RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA

BANGALORE

COMPLETED PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION

“A CLINICAL EVALUATION OF THE EFFECT OF UTTARA VASTI IN ASRGDARA W.S.R.TO DYSFUNCTIONAL UTERINE BLEEDING”

BY

Dr. DEEPASHREE

M.S. (Ayu) SCHOLAR

DEPT OF P.G STUDIES IN PRASOOTI TANTRA AND STREEROGA

GUIDE:

Dr. G.RAMADEVI

M.D. (Ayu)

ASST. PROFESSOR.

DEPT OF P.G STUDIES IN PRASOOTI TANTRA AND STREEROGA

CO-GUIDE:

Dr. JONAH.S

M.D. (Ayu)

ASST. PROFESSOR.

DEPT OF P.G.STUDIES IN KAYA CHIKITSA

2008 – 2009

S.D.M. COLLEGE OF AYURVEDA

KUTHPADY, UDUPI – 574118

From,

DR. DEEPASHREE

M.S. (Ayu) SCHOLAR

Dept. of. P.G.studies in Prasooti tantra and streeroga

S.D.M.College of Ayurveda.

Kuthpady, Udupi-574118

To,

THE REGISTRAR,

Rajiv Gandhi University of Health Sciences, Karnataka

Bangalore.

Through,

THE PRINCIPAL,

S.D.M College of Ayurveda.

Kuthpady, Udupi-574118

Respected Sir,

Sub: Submission of completed proforma for registration of synopsis for Dissertation

I request you to kindly register the below mentioned subject against my name for the submission of dissertation to Rajiv Gandhi University of Health Sciences, Bangalore, for partial fulfilment of M.S. (Ayu) in Prasooti tantra and streeroga.

TITLE OF DISSERTATION:

“A CLINICAL EVALUATION OF THE EFFECT OF UTTARA VASTI IN ASRGDARA W.S.R. TO DYSFUNCTIONAL UTERINE BLEEDING”

Here with I am enclosing completed proforma for registration of subject for dissertation.

Thanking You,

Place: Udupi

Yours faithfully,

Date: 30.10.2008

(DR. DEEPASHREE)

1) Name of the candidate : DR. DEEPASHREE

Address : P.G. SCHOLAR

DEPT.OF.P.G. STUDIES IN

PRASOOTI TANTRA AND

STREEROGA

S.D.M. COLLEGE OF AYURVEDA

KUTHPADY, UDUPI-574118

Permanent address : D/O B.RAGHUNATH SHETTY

DEVI KRAPA HOUSE

BALKUNJE -POST

MANGALORE. 574172

DIST-DAKSHINA KANNADA

2) Name of the institution : S.D.M. COLLEGE OF AYURVEDA

KUTHPADY, UDUPI-574118.

3) Course of study and : M.S. (AYURVEDA) IN

subject PRASOOTI TANTRA AND

STREEROGA.

4) Date of admission : 1st JUNE 20008.

of the course

5) Title of the topic :

“A CLINICAL EVALUATION OF THE THE EFFECT OF UTTARA VASTI IN ASRGDARA W.S.R. TO DYSFUNCTIONAL UTERINE BLEEDING”

6. BRIFE RESUME OF THE INTENDED WORK:

6.1 Need for study:

The word “STREE” relates to her capacity of fertilization. The health of a woman to a large extent depends on the normalcy of her menstrual cycle.

In the present era being employed outside in a stressful atmosphere, the episodes of heavy menstrual bleeding are less tolerable, which disturbs her daily routine. The condition ends up with debility and psychological upsets, which hinders the achievement of conception.

As heavy menstrual bleeding (ASRGDARA)1 is a debilitating disorder, the woman requires rapid, safe and effective treatment. Ayurvedic texts have described a variety of treatment options in the management of “ASRGDARA”. Out of them the efficacy of “UTTARA VASTI” 1 is given much more importance by all the acharyas. Uttara vasti though a widely narrated therapeutic option is seldom in practice today. So now it is the need to evaluate the efficacy of this treatment modality scientifically.

