Elena has an MD from the prestigious medical school of Bogomolets National Medical University in Kiev, Ukraine. She completed her residency in Allergy and Immunology at the Academy of Postdoctoral Medical Training in Kiev. She continued her medical research and earned a doctorate in Allergy and Immunology with a subspecialty in Clinical Cardiology. After moving to the United States, Elena completed postdoctoral training at the University of North Carolina, Chapel Hill, which was followed by two years at Harvard Medical School/Massachusetts General Hospital followed by one year at Gray Cancer Institute, London, UK and five years at Duke University Medical Center. She is board-certified in the clinical science of Anti-Aging and Regenerative medicine.
She spent a considerable amount of time developing expertise in the areas of anti-aging and regenerative medicine, woman's health, autoimmune disorders, nutrition, stem cell research, along with neurodegenerative and metabolic disorders. Over the years, she assisted in dealing with a wide range of conditions including hormone imbalances, menopause, surgical menopause, polycystic ovarian syndrome (PCOS), endometriosis, andropause, thyroid disease, adrenal insufficiency, fatigue, insomnia, mild depression, fibromyalgia, incontinence, weight gain, premenstrual tension syndrome, abnormal lipid profile and metabolic syndrome.
Her work has been published in high impact peer-reviewed journals such as the Journal of Cell Biology, Oncogene, Cancer Research, Cell Host and Microbe, Nutrition and Cancer, Pediatric Research and Journal of Immunology and Allergy.
CURRICULUM VITAE / ELENA RUSYN, MD, PhD
Co-Founder of AmpliCell Medical, LLC.
Affiliate of Cell Surgical Network.
EDUCATION/TRAINING/QUALIFICATIONS:
1988-1994 -M.D., Ukrainian State Med. Univ., Kiev, Ukraine; 1994 - 1996, Graduate Research Assistant (Residency training), Department of Clinical Immunology and Allergy, Academy of Postdoctoral Medical Training
Kiev, Ukraine ; 1996- Ph. D., Academy of Postdoctoral Medical Training, Kiev, Ukraine; 2009- ECFMG Certificate, Educational Commission for Foreign Medical Graduates, USA
BOARD CERTIFICATION
Anti-Aging and Regenerative Medicine (ABAARM)
AREAS OF SPECIAL EMPHASIS
Adult Stem Cell Treatment for Autoimmune and Degenerative diseases
Bio-Identical Hormone Replacement
Telomere Science
Lipid Replacement Therapy
Free Radical Research
Mitochondrial Function
Neurobiology
Genomics
Cancer Cell Biology
CURRENT AND PAST MEMBERSHIPS
American Academy of Anti-Aging and Regenerative Medicine
Age Management Medicine Group
Societyfor Neuroscience
Society for Free Radical Research International
Oxygen Society
American Cancer Society
European Society of Parenteral & Enteral Nutrition.
SPECIAL TRAINING
Dr. Rusyn has done special training in Stem Cell Therapy as well as in Telomere Science.
PROFESSIONAL AND RESEARCH EXPERIENCE:
2017 Co-Founder of AmpliCell Medical, LLC
2015- Current Anti-Aging Specialist/Consultant and Independent Contractor in Los Angeles area.
2013 - 2014 Hormone Replacement Specialist, Essential Health & Wellness, PLLC, Cary, NC
2009 - 2013 Hormone Replacement Specialist, All About Aesthetics, PC, Raleigh, NC
2008 - 2009 Research Associate, Department of Molecular Genetics and Microbiology, Duke
University Medical Center, Durham, NC
2004 - 2008 Research Associate, Departments of Pediatrics and Neurobiology, Duke University
Medical Center.
2003 - 2004 Research Scientist (Oncology), Syntherica Corporation, RTP, Durham, NC
2000 - 2003 Postdoctoral Research Fellow, Department of Cancer Cell Biology, Harvard School of Public Health and Department of Radiation Oncology, Harvard University
Medical School/Massachussets General Hospital, MA;
and Gray Laboratory Cancer Research Trust, London, UK.
1997 - 2000 Postdoctoral Research Fellow, Department of Radiation Oncology, University of North Carolina at Chapel Hill.
1994 - 1996 Graduate Research Assistant, Department of Clinical Immunology and Allergology, Academy of Postdoctoral Medical Training, Kiev, Ukraine.
AWARDS AND HONORS
2006 Duke Pediatric Fellows Research Symposium: Best Poster Award
2000 Individual Postdoctoral National Research Service Award, Cancer Cell Biology, NIEHS,
Harvard School of Public Health
1997 Travel Award, DNA Damage and Repair, NATO Advanced Studies Institute
1995 Graduate Student Travel Awards, European Society of Parenteral & Enteral Nutrition
PUBLICATIONS
· El Chebib H, Harati H, Noutsi B, ElMaoued A, Rusyn E, Cotman S, Boustany R. M. Galactosylceramide Corrects Growth and Apoptotic Defects in CLN3-Deficient Cells and Ceramide in homozygous Cln3Δex7/8 Knock-In Mouse Brain and CLN3-deficient cells. Pediatric Research. Submitted.
· Nikitin P, Yan C, Forte E, Bocedi A, Tourigny J, Patel A, Rusyn E, Sandeep D, Kim W, Hu K, Guo J, Tainter D, and Luftig M. An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstain-Barr virus transformation of primary human B cells. Cell Host and Microbe. 2010 Dec 16;8(6):510-22.
· Rusyn E, Mousallem T, Persaud-Sawin D. A, Miller S, Boustany R. M. CLN3p impacts galactosylceramide transport, raft morphology, and lipid content. Pediatric Research, 2008 Jun;63(6):625-31
· Schettino G., Rusyn E. 2002.Low Dose Hypersensitivity and Bystander Responses in Human and Mouse Fibroblasts: A Comparison of Conventional and Focused Soft X-Rays.
