Supplemental Table 1A: T1DGC Data Excluding HBDI Families

1

Supplemental Table 1a: T1DGC data excluding HBDI families

Allele / obs T1D freq % (n) / exp T1d freq % (n) / AFBAC freq % (n) / p value / OR (95%CI)
A*0101 / 17.1 (456) / 21.7 (217.1) / 16.4 (164) / 0.003 / 0.74(0.62 - 0.89)
A*0201 / 30 (802) / 25.5 (255.5) / 26.7 (267) / 0.025 / 1.25(1.06 - 1.47)
A*0205 / 2.4 (63) / 1.5 (15.4) / 1.5 (15) / 0.130 / 1.55(0.88 - 2.72)
A*0206 / 0.3 (7) / 0 (0) / 0.3 (3) / 0.106 / 0(0 - 0)
A*0301 / 12.2 (327) / 11.5 (114.6) / 13.0 (130) / 0.550 / 1.08(0.86 - 1.35)
A*0302 / 0.5 (14) / 0 (0) / 0.3 (3) / 0.022 / 0(0 - 0)
A*1101 / 3.6 (95) / 6.4 (63.7) / 7.2 (72) / 3.E-04 / 0.54(0.39 - 0.75)
A*2301 / 1.1 (30) / 1.6 (16.2) / 1.8 (18) / 0.227 / 0.69(0.37 - 1.26)
A*2402 / 11.5 (307) / 7 (69.8) / 7.9 (79) / 2.E-04 / 1.73(1.32 - 2.27)
A*2403 / 0.3 (7) / 0 (0) / 0.1 (1) / 0.106 / 0(0 - 0)
A*2501 / 2.5 (66) / 2.6 (25.9) / 2.9 (29) / 0.834 / 0.95(0.6 - 1.51)
A*2601 / 2.5 (66) / 2.7 (26.8) / 3.0 (30) / 0.721 / 0.92(0.58 - 1.45)
A*2901 / 0.3 (8) / 0 (0) / 0.3 (3) / 0.084 / 0(0 - 0)
A*2902 / 2.4 (63) / 2.4 (24.2) / 2.7 (27) / 0.917 / 0.98(0.61 - 1.57)
A*3001 / 0.8 (21) / 0.9 (9.2) / 1.0 (10) / 0.684 / 0.86(0.39 - 1.86)
A*3002 / 3.6 (95) / 3.8 (38) / 2.1 (21) / 0.723 / 0.93(0.63 - 1.37)
A*3101 / 1.9 (51) / 1.8 (18) / 2.0 (20) / 0.833 / 1.06(0.62 - 1.83)
A*3201 / 2.2 (58) / 4.3 (42.8) / 4.1 (41) / 0.001 / 0.5(0.33 - 0.74)
A*3301 / 1 (26) / 1.1 (11) / 1.2 (12) / 0.736 / 0.88(0.43 - 1.79)
A*3303 / 0.5 (14) / 0.5 (4.7) / 0.4 (4) / 0.826 / 1.12(0.39 - 3.2)
A*3601 / 0 (1) / 0 (0) / 0.1 (1) / 0.541 / 0(0 - 0)
A*6601 / 0.1 (3) / 0.6 (5.7) / 0.6 (6) / 0.011 / 0.19(0.05 - 0.78)
A*6801 / 2.5 (67) / 3 (29.6) / 2.3 (23) / 0.450 / 0.84(0.54 - 1.31)
A*6802 / 0.2 (5) / 1.2 (11.9) / 1.3 (13) / 7.E-05 / 0.16(0.06 - 0.45)
B*0702 / 6.5 (174) / 11.6 (116) / 14.6 (146) / 9.9E-07 / 0.53(0.41 - 0.68)
B*0705 / 0.7 (18) / 0 (0) / 0.3 (3) / 0.009 / 0(0 - 0)
B*0801 / 20.8 (556) / 22.9 (229) / 11.5 (115) / 0.219 / 0.88(0.74 - 1.05)
B*1302 / 2 (53) / 1.7 (17) / 2.1 (21) / 0.586 / 1.17(0.67 - 2.02)
B*1401 / 0.1 (3) / 0.4 (4.4) / 0.5 (5) / 0.051 / 0.25(0.06 - 1.1)