6.2 Review of literature:

·  “ASRGDARA” has been explained in

Charaka samhita-chikitsasthana-30th chapter 1

Sushruta samhita-sootrasthana-15th chapter 2

Astanga sangraha-uttarasthana-38th ,A.hrdaya-uttarasthana-33rd chapter 3

·  “UTTRA VASTI” has been explained in

Charaka samhita-siddisthana-9th chapter 1

Sushruta samhita-chikitsasthana-37, 38th chapter 2

Astanga sangraha-sootrasthana-28th, A.Hrdaya-sootrasthana-19th chapter 3

Previous works done:

·  Jain Suman (1991); Banaras Hindu University-Varanasi, has done work on “Role of Yoga basti in Asrgdara”. 6

·  Annathayya Sulochana (1992); Gujarat Ayurveda University –Jamnagar, has done a study of Asrgdara w.s.r. to DUB”. 6

·  Kumari Ambili T(1996); Govt. Ayurveda college – Trivendrum, has done a study on the effect of Pushyanuga choorna in Asrgdarra.” 6

·  Vinuta C (2003); SDMCA – Udupi, RGUHS Bangalore, has done work on a

clinical evaluation of the effect of certain indegenous drugs and Uttara vasti in Pradara w.s.r.to DUB”.

6.3) Objectives of the study:

·  To make a comprehensive literary review of “ASRGDARA” and “DUB”.

·  To evaluate the efficacy of “PUSHYANUGA CHOORNA” in Asrgdara.

·  To evaluate the efficacy of “UTTARA VASTI” in Asrgdara.

·  To evaluate the efficacy of “UTTARA VASTI ” after “YOGA VASTI ” in Asrgdara

·  To compare the above 3 GROUPS.

7) MATERIALS AND METHODS:

7.1) Source of data:

Minimum 30 patients suffering from Asrgdara will be selected for the study from the OPD and IPD of S.D.M Ayurveda Hospital Kuthpady, Udupi.

7.2) Method of data collection:

·  Patient presenting with complaints of excessive menstrual bleeding and irregular bleeding as that of menorrhagia, metrorrhagia and polymenorrhoea will be selected.5

·  A detailed proforma will be prepared considering all the patients pertaining to history, signs, symptoms and examination as mentioned in our classics and allied sciences to confirm the diagnosis.

Inclusion criteria:

·  Patient with age group of 20 to 45 years.

·  Patient with pratyatma lakshana of Asrgdara.

·  Patient diagnosed as DUB.5

Exclusion criteria:

·  Patient with thyroid dysfunction, DM, HTN etc.

·  Threatened or spontaneous or incomplete abortion.

·  Bleeding disorders like thrombocytopenia etc.

·  STD, Patient with IUCD, polyp, benign and malignant tumours of uterus.

INTERVENTION:

Patients fulfilling above criteria are selected and assigned in to 3 GROUPS :

GROUP 1 – of 10 patients will be administered “PUSHYANUGA CHOORNA” 4 about 12g with MADHU in three divided doses, with 100ml of TANDULODAKA in empty stomach for a period of one month.

GROUP 2 – of 10 patients will be administered “KASHMARYA KUTAJA GRITA UTTARA VASTI ” 1 for 3 days.

GROUP 3 – of 10 patients will be administered “KASHMARYA KUTAJA UTTARA VASTI ” 1 for 3 days, after a course of “YOGA VASTI ” for 5 days with “BALA TAILA ANUVASANA” and “DASHAMOOLA KASHAYA NIRUHA VASTI ”.

FOLLOW UP —Patient will be asked to follow-up for the next 2 cycles.

ASSESSMENT CRITERIA:

1.

·  Duration of flow – if bleeding lasts for more than 5 days.

·  Interval between 2 menstrual cycles – if more than 21 days.

·  Amount of menstrual blood loss – use of no. of pads per day.

·  Clots – present or absent.

