INSTITUTE OF BIOMEDICAL ENGINEERING
Microcomputer Applications in Medicine and Biology
The following topics will be covered in this course: Introduction to medical instrumentation, A/D and D/A conversions, signal processing- hardware versus software, microcomputer design, existing application, a detailed design example--- ambulatory ECG monitoring, and additional applications. The purpose of this course is to acquaint students with the basic principles of biomedical signal processing and microcomputer designs, giving them the capability to develop microcomputer-based biomedical instrumentation.
Biomedical Signal Processing
This course emphasizes signal processing techniques applied to biological signals, such as electrocardiograph (ECG), electromygraphy (EMG), electroencephalograph (EEG) and others. The content of this course includes the origin of bioelectrical signals, random process, time series analysis, and spectral analysis and filter design.
Biostatistics
Basic applications of vectors: statistics of particles, equivalent systems of force, couple and moment, equilibrium of rigid bodies, forces in beams and cables; centroids and centers of gravity and mass, analysis of structures, friction and moments of inertia. Applications of statistics to bio-systems.
Mathematics in Medical Applications
Part I includes differential equations, Laplace transformation, Fourier transformation and their applications in medical engineering. Part II includes linear algebra, vector analysis, complex variables and their applications in medical engineering.
Mechanics of Materials
Introduction of tension, compression, shear and torsion; shear force and bending moment, analysis of stresses and strain, stresses and deflections of beams and columns, and energy methods and elastic stability. Applications of mechanics to bio-systems.
Biomechanics
1. Biomechanics of the locomotor apparatus, contribution to the functional anatomy of the locomotor apparatus; 2. Introduction and application of orthopaedic biomaterials; 3. Human movement.
Biomechanical Experiments
Applying to biomechanical experiments multi-photo gait analysis systems, force plates, joint angle measurements, soft tissue pressure testing systems, muscle force testing machines and monitoring systems, computerized axial and torsional material experiment systems, photoelastic systems and high speed cameras.
Advanced Orthopaedic Biomechanics
From clinical and engineering aspects, we will discuss 1. Advanced mechanical analysis in bones, muscles & tendons; 2.Analysis of bone implant and restoration; 3. Comparison of various types of splints.
Orthopaedic Clinical Engineering
Application of orthopaedic biomechanics to clinical field. Discussion of clinical cases using knowledge of biomechanics and biomaterials to find better operative techniques, and visits to operating rooms to observe orthopaedic operations.
Optimum Design
Basic concepts, functions of one variable, unconstrained functions of n variables, constrained functions of n variables: linear programming, constrained functions of n variable: sequential unconstrained, minimization techniques constrained functions of n variables: direct methods, duality, design applications, applications in muscle mechaniics-analysis of muscle and joint loads.
Finite Element Methods
This course provides a concise introduction to finite element methods (FEM) with an emphasis on engineering aspects (i.e. toward finite element usage rather than finite element theory). The subjects include Overview of FEM, formulation, numerical aspects, modeling techniques and special topics.
Bioelectric Phenomena
This course focuses on bioelectric signal analysis applied to physiology, and will cover the principles and measurements of neural action potential, nerve conduction models, the principles and analysis for the electromyograph, and the conduction model and analysis for electric dipole in the heart.
Biodynamics
This course focuses on the kinematics and dynamics of multibody systems, applied to the study of human movement. The material covered comprises basic concepts, the kinematics of the body reference and the transformation matrices that define the orientation of this body reference, and analytical techniques for deriving the system differential and algebraic equations of motion of a multibody system consisting of rigid bodies. The analytical techniques include LaGrange's equations and Newton-Euler equations. Computer implementation is introduced.
Numerical Analysis
This course introduces the applications of numerical methods from the point view of engineering. The basics of computer programming are a prerequisite. The material covered includes the solution of linear algebraic equations, integration and differentiation of functions, root finding of nonlinear equations, eigensystems, interpolation and extrapolation, integration of ordinary differential equations and two-point boundary value problems.
Medical System Analysis
This course includes the following parts: (1) review of basic mathematical background. (2) Mathematical description of systems. (3) Solutions of dynamic equations. (4) Controllability and observability. (5) Stability analysis. (6) State feedback and state estimator.
Medical Ultrasound
This course includes the following parts: (1) basic wave propagation properties (2) Instrumentation and physics of Diagnostic Ultrasound. (3) Tissue characterization. (4) Other applications, such as hyperthermia and lithotropsy.
Introduction to Bioelectrochemistry
This course gives students a basic knowledge of bioelectrochemistry (1) the basic concepts, (2) the usage of electrochemical instrument and the judgement of voltammogram, (3) the preparation and modification of electrode.
Biomaterial Chemistry
The content of this course includes introduction to natural and artificial polymers, proteins, lipids, saccharides, and their applications.
