CV of Daniel L. Traber, Ph.D. 2007 Page XXX

CURRICULUM VITAE

Daniel L. Traber, Ph.D., F.C.C.M. August 2, 2007

Charles Robert Allen Professor of Anesthesiology and

Professor of Neuroscience and Cell Biology

Director of the Investigational Intensive Care Unit

The University of Texas Medical Branch

Galveston, TX 77555-0833


T A B L E OF C O N T E N T S

Page

Education 1

Professional and Teaching Experience 2

Visiting Professorships 3

Research Activities 6

Committee Responsibilities/ 9

Editorial and consultant responsibilities 10

Faculty Committees 13

Teaching Responsibilities 16

Fellows 17

Membership in Scientific Societies 20

Honors 23

Additional Information 24

Articles Published in Journals 25

Book Chapters 55

Editorials 62

Case Reports 64

Other Publications 65

Abstracts Published in Journal 68

Presentations at National and International Meetings--------------------------- --123


CV of Daniel L. Traber, Ph.D. 2007 EDUCATION Page XXX

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CV of Daniel L. Traber, Ph.D. 2007 PROFECIONAL AND TEACHING ACTIVITIES Page XXX

NAME: Daniel Lee Traber, Ph.D. DATE: April 6, 2009

PRESENT POSITION AND ADDRESS:

Charles Robert Allen Professor of Anesthesiology,

Professor of Physiology and Biophysics

Director of the Integrated Functional Laboratories

Director of the Investigational Intensive Care Unit

The University of Texas Medical Branch at Galveston

Galveston, Texas 77555 -1091

Chief of Anesthesiology Research and

Coordinator of Research

Shriners Hospital For Children

Galveston, Texas 77550

EDUCATION:

1956-1959 Biology and Chemistry, B.A., St. Mary's University,

San Antonio, Texas.

1960-1962 Physiology and Biochemistry, M.A., University of

Texas Medical Branch, Galveston, Texas

1962-1965 Physiology and Pharmacology, Ph.D., University of Texas

Medical Branch, Galveston, Texas.

1965-1966 Pharmacology, Postdoctoral Fellow, Ohio State University

College of Medicine, Columbus, Ohio.

PROFESSIONAL AND TEACHING EXPERIENCE:

