Biographical Sketch: Thomas J. Inzana
Virginia Polytechnic Institute and State University, Life Sciences 1, Washington St, Blacksburg, VA 24061
Telephone: (540) 231-5188 - Email:
Professional preparation
State University of New York at AlfredA.A.S., Agricultural Science1973
University of GeorgiaB.S., Microbiology1975
University of GeorgiaM.S., Medical Microbiology1978
University of RochesterPh.D., Microbiology1982
Baylor College of MedicinePostdoctoral training,1982-84
Fellowship in Medical Laboratory
Microbiology and Public Health
Specialty Board CertificationDiplomate of the American Board of Medical and
Molecular Microbiology and Public Health
Appointments
7/10-present7/07-6/10 Associate Vice-President for Research Programs and Research Integrity Officer, Virginia Tech
10/06-05/07 / Tyler J. and Frances F. Young Professor of Bacteriology and University Research Integrity Officer, Virginia Tech
Associate Vice-President for Research Programs and Research Integrity Officer, Virginia Tech
Interim Associate Vice-President for Research Development, Virginia Tech
2003-present / Tyler J. and Frances F. Young Professor of Bacteriology, Virginia Tech
1996-present / Professor and Director, Clinical Microbiology, VA-MD Regional College of Veterinary Medicine (VMRCVM), Department of Biomedical Science and Pathobiology, Virginia Tech
1998-2002 / Director, Center for Molecular Medicine and Infectious Diseases, VMRCVM
2000 / Visiting Professor, University of Pennsylvania School of Medicine.
1991-96 / Associate Professor and Director, Clinical Microbiology, VMRCBM, Department of Biomedical Sciences and Pathobiology, Virginia Tech
1992 / Visiting Associate Professor, SUNY at Buffalo School of Medicine.
1987-91 / Assistant Professor and Director, Clinical Microbiology, VMRCVM, Department of Biomedical Sciences and Pathobiology, Virginia Tech
1984-87 / Assistant Professor and Assistant Director, Washington Animal Dis. Diagnosis Lab, Department of Veterinary Microbiology and Pathology, Washington State University
Publications
Five most relevant publications
Bandara, A.B., A. Champion, X. Wang, G. Berg, M.A. Apicella, M. McLendon, P. Azadi, D.S. Snyder, and T.J. Inzana. 2011. Characterization and Mutagenesis of a Capsule-Like Complex from Francisella tularensis LVS. PLoS ONE. 6(4): e19003
Sandal, I., J.Q. Shao, S. Annadata, M.A. Apicella, M. Boye, T.K. Jensen, G.K. Saunders, and T.J. Inzana. 2009. Histophilus somni biofilm formation in cardiopulmonary tissue of the bovine host following respiratory challenge.Microbes Infect. 11:254-263.
Sandal, I., J.Q. Shao, S. Annadata, M.A. Apicella, M. Boye, T.K. Jensen, G.K. Saunders, and T.J. Inzana. 2009. Histophilus somni biofilm formation in cardiopulmonary tissue of the bovine host following respiratory challenge.Microbes Infect. 11:254-263.
Li, J., C. Ryder, M. Mandal, F. Ahmed, P. Azadi, D.S. Snyder, R.D. Pechous, T. Zahrt, and T.J. Inzana. 2007. Attenuation and protective efficacy of an O-antigen-deficient mutant of Francisella tularensis LVS. Microbiol. 153:3141-3153.
Challacombe, J.F., A.J. Duncan, T.S. Brettin, D. Bruce, O. Chertkov, J.C. Detter, C.S. Han, M. Misra, P. Richardson, R. Tapia, N. Thayer, G. Xie, T.J. Inzana. 2007. Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd. J. Bacteriol. 189:1890-1898.
Five most significant publications
Apicella, M.A., D.M.B. Post., A.C. Fowler, B.D. Jones, J.A. Rasmussen, J.R. Hunt, S. Imagawa, B. Choudhury, T.J. Inzana, T.M. Maier, D.W. Frank, T.C. Zahrt, K.Chaloner, M.P. Jennings, M.K. McLendon, B.W. Gibson. 2010. Identification, characterization and immunogenicity of an O-Antigen capsular polysaccharide of Francisella tularensis. PLoS ONE. 5(7): e11060.
