Supplementary material
Supplementary figure 1. The CVP N-terminal domain hydrophobic core. The core hydrophobic residues are represented as stick figures and are the color of slate.
Supplementary figure 2. A stereo view of the structure of CVP around active site Cys139. The main chain of the structure is shown in blue.
Supplementary figure 3. The CVP/substrate model. The carbon atoms of substrate and CVP are colored red and blue, respectively.
Supplementary figure 4. (A) A stereo view of tartrate and CVP. The carbon atoms of tartrate and CVP are colored green and yellow, respectively. (B) The 2|Fo|-|Fc| electron density maps of tartrate and CVP.
Supplementary figure 5. CVP/substrate complex structure. The 2|Fo|-|Fc| electron density maps are shown by green mesh. The carbon atoms of CVP are colored green. (detail data not shown)
Supplementary figure 6. Hg coordinated away from the active site of CVP. Hg atoms are represented as grey spheres.