Definition of chronic conditions in childhood: national consensus in the Netherlands
Appendix 1
Overview of chronic conditions and clusters of chronic conditions using ICD-10 classification [31]
ICD-10 Code / A*Chapter I Certain infectious and parasitic diseases
A50 Congenital syphilis / + -A81 Atypical virus infections of central nervous system / +
B00 Herpesviral [herpes simplex] infections / +
B02 Herpes zoster / + -
B07 Viral warts / +
B18 Chronic viral hepatitis / +
B20-B24 Human immunodeficiency virus [HIV] disease / +
B25 Cytomegaloviral disease / + -
B27 Infectious mononucleosis / + -
B35 Dermatophytosis / +
B37 Candidiasis / + -
B44 Aspergillosis / +
B58 Toxoplasmosis / +
B59 Pneumocystosis / +
B90-B94 Sequelae of infectious and parasitic diseases / + -
Chapter II Neoplasms
D10-D36 Benign neoplasms / + -
D37-D48 Neoplasms of uncertain or unknown behaviour / +
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
D55-D59 Haemolytic anaemias (Anaemia due to enzyme disorders, Thalassaemia, Sickle-cell disorders, Acquired haemolytic anaemia) / +
D60 Acquired pure red cell aplasia [erythroblastopenia] / + -
D66 Hereditary factor VIII deficiency / +
D71 Functional disorders of polymorphonuclear neutrophils / +
D73 Diseases of spleen / + -
D80-D84 Immunodeficiencies / +
D86 Sarcoidosis / +
Chapter IV Endocrine, nutritional and metabolic diseases
E00/E03 congenital hypothyroidism / +
E01 Iodine-deficiency-related thyroid disorders and allied conditions / +
E05 Thyrotoxicosis [hyperthyroidism] / +
E06 Thyroiditis / +
E10-E14 Diabetes mellitus / +
E15 Nondiabetic hypoglycaemic coma / + -
E20 Hypoparathyroidism / +
E22 Hyperfunction of pituitary gland / +
E23 Hypofunction and other disorders of pituitary gland / +
E24 Cushing's syndrome / + -
E25 Adrenogenital disorders / +
ICD-10 Code / A*
E26 Hyperaldosteronism / +
E28 Ovarian dysfunction / + -
E29 Testicular dysfunction / +
E31 Polyglandular dysfunction / +
E32 Diseases of thymus / +
E64 Sequelae of malnutrition and other nutritional deficiencies / +
E65-E68 Obesity and other hyperalimentation / +
E70-E90Metabolic disorders / +
E73 Lactose intolerance / +
E74 Galactosemia / +
E84 Cystic fibrosis / +
E85 Amyloidosis / +
Chapter V Mental and behavioural disorders
F02-F03 Dementia / +
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances / +
F06 Other mental disorders due to brain damage and dysfunction and to physical disease / +
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction / +
F10-F19 Mental and behavioural disorders due to psychoactive substance use / + -
F20-F21 Schizophrenia en Schizotypical disorders / +
F22 Persistent delusional disorders / +
F25 Schizoaffective disorders / +
F29 Unspecified nonorganic psychosis / +
F31 Bipolar affective disorder [manic-depressive disorder] / +
F32 Depressive episode / + -
F33 Recurrent depressive disorder / +
F34-F39 Persistent mood [affective] disorders / +
F40-F41 Phobic anxiety disorders and other anxiety disorders / +
F42 Obsessive-compulsive disorder / +
F43 Reaction to severe stress, and adjustment disorders / + -
F44 Dissociative [conversion] disorders / + -
F45 Somatoform disorders / +
F48 Other neurotic disorders / +
F50 Eating disorders / +
F51 Nonorganic sleep disorders / + -
F52 Sexual dysfunction, not caused by organic disorder or disease / + -
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified / + -
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere / +
F64 Gender identity disorders / +
F70-F79 Mental retardation / +
F80-F89 Disorders of psychological development / +
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence / +
ICD-10 Code / A*
F90 Hyperkinetic disorders / +
F95 Tic disorders / + -
Chapter VI Diseases of the nervous system (G00-G99)
