Supplemental Alignment 1. Full length ClustalW multiple alignment
CLUSTAL W (1.83) multiple sequence alignment
CC50A_HUMAN ------
CC50B_HUMAN ------
Q8STD2_DROME ------
CC50C_HUMAN ------
Q19635_CAEEL ------
Q21844_CAEEL ------
CDC50_YEAST ------
YN8S_YEAST ------
LEM3_YEAST ------
Q655Y4_ORYSA ------
Q6H511_ORYSA ------
Q9LTW0_ARATH ------
Q9SLK2_ARATH ------
Q9SA35_ARATH ------
Q9SAK3_ARATH ------
Q653D8_ORYSA ------
Q0DGI4_ORYSA ------
Q10SJ9_ORYSA ------
Q1SP74_MEDTR ------
Q1T0V9_MEDTR ------
Q67YS6_ARATH ------
Q10CF0_ORYSA ------
Q4Q5N2_LEIMA ------
Q0P0L8_LEIDO ------
Q4QHS2_LEIMA MSMLPRSNSATVAPQPASGGGAPAFSVSMSSSRWPQRGASPPLTTSSQVPPSAESSSANS 60
Q4FWD0_LEIMA ------
CC50A_HUMAN ------MAMNYNAKDEVDGGPPCAPGG------21
CC50B_HUMAN ------MTWSAT------ARG------9
Q8STD2_DROME ------MSTQQAEN------EESA------12
CC50C_HUMAN ------MEERAQHC------8
Q19635_CAEEL ------MP--DDIPKLPRHRGK------14
Q21844_CAEEL ------MPPRDAVPTSTQVSGIGADGVQTE------24
CDC50_YEAST ------MVSLFKRGKAPPLTKEGP------18
YN8S_YEAST ------MGLILRWKEKKQLSSKQNAQ------20
LEM3_YEAST ------MVNFDLGQVGEVFRRKDKGAIVSGDNPEEEEDVDAS 36
Q655Y4_ORYSA ------MNNHAAGGSTSNGGSGVDGD------20
Q6H511_ORYSA ------MSSGQEAGSSS-GGS------14
Q9LTW0_ARATH ------MSSSNTPSSSAAAAGSID------18
Q9SLK2_ARATH ------MSSNTASSSAGAAGSGD------17
Q9SA35_ARATH ------MSTKKHNLLANFASSD------16
Q9SAK3_ARATH ------
Q653D8_ORYSA ------MPPVNSDGAGPSSGEDG------17
Q0DGI4_ORYSA ------
Q10SJ9_ORYSA ------MDPLESEGG------9
Q1SP74_MEDTR ------MMDMTSSKDGQSP------13
Q1T0V9_MEDTR ------MVDSR------5
Q67YS6_ARATH ------MMEVEGSMN------RAPDQ------14
Q10CF0_ORYSA ------MMEEASTSASGGGGAAANGG------20
Q4Q5N2_LEIMA ------MAPLPPKPHSK------11
Q0P0L8_LEIDO ------MAPLPPKPHSK------11
Q4QHS2_LEIMA SSSRTSSSYADSDDERCRVQGSGGGVRGAGNAAAVSAEAPKSRSTRAKLWLQKK------114
Q4FWD0_LEIMA ------MPVAPAAVVQRPS------13
CC50A_HUMAN ------TAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVT 71
CC50B_HUMAN ------AHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYS 56
Q8STD2_DROME ------AAKSKRPSDSAFKQQRLPAWQPVLTARTVLPTFFVIGVLFIPIGVVLLHL 62
CC50C_HUMAN ------LSRLLDNSALKQQELPIHRLYFTARRVLFVFFATGIFCLCMGIILILS 56
Q19635_CAEEL ------KNQPKDTPWKQQKLPALRPHYNITSAIPVTLITGVATLAMGIALYFG 61
