Hofer S, Brenner T et al.Apoptosis versus Necrosis in Severe Septic Patients

Table 2. Comparison of Inflammatory Marker Levels and Cytokeratin Measurements in the Volunteer, Postoperative, and Septic Group at Baseline.

Healthy (n=18) / Post-OP (n=28) / Sepsis (n=101)
IL-6 [pg/ml] / 0.71.4
(range, 0.0-4.5; median, 0.0; interquartile range, 0.0-0.8) / 213.3169.0
(range, 25.5-524.3; median, 216.7; interquartile range, 48.8-360.5) / 304.6375.5
(range, 6.9-2780.8; median, 160.5; interquartile range, 58.8-448.8)
p-values / Healthy vs. Post-OP: p < 0.001***
Healthy vs. Sepsis: p < 0.001***
Post-OP vs. Sepsis: p = 0.604
sICAM-1 [ng/ml] / 250.265.7
(range, 169.8-390.8; median, 219.6; interquartile range, 195.2-285.1) / 317.0251.8
(range, 148.1-1046.9; median, 213.7; interquartile range, 192.3-293.8) / 554.6348.1
(range, 150.7-2293.6; median, 444.7; interquartile range, 330.3-665.5)
p-value / Healthy vs. Post-OP: p = 0.819
Healthy vs. Sepsis: p < 0.001***
Post-OP vs. Sepsis: p < 0.001***
sVCAM-1 [ng/ml] / 1811.21109.3
(range, 702.5-4536.7; median, 1524.7; interquartile range, 991.2-2038.0) / 1460.5544.0
(range, 895.0-2924.4; median, 1268.0; interquartile range, 1167.7-1550.8) / 1743.91674.2
(range, 433.4-13400.0; median, 1147.9; interquartile range, 883.5-2047.4)
p-value / Healthy vs. Post-OP: p = 0.545
Healthy vs. Sepsis: p = 0.280
Post-OP vs. Sepsis: p = 0.450
Full-length CK-18 [U/l] / 270.7100.5
(range, 171.0-509.0; median, 241.9; interquartile range, 216.9-285.3) / 789.3365.4
(range, 367.8-1445.2; median, 558.7; interquartile range, 465.6-793.0) / 3923.76911.8
(range, 271.7-37700.0; median, 1643.8; interquartile range, 1096.5-2633.5)
p-value / Healthy vs. Post-OP: p < 0.001***
Healthy vs. Sepsis: p < 0.001***
Post-OP vs. Sepsis: p < 0.001***
CK-18 fragments [U/l] / 160.150.5
(range, 111.0-278.4; median, 143.7; interquartile range, 134.4-168.1) / 161.569.8
(range, 97.5-297.0; median, 116.0; interquartile range, 106.6-165.1) / 593.4488.0
(range, 125.0-1912.2; median, 392.6; interquartile range, 258.4-654.5)
p-value / Healthy vs. Post-OP: p = 0.250
Healthy vs. Sepsis: p < 0.001***
Post-OP vs. Sepsis: p < 0.001***
Ratio / 0.610.09
(range, 0.50-0.76 median, 0.58; interquartile range, 0.55-0.67) / 0.220.06
(range, 0.13-0.37; median, 0.22; interquartile range, 0.18-0.25) / 0.300.33
(range, 0.04-2.99; median, 0.24; interquartile range, 0.14-0.35)
p-value / Healthy vs. Post-OP: p < 0.001***
Healthy vs. Sepsis: p < 0.001***
Post-OP vs. Sepsis: p = 0.507
Data are presented by mean  standard deviation, range (min-max), median and interquartile range (Q3-Q1).