Jiming Kong, MD, PhD

Professor

Department of Human Anatomy and Cell Science

Faculty of Medicine, University of Manitoba

745 Bannatyne Avenue

Winnipeg, Manitoba R3E 0J9 Canada

Telephone:(204)977-5601, Mobile: (204)890-5601

Fax: (204)789-3920

Education

PhD (1994), Department of Human Anatomy, The First Military Medical University, Guangzhou, China. Supervisors: Professors Shizhen Zhong and Yaomin Hu

MSc (1986), Department of Human Anatomy, The First Military Medical University, Guangzhou, China. Supervisors: Professors Shizhen Zhong and Bo Sun

MD (1983), Luzhou Medical College, Sichuan, China

Professional experience

1)Professor with Tenure, April 1, 2011 - Present, Department of Human Anatomy and Cell Science, University of Manitoba

2)Adjunct Professor, July 1, 2012 – Present, Department of Psychiatry, University of Manitoba

3)Adjunct professor, Nov 2009 – Present, Biology Department, University of Winnipeg

4)Associate Professor with Tenure, July 1, 2008 – March 2011. Department of Human Anatomy and Cell Science, University of Manitoba

5)Director, April 2007- Present, Subcellular Analysis Center, Faculty of Medicine, University of Manitoba.

6)Associate Professor, April 1, 2006 – March 2011. Department of Human Anatomy and Cell Science, University of Manitoba

7)Assistant Professor, July 2002 – March 2006, Department of Human Anatomy and Cell Science, University of Manitoba

8)Adjunct Assistant Professor, July 2002 – Present. Division of Neurodegenerative Disorders, St. Boniface General Hospital Research Center, Winnipeg, Manitoba

9)Postdoctoral Fellow, July 2000 – June 2002, Dr. Jonathan D. Geiger’s Laboratory, Department of Pharmacology & Therapeutics, University of Manitoba, Winnipeg, MB, Canada

10)Postdoctoral Fellow, Feb. 1998 - June 2000, Dr. Judy E. Anderson’s Laboratory, Department of Anatomy and Cell Sciences, University of Manitoba Winnipeg, MB, Canada

11)Postdoctoral Fellow, Mar. 1995 - Jan. 1998, Dr. Zuoshang Xu’s Laboratory, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA

12)World Health Organization Visiting Scholar, Oct. 1994 - Mar. 1995, Dr. Stanley E. Appel's Lab, Department of Neurology, Baylor College of Medicine, Houston, TX, USA

13)Associate Professor, Dec. 1992 – Oct. 1994, Department of Human Anatomy, The First Military Medical University, Guangzhou, PR China

14)Lecturer, Feb. 1989 – Dec.1992, Department of Human Anatomy, The First Military Medical University, Guangzhou, PR China.

15)Teaching Assistant, Aug. 1986 - Jan. 1989, Department of Human Anatomy, The First Military Medical University, Guangzhou, PR China.