Computer Aided Design
This course provides a concise introduction to computer aided design (CAD) of engineering applications. The subjects include Introduction to computer engineering, overview of CAD, optimal design, computer graphics, and finite element methods.
Gait Analysis
The course includes studies of the dynamics of human locomotion, of the energy expenditure of normal and disabled persons, and of the effects of immobilization of joints on energy expenditure as well as a clinical evaluation of experimental orthotic devices. It starts with a qualitative description of the displacement in the three planes of space of various components of the skeletal system and provides an overall view of human walking.
Biomechanics of Human Movement
Introductory review of basic principles of mechanics and associated mathematics will be followed by lectures on kinematics and dynamic analyses of human movement. The topics include kinematics of linkage systems and of human movement, comparison of kinematic data acquisition systems, calibration and verification of movement and analysis systems, influence of soft tissue movement, defining the instant helical axes of joints, dynamics of human movement, determination of mass and inertial properties of limb segments, and musculoskeletal models of the human extremities.
Principles of Compound Tomographic Technologies
The content of this course includes introduction to CT technologies, principles of X-ray CT, ultrasonic imaging, MRI and electric current computed tomography, image reconstruction algorithms and 3-D image reconstruction. The origins of noise and artifacts for different modalities of CT will be discussed.
Biosensor
Biosensor is composed of biological device, transducer device and signal display device. we will focus on the selection of biological device and the modification method on its surface. Electrochemical, optical, and piezoelectric methods, as well as design and evaluation will be also discussed.
Advanced Bioelectrochemistry
This course focuses on (1) the theory of electrochemical reaction and digital simulation, (2) electrochemical method under special potential control, (3) the compensative analysis of electrochemistry, (4) electrochemical detection of physiological substances.
Special Topics in Electroanalysis
This course emphasizes electroanalysis based on amperometric, conductive, and potential method. The topics published in new volume of current journal will be introduced and discussed.
Rehabilitation Design and Technology
This course provides practical training in design and fabrication of rehabilitation devices and clinical instrumentation particular to people with physical disabilities. Design concepts, functional disabilities, technological resources, clinical evaluation and manufacturing process are addressed. Students will be assigned to design and fabricate specialized seating systems for neuromuscular disorders, adjustable seating evaluation systems, pressure and deformation devices and simple communication aided devices.
Biostatistics
(1) Intro. & Overview: course outline, reading source, grading policy. (2) Basic Biostatistics: descriptive statistics, basic probability, random variables and distributions, sampling distributions, estimation and inference, and hypotheses testing. (3) Experiment; Design and Analysis of Variance (ANOVA): design & analysis of one-factor, two-factor experiments, one-way and two-way ANOVA, analysis of covariance. (4) Non-Parametric Statistics: rank and sign tests for one sample, two samples and k-sample analysis and their correlations and a wide-range of techniques. (5) Regression Analysis: linear regression analysis and interference, correlation coefficient/ANOVA and their relationships to linear and polynominal regression, multiple regression analysis, correlation, hypotheses testing.
Rehabilitation Engineering
This course will focus on the principles and applications of rehabilitation science & assistive technology from the rehab engineering perspective. As rehab engineering and assistive technology interaction is rarely the expertise of any one profession, a multidisciplinary interaction will be stressed with consideration being given to the roles of various professionals on the team. The course will provide an introductory exposure to at least 8 major areas in the field. Most of the course will be in didactic lecture series, however, laboratory demonstration will also be provided for practical reasons. The major topics will be: wheeled mobility, specialized seating, prosthetics and orthotics, transportation, alternative & augmentative communication, computer access, environmental controls, ADL devices, functional electrical stimulation, and robotics application. Several generic topics will be addressed, such as functional disabilities, information sources, status of the research, and service delivery in the field, standards development and explanation of relevant legislation.
Special Topic of Motion Analysis
Understanding the advanced experimental techniques and fundamental signal processing methods in human movement studies. Current research directions and important studies and applications in medicine, ergonomics, and sports mechanics will be focused on and discussed.
Special Topics of Muscle Mechanics
The purpose of this course is to provide useful information for understanding strength and movement by describing the structure, function, and plasticity of the neuromuscular system. The content includes anatomy and physiology of skeletal muscle, the production of movement, skeletal muscle, the production of movement, skeletal muscle adaptation to increased use and decreased use, and skeletal muscle response to injury.
Spinal Biomechanics
1. Biomechanical aspects of spinal instability. 2. Biomechanical aspects of spinal deformity. 3. The purposes of spinal implants. 4. Kinds of spinal implants. 5. Operative procedures for spinal pathologies. 6. Mechanical studies of spinal implants.
Biomedical Pattern Analysis
The purpose of this course is to introduce pattern analysis techniques and statistical methods applicable to medicine and biology studies. The topics include an overview of pattern recognition, estimation theory, feature extraction techniques, supervised learning, non-supervised learning, principal component analysis and clustering analysis.
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