1959-1960 Research Assistant Carter Physiology Laboratory

University of Texas Medical Branch

Galveston, Texas

1960-1961 Teaching and Research Department of Physiology

Assistant University of Texas Medical Branch

Galveston, Texas

1961-1965 National Institutes of Department of Physiology

Health Predoctoral Fellow University of Texas Medical Branch

Galveston, Texas

1965-1966 Postdoctoral Fellow Department of Pharmacology

Ohio State Univ College of Medici Columbus, Ohio

1966-1970 Assistant Professor Department of Physiology

University of Texas Medical Branch

Galveston, Texas

1966-1970 Research Assistant Department of Anesthesiology

Professor University of Texas Medical Branch

Galveston, Texas

1966-1970 Research Assistant Department of Anesthesiology

Professor Shriners Burns Institute

Galveston, Texas

1970-1971 Associate Professor Division of Anesthesiology

Shriners Burns Institute

Galveston, Texas

1970-1974 Associate Professor Department of Physiology

University of Texas Medical Branch

Galveston, Texas

1970-1974 Associate Professor Department of Anesthesiology

University of Texas Medical Branch

Galveston, Texas

1970-1999 Director Integrated Functional Laboratory

Univ. of Texas Medical Branch

Galveston, Texas

1971-Present Chief Division of Anesthesia Research

Shriners Burns Institute

Galveston, Texas

1974-Present Professor Department of Anesthesiology

Univ. of Texas Medical Branch

Galveston, Texas

1974-2005 Professor Dep of Physiology andBiophysics

Univ. of Texas Medical Branch

Galveston, Texas

1978-Present Coordinator of Research Shriners Burns Institute

Galveston, Texas

1997-Present Charles Robert Allen Professor Department of Anesthesiology

Univ. of Texas Medical Branch

2005 - Present Professor Dept. of Neuroscience and Cell Biology

Univ. of Texas Medical Branch

Galveston, Texas

VISITING PROFESSORSHIPS

1971 Ohio State University 1974 Ohio State University

Columbus, Ohio Columbus, Ohio

1976 Division de Estudios 1976 West Virginia University

Superiores de la Facultad de Medical Center

Medicine, U.N.A.M. Morgantown, West Virginia

1978 University of Oklahoma Health 1978 Petroleos Mexicanos

Science Center International Symposium on

Oklahoma City, Oklahoma Treatment of Burns

Mexico City, Mexico

1979 Albany Medical College of 1980 Louisiana State University

Union University School of Medicine

Albany, New York New Orleans, Louisiana

1981 University of Texas Health 1981 Ludwig-Boltzman Institute

Science Center for Experimental Traumatology

Houston, Texas Vienna, Austria

1981 De los hospitales militares 1983 Department of Physiology

IX Journada Medica International Texas Tech University

Santo Domingo, D. N Lubbock, Texas

1983-4 Ludwig-Boltzman Institute 1985 Department of Physiology

For Experimental Traumatology University of California

Vienna, Austria Davis, California

1985 Department of Anesthesiology 1986 Department of Physiology

Oregon Health Science Center Thomas Jefferson College of Medicine

Portland, Oregon Philadelphia, Pennsylvania

1986 Clinic for Anesthesiology 1986 Ludwig-Boltzman Institute

& Surgical Intensive Medicine for Experimental Traumatology

Westfälische Wilhelms Univ. Vienna, Austria

Münster, West Germany

1986 Department of Physiology 1986 Department of Anaesthesia

Loyola University University of Glasgow

College of Medicine Royal Infirmary

Chicago, Illinois Glasgow, Scotland

1987 Department of Anesthesia 1987 Department of Anaesthesia

Catholic University the Queen Victoria Hospital

Luvane, Belgium East Grinstead, England

1989 Ludwig-Boltzman Institute 1989 Tokyo Women's Medical College

For Experimental Traumatology Tokyo, Japan

Vienna, Austria

1991 Department of Anesthesiology 1991 Institute for Environmental Medicine

University of Geneva University of Pennsylvania

Geneva, Switzerland Philadelphia, Pennsylvania

1992 Department of Physiology 1993 Depart of Physiology. (MARK Program)

University of South Alabama University of North Dakota

Mobile, Alabama Grand Forks, North Dakota

1994 Department of Anesthesiology 1994 Department of Physiology

University of Vienna Louisiana State University Med. Center

Vienna, Austria Shreveport, Louisiana

1994 2nd Department of Surgery 1994 Department of Plastic Surgery

Yamaguchi, University Tokyo Woman’s Medical School

Ube, Japan Tokyo, Japan

1997 Clinic for Anesthesiology 1998 Department of Anesthesiology

& Surgical Intensive Medicine Hospital Charitie

Westfälische Wilhelms Univ. Humbolt University

Münster, Germany Berlin Germany

1998 Department of Anesthesiology 1998 Department of Anesthesiology

State University of Sao Paulo Federal University of Sao Paulo

Botucatu, Brazil Sao Paulo, Brazil

1998 Department of Experimental Surgery 1999 Department of Anesthesiology

State University of Sao Paulo Univ. of Massachusetts Medical Center

Sao Paulo, Brazil Worcester, Massachusetts

1999 Department of Medicine 2000 Department of Experimental Surgery

The Massachusetts General Hospital State University of Sao Paulo

Harvard Medical School Sao Paulo, Brazil

Boston, Massachusetts

2000 Department of Pulmonary Medicine 2001 Department of Critical Care Medicine

University of Washington McMaster’s University

Boise Idaho Hamilton Onterio, Canada

2002 Department of Critical Care Medicine 2004 Linus Pauling Institute

Erasma University Oregan State University

Brussels, Belgium Corvalis, Oregan

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CV of Daniel L. Traber, Ph.D. 2007 RESEARCH ACTIVITIES Page XXX

RESEARCH ACTIVITY

OTHER SUPPORT (Past 5 years)