B*1402 / 1.9 (51) / 2.2 (21.8) / 2.7 (27) / 0.604 / 0.87(0.53 - 1.45)
B*1501 / 12.2 (326) / 9.2 (92.4) / 4.5 (45) / 0.018 / 1.36(1.07 - 1.74)
B*1509 / 0.1 (2) / 0 (0) / 0.1 (1) / 0.387 / 0(0 - 0)
B*1516 / 0 (1) / 0 (0) / 0.1 (1) / 0.541 / 0(0 - 0)
B*1517 / 0.4 (11) / 0 (0) / 0.3 (3) / 0.043 / 0(0 - 0)
B*1518 / 0.2 (5) / 0 (0) / 0.2 (2) / 0.171 / 0(0 - 0)
B*1801 / 10.6 (284) / 6 (60.4) / 7.1 (71) / 5.5E-05 / 1.85(1.39 - 2.47)
B*2702 / 0.3 (9) / 0 (0) / 0.3 (3) / 0.067 / 0(0 - 0)
B*2703 / 3 (81) / 4 (40.4) / 3.3 (33) / 0.134 / 0.74(0.51 - 1.09)
B*2707 / 0 (1) / 0 (0) / 0.2 (2) / 0.541 / 0(0 - 0)
B*3501 / 3.7 (99) / 4.8 (47.9) / 6.0 (60) / 0.142 / 0.77(0.54 - 1.09)
B*3502 / 0.3 (9) / 1 (9.9) / 1.2 (12) / 0.014 / 0.34(0.14 - 0.84)
B*3503 / 1.7 (46) / 1.1 (11.5) / 1.4 (14) / 0.218 / 1.51(0.79 - 2.89)
B*3508 / 0.3 (7) / 0.4 (3.6) / 0.4 (4) / 0.634 / 0.73(0.2 - 2.61)
B*3701 / 0.7 (18) / 1 (9.9) / 1.2 (12) / 0.326 / 0.67(0.31 - 1.47)
B*3801 / 1.9 (50) / 1.9 (19.4) / 2.4 (24) / 0.890 / 0.96(0.57 - 1.63)
B*3901 / 1.2 (31) / 1.1 (10.7) / 1.3 (13) / 0.820 / 1.09(0.54 - 2.18)
B*3906 / 2.8 (75) / 0.4 (3.6) / 0.4 (4) / 6.3E-06 / 8.08(2.79 - 23.45)
B*4001 / 5.2 (138) / 3.5 (35.1) / 3.5 (35) / 0.040 / 1.5(1.03 - 2.18)
B*4002 / 0.6 (15) / 1.4 (13.9) / 1.7 (17) / 0.012 / 0.4(0.19 - 0.83)
B*4006 / 0.1 (2) / 0 (0) / 0.3 (3) / 0.387 / 0(0 - 0)
B*4101 / 1 (27) / 0 (0) / 0.2 (2) / 0.001 / 0(0 - 0)
B*4102 / 0.1 (2) / 0.4 (3.6) / 0.4 (4) / 0.051 / 0.2(0.03 - 1.11)
B*4402 / 5.8 (155) / 6.9 (68.5) / 8.6 (86) / 0.249 / 0.84(0.62 - 1.12)
B*4403 / 1.9 (50) / 4.1 (40.8) / 5.1 (51) / 1.5E-04 / 0.45(0.29 - 0.68)
B*4405 / 0.3 (7) / 0 (0) / 0.1 (1) / 0.106 / 0(0 - 0)
B*4501 / 0.5 (14) / 0.6 (5.9) / 0.7 (7) / 0.796 / 0.87(0.33 - 2.29)
B*4701 / 0.3 (7) / 0.4 (3.6) / 0.4 (4) / 0.634 / 0.73(0.2 - 2.61)
B*4801 / 0 (1) / 0 (0) / 0.1 (1) / 0.541 / 0(0 - 0)
B*4901 / 2.5 (68) / 1 (9.9) / 1.2 (12) / 0.004 / 2.61(1.33 - 5.1)
B*5001 / 2.5 (67) / 1.4 (13.7) / 1.3 (13) / 0.039 / 1.85(1.03 - 3.33)
B*5101 / 3.1 (83) / 3.5 (35.2) / 4.4 (44) / 0.527 / 0.88(0.59 - 1.31)
B*5108 / 0 (1) / 0 (0) / 0.1 (1) / 0.541 / 0(0 - 0)