Q21844_CAEEL ------KVLKNRPKASALRQQKLPAWQPILTATTVIPTVFVIGAIFLPIGVFLFIA 74
CDC50_YEAST ------TSKKPPNTAFRQQRLKAWQPILSPQSVLPLLIFVACIFTPIGIGLIVS 66
YN8S_YEAST ------KSRKPANTSFRQQRLKAWQPILSPQSVLPLLILMACVFAPIGIGLVVS 68
LEM3_YEAST EFEEDEVKPVRTKNRRPKEDAFTQQRLAAINPVLTPRTVLPLYLLIAVVFVIVGGCILAQ 96
Q655Y4_ORYSA --GGGGGGAARRNTKMPKYSKFTQQELPACKPILTPKWVVSVFFLVGVIFVPVGVVSLLA 78
Q6H511_ORYSA --GDGGAAAPRRNTRKPKYSKFTQQELPACKPILTPKWVISVFVLVGVIFVPIGLVSLKA 72
Q9LTW0_ARATH ------SSAARRNSKRPKYSKFTQQELPACKPILTPGWVISTFLIISVIFIPLGVISLFA 72
Q9SLK2_ARATH ------SSAARKNSKRPKYSKFTQQELPACKPILTPGWVISTFLIVSVIFIPLGVISLFA 71
Q9SA35_ARATH ------SRFTQQELPACKPILTPKWVILTFLVSGVVFIPLGVICLFA 57
Q9SAK3_ARATH ------MFTQQELPACKPILTPRWVILTFLVAGVVFIPLGVICLFA 40
Q653D8_ORYSA ------SAAAVKKRNRPKYHRFTQQELQACKPILIPQTVILVLVFVGLIFIPIGLACIAA 71
Q0DGI4_ORYSA ------MKPKYSKFTQQELPAWKPLYTPGIVIGAFSLIGIIFIPIGLVSIAA 46
Q10SJ9_ORYSA ------SQKSNNKPKYSKFTQQELPACKPLLTPGIVVATFLLIGIIFVPIGLASLSA 60
Q1SP74_MEDTR ------PNSKKTSKKPKYSKFSQQELPAWKPILTPGWVIATFTAIGIIFIPIGLASLFS 66
Q1T0V9_MEDTR ------FSQQELHAWQPILTPGWVIAIFTFIGLVFIPIGVASLFA 44
Q67YS6_ARATH ------SSFLRSRRSKALYQFKQQKLPACKPVLTPISVITVFMLMGFVFIPIGLITLRA 67
Q10CF0_ORYSA ------QRGFPPARSGVFYRFTQQNLPAWKPAMTPGCVITIFLMIGVTFVPVGLVCLHA 73
Q4Q5N2_LEIMA ------NRLEQQQLPHIYARYSPLSVSAVFFVLAVAAIPIGVVVIVS 52
Q0P0L8_LEIDO ------NRIEQQQLPHIYARHSPLSVSVVFFILAVAAIPIGVLVIVS 52
Q4QHS2_LEIMA ---LVPDFVHEYGRTVYGGNPLSQQTLPGVFNYPPPFILVPIFYVLMVPFLILGTLVLVK 171
Q4FWD0_LEIMA ------IWALFKQQRLPAWQPILTPQHSALCLIAVAVVCLPLSLSLFRA 56
** * :.
CC50A_HUMAN SNN------IREIEIDYTGTEPSSPCNKCLSPD------98
CC50B_HUMAN SNG------IKELEYDYTGDPGTGNCSVCAAAGQGRA------87
Q8STD2_DROME SNT------ANELIIDYTKCRRSGGNTTCAEYLEAN------92
CC50C_HUMAN ARS------TQEIEINYTR--ICANCAKLRENASN------83
Q19635_CAEEL HNG------SLEQEIVYTDCALSNGTQASRIMRTEM------91
Q21844_CAEEL SDA------VSEFTVEYTNCLSP------91
CDC50_YEAST ATK------VQDLTIDYSHCDTKASTTAFEDIPKKYIKYHFKSKVEN-- 107
YN8S_YEAST TIS------VQRLVVNYTECDALAPAKHFETIPSEYVDYHFSKKVAV-- 109
LEM3_YEAST NSK------VDEVTIYYQDCMTNATS-SWSDIPSEHWQFVFHKYKTYNT 138
Q655Y4_ORYSA AQN------VVEIVDRYDDACVPANMTDNKLAYIQNP------109
Q6H511_ORYSA SRK------VVEIVDRYDDACVPANTTD-KLAYIQNP------102
Q9LTW0_ARATH SQD------VVEIVDRYDSACIPLSDRANKVAYIQG------102
Q9SLK2_ARATH SQD------VVEIVDRYDTECIPAPARTNKVAYIQG------101
Q9SA35_ARATH SQGVCFKSFLTFLSYNYIYFVIEIVDRYDTDCIPLSSRDNKVRYIQG------104
Q9SAK3_ARATH SQGLRFCGFIEDMFHSYLK-VVEIVDRYDTDCIPTSSRNNMVAYIQG------86
Q653D8_ORYSA SNK------VVELVDRYDTKCVPRNMLRNKVAFIQNS------102
Q0DGI4_ORYSA SQE------VVELVDKYDGECVT---ANDKVGFIQDT------74
Q10SJ9_ORYSA SQE------IVELVDRYDTNCVS---TLDKVGFIQNT------88
Q1SP74_MEDTR SGK------VVEAEFRYDETCLSPDVAKDAVAYIKSD------97
Q1T0V9_MEDTR SEQ------VVEVPLRYDDQCLPSLYKDDAMTYIKGN------75
Q67YS6_ARATH SRD------AIEIIDRYDVECIPEEYRTNKLLYITDS------98
Q10CF0_ORYSA SNH------VAEIAHRYDIDCVPNAYKRNRQAYIKDS------104
Q4Q5N2_LEIMA GDL------TTRLDFRYDHINSYKFVMG----AADEYAVNFPFN----- 86
Q0P0L8_LEIDO GDL------TTRLDFRYDHINSYKFAMG----AAGEFAVNFPFN----- 86
Q4QHS2_LEIMA GRE------YHIVEQEYSHIHQYQYVPSNSSVNINHRILQFTAD----- 209
Q4FWD0_LEIMA NAS------AVDITVRYDHQQQCSFGYN------NTGAFRYEASP---- 89
*
CC50A_HUMAN ------VTPCFCTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQL 143
CC50B_HUMAN ------LPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDAQL 133
Q8STD2_DROME ------PGVTCPCEVPFVLPSDFNGVVYMYYGLTNYYQNHRRYVKSRDDEQL 138
CC50C_HUMAN ------FDKECTCSIPFYLSGKMMGNVYMYYKLYGFYQNLYLYIRSRSNRQL 129
Q19635_CAEEL ------GNQTFKCAYTITLNDDYTGEVKFYYGLSKFYQNNRLYFNSRNDQQL 137
Q21844_CAEEL ------CQLQINLPNAFDGDVFLYYNLENYYQNHRRYVKSRNDQQY 131
CDC50_YEAST KPQWR-LTENE----NGEQSCELQFEIPNDIKKSIFIYYKITNFYQNHRRYVQSFDTKQI 162
YN8S_YEAST QPQWMVLTDPE----LGNQTCRIQFEVPNHIKKSTYVYYRLTNFNQNYREYVQSLDLDQL 165
LEM3_YEAST APQWRFVDDESDDFTKQRGTCQIRFTTPSDMKNNVYLNYVLEKFAANHRRYVLSFSEDQI 198
Q655Y4_ORYSA ------NISKECTRTLTITEDMNQPIFVYYQLDNFYQNHRRYVKSRNDGQL 154
Q6H511_ORYSA ------TISKNCRRTLKVPKDMDAPIFVYYQLDNFYQNHRRYVKSRSDAQL 147
Q9LTW0_ARATH ------TGNKSCTRTLIVPKRMKQPIYVYYQLENFYQNHRRYVKSRSDSQL 147
Q9SLK2_ARATH ------DGDKVCNRDLKVTKRMKQPIYVYYQLENFYQNHRRYVKSRSDSQL 146
Q9SA35_ARATH ------LEDKRCNRTITVTKTMKNPVYVYYQLENYYQNHRRYVKSRQDGQL 149
Q9SAK3_ARATH ------EGDKICKRTITVTKAMKHPVYVYYQLENFYQNHRRYVKSRNDAQL 131
Q653D8_ORYSA ------SIDKTCTRVFKVPKDMKKPIYIYYQLDKFYQNHRRYVKSLNDMQL 147
Q0DGI4_ORYSA ------KTDKACTRTITVPKPMKGPIQVYYQLENFYQNHRRYVKSRSDKQL 119
Q10SJ9_ORYSA ------DTDKTCTRTLTVPKHMKSPIQIYYQIGDFYQNHRRYVKSRSDKQL 133