Publications

Refereed papers

  1. Guan T, Li C, Zhang L, Chen X, Li XM, Xiao L and Kong J. (2014) Cerebral ischemic preconditioning aggravates death of oligodendrocyte precursor cells. In submission.
  2. Lyubetska H, Zhang L, Kong J and Vrontakis M. (2015) An Elevated Level of Circulating Galanin Promotes Developmental Expression of Myelin Basic Protein in the Mouse Brain. Neuroscience. 284: 581-589
  3. Zhu S, Wang H, Shi R, Zhang R, Wang J, Kong L, Sun Y, He J, Kong J, Wang JF, Li XM. (2014) Chronic Phencyclidine Induces Inflammatory Responses and Activates GSK3β in Mice. Neurochem Res. 2014 Oct 1. [Epub ahead of print]. PMID: 25270429
  4. Shi R, Zhu S, Li V, Gibson SB, Xu X, Kong J. (2014)BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke.CNS Neurosci Ther. 2014 Sep 17. doi: 10.1111/cns.12325. [Epub ahead of print]. PMID: 25230377
  5. Li W, Guan T, Zhang X, Wang Z, Wang M, Zhong W, Feng H, Xing M and Kong J. (2014) The effect of layer-by-layer assembly coating on the proliferation and differentiation of neural stem cells.ACS Applied Materials & InterfacesPublication Date (Web): October 27, 2014 (Article)DOI: 10.1021/am504456t
  6. Zhang X, Bian X and Kong J. (2014)The proapoptotic protein BNIP3 interacts with VDAC to induce mitochondrial release of endonuclease G. PLoS One, 2014 Dec 1;9(12):e113642. doi: 10.1371/journal.pone.0113642. eCollection 2014.
  7. Wang J, Zhang Y, Xu H, Zhu S, Wang H, He J,Zhang H, Guo H, Kong J, Huang Q, Li XM. (2014) Fluoxetine Improves Behavioral Performance by Suppressing the Production of Soluble β-Amyloid in APP/PS1 Mice.Current Alzheimer Research 11 (7), 672-680
  8. Wang J, Qiao J, Zhang Y, Wang H, Zhu S, Zhang H, Hartle K, Guo H, Guo W, He J, Kong J, Huang Q and Li XM. (2014)Desvenlafaxine prevents white matter injury and improves the decreased phosphorylation of the rate‐limiting enzyme of cholesterol synthesis in a chronic mouse model of depression. Journal of neurochemistry2014 Jun 17. doi: 10.1111/jnc.12792. [Epub ahead of print]
  9. Chen J, Qiu X, Wang L, Zhong W, Kong J, Xing M. (2014) Free‐Standing Cell Sheet Assembled with Ultrathin Extracellular Matrix as an Innovative Approach for Biomimetic Tissues. Advanced Functional Materials 24: 2216-2223.DOI: 10.1002/adfm.201302949
  10. Wang J, Zhu S, Wang H, He J, Zhang Y, Adilijiang A, Zhang H, Hartle K, Guo H, Kong J, Huang Q, Li XM.( 2014) Astrocyte-dependent Protective Effect of Quetiapine on GABAergic Neuron is Associated with the Prevention of Anxiety-like Behaviors in Aging Mice after Long-term Treatment.Journal of Neurochemistry. 05/2014; DOI:10.1111/jnc.12771
  11. Zhu S, Wang J, Zhang Y, Li V, Kong J, He J and Li XM(2014) Unpredictable chronic mild stress induces anxiety and depression-like behaviours and inactivates AMP-activated protein kinase in mice. Brain research, 2014 Aug 12;1576:81-90. doi: 10.1016/j.brainres.2014.06.002. Epub 2014 Jun 24.
  12. Zhang H, Zhang Y, Xu H, Wang L, Adilijiang A, Wang J, Hartle K, Zhang Z, Zhang D, Tan Q, Kong J, Huang Q, Li XM. (2014) Olanzapine ameliorates neuropathological changes and increases IGF-1 expression in frontal cortex of C57BL/6 mice exposed to cuprizone.Psychiatry Res. 2014 Feb 22. pii: S0165-1781(14)00137-1. doi: 10.1016/j.psychres.2014.02.019. [Epub ahead of print]PMID: 24613202
  13. Zhang GH, Zhao YN, Li XM and Kong J. (2014) Fetal cell microchimerism in the maternal mouse spinal cord. Neurosci Bull 30(1):81-9. doi: 10.1007/s12264-013-1392-1. Epub 2013 Dec 17.