B*5201 / 0.4 (10) / 1.1 (11.5) / 1.4 (14) / 0.006 / 0.32(0.14 - 0.75)
B*5301 / 0.2 (4) / 0.5 (4.8) / 0.5 (5) / 0.072 / 0.31(0.08 - 1.19)
B*5501 / 0.9 (25) / 1.4 (13.9) / 1.7 (17) / 0.237 / 0.68(0.35 - 1.31)
B*5601 / 0.6 (16) / 0 (0) / 0.3 (3) / 0.014 / 0(0 - 0)
B*5701 / 0.5 (14) / 2.5 (25) / 3.1 (31) / 2.4E-07 / 0.2(0.11 - 0.39)
B*5801 / 1.1 (28) / 1.7 (16.9) / 1.4 (14) / 0.118 / 0.62(0.34 - 1.14)
B*7301 / 0.3 (9) / 0 (0) / 0.1 (1) / 0.067 / 0(0 - 0)
C*0102 / 1.8 (47) / 2.9 (28.8) / 3.5 (35) / 0.036 / 0.6(0.38 - 0.97)
C*0202 / 4 (107) / 3.8 (37.7) / 4.1 (41) / 0.751 / 1.06(0.73 - 1.55)
C*0302 / 0.4 (11) / 0.7 (7.1) / 0.5 (5) / 0.258 / 0.58(0.22 - 1.5)
C*0303 / 5.4 (143) / 3.4 (34.4) / 3.9 (39) / 0.019 / 1.58(1.08 - 2.32)
C*0304 / 13.4 (357) / 9.6 (95.5) / 5.7 (57) / 0.004 / 1.46(1.15 - 1.85)
C*0401 / 6 (161) / 9.1 (91.2) / 11.2 (112) / 0.001 / 0.64(0.49 - 0.84)
C*0501 / 11.2 (299) / 8 (80.3) / 9.7 (97) / 0.008 / 1.44(1.12 - 1.87)
C*0602 / 6.5 (173) / 6.8 (68.5) / 8.4 (84) / 0.691 / 0.94(0.7 - 1.26)
C*0701 / 25.8 (689) / 25.7 (257.1) / 15.7 (157) / 0.977 / 1(0.85 - 1.19)
C*0702 / 10 (266) / 12.4 (124.4) / 15.3 (153) / 0.039 / 0.78(0.62 - 0.98)
C*0704 / 1.1 (29) / 1.5 (15) / 1.8 (18) / 0.307 / 0.72(0.39 - 1.36)
C*0801 / 0.2 (4) / 0 (0) / 0.2 (2) / 0.221 / 0(0 - 0)
C*0802 / 2 (53) / 2.6 (25.5) / 3.1 (31) / 0.292 / 0.77(0.48 - 1.24)
C*1202 / 0.4 (10) / 1 (10.1) / 1.2 (12) / 0.020 / 0.36(0.15 - 0.87)
C*1203 / 6.1 (163) / 5.7 (57.1) / 7.0 (70) / 0.673 / 1.07(0.79 - 1.46)
C*1402 / 0.8 (21) / 0.9 (9.3) / 1.1 (11) / 0.663 / 0.85(0.39 - 1.84)
C*1502 / 1.5 (40) / 1.8 (18.2) / 2.2 (22) / 0.483 / 0.82(0.47 - 1.43)
C*1504 / 0.2 (6) / 0 (0) / 0.2 (2) / 0.134 / 0(0 - 0)
C*1505 / 0.8 (21) / 0.4 (3.6) / 0.4 (4) / 0.166 / 2.18(0.71 - 6.63)
C*1601 / 1.2 (33) / 2.6 (26.3) / 3.2 (32) / 0.003 / 0.46(0.28 - 0.78)
C*1602 / 0.4 (10) / 0 (0) / 0.3 (3) / 0.053 / 0(0 - 0)
C*1604 / 0.2 (4) / 0.4 (4.5) / 0.5 (5) / 0.096 / 0.34(0.09 - 1.3)
C*1701 / 0.8 (22) / 0.5 (5.3) / 0.6 (6) / 0.354 / 1.56(0.6 - 4.05)
C*1801 / 0 (1) / 0 (0) / 0.1 (1) / 0.541 / 0(0 - 0)

Supplemental Table 1b. Data from HBDI families included in T1DGC data set.

