

Pathology / No. of cases / Clinical findings / No. of cases
Non-invasive carcinoma / 5 / Induration
With discharge
Without discharge / 5
1
4

Invasive ductal carcinoma

Ductal / 30
24 / Firm nodular fixed mass
Hard mass
Retracted nipple
Firm mobile mass / 9
10
3
3
Lobular carcinoma
Medullary carcinoma
Colloid / 2
1
2 / Mass slightly fixed
Mass slightly mobile
Induration
Mass smooth palpation, not fixed / 2
1
1
2

Paget’s disease

/ 1 / Inflammatory eczematous condition of nipple. / 1
Total / 35

Table (8): Ultrasound findings in benign breast lesions

ultrasound findings

Histopathology /

No. of case

/ shape / No. of case / margin / No. of cases / echogenicity / No. of cases
Fibroadenoma / 16 / Well-defined mass / 16 / Smooth well-defined margin
-rounded
-oval
-lobulated / 4
9
3 / Homogeneous
-isoechoic
-hypoechoic / 2
14
Fibrocystic changes / 4 / Areas of fibrous stroma that appear brighter than the parenchyma
Small cysts scattered in the parenchyma
Large cysts more than 1 cm. / 3
1 / - / Variable echogenicity according to predominance of fibrous and cystic component / 4
Ductectasia / 4 / Subareolar variable sized dilated ducts regular or tortuous ducts / 4 / Well-defined / 4 / Variable echogenicity according to contents / 4

Table (9): Ultrasound findings in benign breast lesions

ultrasound findings

Histopathology /

No. of case

/ Shape / No. of case / Margin / No. of cases / Echogenicity / No. of cases
Lipoma / 1 / Rounded hypoechoic mass
Difficult to detect / 1
1 / -Smooth wall and regular margin.
-Not defined / 1
- / - Compressible
- low level echoes
- poorly defined through fatty breast / 1
Chronic abscess / 2 / Irregular shape / 2 / Ill-defined borders / 2 / - Posterior enhancement
- Hypoechoic or heterogeneous
Ill-defined irregular skin thickening / 1
1
Total / _

Table (10): Ultrasound findings in malignant breast lesions

Ultrasound findings

Histopathology /
No. of case
/
Shape
/ No. of case / Margin / No. of cases / Echogenicity / No. of cases
Non-invasive carcinoma
-Ductal
-Lobular / 1
4 / Small mass
with irregular shape
Size 0.5-1cm.
Not defined / 2
3 / irregular ill-defined margin
not defined / 2
3 / Non-homogeneous mass with posterior attenuation
Diffuse internal echogenicity / 1
4
Invasive carcinoma
a- ductal / 24 / Mass with irregular shape
Size 1-5 cm / 24 / Ill-defined borders / 24 / - Posterior enhancement
- Hypoechoic or heterogeneous
Ill-defined irregular skin thickening / 12
20
18
b- lobular / 2 / Irregular shape, parenchymal distortion
No detected mass / 2
1 / Irregular wall / Hypoechoic mass, irregular lateral and anterior walls
Echogenic with absent posterior wall attenuation.
Posterior shadowing with heterogeneous area. / 1
1

Table (11): Ultrasound findings in malignant breast lesions

ultrasound findings

Histopathology

/ No. of case / Shape / No. of case / Margin / No. of cases / Echogenicity / No. of cases
C- Medullary / 1 / Round
Oval.
Lobulated / 1
-
- / -Smooth but with non-uniformity.
-Well-defined margin / 1
- / - Non-homogeneous internal echoes.
- Posterior enhancement / 1
D- Colloid / 2 / Round
Oval / 1
1 / well-defined margin / 2 / -Circumscribed hhypoechoic mass with distal sound enhancement / 2
Paget’s disease / 1 / Irregular mass.
Distortion or parenchyma / 1 / Irregular ill-defined margin / 1 / Heterogeneous internal echoes.
Thick deformed skin. / 1
Total / 35

Table (12): Color Doppler flow in benign breast lesions

Doppler flow

pathology /

No. of cases

/ No. of cases with presence of flow / No. of cases with no flow / Cases with No. of vessels 1-3 / Cases with No. of vessels 4-5 / Cases with No. of vessels more than 5 / Site of flow
Peripheral / Central
Fibroadenoma / 16 / 10 / 6 / 2 / 5 / 3 / 9 / 1
Chronic abscess / 2 / 1 / 1 / 1 / 1
Lipoma / 1 / - / 1 / 1 / 1
Fibrocystic disease / 4 / 1 / 3
ductectasia / 4 / 1 / 3
Total / 27 / 13 (48%) / 14 (52%) / 4 (14.8%) / 5 (18.5%) / 3 (11.1%) / 10 (37%) / 2 (7.4%)

Table (13): Color Doppler flow in malignant breast lesions

Doppler flow

pathology /

No. of cases

/ No. of cases with presence of flow / No. of cases with no flow / Cases with No. of vessels 1-3 / Cases with No. of vessels 3-4 / Cases with No. of vessels more than 5 / Site of flow
Peripheral / Central
Non-invasive carcinoma / 5 / 2 / 3 / 3 / 1 / - / 4 / 4
Invasive carcinoma / 30
a- ductal / 24 / 20 / 4 / 16 / 4 / - / 20 / 20
b- Lobular / 2 / 1 / 1 / 1 / - / -
C- Medullary / 1 / 1 / - / 1 / -
d- Colloid / 2 / - / 2 / - / - / -
Paget’s disease / 1 / 1 / - / 1 / - / -
Total / 35 / 25 (71.4%) / 10 (28.5%) / 18 (51.4%) / 5 (14.2%) / 24 (68.5%) / 24 (68.5%)

