Research Assistants
Our group is fascinated by how environmental factors such as diet, and lifestyle can alter the way in which our genes are expressed. This is achieved primarily through chemical modifications on DNA, RNA and histone proteins, without any change in the underlying DNA sequence. The study of how these modifications interact with each other to bring about gene regulation is known as epigenetics.
Our research seeks to understand the epigenetic basis of human diseases through the discovery of small molecule probe and inhibitors. Our lab has published several high impact journals in this field of research, such as Angewandte Chemie, Nature Communications and Journal of Medicinal Chemistry.
We are looking for highly motivated Research Assistants to work on the development of anti-obesity drugs.
Requirements:
· Bachelor’s/ Master’s degree in organic/ medicinal chemistry (or equivalent)
· Experience in the synthesis, purification and characterisation of organic compounds
· Experience in enzyme inhibition assay and/or molecular biology techniques is not essential but will be considered favourably
· Be proficient in English, able to work independently, and with good interpersonal and communication skills
Responsibilities include:
· Carry out organic synthesis and inhibition assays
· Assist lab members with current ongoing projects
· Help supervise project students in the lab
· Provide lab support, such as ordering of chemicals and equipments, maintenance of equipments, organising chemical waste disposal and ensuring lab safety
· Administrative work, including filling up of health and safety documents and other relevant and ad-hoc duties
The position is renewable for up to 3 years, depending on the performance of the candidate. Salary and benefits will commensurable with qualifications and working experience. Please address your full application including a cover letter describing your research experiences, a full CV, list of publications (if available) and 2 references to:
Esther Woon, Ph.D.
Assistant Professor
Department of Pharmacy
National University of Singapore
18 Science Drive 4, Singapore 117543
E-mail:
http://www.pharmacy.nus.edu.sg/staff/phaewcy/