Q1SP74_MEDTR ------TTNKTCTHKWIVEQKMQAPVFIYYQLENYYQNHRRYVKSRNDKQL 142
Q1T0V9_MEDTR ------RISKTCTKKLTVKSKMKAPIYVYYQLSNFYQNHRHYVKSRDHKQL 120
Q67YS6_ARATH ------SIPKNCTRYLKVQKYMKAPIFIYYQLDNYYQNHRRYVKSRSDQQL 143
Q10CF0_ORYSA ------SISKNCTQEVKVKYLMRAPIYVYYELDNFYQNHRRYVKSRSDKQL 149
Q4Q5N2_LEIMA ------GTTYSSGVKTRLMFSLSQSLTAPVYMQYRLTPFFQNYRYFTASVDYVQL 135
Q0P0L8_LEIDO ------GTMYSSGVKTRLMFSLHQSLTAPVYMQYRLSPFFQNYRYFTASVDYSQL 135
Q4QHS2_LEIMA ------GVTHAQGTRTWLEINISHHMKAPVYMYYKIANMHQNHRDFHNGRSNSQL 258
Q4FWD0_LEIMA ------GDVWQTGCVTDVPFRVDKHLKAPVYVYYGLENFYQNHRRFSNSKSDAQL 138
. * : * : . . *
CC50A_HUMAN NGDSSA----LLNPSKECEPYR------RNED--KPIAPCGAIA 175
CC50B_HUMAN SGLPSA----LRHPVNECAPYQ------RSAAG-LPIAPCGAIA 166
Q8STD2_DROME LGHLS------QTPSTDCAPFA------YDPDTGKPIAPCGAIA 170
CC50C_HUMAN VGKDV------KAVEDCAPFK------MSDNK-TPIVPCGAIA 159
Q19635_CAEEL RGKVT------ETDGCDPLEY------VDVNGTKVPIAPCGKVA 169
Q21844_CAEEL LGDLT------NVKDCAPFD------IDP-ATKKPIAPCGAIA 161
CDC50_YEAST LGE----PIKKDDLDTSCSPIR------SRED-KIIYPCGLIA 194
YN8S_YEAST KGK----ALIGNDLDPNCDPLR------TVEN-KTIFPCGLIA 197
LEM3_YEAST RGEDASYETVHDATGINCKPLS------KNADGKIYYPCGLIA 235
Q655Y4_ORYSA RDAAKA------NQTSACEPE------KTTADGKPIVPCGLIA 185
Q6H511_ORYSA RDPKKA------NDTSTCDPE------GTANGMAIVPCGLIA 177
Q9LTW0_ARATH RSVKDE------NQIDACKPE------DDFGGQPIVPCGLIA 177
Q9SLK2_ARATH RSTKYE------NQISACKPE------DDVGGQPIVPCGLIA 176
Q9SA35_ARATH RSPKDE------HETKSCAPE------DTLGGQPIVPCGLVA 179
Q9SAK3_ARATH RSPKEE------HDVKTCAPE------DNVGGEPIVPCGLVA 161
Q653D8_ORYSA RNPKKV------ADTQYCSPE------ATANGRPIVPCGLIA 177
Q0DGI4_ORYSA RSKEFS------SVIKTCDPEA------I-SE-GGAPIVPCGLIA 150
Q10SJ9_ORYSA RYKNAV------HLTKDCDPEG------N-TV-DGAPIIPCGLIA 164
Q1SP74_MEDTR WRKSAE------LQTDHCDPVD------K-TE-GKEPIVPCGLIA 173
Q1T0V9_MEDTR RSKADE------NDVGKCFPED------Y-TANGYLPVVPCGLAA 152
Q67YS6_ARATH LHGLEY------SHTSSCEPE------ESSNGLPIVPCGLIA 173
Q10CF0_ORYSA RYGQKY------THSS-CDPI------ERNDGLPIVPCGLIA 178
Q4Q5N2_LEIMA SGR--GSAGS-TLCAPFRFPG------EATGDQVSG------YYNPCGAYP 171
Q0P0L8_LEIDO SGR--ASAIS-KLCAPFRFPG------EATGDSVSG------YYNPCGAYP 171
Q4QHS2_LEIMA RGK--STIKKPYLCQPYTYPGFRSDEGDTPITITDATGAQVTRPASYF---TYNPCGIAP 313
Q4FWD0_LEIMA AGQRVSAAAIASATSPLTYPG------ELRHTADQGINLLGTFLHYSDFVYVPAGLIP 190
* *.* .
