Dialysis Diffusion Lab

Purpose/Objective:

To simulate the process of diffusion

To determine which substance(s) can diffuse through a semi-permeable membrane (dialysis tubing)

Materials:

Sugar Solution Starch Solution Glass Rod

Dialysis Tubing Pipettes (2) Test Tubes (4)

Test Tube Rack Iodine Solution String

Benedicts Solution 250 ml Beaker Hot Water Bath

Procedure:

1) Prepare the dialysis tubing as follows:

- rub ends of the tubing apart between your fingers; use a glass rod to help assist you

- twist one end of the tubing, fold it over, and tightly tie off with a piece of string

2) Fill the dialysis tubing ½ full with starch solution and ½ full with sugar solution

3) Twist the other end of the tubing, fold it over, and tightly tie off with a piece of string.

4) Rinse the dialysis bag carefully under the sink with water and then submerge in a beaker of water for 20 minutes.

5) Label your four test tubes: #1, #2, #3, #4 (make sure to use a distinguishing mark to identify yours)

6) After 20 minutes, take a pipette full of water from the beaker and add it to test tube #1.

7) To test for the presence of sugar, add 10 drops of Benedicts Solution to test tube #1 and heat it for 10 minutes in a hot water bath. Record your observations in the Data/Results Table.

8) Put another pipette full of water from the beaker into test tube #2.

9) To test for the presence of starch, add 3 drops of Iodine solution to test tube #2. Record your observations in the Data/Results Table.

10) Open the dialysis bag and put one pipette full of solution from the dialysis bag into test tube #3.

11) Add 10 drops of Benedicts Solution to test tube #3 and heat it for 10 minutes in a hot water bath. Record your observations in the Data/Results Table.

12) Put another pipette full of solution from the dialysis bag into test tube #4.

13) Add 3 drops of Iodine solution to test tube #4. Record your observations in the Data/Results Table.

14) Clean up…rinsing all materials thoroughly.

Data/Results:

Test Tube # / Substance Tested for / Location of Solution / Description of Color / Presence of Substance (+ / - )

* Substance Tested for: Starch or Sugar

* Location of Solution: Beaker or Dialysis Bag

* Presence of Substance: + = positive test - = negative test

Discussion:

1) Which two substances are being tested for in this experiment?

2) Why do you rinse the dialysis bag with water before placing it into a beaker of water to soak?

3) What color did test tube #1 turn after heating? How does this compare to test tube #3? What does

this mean?

4) What color did test tube #2 turn after adding Iodine Solution? How does this compare to test tube

#4? What does this mean?

5) To which substance(s) is the dialysis tubing permeable?

6) Explain how the dialysis tubing acted like a semi-permeable membrane.

7) Explain how diffusion was demonstrated in this experiment.