obs T1D freq % (n) / exp T1D freq* % (n) / AFBAC freq % (n) / p value / OR (95%CI)
A*0101 / 19.7 (165) / 22.3 (130.7) / 15.8 (92) / 0.400 / 0.85 (0.66 - 1.11)
A*0201 / 32.5 (272) / 26.2 (153.4) / 29.3 (171) / 0.017 / 1.35 (1.07 - 1.71)
A*0205 / 1.2 (10) / 0.7 (4) / 0.7 (4) / 0.323 / 1.73 (0.54 - 5.52)
A*0301 / 10.8 (90) / 11.8 (69.3) / 13.2 (77) / 0.660 / 0.9 (0.64 - 1.25)
A*0302 / 0.2 (2) / 0 (0) / 0.2 (1) / 0.231 / 0 (0 - 0)
A*1101 / 2.9 (24) / 5.7 (33.6) / 6.3 (37) / 0.011 / 0.49 (0.28 - 0.83)
A*2301 / 1.6 (13) / 1.8 (10.3) / 1.9 (11) / 0.814 / 0.88 (0.39 - 2.01)
A*2402 / 10.9 (91) / 6.8 (39.8) / 7.5 (44) / 0.008 / 1.67 (1.13 - 2.46)
A*2501 / 1.7 (14) / 2.1 (12.1) / 2.2 (13) / 0.639 / 0.81 (0.37 - 1.75)
A*2601 / 2.9 (24) / 2.2 (13) / 2.4 (14) / 0.409 / 1.3 (0.66 - 2.58)
A*2901 / 0.5 (4) / 0.5 (3.2) / 0.5 (3) / 0.902 / 0.89 (0.2 - 3.91)
A*2902 / 2 (17) / 4.2 (24.6) / 4.6 (27) / 0.024 / 0.47 (0.25 - 0.89)
A*3001 / 0.5 (4) / 1.1 (6.7) / 1.2 (7) / 0.165 / 0.41 (0.12 - 1.44)
A*3002 / 2.6 (22) / 1.5 (9) / 1.0 (6) / 0.152 / 1.72 (0.79 - 3.77)
A*3101 / 2.8 (23) / 3.4 (19.9) / 1.7 (10) / 0.541 / 0.8 (0.44 - 1.48)
A*3201 / 1.8 (15) / 4 (23.7) / 4.5 (26) / 0.014 / 0.43 (0.22 - 0.83)
A*3301 / 0.1 (1) / 0.9 (5.4) / 0.7 (4) / 0.029 / 0.13 (0.02 - 1.09)
A*6801 / 2.9 (24) / 3.4 (19.6) / 3.4 (20) / 0.667 / 0.85 (0.46 - 1.56)
A*6802 / 1.1 (9) / 1.1 (6.7) / 1.2 (7) / 0.938 / 0.94 (0.34 - 2.57)
B*0702 / 8.4 (70) / 11.5 (67.2) / 14.9 (87) / 0.088 / 0.7 (0.5 - 1)
B*0705 / 1 (8) / 0 (0) / 0.2 (1) / 0.017 / 0 (0 - 0)
B*0801 / 21.4 (179) / 18.8 (110.2) / 9.9 (58) / 0.205 / 1.17 (0.9 - 1.53)
B*1302 / 1.3 (11) / 1.4 (8.1) / 1.7 (10) / 0.963 / 0.96 (0.38 - 2.39)
B*1401 / 0.6 (5) / 0.6 (3.5) / 0.7 (4) / 0.956 / 1.02 (0.26 - 4.02)
B*1402 / 1.1 (9) / 1.9 (11.1) / 2.4 (14) / 0.220 / 0.56 (0.23 - 1.37)
B*1501 / 12.7 (106) / 10.1 (58.9) / 4.5 (26) / 0.114 / 1.3 (0.93 - 1.82)
B*1503 / 0.1 (1) / 0 (0) / 0.2 (1) / 0.397 / 0 (0 - 0)
B*1517 / 0.5 (4) / 0 (0) / 0.2 (1) / 0.090 / 0 (0 - 0)
B*1518 / 0.1 (1) / 0.5 (2.7) / 0.5 (3) / 0.226 / 0.26 (0.03 - 2.59)
