The main reason for the submission of these data is that they are the 3 cohorts used in the following paper:
Power, J.D., K.A. Barnes, A.Z. Snyder, B.L. Schlaggar, S.E. Petersen (2011). Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage Epub ahead of print, doi:S1053-8119(11)01181-5 [pii] 10.1016/j.neuroimage.2011.10.018
All of these subjects are controls with no diagnosis.Full scale IQ scores are from the 2 subtest WASI.
Many of the subjects were also used for analyses in the following journal articles:
Power, J.D., et al. (2011). Functional network organization in the human brain. Neuron 72, 665-678
Vogel, A.C., Power, J.D., Petersen, S.E., Schlaggar, B.L. (2010). Development of the brain’s functional network architecture.Neuropsychol Review.20:362–375.
Dosenbach, N.U.F., Nardos, B.,Cohen, A. L.,Fair, D. A.,Power, J. D., Church J.A.,Nelson, S. M., Wig G.S., Vogel, A.C., Lessov-Schlaggar, C.N., Barnes, K.A., Dubis, J.W., Feczko, E.,Coalson, R. S., Pruett Jr.,J.R.,Barch, D. M.,Petersen, S. E.,Schlaggar, B. L. (2010). Prediction of individual brain maturity using fMRI.Science 329, 1358-1361.doi:329/5997/1358 [pii] 10.1126/science.1194144
Power, J.D., Fair, D.A., Schlaggar, B.L., Petersen, S.E. (2010).The development of human functional brain networks.Neuron 67:735-748.
Barnes, K. A., Cohen, A. L., Power, J. D., Nelson, S. M., Dosenbach, Y. B. L., Miezin, F. M., Petersen, S. E., and Schlaggar, B. L. (2010). Identifying Basal Ganglia divisions in individuals using resting-state functional connectivity MRI. Front SystNeurosci 4, 18.
Barnes, K.A., et al. (2011). Parcellation in left lateral parietal cortex is similar in adults and children. Cereb Cortex CerCor-2011-00246.R1,
Nelson, S.M., Cohen, A., Power, J., Wig, G., Miezin, F.M., Wheeler, M.E., Donaldson, D.I., Velanova, K., Phillips, J., Schlaggar, B.L., Petersen, S.E. (2010) A Parcellation Scheme for Human Left Lateral Parietal Cortex.Neuron, 67(1):156-170.
Nelson, S.M., Dosenbach, N.U., Cohen, A.L., Wheeler, M.E., Schlaggar, B.L., Petersen, S.E. (2010) Role of the anterior insula in task-level control and focal attention.Brain Structure and Function, 214:669-680.
Study 0: Functional Connectivity Regions(repeat from initial submission)
Names and Titles of PI and all senior personnel members
Steve Petersen, Ph. D.
James S. McDonnell Professor of CognitiveNeuroscience
Director, McDonnell Center for SystemsNeuroscience
Depts. of Neurology and Psychology
Washington University Medical School
Bradley L Schlaggar MD PhD
A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology
Associate Professor of Radiology, Pediatrics, and Anatomy & Neurobiology
Director, Pediatric Neurology Residency Training Program
Director, Pediatric Movement Disorder Program
Washington University School of Medicine & St. Louis Children's Hospital
Alexander L. CohenGraduate Student
Funding Sources/Grants
NSF/IGERT Program Fellowship (Cognitive, Computational, and Systems Neuroscience Pathway) to Alexander L. Cohen
Washington University Chancellor’s Fellowship and UNC/Merk Graduate Science Research Dissertation Fellowship to Damien Fair
NIH NSADA (Brad Schlaggar)
NS32979 (Steve Petersen)
NS41255 (Steve Petersen)
NS46424 (Steve Petersen)
The McDonnell Center for Higher Brain Function (Steve Petersen and Brad Schlaggar)
The Burroughs Wellcome Fund (Brad Schlaggar)
The Charles A. Dana Foundation (Brad Schlaggar)
Acknowledgements
Damien A. Fair, Nico U. F. Dosenbach, Francis M. Miezin, Donna Dierker, David C. Van Essen, Jessica A. Church, Steven M. Nelson, John Harwell
List of Publications that include the data being released
Cohen AL, Fair DA, Dosenbach NU, Miezin FM, Dierker D, Van Essen DC, Schlaggar BL, Petersen SE (2008) Defining functional areas in individual human brains using resting functional connectivity MRI. Neuroimage 41:45-57
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- Flickering checkerboard quadrants with button press
- Follow the target saccades
- Abstract/Concrete judgement on visual words
Study 1: Augmentative Communication
Names and Titles of PI and all senior personnel members
Steve Petersen, Ph. D.
