3MTMTECRA SalmonellaVisual Immunoassay (VIA) - AOAC 998.09
SCOPE
These methods are applicable to:
Raw meats, carcass swabs and food in general;
Methods differ in the selective liquid enrichment broths and incubation time/temperatures used.
PRINCIPLES
The detection of Salmonella spp. is broken down into stages as follows:
Pre-enrichment
A 1:10 dilution of the sample must be pre-enriched in buffered peptone water at 37 ± 1C for 18 ± 2 h. Buffered peptone water should be warmed to room temperature or to 37C for large volumes. For carcass sponges, buffered peptone water is added to the moistened sponge to bring the total volume to 60-100 ml and the sample incubated at 37 ± 1C for 18 ± 2 h. In the case of sponges BPW need not be warmed to room temperature before being used to re-hydrate the sponge, for all subsequent additions BPW should be warmed to room temperature.
Selective enrichment
Culture from the pre-enrichment broth is inoculated into Rappaport-Vassiliadis R10 broth and tetrathionate (TT) broth incubated at 41-43 C for 16-20 h. Store all broths at 2-8C for possible cultural confirmation using AS 5013.10.
Post-enrichment
Inoculate cultures obtained from the selective enrichment into M broth and incubate at 35-37C for 6 h. Store all broths at 2-8C for possible cultural confirmation using AS 5013.10.
Enzyme immunoassay
Follow the manufacturer’s instructions.
Cultural confirmation
Using retained selective enrichment broths and M-broths, proceed with Salmonella analysis as per AS 5014.10-2004 (starting from ‘Plating out and Identification’). Confirmation carried out at an ‘off-site’ laboratory must be from retained BPW enrichment or M-broths.
Issue 2017 01 10
Export Standards Branch | Exports Division Page 1 of 2
Department of Agriculture and Water Resources
3MTM TECRASalmonellaVIA –AOAC 998.09
CHECKLIST
Pre-enrichment / Is the buffered peptone water warmed to room temperature (to 37C for large quantities)?Is the correct amount of enrichment broth used for the weight of sample analysed?
Is pre-enrichment done at 37 ± 1C for 18 ± 2 h?
Is a positive control run with each batch of samples analysed?
Are reference cultures inoculated into primary enrichment broth at a level of 10 to 100 cells?
Selective-enrichment / Are selective enrichment broths incubated at the appropriate temperature?
Are selective broths within their use-by-date?
Post-enrichment / Is M broth incubated at 35-37C for 6 h?
Are all selective enrichments stored correctly for possible cultural confirmation?
Immunoassay / Are the manufacturer’s instructions available?
Cultural confirmation / Is Salmonella isolated in-house from enrichment broths?
(if applicable) / If an external laboratory is used is it department approved?
BPW should be supplied to off-site laboratories for confirmation following AS 5013.10
Are Salmonella confirmed using AS 5013.10 (with appropriate selective agar plates)?
Issue 2017 01 10
Export Standards Branch | Exports Division Page 1 of 2
Department of Agriculture and Water Resources