PHARMACEUTICAL PRESS – TEXTBOOK

ISBN:978 0 85369 843 2 Paperback Pub date:Jan 2011
Extent:160 pagesFormat:234 x 156mm Price:£29.99

Biological Therapeutics

EDITION:First

AUTHORS:Ben Greenstein,Senior Visiting Research Fellow,Pain Management team, Royal Free Hospital, London, UK

Daniel A Brook, General Practitioner,London, UK

______

PRODUCT SUMMARY:

This textbookoffers an introduction to the most exciting and fastest-growingbranch of pharmaceutical science at the present time: the treatment of disease using biological medicines derived from living plant and animal tissues. All categories of biological therapeutics are covered in this comprehensive overview. Chapter features include historical introductions, an overview of the drugs and their mechanisms of action, uses, examples of adverse reactions and case studies.

______

UNIQUE BENEFITS:

-Relatively new subject area so there are very few texts on this topic

-Addresses the use of vaccines for humans and also animals

-There is currently an increased use and interest in new therapies based on biological molecules so practitioners need to keep up to date with the latest developments

-This is an area that is being introduced to the pharmacy undergraduate curriculum so will be of interest to final year students.

______

READERSHIP:

Primary: Medical and pharmacy students, postgraduate students studying pharmacy, molecular biology and related disciplines.

Secondary:Practitioners prescribing biologics

______

PEDAGOGICAL FEATURES:

Includes case studies

______

INTERNATIONAL SCOPE:

UK, Europe, ROW, North America - This title shouldtravel well

______

FORMAT AVAILABILITY:

Book

eBook platforms: EBL/EBooks.com, MyiLibrary, NetLibrary andR2 Library

______

ASSOCIATED TITLES:

All Pharmaceutical Press science and industrytexts

KEY COMPETITION:

There is no direct competition as this is a new area in the pharmacy undergraduate curriculum

Title / Author(s) / Publisher / Date / Price / Length / Target Audience / Additional Info / Comments
Biologics in General Medicine / Boehnicke WH (ed) / Springer / 2007 / £99.99 / 190 pp / Post-grads / Hardback
- German Editor / - Very Expensive
- For graduate college "Biologicals" at Goethe University Frankfurt
- 3 Years old

______

CONTENTS:

PHARMACEUTICAL PRESS – TEXTBOOK

ISBN:978 0 85369 843 2 Paperback Pub date:Jan 2011
Extent:160 pagesFormat:234 x 156mm Price:£29.99

1 Introduction to genetic manipulation

Nucleotides and the genetic code

Recombinant DNA technology

The tools used for recombinant DNA technology

Mass production of insulin: an example

Knockout mice

Multiple choice questions

Further reading

2 Vaccines

Definition of a vaccine

A brief history

Miniglossary

Immunity

Mechanism of action of vaccines

Production of vaccines

Modern production methods

Paradigm of a coordinated response to the threat of an influenza pandemic

Some examples of specific vaccines

Multiple choice questions

References

Further reading

3 Hormone-related drugs

Brief history

Thyroid hormones

Adrenal hormones

The sex hormones

Biological drugs and cancer chemotherapy

Calcitonin

Parathyroid hormone

Insulin

Growth hormone

The incretins

Multiple choice questions

Further reading

4 The nature of inflammation and mediators of inflammation

Hypersensitivity

Mechanisms and chemical mediators of the inflammatory response

The interferons

Multiple choice questions

Further reading

5 Autoimmunity and autoimmune diseases

Autoimmunity

Immunological tolerance

Low-level autoimmunity

Triggers and mechanisms of autoimmune reactions

Some cellular mechanisms implicated in loss of self-tolerance and onset and maintenance of autoimmune states

Multiple choice questions

Further reading

6Treatment of rheumatoid arthritis and other inflammatory disorders with biological drugs

Rheumatoid arthritis

Administration of biological drugs

Psoriasis

Systemic lupus erythematosus

Crohn’s disease

Multiple choice questions

Reference

Further reading

7 Development of biological antineoplastic drugs

Mechanisms and targets for biological antineoplastic drugs

Some biological antineoplastic drugs currently in use or development

Effectiveness of the biological treatments for cancer

Multiple choice questions

Further reading

8 Stem cell therapy

The nature of stem cells

Embryonic stem cell cultures

Preparation of stem cells from the blastocyst

Prospects and the future for regenerative medicine

References

Further reading

Multiple choice answers

Glossary

Index