B*1801 / 8.7 (73) / 3.9 (22.6) / 5.0 (29) / 3.E-04 / 2.38 (1.46 - 3.86)
B*2703 / 3.8 (32) / 3.2 (18.7) / 2.7 (16) / 0.483 / 1.2 (0.67 - 2.15)
B*3501 / 3.2 (27) / 5.3 (31.1) / 6.8 (40) / 0.070 / 0.6 (0.35 - 1.01)
B*3502 / 0.4 (3) / 1.5 (8.8) / 1.9 (11) / 0.022 / 0.24 (0.06 - 0.88)
B*3503 / 1.2 (10) / 1.2 (7.3) / 1.5 (9) / 0.971 / 0.96 (0.37 - 2.51)
B*3508 / 0.6 (5) / 0.6 (3.5) / 0.7 (4) / 0.956 / 1.02 (0.26 - 4.02)
B*3701 / 0.6 (5) / 0.6 (3.5) / 0.7 (4) / 0.956 / 1.02 (0.26 - 4.02)
B*3801 / 1.6 (13) / 2.6 (15) / 2.7 (16) / 0.205 / 0.6 (0.28 - 1.27)
B*3901 / 1.3 (11) / 0.9 (5) / 1.0 (6) / 0.389 / 1.56 (0.54 - 4.52)
B*3906 / 4.3 (36) / 0.3 (1.6) / 0.3 (2) / 3.E-06 / 16.75 (3.37 - 83.12)
B*4001 / 7.2 (60) / 8 (46.9) / 5.8 (34) / 0.659 / 0.89 (0.6 - 1.32)
B*4002 / 0.6 (5) / 1.1 (6.5) / 1.4 (8) / 0.304 / 0.53 (0.17 - 1.72)
B*4101 / 0.8 (7) / 0.3 (1.9) / 0.3 (2) / 0.221 / 2.56 (0.52 - 12.66)
B*4402 / 6.8 (57) / 7.5 (44.2) / 9.8 (57) / 0.703 / 0.9 (0.6 - 1.35)
B*4403 / 2.3 (19) / 5.3 (31.1) / 6.8 (40) / 0.004 / 0.41 (0.23 - 0.74)
B*4701 / 0.4 (3) / 0.3 (1.9) / 0.3 (2) / 0.905 / 1.09 (0.18 - 6.69)
B*4901 / 1.1 (9) / 0.7 (4.2) / 0.9 (5) / 0.466 / 1.5 (0.47 - 4.81)
B*5001 / 1 (8) / 0.9 (5.5) / 1.0 (6) / 0.930 / 1.03 (0.34 - 3.06)
B*5101 / 2.5 (21) / 3.1 (18) / 3.9 (23) / 0.577 / 0.81 (0.43 - 1.53)
B*5201 / 0.2 (2) / 0.6 (3.5) / 0.7 (4) / 0.308 / 0.41 (0.07 - 2.32)
B*5301 / 0.1 (1) / 0.5 (2.7) / 0.5 (3) / 0.226 / 0.26 (0.03 - 2.59)
B*5501 / 0.6 (5) / 1.2 (7.3) / 1.5 (9) / 0.211 / 0.48 (0.15 - 1.5)
B*5601 / 0.5 (4) / 1.2 (6.8) / 1.2 (7) / 0.157 / 0.41 (0.12 - 1.41)
B*5701 / 0.6 (5) / 3.3 (19.6) / 4.3 (25) / 1.E-04 / 0.17 (0.07 - 0.47)
B*5703 / 0.1 (1) / 0.3 (1.9) / 0.3 (2) / 0.404 / 0.36 (0.03 - 4.08)
B*5801 / 0.4 (3) / 0.7 (4.3) / 0.7 (4) / 0.356 / 0.49 (0.11 - 2.17)
C*0102 / 2.6 (22) / 2.1 (12.2) / 2.2 (13) / 0.471 / 1.27 (0.62 - 2.57)
C*0202 / 3.5 (29) / 3.7 (21.9) / 4.8 (28) / 0.860 / 0.93 (0.53 - 1.63)
C*0206 / 0.1 (1) / 0 (0) / 0.2 (1) / 0.397 / 0 (0 - 0)
C*0302 / 0.1 (1) / 0.3 (1.9) / 0.3 (2) / 0.403 / 0.36 (0.03 - 4.06)