G04 Encephalitis, myelitis en encephalomyelitis / + -
G09 Sequelae of inflammatory diseases of central nervous system / +
G11 Hereditary ataxia / +
G12 Spinal muscular atrophy and related syndromes / +
G21 Secondary parkinsonism / + -
G24 Dystonia / + -
G35 Multiple sclerosis / +
G40 Epilepsy / +
G43 Migraine / +
G50-G59 Nerve, nerve root and plexus disorders / + -
G60 Hereditary and idiopathic neuropathy / +
G61 Inflammatory polyneuropathy / + -
G70 Myasthenia gravis and other myoneural disorders / +
G71 Primary disorders of muscles (M. Duchenne) / +
G72 Other myopathies / +
G80-G83 Cerebral palsy and other paralytic syndromes / +
G90 Disorders of autonomic nervous system / + -
G91 Hydrocephalus / + -
G92 Toxic encephalopathy / + -
Chapter VII Diseases of the eye and adnexa
H10 Conjunctivitis / + -
H15 Disorders of sclera / + -
H16 Keratitis / + -
H20 Iridocyclitis / + -
H30 Chorioretinal inflammation / +
H33 Retinal detachments and breaks / + -
H40 Glaucoma / + -
H46 Optic neuritis / + -
H49 Paralytische strabismus / +
H53 Visual disturbances (amblyopia) / +
H54 Blindness and low vision / +
H55 Nystagmus and other irregular eye movements / + -
Chapter VIII Diseases of the ear and mastoid process
H60 Otitis externa / + -
H65-H67 otitis media / + -
H68-H69 Eustachian salpingitis and obstruction and other disorders of Eustachian tube / + -
H70, H74, H75 Mastoiditis and related conditions / + -
H71 Cholesteatoma of middle ear / +
H72, H73 Perforation and other disorders of tympanic membrane / + -
H80 Otosclerosis / +
H81 Disorders of vestibular function / + -
H90, H91 Conductive, sensorineural and other hearing loss / + -
H92 Otalgia and effusion of ear / + -
ICD-10 Code
/ A*Chapter IX Diseases of the circulatory system
I01, I02 Acute rheumatic fever and Rheumatic chorea / +
I05-I09 Chronic rheumatic heart diseases / +
I10-I15 Hypertensive diseases / + -
I25 Chronic ischaemic heart disease / +
I26 Pulmonary embolism / + -
I34-I36 Nonrheumatic mitral valve, aortic valve, and tricuspid valve disorders / +
I37 Pulmonary valve disorders / +
I42 Cardiomyopathy / +
I44 Atrioventricular and left bundle-branch block / + -
I45 Other conduction disorders / +
I47 Paroxysmal tachycardia / + -
I48 Atrial fibrillation and flutter / +
I49 Other cardiac arrhythmias / +
I50 Heart failure / + -
I51 Complications and ill-defined descriptions of heart disease / +
I69 Sequelae of cerebrovascular disease / +
I70 Atherosclerosis / +
I71 Aortic aneurysm and dissection / + -
I78 Diseases of capillaries / + -
I83 Varicose veins of lower extremities / +
I84 Haemorrhoids / + -
I88 Nonspecific lymphadenitis / + -
Chapter X Diseases of the respiratory system
J30 Vasomotor and allergic rhinitis / + -
J31 Chronic rhinitis, nasopharyngitis and pharyngitis / +
J32 Chronic sinusitis / +
J33, J34 Nasal polyp and other disorders of nose and nasal sinuses / + -
J35 Chronic diseases of tonsils and adenoids / +
J37 Chronic laryngitis and laryngotracheitis / +
J41, J42 chronic bronchitis / +
J43 Emphysema / +
J45 Asthma / +
J47 Bronchiectasis / +
J60-J70 Lung diseases due to external agents / + / + -
J92 Pleural plaque / +
Chapter XI Diseases of the digestive system
K00-K14 Diseases of oral cavity, salivary glands and jaws / + -
K20 Oesophagitis / + -
K21 Gastro-oesophageal reflux disease / + -
K25-K28 Gastric ulcer, duodenal ulcer, peptic ulcer, and gastrojejunal ulcer / + -
K29 Gastritis and duodenitis / + -
K30 Dyspepsia / + -
K40-K44 Inguinal hernia, femoral hernia, umbilical hernia, ventral hernia, diaphragmatic hernia / + -
K50 Crohn's disease [regional enteritis] / +
ICD-10 Code / A*
K51 Ulcerative colitis / +
K55 Vascular disorders of intestine / + -
K57 Diverticular disease of intestine / +
K58 Irritable bowel syndrome / +
K60, K61 Fissure and fistula of anal and rectal regions / + -
K61 Abscess of anal and rectal regions / + -
K71 Toxic liver disease / + -
K74 Fibrosis and cirrhosis of liver / +
K90 Intestinal malabsorption (Coeliac disease) / + -
Chapter XII Diseases of the skin and subcutaneous tissue
L14 Bullous disorders in diseases classified elsewhere / + -
L20-L24 dermatitis (Atopic dermatitis, seborrhoeic dermatitis, diaper (napkin) dermatitis, allergic contact dermatitis, irritant contact dermatitis) / + / + -
L27 Dermatitis due to substances taken internally / + -
L28 Lichen simplex chronicus and prurigo / +
L29 Pruritus / + -
L40-L45 Papulosquamous disorders (e.g. Psoriasis) / + / + -
L52 Erythema nodosum / + -
L57 Skin changes due to chronic exposure to nonionizing radiation / +
L58 Radiodermatitis / + -
L60-L75 Disorders of skin appendages / + / + -
L80 Vitiligo / +
L82 Seborrhoeic keratosis / +
L83 Acanthosis nigricans / + -
L84 Corns and callosities / + -
L88 Pyoderma gangrenosum / + -
L89 Decubitus ulcer / + -
L90, L91 Atrophic and hypertrophic disorders of skin / + -
L92 Granulomatous disorders of skin and subcutaneous tissue / + -
L93 Lupus erythematosus / + -
Chapter XIII Diseases of the musculoskeletal system and connective tissue
M05-M10 Inflammatory polyarthropathies (rheumatoid arthritis) / +
M08 Juvenile arthritis / +
M15-M19 Arthrosis / +
M20 Acquired deformities of fingers and toes / +
M23 Internal derangement of knee / +
M30-M34 Systemic connective tissue disorders (incl Polyarteritis nodosa, lupus erythematosus, dermatopolymyositis, sclerosis) / +
M40-M42 Deforming dorsopathies (Kyphosis, lordosis, scoliosis, spinal osteochondrosis) / +
M45-M49 Spondylopathies (incl Bechterew) / +
M50, M51 Cervical and other intervertebral disc disorders / +
M54 Dorsalgia / + -
M60, M61 Myositis and calcification and ossification of muscle / + -
M65 Synovitis and tenosynovitis / + -
M70 Soft tissue disorders related to use, overuse and pressure / + -
M72 Fibroblastic disorders / +
ICD-10 Code / A*
M76 Enthesopathies of lower limb, excluding foot / + -
M80, M81 Osteoporosis with/without pathological fracture / + -
M84 Disorders of continuity of bone / + -
M87 Osteonecrosis / +
M88 Paget's disease of bone [osteitis deformans] / +
M91 Juvenile osteochondrosis of hip and pelvis / + -
Chapter XIV Diseases of the genitourinary system
N01-N08 Glomerular diseases (nephritic syndrome) / + / + -
N11-N14 Chronic tubulo-interstitial nephritis, obstructive and reflux uropathy and nephropathy / + / + -
N18 Chronic renal failure / +
N20, N21 Calculus of kidney, ureter and of lower urinary tract / + -
N25 Disorders resulting from impaired renal tubular function / + -
N27 Small kidney of unknown cause / +
N31 Neuromuscular dysfunction of bladder, not elsewhere classified / +
N35 Urethral stricture / +
N40 Hyperplasia of prostate / +
N43 Hydrocele and spermatocele / +
N46 Male infertility / +
N47 Redundant prepuce, phimosis and paraphimosis / + -
N60-N63 Disorders of breast (Benign dysplasia, inflammatory disorders, hypertrophy and unspecified lump) / + / + -
N75 Diseases of Bartholin's gland / + -
N80-N97 Noninflammatory disorders of female genital tract / + / + -
Chapter XVI Certain conditions originating in the perinatal period
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery / + -
P05 Slow fetal growth and fetal malnutrition / + -
P08 Disorders related to long gestation and high birth weight / + -
P25 Interstitial emphysema and related conditions originating in the perinatal period / + -
P27 Chronic respiratory disease originating in the perinatal period / + -
P29 Cardiovascular disorders originating in the perinatal period / + -
P35 Congenital viral diseases / + -
P37 Other congenital infectious and parasitic diseases / + -