  14. Hayes K, Buist R, Vincent TJ, Thiessen JD, Zhang Y, Zhang H, Wang J, Summers AR, Kong J, Li XM, Martin M. (2014) Comparison of manual and semi-automated segmentation methods to evaluate hippocampus volume in APP and PS1 transgenic mice obtained via in vivo magnetic resonance imaging. J Neurosci Methods.2014 Jan 15;221:103-11. doi: 10.1016/j.jneumeth.2013.09.014. Epub 2013 Oct 1. PMID: 24091139
  15. He J, Qiao JP , Zhu SH, Xue MZ, Chen WW , Wang XC, Tempier A , Huang QJ, Kong J and Li XM. (2013) Serum -amyloid peptide levels spike in the early stage of Alzheimer’s disease phenotype in an APP/PS1 double transgenic mouse model.Current Alzheimer Research, 10, 979-986. PMID24117120
  16. Guan T, Liu Q, Qian Y, Yang H, Kong J, Kou J, Yu B. (2013) Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse model of experimental stroke. Eur J Pharmacol.2013 Aug 15;714(1-3):303-11. doi: 10.1016/j.ejphar.2013.07.036. Epub 2013 Jul 30. PMID23911884
  17. Thiessen JD, Zhang Y, Zhang H, Wang L, Buist R, Del Bigio MR, Kong J, Li XM and Martin M. (2013) Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination. NMR in Biomedicine2013 Nov;26(11):1562-81. doi: 10.1002/nbm.2992. Epub 2013 Aug 13.PMID: 23943390
  18. Li C, Guan T, Chen X, Li W, Cai Q, Niu J, Xiao L, Kong J. (2013) BNIP3 mediates pre-myelinating oligodendrocyte cell death in hypoxia and ischemia. Journal of Neurochemistry 2013 Nov;127(3):426-33. doi: 10.1111/jnc.12314. Epub 2013 Jun 5. PMID: 23692407
  19. Yu D, Li M, Ni B, Zhang Z and Kong J. (2013) Induction of neuronal mitophagy in acute spinal cord injury in rats. Neurotoxicity Research2013 Nov;24(4):512-22. doi: 10.1007/s12640-013-9397-0. Epub 2013 Apr 30. PMID: 23637053.
  20. Chen J, Ouyang J, Kong J, Zhong W and Xing, M. (2013) Photo-crosslinked and pH sensitive biodegradable micelles for doxorubicin delivery. Applied Materials & Interfaces5(8):3108-17.Epub 2013 Apr 15. PMID: 23530535
  21. Zhang H, Zhang Y, Xu H, Huang Q, Wang L, Zhao J, Wang J, Zhang Z, Tan Q, Kong J, Li X-M. (2013) Locomotor activity and anxiety status, but not spatial working memory, are affected in short-term cuprizone-exposed mice. Neurosci Bull 2013 Oct;29(5):633-41. doi: 10.1007/s12264-013-1369-0. Epub 2013 Aug 29.PMID: 23990221
  22. Chen X, Guan T, Zhang X, Li C, Shang H, Cui L, Li XM and Kong J. (2013) S-Nitrosylated Protein Disulphide Isomerase contributes to Mutant SOD1 aggregates in Amyotrophic Lateral Sclerosis. Journal of Neurochemistry 124(1):45-58.doi: 10.1111/jnc.12046.
  23. Tempier A, He J, Zhu S, Zhang R, Kong L, Tan Q, Luo H, Kong J, Li XM. (2013) Quetiapine modulates conditioned anxiety and alternation behavior in Alzheimer's transgenic mice. Current Alzheimer research 10:199-206, PMID: 22950914
  24. Chen X, Guan T, Li C, Shang H, Cui L, Li XM and Kong J. (2012) SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI). Journal of Neuroinflammation12;9:237. doi: 10.1186/1742-2094-9-237.PMID: 23061969
  25. Mei F, Guo S, He Y, Wang L, Wang H, Niu J, Kong J, Li X, Wu Y, Xiao L. (2012) Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation. PLoS One. 7(8):e42746. doi: 10.1371/journal.pone.0042746.
  26. Chen X, Guo C, Kong J. (2012) Oxidative stress in neurodegenerative diseases. Neural Regeneration Research, 7(5): 376-385.
  27. Lu Y, Wang L, He M, Huang W, Li H, Wang Y, Kong J, Qi S, Ouyang J, Qiu X. (2012) Nix protein positively regulates NF-κB activation in gliomas. PLoS One. 7(9):e44559. doi: 10.1371/journal.pone.0044559.
  28. Zhu, S., He, J., Zhang, R., Kong, L., Tempier, L., Kong, J. & Li, X. M. (2012). Therapeutic effects of quetiapine on memory deficit and brain beta-amyloid plaque pathology in a transgenic mouse model of Alzheimer's disease. Current Alzheimer research(2012 Aug 30. Epub ahead of print)