C*0303 / 6.1 (51) / 4.7 (27.3) / 3.9 (23) / 0.213 / 1.33 (0.83 - 2.15)
C*0304 / 14.1 (118) / 14.6 (85.6) / 8.2 (48) / 0.938 / 0.96 (0.71 - 1.3)
C*0401 / 6.1 (51) / 9.5 (55.7) / 12.3 (72) / 0.029 / 0.62 (0.42 - 0.92)
C*0501 / 11.7 (98) / 7 (41.1) / 9.1 (53) / 0.003 / 1.76 (1.2 - 2.58)
C*0602 / 4.2 (35) / 6.5 (38) / 8.4 (49) / 0.075 / 0.63 (0.39 - 1.01)
C*0701 / 25.3 (211) / 22.4 (130.8) / 13.9 (81) / 0.187 / 1.17 (0.92 - 1.51)
C*0702 / 13.4 (112) / 12.4 (72.6) / 16.1 (94) / 0.497 / 1.09 (0.8 - 1.5)
C*0704 / 0.6 (5) / 1.6 (9.6) / 2.1 (12) / 0.063 / 0.36 (0.12 - 1.07)
C*0802 / 1.6 (13) / 2.6 (15) / 3.3 (19) / 0.209 / 0.6 (0.29 - 1.28)
C*1202 / 0.2 (2) / 0.7 (4.2) / 0.9 (5) / 0.187 / 0.33 (0.06 - 1.79)
C*1203 / 4.4 (37) / 4.3 (25) / 5.5 (32) / 0.813 / 1.04 (0.62 - 1.75)
C*1402 / 0.5 (4) / 1.1 (6.5) / 1.4 (8) / 0.185 / 0.43 (0.12 - 1.49)
C*1502 / 1.2 (10) / 2 (11.5) / 1.7 (10) / 0.275 / 0.61 (0.26 - 1.43)
C*1505 / 0.7 (6) / 0 (0) / 0.2 (1) / 0.038 / 0 (0 - 0)
C*1601 / 1.2 (10) / 3.7 (21.9) / 4.8 (28) / 0.002 / 0.31 (0.15 - 0.67)
C*1701 / 0.6 (5) / 0.7 (4.2) / 0.9 (5) / 0.805 / 0.83 (0.23 - 3.04)

Supplemental Table 2. LD adjustment all samples

Obs T1D freq % / exp T1D freq % / p< / 95% CI
A*0101 / 17.71 / 21.89 / 0.002 / 0.77 (0.66 - 0.88)
A*0201 / 30.63 / 24.70 / 3.E-04 / 1.35 (1.17 - 1.54)
A*0205 / 2.08 / 1.42 / 0.11 / 1.48 (0.91 - 2.38)
A*0206 / 0.26 / 0.20 / 0.69 / 1.32 (0.36 - 4.78)
A*0301 / 11.89 / 11.71 / 0.87 / 1.02 (0.84 - 1.22)
A*0302 / 0.46 / 0.33 / 0.52 / 1.39 (0.51 - 3.72)
A*1101 / 3.39 / 6.18 / 8.E-06 / 0.53 (0.40 - 0.70)
A*2301 / 1.23 / 1.67 / 0.21 / 0.73 (0.45 - 1.19)
A*2402 / 11.35 / 6.97 / 5.E-06 / 1.71 (1.37 - 2.12)
A*2403 / 0.29 / 0.15 / 0.37 / 1.91 (0.46 - 7.77)
A*2501 / 2.28 / 2.40 / 0.79 / 0.95 (0.64 - 1.40)
A*2601 / 2.57 / 2.59 / 0.96 / 0.99 (0.68 - 1.44)
A*2901 / 0.34 / 0.37 / 0.89 / 0.93 (0.34 - 2.49)
A*2902 / 2.25 / 3.07 / 0.09 / 0.73 (0.50 - 1.04)
A*3001 / 0.71 / 0.99 / 0.31 / 0.72 (0.38 - 1.35)
A*3002 / 3.34 / 2.89 / 0.41 / 1.16 (0.82 - 1.64)
A*3004 / 0.06 / 0.08 / 0.76 / 0.74 (0.08 - 6.84)
A*3101 / 2.11 / 2.49 / 0.40 / 0.84 (0.57 - 1.24)