CC50A_HUMAN NSMFNDTLELFLIGNDSY------P 194
CC50B_HUMAN NSLFNDSFSLWHQRQPGG------P 185
Q8STD2_DROME NSLFNDTLTLLQGGS------185
CC50C_HUMAN NSMFNDTIILSHNINSSV------Q 178
Q19635_CAEEL DSMFNDTFELFYINDKASN------A 189
Q21844_CAEEL NSIFNDTFTLAHRADTG------I 179
CDC50_YEAST NSMFNDTFSQVLSGIDDTE------D 214
YN8S_YEAST NSMFNDTFGTTLTGVNDTA------D 217
LEM3_YEAST NSMFNDTFPLQLTNVGDTS------N 255
Q655Y4_ORYSA WSLFNDTYSFTR--GNEN------201
Q6H511_ORYSA WSIFNDTYGFVR--NSKN------193
Q9LTW0_ARATH WSLFNDTYVLSR--NNQG------193
Q9SLK2_ARATH WSLFNDTYALSR--NNVS------192
Q9SA35_ARATH WSLFNDTYDFTR--NNQK------195
Q9SAK3_ARATH WSLFNDTYSFSR--NSQQ------177
Q653D8_ORYSA WSLFNDTYSFTRGHGNET------195
Q0DGI4_ORYSA WSLFNDTFTFSV--NKKT------166
Q10SJ9_ORYSA WSLFNDTYTISV--NKKA------180
Q1SP74_MEDTR WSMFNDTYKFSI--DNKD------189
Q1T0V9_MEDTR WSLFNDTYRFSN--NNKD------168
Q67YS6_ARATH WSMFNDTFTFSR--ERTK------189
Q10CF0_ORYSA WSLFNDTYGFTC--GSTE------194
Q4Q5N2_LEIMA WAIFNDSISLYRIDG------TLICDGSAFT-ANGTSLAP- 204
Q0P0L8_LEIDO WAMFNDSISLYRTDG------TLICDGSAFT-ANGTSLAA- 204
Q4QHS2_LEIMA WSKFNDTFILYRKLTPAEVLQANTSGIPVLHGGVDSTTPMTLICNGTDFG-LRGEPLHGS 372
Q4FWD0_LEIMA WSMFNDTFTLYRITHHEAAAVTAPS------LRLICNGSAFSRFTNEPLDG- 235
: ***:
CC50A_HUMAN -IPIALKKKGIAWWTDKN----VKFRNPP-GGD-NLEERFKG------TTK 232
CC50B_HUMAN YVEVPLDRSGIAWWTDYH----VKFRNPP-LVNGSLALAFQG------TAP 225
Q8STD2_DROME --EIKLLKTGIAWPSDKR----VKFRNP----EGNLNVSLEG------FSK 220
CC50C_HUMAN -IKVPMLKSRLTWWTDKY----VKFQNLS---FKNLADEFRGKIHTVAQYT------TTK 224
Q19635_CAEEL VTRVPWTTRGVLGATEMK----RKFRNPIRAENQTLCDVFAG------TMP 230
Q21844_CAEEL VTMVPVTTQGVIWNVDKD----RKFKNPP-LNDGNLCDAFNN------TTK 219
CDC50_YEAST ---YNLTNKHISWSIDRHRFKTTKYNASD------IVP 243
YN8S_YEAST ---YLLTTKGIAWDTDSHRYGKTEYNASD------IVP 246
LEM3_YEAST N--YSLTNKGINWESDKKRYKKTKYNYTQ------IAP 285
Q655Y4_ORYSA ---LTVDKKDISWKSDRE----HKFGKNV------Y 224
Q6H511_ORYSA ---LPVDKKNISWKSDRE----HKFGRDV------F 216
Q9LTW0_ARATH ---LTVNKKGIAWKSDKE----HKFGKNV------F 216
Q9SLK2_ARATH ---LAVNKKGIAWKSDKE----HKFGNKV------F 215
Q9SA35_ARATH ---LPVNKKDISWKSDRE----SKFGKNV------F 218
Q9SAK3_ARATH ---LLVNKKGISWKSDRE----NKFGKNV------F 200
Q653D8_ORYSA ---LRVNKDGISWKSERN----RRFGKNV------Y 218