  29. Shi R; Weng J; Zhao L, Li, XM; Gao TM and Kong J. (2012) Excessive autophagy contributes to neuron death in cerebral ischemia. CNS Neuroscience and Therapeutics 18 (3): 250–260.
  30. Zhang R, He J, Zhu S, Zhang H, Wang H, Adilijiang A, Kong L, Wang J, Kong J, Tan Q, XM Li. (2012) Myelination deficit in a phencyclidine-induced neurodevelopmental model of schizophrenia. Brain Res 1469: 136–143
  31. Zhang L; Wu Y; Schroedter I; Kong J; Vrontakis M. (2012)Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model. PLoS ONE 7(3): e33901. doi:10.1371/journal.pone.0033901.
  32. Bi X, Zhang Y, Yan B, Fang S, He J, Zhang D, Kong J, Tan Q and Li XM. (2102) Quetiapine prevents oligodendrocyte and myelin losses and promotes maturation of oligodendrocyte progenitors in the hippocampus of global cerebral ischemia mice. Journal of Neurochemistry 123:14-20.
  33. Zhang Y, Zhang H, Wang L, Jiang W, Xu H, Xiao L, Bi X, Wang J, Zhu S, Zhang R, He J, Tan Q, Zhang D, Kong J, Li XM. (2012) Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination. Schizophrenia Research. 2012 Jun;138(1):8-17.
  34. Chen X, Shang H, Qiu X, Fujiwara N, Cui L, Li XM, Gao TM and Kong J. (2012) Oxidative modification of cysteine 111 promotes disulfide bond-independent aggregation of SOD1. Neurochemical Research 37(4): 835-845.
  35. Niu J, Wang L, Liu S, Li C, Kong J, Shen HY, Xiao L. (2012) An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells. J Neurosci Methods. Jul 30;209(1):241-9. doi: 10.1016/j.jneumeth.
  36. Zou ZY, Wang XN, Liu MS, Sun Q, Li XG, Cui LY, Kong J. (2012) Identification of a novel missense mutation in angiogenin in a Chinese amyotrophic lateral sclerosis cohort. Amyotrophic Lateral Sclerosis. 13(3):270-5
  37. Chen WW, Yu HL, Fan HB, Zhang CC, Zhang M, Zhang CY, Cheng YB, Kong J, Liu CF, Geng D, Xu XS. (2012) RIP1 mediates the protection of geldanamycin on neuronal necroptosis induced by oxygen-glucose deprivation combined with zVAD in primary cortical neurons. Journal of Neurochemistry 120 (1): 70–77
  38. Chen J, Zehtabi F, Ouyang J, Kong J, Zhong W and Xing MQ. (2012) Reducible self-assembled micelles for enhanced intracellular delivery of doxorubicin. Journal of Materials Chemistry22 (15): 7121-7129. DOI: 10.1039/C2JM15277K
  39. Chen J, Qiu X, Ouyang J, Kong J, Zhong W, and Xing MQ. (2011) pH and Reduction Dual-Sensitive Copolymeric Micelles for Intracellular Doxorubicin Delivery Biomacromolecules, 2011, 12 (10), 3601–3611
  40. Chen J, Zhou B, Li Q, Ouyang J, Kong J, Zhong W and Xing MQ. (2011) PLLA-PEG-TCH-labeled bioactive molecule nanofibers for tissue engineering. International Journal of Nanomedicine 2011: 1–10.
  41. Wang Y, Zhang Y, He J, Zhang H, Xiao L, Kong J and Li MX. (2011) Hyperforin promotes mitochondrial function and development of oligodendrocytes. Journal of Neurochemistry 119(3):555-568.
  42. Zhang Z, Shi R, Weng J, Xu X, Li XM, Gao TM and Kong J. (2011) The proapoptotic member of the Bcl-2 family BNIP3 is a mediator of caspase-independent neuronal death in excitotoxicity. FEBS Journal 278 134–142.
  43. Shao WH, Li C, Chen L, Qiu X, Zhang W, Huang CX, Xia L, Kong J, Tang Y. (2010) Stereological investigation of age-related changes of the capillaries in white matter. The Anatomical Record 293:1400–1407.
  44. Niu JQ, Mei F, Li N,, Wang HZ, Li XM, Kong JandXiao L. (2010) Haloperidol promotes proliferation but inhibits differentiation in rat oligodendrocyte progenitor cell cultures. Biochemistry and Cell Biology88:611-620.
  45. Wang H, Xu H, Niu J, Li XM, Kong J, Cai W and Xiao L. (2010) Haloperidol activates quiescent oligodendroglia precursor cells in the white matter of adult mouse brain. Schizophrenia Research 119:164-174.