Table (14): Correlation between mammography and pathology

Histopathology / No. of cases / No. of cases diagnosed / sensitivity
Benign lesions
Fibroadenoma / 16 / 9
Fibrocystic disease / 4 / 3
Ductectasia / 4 / 2
Chronic / 2 / 1
Lipoma / 1 / -
Total / 27 / 16 / 65%
Intermediate / 11 / 35%
Malignant lesions
Non-invasive carcinoma / 5 / 3
Invasive lesions / 30
-ductal / 24 / 22
-lobular
- / 2 / 1
Medullary / 1 / 1
Colloid / 2 / 1
Paget’s disease / 1 / 1
Total / 26 / 79%
Equivocal / 35 / 9 / 21%

Table (15): Correlation between ultrasound and pathology

Histopathology / No. of cases / No. of cases diagnosed / Sensitivity %
Benign lesions / 27
Fibroadenoma / 16 / 12
Fibrocystic disease / 4 / 4
Ductectasia / 4 / 4
Chronic abscess / 2 / 1
Lipoma / 1
Diagnosed cases / total / 21 / 81%
Equivocal / equivocal / 6 / 19%
Malignant lesions / 35
Non-invasive carcinoma / 5 / 1
Invasive lesions / 30
-Ductal / 24 / 22
-Lobular
- / 2 / 1
- Medullary / 1 / -
- Colloid / 2 / -
Paget’s disease / 1 / 1
Diagnosed cases / Total / 24 / 75%
Equivocal / 11 / 25%

Table (16): Sensitivity of clinical examination in diagnosis of breast lesions

Histopathology / No. of cases / Clinical examination / No. of cases / Sensitivity %
Benign / 27 / Benign / 17 / 63%
Malignant / 35 / Malignant
intermediate / 25
10 / 71%
32.25%
Total / 62 / Total diagnosed cases / 42 / 67.7%

Table (17): Sensitivity of mammography in diagnosis of breast lesions

Histopathology / No. of cases / Mammographic diagnosis / No. of cases / %

Benign lesions

/ 27 / Highly suspicious benign
Intermediate benign / 18
9 / 66.5%
33.5%
Malignant lesions / 35 / Highly suspicious malignant
Intermediate malignant / 29
6 / 83%
17%
Total / 62 / Total diagnosed cases / 47 / 75%

Table (18): Sensitivity of color Doppler in diagnosis of breast lesions

Histopathology / No. of cases / CDUS diagnosis / No. of cases / %
Benignlesions / 27 / Highly suspicious benign
Intermediate benign / 22
5 / 81%
19%
Malignant lesions / 35 / Highly suspicious malignant
Intermediate malignant / 27
8 / 76%
24%
Total / 62 / Total diagnosed cases / 42 / 79%

Table (19): Sensitivity of color Doppler flow in diagnosis of breast lesions

Histopathology / No. of cases / Color Doppler flow / No. of cases / sensitivity %

Benign lesions

Malignant lesions
Total / 27
35
62 /

Highly suggestive benign

Highly suggestive malignant

Total

Equivocal / 13
24
37
25 / 48%
68.5%
60%
40%

Table (20): Mean values of resistivty indices of benign and malignant lesions

Pathology / No. of cases with Doppler flow / Resistivity indices
(mean value)
Benign / 13 / 0.1-0.8
0.85
Malignant / 24 / 0.5-1
0.92

Total

/ 37

Table (21): Mean values of pulsatility indices of benign and malignant lesions

Pathology / No. of cases with Doppler flow / Pulsatility indices
(mean value)
Benign / 13 / 0.2-1.8
1.59
Malignant / 24 / 0.4-3
2.3
Total / 37

Table (22): Combined clinical examination and mammography diagnosis of breast masses

Pathology / No. of cases / Clinical examination and mammography no. of cases / Sensitivity %
Benign / 27 / 20 / 74%
Malignant / 35 / 30 / 85%
Total / 62 / 50 / 80%

Table (23): Combined mammography and ultrasound in diagnosis of breast masses

Pathology / No. of cases / Mammography and US diagnosis / No. of cases / Sensitivity %
Benign / 27 / High suggestive benign / 24 / 88%
Malignant / 35 / High suggestive malignant / 28 / 80%
Total / 62 / 52 / 84%

Table (24): Combined CDF and US in diagnosis of breast lesions

Pathology / No. of cases / CDF and US diagnosis cases / No. of cases / Sensitivity %
Benign / 27 / High suggestive benign / 23 / 85%
Malignant / 35 / High suggestive malignant / 30 / 85.7%
Total / 62 / Total sensitivity
Equivocal / 53
9 / 85.4%
14.5%

Table (25): Correlation between antero-posterior/transverse diameter in breast lesions

Pathology / No. of cases / No. of cases by US / AP/T ratio
AP/T more than 1 / % / AP/T less than 1 / %
Suspected benign / 27 / 22 / 3.5 / 15% / 18 / 85%
Suspected malignant / 35 / 27 / 24 / 90.5% / 3 / 11.3%

Table (26): Correlation between type of flow in vascular malignant and vascular benign lesions

Pathology / No. of cases / Type of flow
Turbulent flow / All types flow
Benign / 27 / 4 (26%) / 9 (76%)
Malignant / 35 / 23 (65.7%) / 11 (34.2%)
Total / 62 / 27 / 20

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