P94 Disorders of muscle tone of newborn / + -
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
Q00-Q05 Congenital malformations of the nervous system (Anencephaly, Encephalocele, Microcephaly, Congenital hydrocephalus, Spina bifida) / +
Q10-Q16 Congenital malformations of eye, ear, face and neck (craniofacial anomalies) / +
Q20-Q28 Congenital malformations of the circulatory system (o.a. transposition of great vessels) / +
Q30-Q34 Congenital malformations of the respiratory system (nose, larynx, trachea and bronchus, and lung) / + / + -
Q35-Q37 Cleft lip and cleft palate / + -
ICD-10 Code / A*
Q39, Q41-42, Q44 congenital malformations of the digestive system / + -
Q50-Q56 Congenital malformations of genital organs / + / + -
Q60-Q62 Congenital malformations of the urinary system / + -
Q65-Q67 Congenital malformations and deformations of the hip, feet, head, face, spine and chest / + -
Q69 Polydactyly / + -
Q70 Syndactyly / + -
Q71-Q73 Reduction defects of limbs / +
Q76 Congenital malformations of spine and bony thorax / + -
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine / + -
Q80 Congenital ichthyosis / +
Q81 Epidermolysis bullosa / +
Q82 Other congenital malformations of skin / +
Q83 Congenital malformations of breast / + -
Q84 Other congenital malformations of integument / +
Q85 Phakomatoses, not elsewhere classified / + -
Q90 Down's syndrome / +
Q91 Edwards' syndrome and Patau's syndrome / +
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified / +
Q93 Monosomies and deletions from the autosomes, not elsewhere classified / +
Q95 Balanced rearrangements and structural markers, not elsewhere classified / +
Q96 Turner's syndrome / +
Q97-Q99 Other chromosome abnormalities / +
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
R02 Gangrene, not elsewhere classified / +
R06 Abnormalities of breathing / + -
R10-R19 Symptoms and signs involving the digestive system and abdomen / + -
R20-R22 Symptoms and signs involving the skin and subcutaneous tissue / + -
R25-R27 Symptoms and signs involving the nervous and musculoskeletal systems / + -
R30-R36 Symptoms and signs involving the urinary system / + -
R40-R44 Symptoms and signs involving cognition, perception, emotional state and behaviour / + -
R47-R49 Symptoms and signs involving speech and voice / + / + -
R50-53, R59-64 General symptoms and signs (fever, headache, pain, malaise and fatigue, Enlarged lymph nodes, oedema, Hyperhidrosis, Cachexia) / + -
R70-R75 Abnormal findings on examination of blood, without diagnosis / + -
R80, R81 Isolated proteinuria and Glycosuria / + -
ICD-10 Code / A*
R83, R84 Abnormal findings in cerebrospinal fluid and in specimens from respiratory organs and thorax / + -
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis / + -
S06 Intracranial injury / + -
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source / + -
T67, T70 Effects of heat and light and of air pressure and water pressure / + -
T68 Hypothermia / + -
T74 Maltreatment syndromes / + -
T80-T87 Complications of surgical and medical care, not elsewhere classified / + / + -
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes / +
Y10-Y19 Event of undetermined intent (Poisoning by and exposure to) / + -
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use / + -
Y61-Y64 Misadventures to patients during surgical and medical care / + -
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use / + -
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure / + -
Y85-Y88 Sequelae of external causes of morbidity and mortality ((transport) accidents) / +
*A: Chronic condition: + chronic condition in childhood, +- condition can be chronic, depending on its duration.
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