  46. Fang S, Yan B, Wang D, Bi X, Zhang Y, He J, Yang Y, Xu H, Kong J, Wu J, and Li XM. (2010) Chronic effects of venlafaxine on synaptophysin and neuronal cell adhesion molecule in the hippocampus of cerebral ischemic mice. Biochemistry and Cell Biology 88:655-683.
  47. Bi X, Yan B, Fang S, He J, Li XMandKong J. (2009) Quetiapine regulates neurogenesis in ischemic mice by inhibiting NF-kB p65/p50 expression. Neurological Research 31:159-166.
  48. Zhao ST, Chen M, Li SJ, Zhang MH, Li BX, Das M, Bean J, Kong J, Zhu XH, Gao TM. (2009) Mitochondrial BNIP3 upregulation precedes endonuclease G translocation in hippocampal neuronal death following oxygen-glucose deprivation. BMC Neuroscience 10:113
  49. He J, Kong J, Tan QR and Li XM. (2009) Neuroprotective effect of atypical antipsychotics in cognitive and non-cognitive behavioral impairment in animal models. Cell Adhesion and Migration 3: 129-137.
  50. Chen M, Sun HY, Li SJ, Das M, Kong J, Gao TM. (2009) Nitric oxide as an upstream signal of p38 mediates hypoxia/reoxygenation-induced neuronal death. Neurosignals 17:162-168.
  51. Yu Y, He J, Zhang Y, Luo H, Zhu S, Yang Y, Zhao T, Wu J, Huang Y, Kong J, Tan Q, Li XM. (2009) Increased hippocampal neurogenesis in the progressive stage of Alzheimer’s disease phenotype in an APP/PS1 double transgenic mouse model. Hippocampus 19:1247–1253.
  52. Zhang Y, Xu H, Jiang W, Xiao L, Yan B, He J, Wang Ya, Bi X, Li X, Kong Jand Li XM. (2008) Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse. Schizophrenia Research 106:182-191.
  53. Xu HY, Wang H, Zhuang L, Yan B, Yu Y, Wei Z, Zhang Y, Dyck LE, Richardson SJ, He J, Li X, Kong J and Li XM. (2008) Demonstration of an anti-oxidative stress mechanism of quetiapine: Implications for the treatment of Alzheimer’s disease. FEBS Journal, 275(14):3718-3728.
  54. Chen Y, McMillan-Ward E, Kong J, Israels SJ and Gibson SB. (2008) Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death and Differentiation, 15:171-182.
  55. Zhang Z, Yang X, Zhang S, Ma X and Kong J. (2007) BNIP3 upregulation and EndoG translocaiton in delayed neuronal death in stroke and in hypoxia. Stroke 38 (5), 1606-1613
  56. Zhang S, Zhang Z, Sandhu G, Ma X, Yang X, Geiger JD and Kong J. (2007) Evidence of oxidative stress-induced BNIP3 expression in amyloid beta neurotoxicity. Brain Research 1138:221-230.
  57. Chen Y, McMillian-Ward E, Kong J, Isreals SJ and Gibson S. (2007) Mitochondrial electron transport chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. Journal of Cell Science 120: 4155-4166.
  58. Yan B, Bi X, He J, Zhang Y, Thakur S, Xu H, Gendron A, Kong J, Li XM. (2007)Quetiapine attenuates spatial memory impairment and hippocampal neurodegeneration induced by bilateral common carotid artery occlusion in mice. Life Science 81(5):353-361.
  59. Xu X, Chua CC, Kong J, Kostrzewa RM, Kumaraguru U, Hamdy RC and Chua BHL. (2007) Necrostatin-1 protects against glutamate-induced GSH depletion and caspase-independent cell death in HT-22 cells. Journal of Neurochemistry, 103:2004-2014.
  60. Yan B, He J, Xu H, Zhang Y, Bi X, Thakur S, Gendron A, Kong J and Li XM. (2007) Quetiapine attenuates the depressive and anxiolytic-like behavioural changes induced by global cerebral ischemia in mice. Behavioural Brain Research 182:36-41.
  61. Wozniak AC, Kong J, Bock E, Pilipowicz O and Anderson JE. (2005) Signalling satellite-cell activation in skeletal muscle: Markers, models, stretch, and potential alternate pathways. Muscle and Nerve 31(3):283-300.
  62. Xu ZS, Jung C, Higgins C, Levine J and Kong J. (2004) Mitochondrial degeneration in ALS. Journal of Bioenergetics and Biomembranes, 36(4):395-400.