·  Staining – present or absent.

·  Odour – present or absent.

·  Pain – Mild (+)

Moderate (++)

Severe (+++)

2. Uterine size: - P/V examination or USG if needed

3. FINAL ASSESSMENT:

Cured

§  Regularization of menstruation, i.e. 3-5 days / 28-30 days.

§  Regularization in amount of bleeding, using 1-2 pads per day.

§  Reduction in associated symptoms like pain.

Improved - Mild improvement in amount of bleeding, length of the cycle & pain.

No relief – No change.

7.3) Does the study require any investigation or intervention to be conducted on patients or other humans or animals? If so, please describe briefly.

Yes, The study will be conducted on human subjects who match the inclusion criteria only.

Investigations:

Hb%, CT, BT, USG, Hormonal essay, Endometrial biopsy (if necessary).

7.4) Has ethical clearance been obtained from your institution in case of

7.3?

Yes, Concurrence has been obtained from the ethical committee of S.D.M. Ayurveda Hospital.

8) List of References;

1.  Agnivesha; Charaka Samhita, Commentary ‘Ayurveda deepika’ of Chakrapanidatta; edited by Yadavji trikamji acharya; Published by Varanasi, Chaukhamba Surabharati Prakashana; reprinted in 2008, Pp-738, p-639,720.

2.  Sushruta; Sushruta Samhita, commentary Dalhanacharya virachita ‘Nibandha Sangraha vyakhya’ and Nyayachandrika panjika of Gayadasacharya on nidanasthana; edited by Yadavji Trikamji acharya, Published by Varanasi, Chaukhamba Surabharati Prakashana; reprinted in 2008, Pp-824, p- 70,537,538.

3.  Vagbhatacharya; Astanga Hridayam with commentaries ‘Sarvangasundara’ of Arunadatta and ‘Ayurveda rasayana’ of Hemadri; edited by pandit Bhishagacharya Hari shastri paradkar; Published by Varanasi, Chaukhamba Surabharati Prakashana; reprinted in 2007, Pp- 953, p- 283, 896.

4.  Kaviraj Ambikhadatta shastri Ayurvedacharya; Bhaishajjya Ratnavali; Vidyotini hindi vyakya, 2nd edition, published by Varanasi, Chaukamba Sanskrit samsthana, Pp-891, p-717,718.

5.  Datta D.C. Text book of Gynaecology including contraception, edited by Hiralal Konar, 5th edition:2008, Pp-627, p- 183.

6.  .Bhagel M.S. ; Researches in Ayurveda; published by Chaukamba publications; in 2005, Pp-381, p- 86, 52, 161.

7.  Vinuta C- “A clinical evaluation of the effect of certain indigenous drugs and Uttara basti in Pradara”, SDMCA Udupi, RGUHS Bangalore (unpublished doctoral dissertation 2003

9) Signature of the candidate:

10) Remark of the Guide:

11) Name and designation:

11.1) Guide: Dr. G.RAMADEVI M.D.(Ayu)

ASST. PROFESSOR.

DEPT OF P. G. STUDIES IN

PRASOOTI TANTRA STREEROGA

S. D. M. COLLEGE OF AYURVEDA.

KUTHPADY, UDUPI-574118

11.2) Signature:

11.3) Co-Guide: DR. JONAH.S M.D. (Ayu)

ASST. PROFESSOR.

DEPT OF P. G. STUDIES IN

KAYA CHIKITSA

S.D.M.COLLEGE OF AYURVEDA

KUTHPADY, UDUPI – 574118

11.4) Signature:

11.5) Head of the Department: DR. V. N. K. USHA M. D. (Ayu)

PROFESSOR.

DEPT OF P. G. STUDIES IN

PRASOOTI TANTRA & STREEROGA

S. D. M. COLLEGE OF AYURVEDA.

KUTHPADY, UDUPI-574118

11.6) Signature:

12)

12.1) Remarks of the chairman

& the Principal:

12.2) Signature: