Supplementary MBBS I (First) Professional Examination 2015-16
Course Code: MBS103 Paper ID: S322208
Biochemistry -I
Time: 2 Hours 40 Minutes Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support your answer.
Part ‘B’
1. Briefly discuss the synthesis of thyroid hormones. What are the thyroid function tests? (6+4)
2. Write short notes on any six of the following: (5x6=30)
a) Uncouplers of oxidative phosphorylation
b) Competitive inhibition and its significance
c) 2,3-Bisphosphoglycerate and its significance
d) Carnitine shuttle
e) Important products derived from tyrosine
f) Transamination
g) Gibbs- Donnan membrane equilibrium
Supplementary MBBS I (First) Professional Examination 2015-16
Roll No. Student’s Name
Student’s Signature Invigilator’s Signature
Course Code:MBS103 Paper ID: S322208
Biochemistry - I
Part ‘A’
Time: 20 Minutes Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
Q.1 The following is a pseudo ketone body:
a) Acetoacetate
b) -hydroxybutyrate
c) Acetone
d) None of the above
Q.2 The end product of amino acid catabolism is:
a) Urea b) Creatine
c) Creatinine d) Uric acid
Q.3 The following is antagonistic to insulin:
a) Growth hormone
b) Epinephrine
c) Cortisol
d) All of the above
Q.4 The following is a non-essential amino acid:
a) Valine
b) Leucine
c) Isoleucine
d) Alanine
Q.5 Glutathione contains:
a) Cysteine
b) Glycine
c) Glutamate
d) All of the above
Q.6 Cardiac isoenzyme is:
a) CPK-1
b) CPK-2
c) CPK-3
d) None of the above
Q.7 Na/K – pump is an example of:
a) Facilitated diffusion
b) Primary active transport
c) Secondary active transport
d) Simple diffusion
Q.8 Cystic fibrosis affects the following channel:
a) Sodium b) Potassium
c) Chloride d) Calcium
Q.9 Bad cholesterol is:
a) HDL
b) VLDL
c) LDL
d) None of the above
Q.10 Phrenoderma is due to a deficiency of:
a) Essential amino acids
b) Essential fatty acids
c) Dietary fibres
d) Purines
Q.11 The precursor for gluconeogenesis is:
a) Alanine
b) Lactate
c) Glycerol
d) All of the above
P.T.O.
Q.12 Glucose-6phosphate dehydrogenase deficiency may result in:
a) Aplastic anemia
b) Nutritional anemia
c) Hemolytic anemia
d) Polycythemia
Q.13 Storage form of lipids is:
a) Phospholipid
b) Fatty acid
c) Cholesterol
d) Triacylglycerol
Q.14 Oxygen-dissociation curve of myoglobin is:
a) Rectangular hyperbola
b) Parabola
c) Sigmoid
d) Linear
Q.15 The following is an ‘activated amino acid’:
a) Glutamate
b) Asparagine
c) S-adenosyl methionine
d) Proline
Q.16 The following is a second messenger:
a) Ca
b) cAMP
c) Diacylglycerol
d) All of the above
Q.17 Adenosine is:
a) A nitrogenous base
b) A nucleoside
c) A nucleotide
d) A nucleic acid
Q.18 The following enzyme is used therapeutically:
a) Asparaginase
b) Hyaluronidase
c) Streptokinase
d) All of the above
Q.19 Deficiency of HGPRTase results in:
a) Gaucher’s disease
b) Hyperammonemia type I
c) Lesch-Nyhan syndrome
d) Alkaptonuria
Q.20 Fluoride inhibits:
a) Enolase
b) Pyruvate dehydrogenase
c) Fumarase
d) Glucokinase