  63. Kong J, Shepel PN, Holden CP, Mackiewicz M, Pack AI and Geiger JD. (2002) Brain glycogen decreases with increased periods of wakefulness - implications for homeostatic drive to sleep. The Journal of Neuroscience 22:5581-5587.
  64. Anderson JE and Kong J. (2002) Acetylcholine receptors at the neuromuscular junction of regenerated muscle fibers. Muscle and Nerve 25(2):300-1.
  65. Kong J and Anderson JE. (2001) Dynamic restoration of dystrophin to dystrophin-deficient myotubes. Muscle and Nerve 24:77-88.
  66. Kong J and Xu ZS. (2000) Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis. Neuroscience Letters 281:72-74
  67. Levine J, Kong J, Nadler M and Xu ZS. (1999) Astrocytes interact intimately with degenerating motor neurons during the course of disease progression in amyotrophic lateral sclerosis (ALS). Glia 28:215-224.
  68. Kong J and Anderson JE. (1999) Dystrophin is required for organizing large acetylcholine receptor aggregates in muscle regeneration. Brain Research 839:298-304.
  69. Kong J and Xu ZS. (1999) Peripheral axotomy slows motor neuron degeneration in a transgenic mouse line expressing mutant SOD1 G93A. Journal of Comparative Neurology 412(2):373-380.
  70. Kong J and Xu ZS. (1998) Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. The Journal of Neuroscience 18(9):3241-3250.
  71. Kong J, Tung VWY, Aghajanian J and Xu ZS. (1998) Antagonistic roles of neurofilament subunits NF-H and NF-M against NF-L in shaping dendritic arborization in spinal motor neurons. The Journal of Cell Biology 140(5):1167-1176.
  72. 孔吉明，钟世镇，胡耀民，李忠华. 周围神经损伤所致感觉神经元胞体死亡的保护. 中华显微外科杂志，1995，18(4):269-271
  73. 孔吉明,钟世镇,胡耀民.运动神经营养因子研究现状.中国临床解剖学杂志, 1995,13(1):68- 71
  74. 孔吉明,钟世镇,胡耀民.靶源性运动神经营养因子.神经科学,1995,2(1):41-44
  75. 陈强，胡耀民，钟世镇，孔吉明. 异体腹主动脉桥接周围神经缺损的实验研究. 中华显微外科杂志，1994，17(4):273-276
  76. 杨振祥,刘志斌,孔吉明,钟世镇.神经组织匀浆对面神经再生影响的实验研究.中国临床解剖学杂志, 1994,12(3):214-217
  77. 胡耀民,李汉云,秦建强,孔吉明,刘大庸,钟世镇.骨骼肌桥接周围神经缺损效果的实验观察.中国临床解剖学杂志,1991,9(3):165-167
  78. 钟世镇,孔吉明.显微外科基础和临床研究进展.前卫医学情报,1991,7(5):165-166
  79. Kong J, Wang GY and Zhong SZ. (1991) The role of laminin in peripheral nerve regeneration: An in vivo experimental study in the rats. Neuroscience Letter (Supplement) 41:5.
  80. Zhong SZ and Kong J. (1991) Basic and clinical studies in microsurgery. Chinese Medical Journal 104:799- 802.
  81. Zhong SZ, Kong J and Wang Q. (1990) Relevant knowledge on the research of clinical anatomy. Surgical and Radiological Anatomy 12:79-81.
  82. 钟世镇,孔吉明.骨骼肌桥接神经缺损研究的进展.中国临床解剖学杂志,1989,7(1):51-54
  83. Zhong SZ and Kong J. Microsurgical anatomy in China. (1989) Surgical and Radiological Anatomy 11:115-122.
  84. Xu DC, Kong J and Zhong SZ. (1989) The ascending branch of the lateral circumflex femoral artery. A new supply for vascularized iliac transplantation. Surgical and Radiological Anatomy 11:263-264.
  85. Xu DC, Zhong SZ, Kong J, Wang GY, Liu MZ, Luo LS and Gao JH. Applied anatomy of the anterolateral femoral flap. (1988) Plastic and Reconstructive Surgery 82:305-310.
  86. 戴绍业,林道贤,李秀生,韩震,孔吉明,钟世镇.用肌桥和神经移植尺神经术后早期电生理的比较. 中国临床解剖学杂志,1988,6(3):174-176
  87. 原林,钟世镇,孙博,孔吉明.双侧胸锁乳突肌单头旋转肌皮瓣再造舌的解剖学基础. 中华显微外科杂志,1988,11(2):92-94
  88. 钟世镇,孔吉明.用骨骼肌桥接长段神经缺损的新术式.前卫医学情报,1988,4(3):99-101
  89. 孔吉明,钟世镇.用肌桥桥接周围神经缺损的远期观察. 中国临床解剖学杂志, 1988,6(2):76-78
  90. 孔吉明,钟世镇,孙博.用骨骼肌引导神经再生的实验模型的制备和应用. 临床解剖学杂志1987,5:17-19
  91. 戴绍业,林道贤,忻元培,孔吉明,钟世镇,韩震.肌桥修复坐骨神经缺损一例初步报告. 临床解剖学杂志,1987,5(4):231-232
  92. 孔吉明,钟世镇,孙博,何蕴韶.神经溃及再生的组织化学法评价. 临床解剖学杂志, 1987,5(1):20-21
  93. 孔吉明,钟世镇,孙博,朱盛修.用骨骼肌桥接周围神经缺损的实验研究. 中华显微外科杂志, 1986,9(2):68-70
  94. Kong J, Zhong S, Sun B, Zhu S. Experimental study of bridging the peripheral nerve gap with skeletal muscle. Microsurgery, 1986,7(3):183-189

