HLSC3410,Spring Semester,2017

PATHOPHYSIOLOGY

HLSC3410,Spring Semester,2017.

Pathophysiology, the altered physiology that results from deviations in health and wellness, explores the cellular alterations associated with changes in normal physiological function which result in pathologic processes. Etiology, pathogenesis, clinical manifestations and clinical course of the disease will be emphasized. Mechanisms of disease states will focus on alterations at the molecular level, how cell function changes affecttissue and organ system function(s), preventing or limitinghomeostatic adaptive responses, and the relationship to the disease processes of the body.

COURSE DIRECTOR: Dr. Barry Potter

Co-Director: Dr. Stefany Primeaux

The Course Director is directly responsible for the supervision and administration of HS3410, Pathophysiology. Any policy or schedule changes will be formally announced by Dr. Primeaux or Dr. Potterin class e-mails. Regular e-mails will also be sent, both individually & to the entire class. Please read these promptly as no other information will be given.

Members of the teaching staff include:

INSTRUCTOROFFICE TELEPHONEemail address

Barry J. Potter, Ph.D. (Course director) MEB7C10

Stefany D. Primeaux, Ph.D. (Co-Director)

Lauri Byerly, Ph.D.MEB

Anthony Duplanty, Ph.D.MEB

Scott Edwards, Ph.D.MEB

Tracey Knaus, Ph.D.MEB

Mr. Alan

Dr. Amanda

Xinping Yue, Ph.D.MEB

While telephone numbers have been provided, the most reliable way of contacting faculty or the course director is via e-mail. If you do so, please include HLSC 3410 TRAD in the subject heading or it will not be answered promptly (especially as most faculty members also teachon other courses).

Tutoring will be available on a limited basis by Mr. Jacques Mayeux, a graduate student in the Department of Physiology. Contact with Mr. Mayeux should be via e-mail at

Office hours for the Course Director Co-Director are normally by appointment - although appointments with Dr. Potter & other faculty may be requested for other times. Weekly changes due to other commitments) will be posted outside their offices. Office hours for other faculty will be posted on Moodle once the course has started and students can also request specific times & dates to meet with individual faculty.

LECTURES, ATTENDANCE, TEXTBOOK

Classes will be held in Lecture Room A on the second floor of the Nursing/Allied Health Building & exams in the NTSC facility on the 5th floor. Please note that there is absolutely no eating or drinking in these rooms.Use of computers is permitted during lectures for following class handouts & writing notes on the lectures. Any other use during class time is not permitted & may result in withdrawal of this privilege. NO RECORDING OF THE LECTURES OR PHOTOGRAPHY IS PERMITTED. Students may have access to recordings of earlier lectures at the instructor’s discretion.

Class begins at 8 AM!Class attendance is mandatory, and is checked at random. Lectureswill supplement extendthe textbook. The textbook will help you understand basic pathophysiologic concepts so you can apply them to nursing care. Achieve a working knowledge of the disturbances to normal physiology; don’t just memorize facts. Lecture material present in the handouts that is not in the textbook will, however, also be tested in the examinations. It is assumed that you have a comprehensive knowledge of normal physiology, as this will not be detailed during the lectures but may be tested in the sectional exams.Specific case studies will also be posted on Moodle. These are intended to translate the basic science into “real life”. The case studies will not be on the sectional exams per se but similar cases will form the basis for the comprehensive final examination.

Unavoidable absences require documentation for that absence – physician’s excuse, court documentation, death certificate, etc. You may lose 50 grade points from your total grade for each unexcused absence. After three unexcused absences, you will be administratively dropped from the course.

You are responsible for ALL the presented and assigned material. The textbook is required reading.The required booksare Essentials ofPathophysiology, 4e,by C.M. Porth (ISBN 978-1-4511-9080-9).It is also recommended that you purchase the accompanying study guide (Study guide for Porth’s essentials of pathophysiology, 4th edition – ISBN: 978-1-4511-9293-3) which will help you study & prepare for exams.The Essentials of Pathophysiology text is well written with numerous diagrams and illustrations. We do not intend that you master the details of all the information in the book. We ask that you know where to find an answer to your questions. We may approach the topic and explain it differently from that found in the course textbook, but the lectures supplement & extend the textbook readings. You will be responsible for all of the material presented in class & on Moodle.

