Name ______

DC-Biology

fall 2016

Chapter 12 Cell Cycle Study Questions

1.  What is the cell cycle?

2.  Give three reasons for cell division.

3.  What is the most remarkable part of cell division?

4.  Relate the size of the genome to the size of the cell.

5.  How many chromosomes and pairs of chromosomes do humans possess?

6.  What is chromatin?

7.  What are the roles of the protein associated with the chromosomes in chromatin?

8.  What are chromatids and how many are there in a cell?

9.  What is mitosis and cytokinesis and how are they related?

10.  What is interphase and how much of a typical cell cycle is interphase?

11.  List the three subphases of interphase and tell what happens in each subphase.

12.  List the five subphases of mitosis and tell what happens in each subphase.

13.  Describe the formation of the mitotic spindle making note of the role of the centrosome

14.  Which subphase of mitosis does cytokinesis begin?

15.  What is cleavage and what is the first sign of cleavage?

16.  Compare cleavage in a plant and animal cell.

17.  Discuss the frequency of cell division as it relates to the type of cell and its function in the body.

18.  What is the cell cycle-control system?

19.  What are the three major checkpoints in the cell cycle and which is most important?

20.  What are the two main types of proteins involved in the regulation of the cell cycle ?

21.  What are the two phrases that MPF represents?

22.  How does MPF act both directly and indirectly?

23.  What seems to control all stages of the cell cycle?

24.  What has to happen before anaphase can begin and why is this so important?

25.  Where does the signal that delays anaphase originate?

26.  What is a growth factor and give an example of one.

27.  What is density-dependent inhibition?

28.  What is anchorage dependence?

29.  Give two examples of external signals cancer cells do not heed.

30.  What is the difference between genign and malignant tumors?

31.  List four ways malignant tumor cells are abnormal.