Supplementary material
Appendix 1. Medline search strategy.
1 marijuana smoking.mp. or exp Marijuana Smoking/ (4372)
2 exp Cannabis/ or exp Cannabinoids/ or cannabi*.mp. (34069)
3 cannabinoid receptor agonists.mp. or exp Cannabinoid Receptor Agonists/ (7789)
4 sativex.mp. (127)
5 nabiximols.mp. (45)
6 exp Dronabinol/ (6743)
7 tetrahydrocannabinol.mp. (6092)
8 THC.mp. (5675)
9 exp Cannabidiol/ (1017)
10 CBD.mp. (4771)
11 nabilone.mp. (260)
12 quality-adjusted life year.mp. or exp Quality-Adjusted Life Years/ (11373)
13 Cost-benefit analysis.mp. or exp Cost-Benefit Analysis/ (73956)
14 incremental cost-effectiveness ratio.mp. (3262)
15 ICER.mp. (2288)
16 QALY.mp. (5660)
17 Health care costs.mp. or exp Health Care Costs/ (64678)
18 cost-effect*.mp. (92173)
19 economic evaluation.mp. (6485)
20 quality adjusted survival.mp. (364)
21 exp "Costs and Cost Analysis"/ec [Economics] (3637)
22 (cost$ adj benefit$).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier] (77706)
23 (benefit$ adj cost$).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier] (1172)
24 health-related quality of life.mp. (28852)
25 wellbeing.mp. (7575)
26 willingness to pay.mp. (3127)
27 patient preference.mp. or exp Patient Preference/ (8058)
28 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 (41096)
29 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 (232174)
30 28 and 29 (236)
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Appendix 2
Reasons for exclusion of 122 full text articles
· Not economic outcomes (i.e. no utility-based HRQoL data, resource use, costs, economic outcomes) or not a cannabis-based medicine intervention (n=28)
· Not a primary study (i.e. editorial, review, or opinion piece) or not an economic study (i.e. not an evaluation, costing study, willingness to pay study) (n=80)
· Unable to locate full text through interlibrary loans and/or contacting authors (n=9)
· Not peer reviewed (n=5)
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