The handouts for the classes will be distributed weekly via Moodle. For the Spring term, students may also be able to access similar lectures via the archives (the dates of the appropriate lectures will be posted on Moodle) until the next sectional exam relating to those recordings. While these will cover the same material, they will not be identical to the live presentations & handouts will not be provided for these. Students wishing to use this resource must ensure that they are able to access these via the LSUHSC School of Nursing website by the second week of class. All enquiries, problems, etc, relating to access to Moodle, & the archives should be via e-mail to Mr. Marco Sosa, or other IT personnel at the School of Nursing. IT IS THE STUDENTS RESPONSIBILITY TO ENSURE THEIR ACCESS TO ALL OF THESE PROGRAMS! While students may access the archives & use laptops for note-taking during lectures, it is LSUHSC-SON policy that live lectures are not to be recorded. Any infringement of this policy will result in a failing grade & disciplinary action by the school.

ACADEMIC HONESTY:

You may be asked to sign and comply with an honor code for each exam. The Health Sciences Center policy on cheating and plagiarism, as stated in the catalogue, will be strictly enforced..Students found cheating in any form, will receive an automatic failing grade for the course and their names will be sent to the Dean of the Nursing school for further disciplinary action.

STUDENTS WITH DISABILITIES: Students with disabilities must inform the Nursing School Administrative Assistant Dean of their authenticated disability. They will inform the course director that the student will require additional time or accommodations and remind him at least 48 hours before each exam. It is the student’s responsibility to contact the course director no later than 24 hours prior to each examination to receive details of the arrangements.

EXAMINATIONS (700 Points):

Five sectionexaminations (100 point each) and one comprehensive final, multiple-choice in nature (200 points), are scheduled, as may be seen below. You may be asked to sign and returnan honor code, and comply with it. In accordance with The School of Nursing Compliance Regulations, you can be requested to take a new examination if discrepancies are noted in your work.

You may carry a pencil and pieces of scrap paper with you into the exam. The scrap paper must be left behind when you leave. Nothing else is permitted. LEAVE CELL PHONES in your book bag! If you expect an emergency call during the exam, silence your cell phoneleave it with the proctors so we can notify you should you receive a call. Caps and other headgear MAY NOT be worn during the exam, apart from those related to religious doctrines. All books, backpacks, purses, cell phones, iPods, computers, book bags and other material MUST be stored in designated areas, off the floor, out of the way!

On examination day do not enter the room until instructed by the proctor. Exam instruction will start at 7.55 am. Get seated rapidly! Sectional exams are limited to exactly 1 hour, and will start AFTER instructions are given. Should you arrive late for the exam, your exam will end at the same time as the other students. Should you arrive twenty minutes after the exam starts, you will have missed the exam, and will have to make arrangements to take a make-up exam.

Questions (multiple choice) will be from both lecture and textbook material; some will be based on current as well as previously covered principles. Questions will ask you to apply principles learned in the lectures and reading to a clinical situation. If you understand the concepts, if you have learned essential details, then you should do well. NCLEX-type questions may also be included in the exams.

Section exams may be comprehensive such that the nature of the material presented each unit is built on earlier concepts; this includes the normal physiology. Each exam may cover material from the previous section.

Missing an Exam:

Students must have a legitimate excuse for missing an examination. Please inform the course director BEFORE the exam, if possible. If a student misses an examination, has a written legitimate medical excuse, and informs the coordinator no later than 24 hours after the exam has been given, then the student will be offered a make-up exam. You must inform the course director no later than 24 hours after the exam is given why you were unable to take the exam.

Students with a valid excuse must take a “make-up” exam (usually an oral or essay exam) within one week of returning to school. It is the student’s responsibility to schedule this make-up exam! Failure to do so will result in a grade of “0” for any examination missed. Excused absences will include but not be limited to death of a family member or significant other, illness of student or dependent, accidents, authorized attendance at university activities.

STUDENT EVALUATION:

Evaluation is based on 5 unit exams (500 points),a comprehensive final exam (200 points), for a total of 700 points.Exams are evaluative, not instructional. We will NOT review exams or individual exam questions. Exam results will not be “curved”.

Final grades are determined from the total number of points from the exams, attendance, assignments, and the term paper. Grades will NOT be rounded up; you will have to score the absolute minimum points given below to earn your letter grade for the course.

Final Grades: Grades are based on 90% (A), 80% (B), 70% (C), 60% (D), and <60% (F):

A (90%)630-700 points

B (80%)560-629 points

C (70%)490-559 points

D (60%)420-489 points

F (<60%)000 - 419points

GRADES WILL NOT BE ROUNDED UP!

GRADES ARE CONSIDERED FINAL ONCE SUBMITTED TO THE REGISTRAR!

HLSC3410: PATHOPHYSIOLOGY Spring 2016

LECTURE SCHEDULE

DATE
[Suggested reading] / 8.00 am – 9.00 am / 9.00 am – 10.00 am / 10.00 am -11.00 am
01/23/2017**
[ Ch’s 1,2 & 4-6] / 1. Introduction to Course: Normal Cell Structure & function
[Potter] / 2. Cells, Disease & Cell Biology
[Potter] / 3. Genetic Disorders[Potter]
01/30/2017
[Ch’s 3, 14-16 ] / 4. The Molecular Biology of Cancer
[Potter] / 5. Infection & Inflammation
[Yue] / 6. Immune System-Related diseases
[Yue]
02/06/2017
[Ch’s 11-13] / SECTION EXAM #1
(Lectures 1-6) / 7. Hematologic Disorders: I – Erythrocytes
[Potter] / 8. Hematologic Disorders: II - WBCs & Plasma Factors
[Potter]
02/13/2017
[Ch’s 18-20] / 9. Atherosclerosis & other Vascular Disorders[Yue] / 10.Disorders of Cardiovascular Function [Primeaux] / 11. CAD & Cardiac Failure [Primeaux]
02/20/2017
[Ch’s 18-20] / SECTION EXAM #2
(Lectures 7- 11) / 12. Shock![Yue] / 13. Arrhythmias/ECG interpretation[Potter]
02/27/2017
[ Ch’s 8, 21-23] / 14. Disorders of the Respiratory System [Yue] / 15. Asthma, COPD & Emphysema [Yue] / 16. Blood Gases
[Potter]
03/06/2017
[Ch’s 8, 24-27] / SECTION EXAM #3
(Lectures 12-16) / 17. Fluid & Electrolyte Balance [Primeaux] / 18. Disorders of Renal Function [Potter]
03/13/2017
[Ch’s 28-30] / 19. Upper & Lower GI Disorders [Potter] / 20. Upper & Lower GI disorders ctd [Potter] / 21. Pancreatic & Liver Disorders [Potter]
03/20/2017
[Ch’s 10 & 33] / 22. Gut Microbiome & Disease [Potter] / 23. Nutritional Disorders [Byerly] / 24. Diabetes & Metabolic Syndrome
[Primeaux]
03/27/2017
[Ch’s 32, 39-40] / SECTION EXAM #4
(Lectures 17-23) / 25. Endocrine Disorders
[Primeaux] / 26. Reproductive Disorders [Primeaux]
04/03/2017
[Chs 42, 44 pp 860-868] / 27. Disorders of the Skeletal System [Duplanty] / 28. Metabolic & Rheumatic Disorders [Duplanty] / 29. Pain [Edwards]
04/10/2017
[Ch’s 9, 36-37] / 30. Disorders of Neuromuscular Function[Knaus]
[Knaus] / 31. Alterations in Brain Function
[Knaus] / 32. STRESS! [Mouton]
04/17/2016 / SPRING / BREAK/ / EASTER
04/24/2017 / SECTION EXAM #5
(Lectures 24-32) / 33. Addiction
[Pahng] / 34.Integrated Pathophysiology [Potter]
05/01/2017
05/08/2017 / COMPRE-HENSIVE
(12.00 -3.00) / FINAL
[Based on Case Studies] / EXAM

** Readings are from Essentials of Pathophysiology, 4e, by C.M. Porth.