Sandal, I. and T.J. Inzana. 2010. Histophilus somni Host-Pathogen Interactions: A Genomic Window into Virulence. Trends Microbiol. 18:90-99.
Inzana, T. J., R. Gogolewski, and L. B. Corbeil. 1992. Phenotypic phase variation in Haemophilus somnus lipooligosaccharide during bovine pneumonia and after in vitro passage. Infect. Immun. 60:2943-2951.
Inzana, T.J., and B. Mathison. 1987. Type-specificity and immunogenicity of the capsular polymer of Haemophilus pleuropneumoniae serotype 5. Infect. Immun. 55:1580-1587.
Inzana, T.J. 1983. Electrophoretic heterogeneity and inter-strain variation in the lipopolysaccharide of Haemophilus influenzae. J. Infec. Dis. 148:492-499.
Synergistic Activities
2008:Chief Organizer: International Pasteurellaceae Conference 2008, Sorrento, Italy, October 12-15
2003-present:Member of International Congress on Systematic Bacteriology: Subcommittee on Pasteurellaceae.
1999-present:Panel member on NIH and USDA grant review sections
2007-present: Member of Editorial Board for Clinical Microbiology Reviews
1991-present:Ad hoc reviewer for many microbiology journals
Collaborators and Co-Editors:
M. Apicella (U of Iowa), P. Azadi (UGA), S. Boyle (VA Tech), T. Brettin (Los Alamos Natl Labs), J. Brisson (Natl Res Council), A. Campagnari (SUNY Buffalo), J. Challacombe (Los Alamos Natl Labs), J. Clarridge (VA Center), L. Corbeil (U San Diego Med School), A. Cox (Natl Res Council), C. Czuprynski (U Wisconsin Madison), B. Fenwick (U Tennessee), G. Berg (VA Tech), M. Lawrence (Mississippi State), A. Lesse (SUNY Buffalo), J. MacInnes (U Guelph), Jennifer McQuiston (CDC), John McQuiston (CDC), M. Perry (Natl Res Council), K. Post (Rollins Anim DIs Diagnostic Lab), J. Richards, (Natl Res Council), I. Sandal (VA Tech), K. Scarratt (VA Tech), G. Schurig (VA Tech), N. Sriragnathan (VA Tech). F. St. Micahel (Natl Res Council), M. Sylte (U Texas), P. Thibault (Natl Res Council), J. Weiser (U Penn), T. Zhart (U Wisconsin Med School)
Graduate and Postdoctoral Advisors:
Porter Anderson (retired), Robert P. Williams (deceased), Shelly Kaplan (Texas Children’s Hospital)
Edward Mason (Texas Children’s Hospital), Jill Claridge (Veteran’s Administration Hospital, Seattle)
Thesis Advisor and Postgraduate-Scholar Sponsor:
Past students:K. Aydintug(unknown), J. Ma: (Boehringer-Ingelheim Vetmedica), C.Ward (Johnson & Johnson Pharmaceutics), T. Lo (Working in industry sales at unknown location), J. Hensle (CDC), J. Schuchert (American Type Culture Collection), M. Howard (retired), S. Elswafii (VCOM), S. Siddaramappa (U of Kansas), Rajiv Balyan (U of Oklahoma)
Current students:A. Champion, Ph.D. candidate, C. Ryder, Ph.D. candidate, A. Hyman: Ph.D. candidate, Y. Pan: Ph.D. candidate, N. Shaw: M.S. candidate, E. Cain: M.S. candidate
POSTDOCTORAL FELLOWS AND VISITING PROFESSORS TRAINED
J. Ma, (Boehringer-Inngelheim Vetmedica), G. Clark, (Eastern Virginia Medical School), T. Letonja, (FDA Center for VeterinaryMedicine), A. Z. Abou(College of Vet. Medicine,Cairo, Egypt), P. Prakash (Visiting Professor from India),T. Pack, (Receptor Pro), M.Lawrence(Mississippi State), Y. Wu(GWU),V. Dobrean (College of Vet. Medicine, Romania), F. Fahmed (currently in San Diego), J. Duncan (Biotech firm in Blacksburg, VA), M. Mandal (Uof Southern Nevada), J. Li, (Institute for Genomic Research), M. Howard(retired), I. Sandal (U of Utah), A.Bandara (VA Tech)