Q0DGI4_ORYSA ---VQVNKKNIAWSSDRT----IKFGSDV------F 189
Q10SJ9_ORYSA ---IEVNKKDIAWKSDKT----DKFGSDI------Y 203
Q1SP74_MEDTR ---LTINKKNIAWGSDKN----SKFGHEV------Y 212
Q1T0V9_MEDTR ---LVINKKNIAWKSDQK----AKFGSDV------Y 191
Q67YS6_ARATH ---LNVSRNNIAWKSDRE----HKFGKNV------Y 212
Q10CF0_ORYSA ---IKVNRKNISWKSDRE----HKFGKDV------Y 217
Q4Q5N2_LEIMA --NNKCVKSGIARPSDVK----ARYRPPSEIPGNGP--MWSAG------G 240
Q0P0L8_LEIDO --NNKCVKSGIARPSDVK----ERYNPPREIPGNGP--MWSAG------G 240
Q4QHS2_LEIMA VTKNHCSKMGITWKADRE----VRFHN---ITLRED--WWSLY------Y 407
Q4FWD0_LEIMA --AGRCHKKGIAWTSDVE----FKYKKPHFPPPSSPRPVWSAPKWAYEAADGDVNPNPPS 289
: : .:
CC50A_HUMAN PVNWLKPVYMLDSD-----PDNNGFINEDFIVWMRTAALPTFRKLYRLIE-RKSD--LHP 284
CC50B_HUMAN PPNWRRPVYELSPD-----PNNTGFINQDFVVWMRTAALPTFRKLYARI--RQGN--YSA 276
Q8STD2_DROME PIFWQKGLADLDPEN----PDNNGFQNEDLIVWMRTAALPSFRKLYRRLNQTNTN--YAN 274
CC50C_HUMAN PPNWPKPIYDLDKKD----PRNNGFLNDDFIVWMRAAAFPTFKKLYGRLS-RTHH--FIE 277
Q19635_CAEEL PPSWRYPICQLGLNSIDP-DVGIGFENIDFMVWMKVAALPKFRKLYRILN-RQVD-MFSN 287
Q21844_CAEEL PPNWSKNPCEVG------GFENVDFIVWMRTAALPYFKKLWRIVD-RTTNPLFSN 267
CDC50_YEAST PPNWMKKYPDGYTDEN----LPDIHTWEEFQVWMRTAAFPKFYKLTLKNE------SA 291
YN8S_YEAST PPNWAKLFPNGYTDDN----IPDLQNWEQFKIWMRTAALPNFYKLAMKNE------TN 294
LEM3_YEAST PPYWEKMYPDGYNETN----IPDIQDWEEFQNWMRPGAFDKITKLIRINK------ND 333
Q655Y4_ORYSA PSNFQNGLLKGGGTLD---PAIPLSEQEDLIVWMRTAALPTFRKLYGRIY------VD 273
Q6H511_ORYSA PKNFQNGSLIGGKTLD---PNKSLSKQEDLIVWMRTAALPTFRKLYGRIH------TD 265
Q9LTW0_ARATH PKNFQKGNLTGGASLD---PNKPLSDQEDLIVWMRTAALPTFRKLYGKIE------SD 265
Q9SLK2_ARATH PKNFQKGNITGGATLD---PRIPLSEQEDLIVWMRTAALPTFRKLYGKIE------SD 264
Q9SA35_ARATH PKNFQKGSLIGGKSLD---QDIPLSEQEDLIVWMRTAALPTFRKLYGKID------TD 267
Q9SAK3_ARATH PKNFQKGAPIGGGTLN---ISKPLSEQEDLIVWMRTAALPTFRKLYGKIE------TD 249
Q653D8_ORYSA PKNFQNGTLIGGGQLN---PSKPLSEQEDLIVWMRIAALPTFRKLYGRID------MD 267
Q0DGI4_ORYSA PENFQKGGLIGGGQLN---EKLPLSEQEDLIVWMRTAALPTFRKLYGRIE------TD 238
Q10SJ9_ORYSA PSNFQKGSLIGGAKLN---ESIPLSEQEDLIVWMRTAALPTFRKLYGRIE------TD 252
Q1SP74_MEDTR PKNFQSGGLIGGAKLN---ESVPLSEQEDLIVWMRTAALPTFRKLYGKIE------SD 261
Q1T0V9_MEDTR PKNFQTGSLIGGARLN---ESIPLSEQEDLIVWMRTAALPTFRKLYGKIE------VD 240
