1. Identity
Title: Prof, MD, PhD
Family Name: Brzosko
First Name: Marek
Birth Date: 19/12/1954
Institute/Organisation: University Hospital of Szczecin
Department: Rheumatology and Internal Medicine
Address: Unii Lubelskiej 1
Post Code: 71-252
City: Szczecin
Country : Poland
E-mail:
2. General Curriculum Vitae
Education:
1979: doctor, Pomeranian Medical University in Szczecin
1983: Specialist in internal diseases (1st degree, with distinction)
1986: Specialist in internal diseases (2nd degree, with distinction)
1991: PhD Thesis on low back pain (summa cum Laude)
2003: Specialist in rheumatology (2nd degree)
2007: Associated Professor, Pomeranian Medical University in Szczecin
2010 : Professor of Rheumatology, Pomeranian Medical University in Szczecin
Qualifications:
1992: Second Applied Epidemiology Course for Rheumatologists, Manchester, Great Britain
1994: 11th International Epidemiology Summer School, Bochum, Germany
1995: The Advanced International Course on Principles of Epidemiologic Research, Lunteren, The Netherlands,
1996: ARC Epidemiology internship, Manchester, Great Britain
Employment:
From 1982 : Senior Assistant Hematology and Internal Diseases Dept. of University Hospital in Szczecin
From 1992: Head of the ward in Rheumatology and Internal Diseases Dept. of University Hospital in Szczecin
Research interests:
Rheumatic diseases, immunology
Scientific Association Membership:
Chairman of the Polish Society of Rheumatology in Szczecin
Vice-chairman of the Polish Society of Rheumatology
Scientific Activity:
Multiple peer reviewed papers in Polish and international journals
Multiple book chapters
Author of books: Reumatologia kliniczna, Ed: Marek Brzosko, Wydawnictwo Pomorskiego Uniwersytetu Medycznego, Szczecin, 2007 and 2010; Reumatologia praktyczna, Ed: Włodzimierz Samborski, Marek Brzosko, ABC Wolters Kluwer, Warszawa 2011
Reviewer for peer-reviewed journals
Multiple invited presentations at national/international scientific meetings
Supervisor of doctors thesis of 7 doctors: Jacek Flicinski, Krzysztof Prajs, Katarzyna Fischer, Agnieszka Dąbrowska-Zimoń, Małgorzata Łukjanowicz, Beata Trzcińska Butkiewicz, Marcin Milchert
3. Important publications
1. Flicinski J, Brzosko M, Olewniczak S: Multiple haemangiomas in a psoriatic arthritis patient treated with cyclosporine. Acta Derm Venereol. 2006; 86:271-2 (IF=1.837)
2. Jaworowska E, Masojć B, Tarnowska C, Brzosko M, Fliciński J, Serrano-Fernandez P, Matyjasik J, Amernik K, Scott RJ, Lubiński J: Association between early-onset breast and laryngeal cancers. Breast Cancer Res Treat. 2006; 97: 215-9 (IF=4.671)
3. Milchert M, Fliciński J, Ostanek L, Brzosko M: Chronic Urticaria and Mild Arthritis Associated with Autoimmune Thyroid Disease: Successful Treatment with L-thyroxin. Acta Derm Venereol. 2007; 87: 263-4 (IF=1.927)
4. Milchert M, Brzosko M: Comment on "Polymyalgia rheumatica as the manifestation of unclassified aortitis". Mod Rheumatol. 2008;18: 427-8
5. Norman GL, Bialek A, Encabo S, Butkiewicz B, Wiechowska-Kozlowska A, Brzosko M, Shums Z, Milkiewicz P: Is prevalence of PBC underestimated in patients with systemic sclerosis? Dig Liver Dis. 2009; 41:762-4 (IF=2.972)
6. Prajs K, Bobrowska-Snarska D, Skała M, Brzosko M: Polyarteritis nodosa and Sjögren's syndrome: overlap syndrome. Rheumatol Int. 2010 May 18 (IF=1.493) [in print]
7. Bugajska J, Brzosko M, Jedryka-Góral A, Głuszko P, Zołnierczyk-Zreda D, Sagan A, Konarska M, Rell-Bakalarska M, Pazdur J, Zeidler H, Rihl M: Psychological stress in rheumatoid arthritis patients: a comparative Polish-German study: summary of the current conceptualization of the role of stress in rheumatoid arthritis. Autoimmun Rev. 2010 Feb;9(4):211-5 (IF=6,368)