Books:

  1. Zhong SZ, Kong J, Sun B and Williams Yen. Clinical Microsurgical Anatomy. Med Info Publishing Co, Hong Kong, 1991.

Book Chapters:

  1. Li V, Bi X, Szelemej P and Kong J. (2012) Delayed Neuronal Death in Ischemic Stroke: Molecular Pathways. In “Advances in the preclinical study of ischemic stroke", ISBN 978-953-308-71-8, InTech Open Science, Rijeka, Croatia. PP 1-42.
  2. Shi R, Weng J, Szelemej P and Kong J. (2012) Caspase-Independent Stroke Targets. In: Springer Series in Translational Stroke Research: From target selection to clinical trials. Eds: Lapchak PA. and Zhang JH. ISBN 978-1-4419-9529-2. Springer Publishing, New York. PP 60-102.
  3. Weng J and Kong J. (2008) Delayed neuronal death in stroke: molecular pathways. In: John H Zhang. Advancements in Neurological Research, ISBN: 978-81-308-0225-1. Research Signpost, Kerala, India. 1-38.
  4. Xu ZS and Kong J. (2005) Role of mitochondria in motor neuron degeneration in amyotrophic lateral sclerosis. In Amyotrophic Lateral Sclerosis. Mitsumoto H, Przedborski S, Gordon P, Del Bene M, eds. Marcel Dekker Inc., New York, 413-430.
  5. Kong J, Zhong SZ, Hu YM (1996). Target - derived motoneuronal trophic factors. In: Chan SO, Yew D; Development and Regeneration of Nervous Tissues. Hong Kong: Macmillan New Asia Publishing House Limited, 38-46