NATIONAL INSTITUTE OF HEALTH

NIH-PO12 GM066312-01 (Traber, D. L.) 07/01/04-6/30/09

Pathophysiology of Lung Injury By Smoke Inhalation” Total Direct $6,583,080

NIH R01GM060688-01A1 (Traber, D. L.) 07/01/05-6/30/09

“The Role of Selectins in Burns and Lung Injury” Total Direct $780,000

NIH R01DK34817 (Wolfe, Robert) 07/01/99-6/30/04

“Role of Substrate Cycling in Energy Metabolism” Total Direct $318,087

NIH 1-T32-GM08256 (Herndon, D.N.) 07/1/06 – 6/30/11

(NIGMS-Trauma and Burn Research) Total Direct $721,028

Institutional National Research Service Award “Postdoctoral Training in Trauma And Burn”

NIH R01 AR49038 (Wolfe, Robert R.) 07/01/02-6/30/07

“Amino Acids and Muscle Protein Synthesis” Total Direct $327,581

NIH/NIAID UO1 AI53858-01(Peterson, Johnny) 09/01/02-8/03/07

“Development of Therapeutic Inhibitors to Anthrax Toxins Total Direct $291,428

NIH/SBIR 1-R43-HL68298 (Jagtap, Prakash) 11/01/01-7/31/02

“Novel PARS Inhibitor for Treatment of Smoke Inhalation Total Direct $56,000

and Burn Injury”

NIH/SBIR 1-R43-CA099849 (Salzman, Andrew) 4/15/03-12/31/03

“On a Novel Anti-Oxidant Catalyst to Treat IL-2 Toxicity” Total Direct $43,284

SHRINERS OF NORTH AMERICA

SBI 8450 (Traber, D.L.) 1/01/99-12/31/03

SPECIAL SHARED FACILITY- "Lung Lymph Laboratory" Total Direct $1,645,287

SBI 8954 (Traber, D.L.) 1/01/01-12/31/05

“Multi-Center Project: Effects of Nitric Oxide in Burns and Total Direct $1,247,774

Smoke Inhalation Injury”

SBI 8255 Startup Grant (Traber, D.L.) 06/01/03-5/31/04

“Multi-Center Project: Effects of Continuous Salbutamol Total Direct $20,072

Nebulization Therapy in Burns and Inhalation Injury”

SBI 8620 (Traber, D.L.) 01/01/02-12/31/04

“Use of Cyclooxygenase and Lipoxygenase Inhibitor Total Direct $117,705

in the Treatment of Smoke Inhalation and Burns”

SBI 8610 (Traber, D.L.) 01/01/00-12/31/02

“Burn and Smoke Inhalation Injuries Treated with Total Direct $503,764

Anti-Selectin Compounds”

SBI 8570 (Hawkins, H) 01/01/01-12/31/03

“Neurogenic Inflammatory Injury in the Airway” Total Direct $492,671

SBI 8530 (Zwischenberger, Joseph B.) 01/01/03-12/31/05

“A Perspective, Randomized Outcomes Study of Three Total Direct $618,180

Gentle Vent. Tech. (AVCO2R, HFPV, LTV) in a Clin. Rel. LD100 Smoke/Burn Sheep

ARDSModel to Assess Ventilator Free Days, Survival and Pathophysiology”

SBI 8310 (Schmalstieg, Frank C.) 01/01/03-12/3103

“Depression of p38 in the Pathogenesis of Acute Lung Total Direct $17,126

Injury in Smoke and Burn Injuries”

INDUSTRIAL

489440 Eli Lilly and Company 09/01/04-01/30/05

“Effect of Recombinant Human Activated Protein C (rhAPC) Total Direct $10,470

On Acute Lung Injury Associated With Smoke Inhalation In Sheep

Arphida Pharmaceuticals 01/01/04-12/01/06

“Use of a new antibiotic with anti-inflammatory Total Direct $96,639

properties in a Methicillin Resistance Staphylococcus Pneumonia”

Ferring Pharmaceuticals 04/28/04-08/01/04

The Use of AVP/P/V1a-selective Agonist in the Study #1 Total Direct $22,348

Treatment of Septic Shock

Ferring Pharmaceuticals Study #2 08/01/04-07/31/05

Total Direct $42,213

Ferring Pharmaceuticals Study #3 08/01/04-09/01/06

Total Direct $137,880

Ferring Pharmaceuticals Study #4 11/11/05-09/30/06

Comparison of the Effects of FE 202158 vs AVP Total Direct $200,889

Low Doses by Constant IV Infusion in a Sheep Model of Pneumonia-Induced

Sepsis Resuscitated Following as Early Goal-Directed Therapy Approach

Ferring Pharmaceuticals Study #5 06/01/07-07/01/08

Effect of arginine vasopressin (AVP) and of Total Direct $256,000

the selective V1a agonist FE 202158 in a sheep model of pneumonia-induced

sepsis using an early goal-directed therapy (EGDT)-like approach.

Jerini Pharmaceuticals 11/09/05 - 11/8/08

Studies with Bradykinin receptor blockade following thermal Total Direct $124,350

injury to the skin

Jerini Pharmaceuticals 3/01/07-12/01/07

Bradykinin (INCATIBANT) receptor blockade following thermal Total Direct $69,737

injury to the skin

American Heart Association (Enkhbaatar) 07/01/05-06/30/06

Role of nitric oxide in pathogenesis of cardiopulmonary Total Direct $124,000

derangements in sepsis induced by smoke inhalation and pneumonia

Arpida Pharmaceutical 08/10/05-08/10/06

Methicillin Resistant Staphylococci Study Total Direct $114,771

Ikaria Pharmaceutical

Effect of a hydrogen sulfide donor compound (IK-1001) in a murine 8/01/06 – 08/31/06

model of Combined Burn and Smoke Inhalation – Induced Total $41,632

Acute Lung Injury

Ikaria Pharmaceutical

Effect of a hydrogen sulfide donor compound (IK-1001) in a murine 9/01/06 – 12/31/06

model of Combined Burn and Smoke Inhalation – Induced Total $15,000

Acute Lung Injury

Ikaria Pharmaceutical

Effect of a hydrogen sulfide donor compound (IK-1001) in a ovine 1/01/07 – 09/01/07

model of Combined Burn and Smoke Inhalation – Induced Total $95,557

Acute Lung Injury

Ikaria Pharmaceutical

Effect of a hydrogen sulfide donor compound (IK-1001) in a an ovine 09/02/07 – 03/31/08

Model of Combined Burn and Smoke Inhalation – Induced Total $156,659

Acute Lung Injury

Pascoe Pharmaceutical 12/01/06-03/30/07

Effect of Vitamin C on survival rate in a mouse burn model Total Direct $20,250

Effect of Vitamin C on Cardioupulmonary function in burn/smoke sheep

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CV of Daniel L. Traber, Ph.D. 2007 Committee Memberships Page XXX

COMMITTEE RESPONSIBILITIES:

A. NATIONAL COMMITTEES

1984-Present Visiting Scientists for Minority Institutions, Federation of American

Societies for Experimental Biology

1987-1991 Hospital Information Systems Committee

Shriners Hospitals for Crippled Children

Chairman, Subcommittee for Database Managers

Executive Committee, 1988-1991

1988 AD HOC Member -National Advisory Council General Medical Sciences,

National Institutes of Health.

1989-1995 Consultant, Comprehensive Exam Part I,

Hematology/Immunology Task Force

National Board of Medical Examiners

Philadelphia, PA

1991-1995 Lung and Development Study Committee

Grant In Aid Application Reviewer

American Heart Association

National Center, Dallas, TX

1993-1997 Technical Advisory Committee

Tobacco and Health Research Institute

University of Kentucky

Lexington, Kentucky

1999 - Present Reviewer

American Institute for Biological Sciences

Sterling, Virginia

2000-Present Reviewer

Minority Health Research and Education Grant Program

State Coordinating Board

Austin, Texas

2001–2004 Reviewer

Lung, Resuscitation, and Respiration Study Group

Grant In Aid Application Reviewer

American Heart Association

National Center, Dallas, Texas

2006 - Present Reviewer

Cardiovascular and Pulmonary Study Section

Flight Attendents Medical Research Institute

Miami, Florida

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CV of Daniel L. Traber, Ph.D. 2007 SOCIETY MEMBERSHIP Page XXX

ConsultantshipS and Editorial Honors:

MEMBERSHIP ON EDITORIAL BOARDS

Editor - Clinical Science, 1998 - 2003

Editorial Committee Advances in Shock Research, 1983, 1988.

Editorial Board Circulatory Shock, 1988 - 1993.