James S. McDonnell Professor of CognitiveNeuroscience
Director, McDonnell Center for SystemsNeuroscience
Depts. of Neurology and Psychology
Washington University Medical School
Bradley L Schlaggar MD PhD
A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology
Associate Professor of Radiology, Pediatrics, and Anatomy & Neurobiology
Director, Pediatric Neurology Residency Training Program
Director, Pediatric Movement Disorder Program
Washington University School of Medicine & St. Louis Children's Hospital
Rebecca S. Coalson B.S.Research Patient Coordinator
Funding Sources/Grants
The Brooks Family Fund
Acknowledgements
Kelly R. McVey, Rebecca L. Lepore, Fran M. Miezin, Mary Downey-Jones, Jane K. Quarles, Tara V. Spevack, Melanie Wood, Janice Lanto, Alex L. Cohen
List of Publications that include the data being released
None specifically on this study
Resting State Info
- Eyes open, 3 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- 5 minute runs watching the movie Finding Nemo or an aquarium video clip
Study 2: Development of Orthography
Names and Titles of PI and all senior personnel members
Steve Petersen, Ph. D.James S. McDonnell Professor of CognitiveNeuroscience
Director, McDonnell Center for SystemsNeuroscience
Depts. of Neurology and Psychology
Washington University Medical School
Bradley L Schlaggar MD PhDA. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology
Associate Professor of Radiology, Pediatrics, and Anatomy & Neurobiology
Director, Pediatric Neurology Residency Training Program
Director, Pediatric Movement Disorder Program
Washington University School of Medicine & St. Louis Children's Hospital
Alecia C. Vogel, PhDPostdoctoral Fellow
Funding Sources/Grants
R01-Schlaggar-R01HD057076
RO1 NS046424
Acknowledgements
Rebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Gordon Shulman
List of Publications that include the data being released
Vogel AC, Miezin FM, Petersen SE, Schlaggar BL (2011) The putative visual word form area is functionally connected to the dorsal attention network. Cereb Cortex Jun 20. [Epub ahead of print].
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- collected 5 minute resting runs at the end of a 2+ hour session ofVISUAL MATCHING AND READINGtasks
Study 3: Jess Task Switching
Names and Titles of PI and all senior personnel members
Bradley L Schlaggar MD PhDA. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology
Associate Professor of Radiology, Pediatrics, and Anatomy & Neurobiology
Director, Pediatric Neurology Residency Training Program
Director, Pediatric Movement Disorder Program
Washington University School of Medicine & St. Louis Children's Hospital
Jessica A. Church, PhDPostdoctoral Fellow
Funding Sources/Grants
NIH NINDSNRSA-F32 NS656492 Church
NIH NIMHR21-Schlaggar
R01-Schlaggar-R01HD057076
Tourette Syndrome Association-Schlaggar
Tourette Syndrome Association-Church
Acknowledgements
Rebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen, Silvia Bunge (UC Berkeley),YannicDosenbach, Sarah Katie Zeller Ihnen, Kelly Anne Barnes
List of Publications that include the data being released
Church JA, Fair DA, Dosenbach NU, Cohen AL, Miezin FM, Petersen SE, Schlaggar BL (2009) Control networks in paediatric Tourette syndrome show immature and anomalous patterns of functional connectivity. Brain 132:225-238.