Q67YS6_ARATH PINFQNGTLIGGAKLD---PKIPLSDQEDFIVWMRAAALLSFRKLYGRIE------ED 261
Q10CF0_ORYSA PFNFQNGSLIGGGKLD---PALPLNQQEDLIVWMRTAALPQFRKLYGVIE------ED 266
Q4Q5N2_LEIMA NTSATDPYLREGYYYKEPGHKIPLSTDEDLIVWLDPAFTSDVTKNYRILN------V 291
Q0P0L8_LEIDO NKSATDPYLREGYYYKEPGHKIPLSIDEDLIVWLDPAFTSDVTKNYRILN------V 291
Q4QHS2_LEIMA PYPTTNEYLRNGWYLHEPGHALPDPSDYDLHVWLRASLTSNFRKLYRIIN------M 458
Q4FWD0_LEIMA RMPSDNAYFNEGWYADEPGHRIPVTTDEDLMVWARVASLPKFRKLYRVID------E 340
:: * . . *
CC50A_HUMAN TLPAGRYSLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLL 344
CC50B_HUMAN GLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVML 336
Q8STD2_DROME GLKSGNYTLNIKYNYPVVSFDGTKRMILSTTSVLGGKNPFLGIAYIVVGAICITLGLALL 334
CC50C_HUMAN GLPAGNYSFNITYNFPVTRFHGEKSVVLSTLTWCGGNSLFLGLAYTVTGAMTWLASFAMM 337
Q19635_CAEEL GLPKGQYQLTINYNYPVDMYSGDKYFVIANENWVGPRNLFLPVIYLVVGTFLLLVTILFI 347
Q21844_CAEEL GLPQGTYILTVENNYPVQSFGGKKEFVISTTSWAGGKNSFLGIAYLVVGSLAIVLGVVFI 327
CDC50_YEAST SLPKGKYQMNIELNYPISLFGGTKSFVLTTNGAIGGRNMSLGVLYLIVAGLCALFGIIFL 351
YN8S_YEAST GLGKGIYIADIELNYPVRSFYGTKSFVLTTNSIIGAGNEALGIVYLIVAGIATLFAILFL 354
LEM3_YEAST TLPAGEYQLDIGLHWPVLEFNGKKGIYLTHGSHLGGRNPFLGIVYLIGGCICAAMALILL 393
Q655Y4_ORYSA LKKNDTITVKLSNNYNTYNFGGKKKLVLSTATWLGGKNDFLGFAYVIVGGVCFFLAFAFT 333
Q6H511_ORYSA LKKGDTITVTLENNYNTYSFSGKKKLVLSTSTWLGGKNDFLGLAYLSVGGLCFFLAFAFT 325
Q9LTW0_ARATH LEKGENIQVTLQNNYNTYSFSGKKKLVLSTTSWLGGKNDFLGIAYLTVGGICFVLALAFT 325
Q9SLK2_ARATH LEMGDTIHVKLNNNYNTYSFNGKKKLVLSTTSWLGGKNDFLGIAYLTVGGICFILALAFT 324
Q9SA35_ARATH LQAGDTIKVLLQNNYNTYSFNGKKKLVLSTTSWLGGRNDFLGIAYLTVGSICLFLAVSFS 327
Q9SAK3_ARATH LHAGDTITVLLQNNYNTYSFNGQKKLVLSTTSWLGGRNDFLGIAYLTVGSICLFLAVTFA 309
Q653D8_ORYSA LQAGDRVEVTMQNNYNSYSFNGKKSLVLSTAGWLGGKNAFLGRAYAIVGLACFLLALLLA 327
Q0DGI4_ORYSA IMASDEITVVIQNNYNTYSFGGTKALVLSTTSWIGGKNNFIGFAYVAIGTISFLIALAFV 298
Q10SJ9_ORYSA IMANDQLTVVIQNNYNTYSFGGSKALVLSTTSWIGGKNNFIGVAYLTIGGLCIFLAVGFV 312
Q1SP74_MEDTR LEVNDEIEILIQNNYNTYEFQGRKKLVLSTTTWIGGKNRFLGVAYLCVGGLSLFCAIGFI 321
Q1T0V9_MEDTR LEANDEITVVIENNYNTYQFGGTKSVILSTTTWIGGKNDFLGIAYILIGGLSLVYSLVFL 300
Q67YS6_ARATH LEPGKVVEVNLMNNYNTYSFSGQKKLILSTSNWLGGRNDFLGITYLVVGSSSIVISIIFM 321
Q10CF0_ORYSA LQADEIITMHIANNYNTYSFGGKKSLILTTSTWLGGKNDFLGYAYLITGSLSLFLTILFA 326