A*3201 / 2.08 / 3.82 / 4.E-04 / 0.54 (0.37 - 0.75)
A*3301 / 0.77 / 0.93 / 0.55 / 0.82 (0.43 - 1.55)
A*3303 / 0.40 / 0.25 / 0.41 / 1.6 (0.52 - 4.86)
A*3402 / 0.17 / 0.08 / 0.43 / 2.11 (0.31 - 14.2)
A*3601 / 0.03 / 0.17 / 0.08 / 0.18 (0.01 - 1.74)
A*6601 / 0.09 / 0.57 / 9.E-04 / 0.16 (0.04 - 0.57)
A*6801 / 2.57 / 2.93 / 0.46 / 0.87 (0.61 - 1.25)
A*6802 / 0.40 / 1.16 / 0.002 / 0.34 (0.17 - 0.69)
B*0702 / 6.96 / 11.43 / 3.E-07 / 0.58 (0.47 - 0.70)
B*0705 / 0.74 / 0.22 / 0.023 / 3.42 (1.11 - 10.5)
B*0801 / 20.95 / 20.82 / 0.93 / 1.01 (0.87 - 1.16)
B*1302 / 1.82 / 1.54 / 0.47 / 1.19 (0.74 - 1.89)
B*1401 / 0.23 / 0.44 / 0.19 / 0.52 (0.18 - 1.42)
B*1402 / 1.71 / 2.03 / 0.43 / 0.84 (0.54 - 1.29)
B*1501 / 12.31 / 9.35 / 0.004 / 1.36 (1.11 - 1.65)
B*1503 / 0.14 / 0.07 / 0.49 / 2 (0.25 - 15.6)
B*1509 / 0.06 / 0.07 / 0.86 / 0.86 (0.08 - 8.73)
B*1516 / 0.03 / 0.07 / 0.50 / 0.43 (0.02 - 6.39)
B*1517 / 0.43 / 0.22 / 0.25 / 1.98 (0.61 - 6.38)
B*1518 / 0.17 / 0.27 / 0.46 / 0.62 (0.18 - 2.15)
B*1801 / 10.18 / 5.25 / 3.E-08 / 2.05 (1.59 - 2.61)
B*2702 / 0.26 / 0.32 / 0.70 / 0.82 (0.27 - 2.42)
B*2703 / 3.22 / 3.48 / 0.63 / 0.92 (0.66 - 1.27)
B*2707 / 0.03 / 0.12 / 0.19 / 0.24 (0.02 - 2.67)
B*3501 / 3.59 / 4.92 / 0.028 / 0.72 (0.53 - 0.96)
B*3502 / 0.34 / 1.15 / 5.E-04 / 0.29 (0.14 - 0.60)
B*3503 / 1.60 / 1.17 / 0.24 / 1.38 (0.81 - 2.33)
B*3508 / 0.34 / 0.42 / 0.67 / 0.81 (0.31 - 2.09)
B*3701 / 0.66 / 0.81 / 0.55 / 0.82 (0.41 - 1.61)
B*3801 / 1.80 / 2.29 / 0.25 / 0.78 (0.51 - 1.18)
B*3901 / 1.20 / 0.96 / 0.45 / 1.26 (0.69 - 2.27)
B*3906 / 3.19 / 0.32 / 4.E-10 / 10.31 (4.21 - 25.1)
B*4001 / 5.64 / 5.02 / 0.38 / 1.13 (0.86 - 1.47)
B*4002 / 0.54 / 1.20 / 0.012 / 0.45 (0.23 - 0.84)
B*4006 / 0.09 / 0.17 / 0.40 / 0.53 (0.10 - 2.71)
B*4101 / 0.97 / 0.22 / 0.004 / 4.49 (1.48 - 13.6)
B*4102 / 0.06 / 0.32 / 0.020 / 0.19 (0.03 - 0.96)
B*4402 / 5.99 / 7.03 / 0.17 / 0.84 (0.66 - 1.06)
B*4403 / 1.94 / 4.49 / 4.E-07 / 0.42 (0.30 - 0.59)
B*4405 / 0.20 / 0.05 / 0.22 / 3.68 (0.39 - 34.4)
B*4501 / 0.48 / 0.37 / 0.56 / 1.32 (0.51 - 3.38)