Church JA, Wenger KK, Dosenbach NU, Miezin FM, Petersen SE, Schlaggar BL (2009) Task control signals in pediatric Tourette syndrome show evidence of immature and anomalous functional activity. Frontiers in Human Neuroscience 3:38.
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- collected 5 minute rest runs interspersed with a task-switching paradigm, eg.
- if the cue is color, press left button for pink or right for green
- if the cue is cartoon, press left for fish or right for squid
Study 4: Unilateral Hearing Loss
Names and Titles of PI and all senior personnel members
Judith E. C. Lieu, MD, Assistant Professor of Otolaryngology
Bradley L Schlaggar MD PhD
A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology
Associate Professor of Radiology, Pediatrics, and Anatomy & Neurobiology
Director, Pediatric Neurology Residency Training Program
Director, Pediatric Movement Disorder Program
Washington University School of Medicine & St. Louis Children's Hospital
Jill B. Firszt, PhD, Associate Professor of Otolaryngology
BananEad, Research Patient Coordinator
Funding Sources/Grants
American Hearing Research Foundation
NIH grant K23DC006638
Acknowledgements
Kathleen Tibbits, Amy Streufert, Rebecca S. Coalson, Fran Miezen
List of Publications that include the data being released
Tibbetts K, Umansky AM, Ead B, Coalson RS, Schlaggar BL, Firszt JB, Lieu JEC. Inter-regional brain interactions in children with unilateral hearing loss.Otolaryngology-Head and Neck Surgery 144 (4):602-611, 2011. doi:10.1177/0194599810394954
Resting State Info
- Eyes open, 3 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- DTI was also collected
Study 5: Deanna Barch
Names and Titles of PI and all senior personnel members
Deanna Barch, Gregory B Couch Professor of Psychiatry
Director, Conte Center for the Neuroscienceof Mental Illness
Washington University
Lizzie Gilman Professor and Chair, Department of Psychiatry and Behavioral Sciences
Washington University
GregaRepovs, Associate Professor, Psychology Department
Washington University
Funding Sources/Grants
NIMH grant P50 MH071616
Acknowledgements
List of Publications that include the data being released
Repovs, G., Csernansky, J. G., & Barch, D. M. (2011). Brain network connectivity in individuals with schizophrenia and their siblings.Biological Psychiatry, 69, 967-973.
Repovs, G. and Barch, D. M. (submitted). Working memory related brain network connectivity in individuals with schizophrenia and their sibilngs.
Resting State Info
- Eyes open, 5.5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- Mixed State Item Nback with loads of 0, 1 and 2 back
Study 6: Autism Controls
Names and Titles of PI and all senior personnel members
Steve Petersen, Ph. D.
James S. McDonnell Professor of CognitiveNeuroscience
Director, McDonnell Center for SystemsNeuroscience
Depts. of Neurology and Psychology
Washington University Medical School
John R. Pruett, Jr., M.D., Ph.D.
Assistant Professor
Department of Psychiatry, Division of Child & Adolescent Psychiatry
Washington University School of Medicine
Eric FeczkoGraduate Student
Funding Sources/Grants
Simons Foundation Autism Research Initiative – Steve Petersen
Acknowledgements
Sarah Hoertel, Kelly McVey, Fran Miezen, Emma Squire, Anna Abacchi, Angie LaMacchia Moll
List of Publications that include the data being released
None specifically on this data yet
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- “Do you see the plus sign?”
- “For the next scan, keep your eyes open, try not to move your head, arms, legs, hands, feet, fingers, or toes, but you can blink and breathe like you normally would. Try your best to look at the plus sign and this scan will take about five and a half minutes. Let me know as soon as you’re ready to start”
Other Tasks in this Study
- Fixate on plus sign, periodically a flickering checkerboard will appear
- Press one button when it appears; Press another button when it disappears
- Eyes closed rest
- DTI was collected
Study 7: Tammy Hershey
Names and Titles of PI and all senior personnel members
Tamara Hershey, Ph.D.