RESEARCH FUNDING IN LAST 5 YEARS

  1. Kong J (PI) and Li XM (Co-PI). 2014-2016.Protecting delayed neuronal death in ischemic stroke by targeting the BNIP3 pathway. Canadian Institutes of Health Research Canada-China Joint Health Research Initiative program grant. $225,000.
  2. Xing M (PI), Kong J (C0-PI) and Zhong W (Co-PI): 2011-2015. Nanofiberous membrane and stem cells for skin regeneration as a strategic therapy for diabetes skin ulcer. Diabetes Foundation of Manitoba. $45,000.
  3. Li XM (PI) andKong J(Co-PI). 2012-2014 Oligodendrocyte dysfunction in schizophrenia: mechanism and target for treatment. Canadian Institutes of Health Research Regional Partnership Program Operating Grant. $200,000.
  4. Kong J. 2010-2013. Biological function of the VDAC-BNIP3 interaction. Canadian Stroke Network(Centre of Excellence) operating grant. $99,999.
  5. Li XM (PI) andKong J(Co-PI). 2011-2013A mechanistic study of major depressive disorder: the role of oligodendrocytes. Canadian Institutes of Health Research Canada-China Joint Health Research Initiative program grant. $150,000.
  6. Kong J (PI, Project Leader: Li XM), 2010-2013. CIHR Team in Schizophrenia. Are oligodendrocytes the missing piece of the puzzle? A systematic study of the role of oligodendrocytes in schizophrenia from bench-to-bedside,Canadian Institutes of Health Research China-Canada Collaborative Teams in Health Researchgrant, $500,000.
  7. Li XM andKong J. 2010-2012. Therapeutic potentials of desvenlafaxine in depression. Pfizer Canada (IIR Award), $252,473. My portion: 40%
  8. Kong J (PI) and Li X (C0-PI). 2010-2012. Posttranslational oxidative modification of SOD1 as a mechanism of motor neuron death in amyotrophic lateral sclerosis. Canadian Institutes of Health Research Canada-China Joint Health Research Initiative program grant. $150,000.
  9. Li XM (PI) andKong J(Co-PI). 2010 – 2011. Oligodendrocyte dysfunction as a mechanism of schizophrenia and a target for treatment. Canadian Institutes of Health Researchoperating, $100,000.
  10. He J (PI), Kong J (Co-PI) and Li XM (Co-PI). 2010-2011. Therapeutic effect of fluoxetine on memory impairment and brain pathology in a transgenic mouse model of Alzheimer's disease. Health Science Center Foundation operating grant. $35,000.
  11. Kong J. 2008-2010. Rescue of motor neuron death in ALS by targeting the BNIP3 death gene family. Muscular Dystrophy Association of USA Operating grant. $409,081.
  12. Li XM (PI) and Kong J (Co-PI). 2008-2010. Testing the demyelination hypothesis of schizophrenia. Canadian Institutes of Health Research RPP Operating grant. $200,000.
  13. Kong J. 2006-2010. Subcellular analysis centre. Canada Foundation for Innovation Infrastructure maintenance grant. $30,344.
  14. Kong J. 2008-2010. Targeting Cell Death Cascades in the NeuroVascular-Inflammatory Unit.Manitoba Provincial Support for Networks of Centres of Excellence of Canada. $12,120.
  15. Kong J. 2008-2010. Targeting Cell Death Cascades in the NeuroVascular-Inflammatory Unit. Canadian Stroke Network(Centre of Excellence) Team Grant, $66,667.
  16. Kong J. 2007-2009. Amyotrophic lateral sclerosis: Rescue of mutant SOD1-induced motor neuron death by targeting the BNIP3 death gene family. Canadian Institutes of Health Research Regional Partnership Program Operating grant. $200,000.
  17. Kong J. 2007-2009. Protecting delayed neuronal death in stroke by blocking the BNIP3 pathway.Manitoba Health Research Council Operating grant, $111,962.
  18. Kong J. 2004-2007. ‘Atypical neuronal apoptosis in neurodegenerative diseases’ Manitoba Health Research CouncilEstablishment grant, $100,000.
  19. Kong J. 2004-2007. ‘Amyotrophic lateral sclerosis: Role of BNIP3 in mutant SOD1-induced motor neuron death’. Canadian Institutes of Health Research Neuromuscular Research Partnership Operating grant, $211,830.

Studentships / postdoctoral fellowships: