1
Table (E)T-1. Percentage of REM sleep muscle atonia and medication of the
33 Parkinson’s disease patients.
Sex PSG-confirmed RBD% of REM sleepDrug therapy (dosage regimen; number of
with atonia hours between last dose and bedtime)
F No 100Levodopa1 (100 mg five times a day; 1)
Ropinirole (6 mg qid; 1)
Amantadine (100 mg die; 17)
M No 99.6Pergolide (0.75 mg qid; 5)
F No 99.0Levodopa (100 mg qid; 1)
Pergolide (1 mg tid; 4)
F No 98.7Pergolide (1 mg tid; 5)
M No 98.2Stop since 3 months
M No 97.0Levodopa (150 mg five times a day; 1)
Bromocriptine (5 mg qid; 1)
F No 96.8Levodopa (50 mg tid; 5)
M No 96.7Pramipexole (1.5 mg tid; 1)
Selegiline (5 mg bid; 5)
M No 96.0Levodopa (200 mg die; 16)
F No 90.7Pramipexole (1.5 mg tid; 1)
Selegiline (5 mg bid; 11)
M No 89.3None
M No 87.5None
F No 83.6None
F No 81.2Selegiline (2.5 mg die; 15)
F No 79.5Levodopa (200 mg five times a day; 6)
Pramipexole (1.5 mg five times a day; 6)
M No 71.0Levodopa (150 mg tid; 5)
F No 71.0Levodopa (150 mg six times a day; 2)
M No 69.5Levodopa (100 mg five times a day; 5)
F No 60.4Levodopa (50 mg die; 1)
Pergolide (1 mg tid; 1)
M No 54.6Levodopa (50 mg bid; 5)
Pergolide (0.5 mg bid; 11)
F No 11.9Pramipexole (1 mg tid; 5)
M No 4.7Levodopa (50 mg six times a day; 1)
Pramipexole (1.5 mg tid; 1)
Selegiline (5 mg die; 13)
F Yes 75.8None
M Yes 56.4Levodopa (100 mg tid; 4)
Pergolide (0.25 mg tid; 4)
M Yes 51.2Levodopa (50 mg qid + 100 mg die; 1)
M Yes 17.0Amantadine (100 mg bid; 12)
M Yes 16.4Levodopa (150 mg eight times a day; 1)
M Yes 14.8Levodopa (100 mg qid; 1)
Pergolide (0.25 mg tid; 5)
M Yes 6.8Levodopa (150 mg qid; 1)
Selegiline (5 mg die; 15)
M Yes 6.0Ropinirole (1 mg qid; 1)
Selegiline (5 mg die; 15)
M Yes 2.4Levodopa (100 mg tid; 5)
Bromocriptine (5 mg tid; 5)
Selegiline (5 mg die; 15)
M Yes 0.4None
M Yes 0.0Levodopa (150 mg six times a day; 1)
Bromocriptine (1.5 mg tid; 5)
1 Carbidopa was administered in conjunction with levodopa for each patient. Abbreviations: PGS, polysomnography; RBD, REM sleep behavior disorder; %, percentage.
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