8. Milchert M, Fisher K, Fliciński J, Ostanek L, Brzosko M: High prevalence of anti-beta-2 glycoprotein-I and anti-prothrombin antibodies in adult-onset Still's disease. Comment on "Portal vein thrombosis in adult-onset Still's disease: a case report and literature review" Rheumatol Int. 2010; 30: 1545-6 (IF=1.493)
9. Kremer JM, Blanco R, Brzosko M, Burgos-Vargas R, Halland AM, Vernon E, Ambs P, Fleischmann R: Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year. Arthritis Rheum. 2011; 63:609-21 (IF=7,332)
10. Krzysztalowska-Wawrzyniak M, Ostanek M, Clark J, Binczak-Kuleta A, Ostanek L, Kaczmarczyk M, Loniewska B, Wyrwicz LS, Brzosko M, Ciechanowicz A: The distribution of human endogenous retrovirus K-113 in health and autoimmune diseases in Poland. Rheumatology (Oxford). 2011;50: 1310-4.
4. Research Grants/Funds
1. The Project of the Sixth Framework Programme EU. Call 1 (FP62002-NMP-1). Advanced Interactive Materials by Design. Project coordinator: Prof. Andrzej Górak, University of Dortmund: Assessment of potential social benefits as a consequence of introducing new therapies. Quality of life, working ability and living costs in patients with rheumatoid arthritis. 2006-2008. Project performer.
2. Ministry of Science and Higher Education project NN402 472637: Ocena związku między stężeniem natiuretycznego peptydu typu B (BNP) i polimorfizmu T9-381C promotora genu prekursora BNP (NPPB), a uszkodzeniem prawej komory serca u chorych z śródmiąższową chorobą płuc w przebiegu twardziny układowej. Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, project director – project closed with doctor thesis.
3. Ministry of Science and Higher Education project NN402 445633: Polimorfizm promotora genu VEGF i stężenie VEGF jako czynniki ryzyka rozwoju miażdżycy tętnic kończyn dolnych u chorych na toczeń rumieniowaty układowy. Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, project director – project closed with doctor thesis.
4. Ministry of Science and Higher Education project NN402 178634: Stężenie propeptydu natriuretycznego typu C (CNP) oraz polimorfizm G2628A genu kodującego CNP jako czynniki ryzyka rozwoju zmian naczyniowych u chorych na twardzinę układową. Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, project director – project closed with doctor thesis.
5. Ministry of Science and Higher Education project NN402 189835: Association between BsmI vitamin D receptor gene polymorphism, vitamin D serum concentration and rheumatoid arthritis activity and progression. Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, 2008 r. project director, project closed with doctor thesis, congress presentations and publication: Association between BsmI vitamin D receptor gene polymorphism, vitamin D serum concentration and rheumatoid arthritis activity and progression. Ann. Acad. Med. Stetin. 2010; 56: 45-56.
6. Ministry of Science and Higher Education project NN402 473037: Ocena funkcji płytek krwi u chorych na twardzinę układową, Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, project director – ongoing.
7. Ministry of Science and Higher Education project NN402 266736: Prospektywna ocena wpływu wybranych statyn na progresję i występowanie zmian miażdżycowych w tętnicach szyjnych u chorych na toczeń rumieniowaty układowy, Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, project director – ongoing.
8. Ministry of Science and Higher Education project NN402 473237: Ocena związku między stężeniem interleukiny 23 i polimorfizmu genu receptora interleukiny 23, a aktywnością zapalną i przebiegiem choroby u chorych na seronegatywne spondyloartropatie, Department of Rheumatology and Internal Medicine of Pomeranian Medical University in Szczecin, project director – ongoing.