· Grana T, Rusyn E, Zhou H, Sartor C.I., and Cox A. D. Ras Mediates Radioresistance through Both Phosphatidylinositol 3-Kinase-dependent and Raf-dependent but Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase-independent Signaling Pathways. Cancer Research 62, 4142– 4150, July 15, 2002
· Hansen M, Rusyn E. V, Hughes P. E, Ginsberg M. H, Cox A. D, Willumsen B. M. R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras. Oncogene, 21 (28):4448-61, 2002
· Rusyn E. V., Reynolds E. R., Shao H., Grana T., Chan T. O., Andres D. A. and Cox A. D. Rit, a
non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK,
JNK, p38 MAPK or PI3K/AKT pathways. Oncogene, 19:4685-4694, 2000.
· Yamashina S, Konno A, Wheeler MD, Rusyn I, Rusyn EV, Cox AD, Thurman RG. Endothelial cells contain a glycine-gated chloride channel. Nutrition and cancer, 40(2):197-204, 2001.
· Yin M., Rusyn I., Schoonhoven R., Harding T. W., Graves L. M., Rusyn E. V., Li X., Cox A. D., Bunzendahl H., Swenberg J. A. and Thurman R. G. Inhibition of chronic rejection of aortic allografts by dietary glycine. Transplantation, 69: 773-780, 2000.
· Keely P. J., Rusyn E. V., Cox A. D., and Parise L. V. R-Ras signals through specific integrin a cytoplasmic domains to promote migration and invasion of breast epithelial cells. J. Cell Biol. 145: 1077-1088, 1999.
· Afonina G. B., Rusin E. V., and Pavlovich A. V. [The role of free radicals in immunoregulation] Dokl. Acad. Sci. Ukraine 16:182-186, 1999. [in Ukrainian].
· Afonina G. B., Yatsenko V. P., Rusin E. V., Belui A. V., and Minchenko Z. N. [To the prognosis of individual radiosensitivity] Dokl. Acad. Sci. Ukraine 16:34-37, 1999. [in Ukrainian].
· Amosova E. N., Afonina G. B., Rusin E. V., and Pavlovich A. V. [The role of free radicals processes in the pathogenesis of ischemic myocardial injury] Ukr. Cardiol. J. 2:69-75, 1999. [in Ukrainian].
· Afonina G. B., Rusin E. V., and Brusgina T. S. [Changes in lymphocyte membranes lipid composition and function in patients with bronchial asthma] J. Immunol. Allergol. (Ukraine). 4:50-55, 1998. [in Ukrainian].
· Afonina G. B., Rusin E. V., and Briuzgina T. S. [The antioxidant resistance of immunocompetent cells]. Klin. Lab. Diagn. 6:35-37, 1998. [in Russian].
· Yatcenko V. P., Afonina G. B., Belui A. V., Rusin E. V., and Brusgina T. S. [The mechanisms of free radical radiation injury to lymphocyte membranes] Dokl. Acad. Sci. Ukraine 10:174-178, 1997. [in Ukrainian].
· Afonina G. B., Girina O. N., Briuzgina T. S., Mostbauer G. V., Rusin E. V., Garkavaia E. G., and Bordonos V. G. [The role of free radical processes in the development of autosensitization in ischemic heart disease]. Lik. Sprava 3-4:52-54, 1995. [in Ukrainian].
*After 1999 the spelling of Rusin was changed to Rusyn (Ukrainian spelling)
NATIONAL AND INTERNATIONAL PRESENTATIONS
Rusyn E, Mousallem T, Persaud-Sawin D-A. CLN3 facilitates GalCer transport to Lipid Rafts. The 11th International Congress on Neuronal Ceroid Lipofuscinoses, Rochester, NY, 2007.
Rusyn E, T. Mousallem, D. Persaud-Sawin, S. Miller and R.M. N. Boustany. Raft morphology and sphingolipids in CLN3-deficient lymphoblasts. Abstract. The 10th International Congress on Neuronal Ceroid Lipofuscinoses, Finland, 2005.
Rusyn E, T. Mousallem, D. Persaud-Sawin, S. Miller and R.M. N. Boustany. The CLN3 protein binds sulfatide and galactosylceramide, 3rd International Charleston Ceramide Conference Charleston, SC, March 2-6, 2005
POSTER ABSTRACTS
E. Rusyn, Mousallem and Boustany R-M. N Galactosylceramide supplementation of JNCL cells restores growth. Pediatric Research Retreat, Duke University Medical Center, Durham, NC, June, 2007
E. Rusyn, Mousallem T, Persaud-Sawin D-A, Miller S, and Boustany R-M. N Altered NCL lipid raft morphology and sphingolipids. Society for neuroscience. Neuroscience 2006, Atlanta, Georgia, October 16, 2006
E. Rusyn, D-A. Persaud-Sawin, T. Mousallem and RM Boustany. Lipid Raft Morphology and Sphingolipids in CLN3-Deficient vs. Normal Lymphoblasts Pediatric Research Retreat, Duke University Medical Center, Durham, NC, June 3, 2006
E. Rusyn, D-A. Persaud-Sawin, T. Mousallem and RM Boustany. Lipid Raft Morphology and Sphingolipids in CLN3-Deficient vs. Normal Lymphoblasts The 3rd International Charleston Ceramide Conference, Charleston, SC, March 2-6, 2005
E. Rusyn, D-A. Persaud-Sawin, and RM Boustany. The CLN3 protein binds to sulfatide and galactosylceramide. 39th South Eastern Regional Lipid Conference,Cashiers, NC, November 3-5, 2004