Q4Q5N2_LEIMA DLPAGDYYFEITEQYPTAPYASQKFVQLATRSWIGGRNHVLGSLLIIMGGMAFIIAVTLL 351
Q0P0L8_LEIDO DLPAGDYYFEITEQYPTAPYASHKFVQLATRSWIGGRSHVLGSLLIIMGGTAFIMAVTLL 351
Q4QHS2_LEIMA PLYPGTYLVEISEFYDVVSFRGRKSVVLQNANWVGGRNIVLGVVFIVMGCASFVLGVTFT 518
Q4FWD0_LEIMA DLVPGTYLMRIQEHFNAASYGGTKSFSLATLSWLGGRNTFMAWMYFTIGAVSAVSGASFL 400
: : : . * . : * . : . :
CC50A_HUMAN V-INHKYRNSSNTADITI------361
CC50B_HUMAN V-VYIRYQDQDDDDEE------351
Q8STD2_DROME F-IHMRCSRSNMEMINVNPHTQYS------357
CC50C_HUMAN A-IHIMLKNKKMSFFHQ------353
Q19635_CAEEL L-IWLKQ-----RLSRVHPT------361
Q21844_CAEEL V-IHMKFGHSMNELSNVSEIHH------348
CDC50_YEAST V-KLIFQPRAMGDHTYLNFDDEENEDYEDVHAENTTLREIL------391
YN8S_YEAST I-KVIFKPRPMHDHSYLNFENSDTP-FDESSVVSIPLREIL------393
LEM3_YEAST T-FWLFGGRKIADASSLSWNMK------414
Q655Y4_ORYSA L-LYLIKPRKLGDHNYLSWNRHPGGR------358
Q6H511_ORYSA L-LYLIKPRKMGDNNYLSWNRNPAGR------350
Q9LTW0_ARATH V-MYLVKPRRLGDPTYLSWNRIPGGR------350
Q9SLK2_ARATH I-MYLVKPRRLGDPSYLSWNRNPGGR------349
Q9SA35_ARATH V-LYLAKPRQLGDPSYLSWNRSAGGGR------353
Q9SAK3_ARATH V-LYLVKPRQLGDPSYLSWNRSAGGLQ------335
Q653D8_ORYSA L-LYFVFPMR---EEHLSLHYTPARLVR------351
Q0DGI4_ORYSA G-LNMVKPRYGKIARWIGFQGKLWSIDHGAT------328
Q10SJ9_ORYSA VLLYMVKPRTLGDPSYLSWNRDTPDRPN------340
Q1SP74_MEDTR L-LYVVKPRPLGDPSYLSWNRNPGILK------347
Q1T0V9_MEDTR L-MYLMKPRPLGDPRYLTWNKNSKCLN------326
Q67YS6_ARATH L-LHLKNPRPYGDN---SWNKKSLSS------343
Q10CF0_ORYSA L-IHVKNPRPHGDANYLSWNRPNSNS------351
Q4Q5N2_LEIMA SMKCLIMQGYTQ------363
Q0P0L8_LEIDO SVKYLIMPVYTEDI------365
Q4QHS2_LEIMA VECMLQLNGVNRYKRLREPKRSWYVFWPNEPEFANYYQLRLRRHIPMAQLQLLRKAVAEL 578
Q4FWD0_LEIMA CIHHWYGDRALRAVAMLLKGD------421
CC50A_HUMAN ------
CC50B_HUMAN ------
Q8STD2_DROME ------
CC50C_HUMAN ------
Q19635_CAEEL ------
Q21844_CAEEL ------
CDC50_YEAST ------
YN8S_YEAST ------
LEM3_YEAST ------
Q655Y4_ORYSA ------
Q6H511_ORYSA ------
Q9LTW0_ARATH ------
Q9SLK2_ARATH ------
Q9SA35_ARATH ------
Q9SAK3_ARATH ------
Q653D8_ORYSA ------
Q0DGI4_ORYSA ------
Q10SJ9_ORYSA ------
Q1SP74_MEDTR ------
Q1T0V9_MEDTR ------
Q67YS6_ARATH ------
Q10CF0_ORYSA ------
Q4Q5N2_LEIMA ------
Q0P0L8_LEIDO ------
Q4QHS2_LEIMA ESLTRDGDVNRNDVNGQRA 597
Q4FWD0_LEIMA ------