B*4701 / 0.29 / 0.47 / 0.29 / 0.61 (0.23 - 1.57)
B*4801 / 0.06 / 0.05 / 0.97 / 1.1 (0.08 - 13.7)
B*4901 / 2.19 / 0.86 / 0.001 / 2.6 (1.45 - 4.63)
B*5001 / 2.14 / 0.96 / 0.003 / 2.27 (1.30 - 3.94)
B*5002 / 0.06 / 0.07 / 0.86 / 0.86 (0.08 - 8.73)
B*5101 / 2.96 / 3.30 / 0.52 / 0.89 (0.63 - 1.25)
B*5107 / 0.03 / 0.07 / 0.50 / 0.43 (0.02 - 6.39)
B*5108 / 0.11 / 0.07 / 0.65 / 1.57 (0.19 - 12.8)
B*5201 / 0.34 / 0.91 / 0.009 / 0.37 (0.17 - 0.80)
B*5301 / 0.14 / 0.42 / 0.055 / 0.33 (0.10 - 1.06)
B*5501 / 0.86 / 1.30 / 0.14 / 0.66 (0.37 - 1.15)
B*5601 / 0.57 / 0.71 / 0.56 / 0.8 (0.38 - 1.67)
B*5701 / 0.54 / 2.77 / 4.E-11 / 0.19 (0.11 - 0.32)
B*5703 / 0.03 / 0.27 / 0.013 / 0.11 (0.01 - 0.96)
B*5801 / 0.88 / 1.11 / 0.44 / 0.79 (0.43 - 1.42)
B*7301 / 0.26 / 0.07 / 0.17 / 3.72 (0.51 - 26.7)
C*0102 / 1.97 / 2.43 / 0.29 / 0.81 (0.54 - 1.20)
C*0202 / 3.88 / 3.64 / 0.69 / 1.07 (0.78 - 1.46)
C*0206 / 0.03 / 0.07 / 0.49 / 0.42 (0.02 - 6.16)
C*0302 / 0.34 / 0.37 / 0.86 / 0.91 (0.33 - 2.43)
C*0303 / 5.53 / 3.80 / 0.010 / 1.48 (1.10 - 1.99)
C*0304 / 13.51 / 11.60 / 0.078 / 1.19 (0.99 - 1.42)
C*0401 / 6.04 / 9.26 / 6.E-05 / 0.63 (0.50 - 0.78)
C*0501 / 11.32 / 7.55 / 9.E-05 / 1.56 (1.26 - 1.93)
C*0602 / 5.93 / 6.70 / 0.30 / 0.88 (0.68 - 1.11)
C*0701 / 25.66 / 24.32 / 0.38 / 1.07 (0.93 - 1.23)
C*0702 / 10.78 / 12.37 / 0.12 / 0.86 (0.71 - 1.02)
C*0704 / 0.97 / 1.53 / 0.08 / 0.63 (0.37 - 1.06)
C*0801 / 0.14 / 0.13 / 0.89 / 1.1 (0.21 - 5.65)
C*0802 / 1.88 / 2.54 / 0.13 / 0.74 (0.49 - 1.09)
C*1202 / 0.34 / 0.87 / 0.014 / 0.39 (0.17 - 0.83)
C*1203 / 5.70 / 5.14 / 0.43 / 1.11 (0.85 - 1.45)
C*1402 / 0.71 / 1.35 / 0.027 / 0.52 (0.29 - 0.93)
C*1502 / 1.43 / 1.72 / 0.43 / 0.83 (0.51 - 1.32)
C*1504 / 0.23 / 0.13 / 0.45 / 1.81 (0.38 - 8.48)
C*1505 / 0.77 / 0.28 / 0.039 / 2.78 (1.01 - 7.62)
C*1601 / 1.20 / 3.04 / 5.E-06 / 0.39 (0.25 - 0.58)
C*1602 / 0.48 / 0.17 / 0.10 / 2.75 (0.77 - 9.80)
C*1604 / 0.11 / 0.33 / 0.10 / 0.34 (0.09 - 1.24)
C*1701 / 0.77 / 0.58 / 0.46 / 1.33 (0.62 - 2.81)
C*1801 / 0.03 / 0.07 / 0.49 / 0.42 (0.02 - 6.16)

©2010 American Diabetes Association. Published online at