Editorial Board - Shock, 1993 - Present.

Editorial Board - Critical Care Medicine, 1994 - Present.

Editorial Board - Journal of Burn Care & Research, 1995 - Present.

Editorial Board - Microcirculation – 2001 - Present

AD HOC MEMBERSHIPS ON EDITORIAL BOARDS

AD HOC Reviewer - American Journal of Physiology
Regulative, Integrative, and Comparative Physiology), 1989, 1990, 1993 to 2007

GI and Liver Physiology, 1992, 1994, 1999.

Lung, Cell & Molecular Physiology, 1999 to 2007.

Heart and Circulatory Physiology, 1989 to 2007

AD HOC Reviewer - American Journal of Respiratory and Critical Care Medicine, 1994 to 2003.

AD HOC Reviewer - Anesthesiology, 1998 to 2007.

AD HOC Reviewer - Circulatory Shock, 1987.

AD HOC Reviewer - Critical Care Medicine, 1990, 1991, 1992, 1993.

AD HOC Reviewer - Intensive Care Medicine, 1996, 1997, 1998, 2003-2007.

AD HOC Reviewer - Journal of Applied Physiology, 1987 to 2007.

AD HOC Reviewer - Journal of Burn Care and Rehabilitation, 1993, 1994, 1995.

AD HOC Reviewer - Journal of Experimental Medicine, 1992, 1994.

AD HOC Reviewer - Journal of International Anesthesia Research Society, 1968 to 2007.

AD HOC Reviewer - Journal of Laboratory and Clinical Medicine, 1994, 1996.

AD HOC Reviewer - Journal of Pharmacology and Experimental Therapeutics, 1983, 1992, 1995.

AD HOC Reviewer - Journal of Surgical Research, 1993, 1994, 1995, 2003-2007.

AD HOC Reviewer - Proceedings of The Society for Exp. Biology and Med., 1993, 1994, 1997.

AD HOC Reviewer - Medical Principals and Practice, 1993, 1995.

AD HOC Reviewer - Respiratory Physiology, 1993.

AD HOC Reviewer - Undersea Medicine, 1993.

AD HOC Reviewer - Surgery, 1992, 1993.

AD HOC Reviewer - Endotoxin Research, 1997,

AD HOC Reviewer - Journal of Clinical investigation, 1997

AD HOC Reviewer - Journal of Applied Nutrition, 1997

AD HOC Reviewer - Life Science, 1998.

AD HOC Reviewer – Microcirculation 1999, 2001.

AD HOC International Journal of Developmental Neuroscience, 2003-2004

AD HOC Reviewer/Site Visitor - National Institutes of Health, Ann Arbor, Michigan, 1987.

AD HOC Reviewer/Site Visitor - National Institutes of Health, San Diego, California, 1987.

AD HOC Reviewer - National Institutes of Health, Surgery Anesthesia and Trauma Study Section, 1991, 1999, 2000, 2003, 2004.

AD HOC Reviewer - National Institutes of Health – Special Study Section, 1999, 2000

AD HOC Reviewer/Site Visitor Temple Univ. - National Institutes of Health, Philadelphia, PA, 1999.

AD HOC Reviewer -National Institutes of Health -SSS-W study section (SBIR/STTR applications for cardiovascular devices)-2003.

AD HOC Reviewer -National Institutes of Health –Lung Injury, Repair and Remodeling Study Section (LIRR) 2004

AD HOC Reviewer -National Institutes of Health - ZRG1 RES-D 03-Special Study Section. 2004

AD HOC Reviewer - Henry Ford Hospital Research Application, 1988, 1989.

AD HOC Consultant - March of Dimes Research Fund, 1985.

AD HOC Consultant - Swiss National Fund, 1998, 1999.

AD HOC Consultant - Veterans Administration Hospital Grant Program, 1983, 1985, 1989, 1990, 1998, 1999.

AD HOC Consultant – Department of the Army Research and Material Command 1999 ton2003.

AD HOC Consultant – The Physicians’ Service Incorporated Foundation 2001.

Consultant - The United States Navy Medical Corps, 1991.

Consultant - Böhringer Ingelheim Pharmaceuticals, 1991, 1993, 1995.

Consultant - Smith Kline & Beecham Pharmaceuticals, 1991.