Associate Professor
Psychiatry, Neurology and Radiology Departments
Washington University School of Medicine
Funding Sources/Grants
Diabetes Research and Training Center at Washington University and the National Institute of Diabetes and Digestive and Kidney Diseases (5 P60 DK020579-31)
Acknowledgements
Heather Lugar, Brenda Kirchhoff
List of Publications that include the data being released
None specifically on this study
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- an associative encoding task
Study 8: Scanner Comparison
Names and Titles of PI and all senior personnel members
Carolyn Pizoli, MD/PhD
Assistant Professor
Division of Pediatric Neurology
Duke University Medical Center
Christine Mac Donald, PhD
Research Instructor, Department of Neurology
Director - Advanced MRI and Blast-RelatedTBI Study
Washington University School of Medicine
David Brody, MD, PhD
Assistant Professor in the Department of Neurology
Washington University site director for the National Football League player care program
Funding Sources/Grants
K 12 NS-001690is the NSADA K12
Acknowledgements
Tammy Benzinger
List of Publications that include the data being released
None specifically on this data
Resting State Info
- Eyes open, 5 minute runs
- No other instructions, no fixation cross
Other Tasks in this Study
- DTI also acquired
Study 9: Twin Study
Names and Titles of PI and all senior personnel members
Christina N. Lessov-Schlaggar, PhD
Research Assistant Professor of Psychiatry
Washington University School of Medicine
Department of Psychiatry
Funding Sources/Grants
The study was supported by the Barnes-Jewish Hospital Foundation in Saint Louis, Missouri, and by grants from the McDonnell Center for Systems Neuroscience at Washington University (CNLS), the Alvin J. Siteman Cancer Center (supported in part by an NCI Cancer Center Support Grant #P30 CA91842) at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, Missouri, for use of the Prevention and Control Research Program (CNLS), and NIH grant DA027046 (CNLS). Diagnostic interview surveys of the total twin cohort were supported by NIH grant AA009022 (ACH).
Acknowledgements
Rebecca Lepore, Rebecca S. Coalson, Kelly McVey, Fran Miezen
List of Publications that include the data being released
Lessov-Schlaggar CN, Lepore RL, Kristjansson SD, Schlaggar BL, Barnes KA, Petersen SE, Madden PAF, Heath AC, Barch DM. Functional neuroimaging study in identical twin pairs discordant for regular cigarette smoking. Addiction Biology (accepted)
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- Monetary reward task – guess whether hidden number is larger or smaller than 5. If correct, win $1; if wrong, lose 50 cents.
- Smoking status of individuals was assessed, as well as blood CO levels.
- Identical twins were recruited for this study.
Study 10: Joe’s First Visual Attention
Names and Titles of PI and all senior personnel members
Steve Petersen, Ph. D.
James S. McDonnell Professor of CognitiveNeuroscience
Director, McDonnell Center for SystemsNeuroscience
Depts. of Neurology and Psychology
Washington University Medical School
Bradley L Schlaggar MD PhD
A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology, in Neurology
Associate Professor of Radiology, Pediatrics, and Anatomy & Neurobiology
Director, Pediatric Neurology Residency Training Program
Director, Pediatric Movement Disorder Program
Washington University School of Medicine & St. Louis Children's Hospital
Joseph W DubisGraduate Student
Funding Sources/Grants
McDonnell Foundation Grant
R21
Acknowledgements
Rebecca S Coalson, Kelly McVey, Rebecca Lepore, Joshua Siegel, Mary Downey-Jones, Fran Miezen
List of Publications that include the data being released
None specifically on this data yet
Resting State Info
- Eyes open, 5 minute runs
- White fixation cross on black background
- "loosely fixate on the white cross"
Other Tasks in this Study
- After a spatial left or right cue arrow, shapes appeared. Subjects pressed a button when they detected that one of the shapes changed orientation angle.