Curriculum Vitae March 6, 2017
Anna Nolan, MD, MS
e-mail:
Cell: (917) 541-7019Fax: (212) 263-8442
Office:(212)263-7283Lab: (646)501-6783
Website:NYU BiosketchLab Website:Nolan Lab
ORCID iD: 0000-0002-0631-1171
Curriculum Vitae March 6, 2017
Home:25 Waterside Plaza
Apt KK
New York, NY 10010
Office/Lab:462 1st Avenue
New Bellevue 16S16/16N20
New York, NY 10016
Curriculum Vitae March 6, 2017
Education
YearDegreeFieldInstitution
1988 CertificateBronx High School of Science
1992 BA Chemistry Barnard College, Columbia University
1996 MD MedicineSUNY Health Science Center, Brooklyn
2007 MS Clinical Investigation New York University
Postdoctoral Training:
2003-5National Research Service Award, NIH-NIEHS, NYU School of Medicine
Internships and Residencies:
1996-97Intern in Medicine, St. Luke’s-Roosevelt Hospital Center, New York City
1997-99Resident, Internal Medicine, St. Luke’s-Roosevelt Hospital Center, New York City
Clinical and ResearchFellowships:
2000-3Fellow, Pulmonary and Critical Care, NYU School of Medicine
Licensure and Certification
1999New York State License Registration #212947 Active October 2017
1999American Board of Internal Medical (ABIM), #193177 (Re-Certified/Enrolled in MOC)
2000DEA # Active till 10/31/2017
2000NPI #1790848448
2002ABIM, Pulmonary Diseases (Re-Certified/Enrolled in MOC)
2003ABIM, Critical Care Medicine (Re-Certified/Enrolled in MOC)
Academic Appointments
1999-2000 Instructor, St. Luke’s-Roosevelt Hospital Center
2003-2005Instructor, NYU School of Medicine
2005-Assistant Professor of Medicine, New York University, School of Medicine
2009-Assistant Professor of Environmental Medicine, New York University, School of Medicine
2013-Associate, Division of Ethics, Department of Population Health, NYU School of Medicine
2016Recommended for Promotion, Associate Professor of Medicine and Environmental Medicine, New York University, School of Medicine
Hospital Appointments
1999-2000 Instructor, St. Luke’s-Roosevelt Hospital Center, New York
2003-Consultant, Manhattan Veteran’s Hospital, New York
2003-Clinical Assistant, Bellevue Hospital, New York
Other Professional Positions and Major Visiting Appointments
2010-13Pulmonologist, Fire Department of New York, Bureau of Health Services, New York
2013-Medical Officer, Fire Department of New York, Bureau of Health Services, New York
Awards and Honors
1995Dean’s List, Barnard College
2003-5National Research Service Award, NIH-NIEHS, NYU School of Medicine
2004William S. Tillet, Award for Excellence in Research, New York University
2008Excellence in Medical Education, NYU
2010American Thoracic Society(ATS) Abstract Award-Environmental and Occupational Health Assembly
2010Association for Clinical and Translational Science (ACTS) Annual Meeting Trainee Award, Washington, DC
2010LEADS: Leadership, Education and Development for Scientists
2011Scholars Abstract Award from ACTS Washington DC
2012 ATS Abstract Award-Assembly onRespiratory Cell and Molecular Biology(RCMB)
2013ATS Assembly onAllergy, Immunology and Inflammation(AII), Abstract Award- Foundation for Sarcoidosis Research
2014-15Saperstein Scholar, NYU School of Medicine
2016ATS Abstract Award-Environmental and Occupational Health Assembly ‡
2016Burroughs Wellcome Awards for work presented at the ACTS
2016Burroughs Wellcome Awards for work presented at the ACTS
Major Committee Assignments
National and Regional
2016National Ebola Training and Education Center (NETEC)Special Pathogens Research
Network (SPRN)
Data Capture Team
2016Scientific Reviewer: Acute Lung Injury Panel; Peer-Reviewed Medical Research Program for the Department of Defense Congressionally Directed Medical Research Programs, December 2016.
2015On-line Reviewer: Acute Lung Injury I. Peer-Reviewed Medical Research Program for the Department of Defense Congressionally Directed Medical Research Programs-
New York University, School of Medicine
2008-2013 Research Subject’s Safety Officer, General Clinical Research Center/CTSI
2007-2012Alternate/Member, Institutional Animal Care and Use Committee
2010- Member, Institutional Review Board
2016-Member, Scientific Review Committee, NYU SOM
Bellevue Hospital
2009-Member, Bellevue Research Committee
2010-Chair, Bellevue Research Committee
2014-Medical Director of Research, Bellevue Hospital
2016HHC Bellevue Hospital Representative, Research Committee
Memberships, Offices and Committee Assignments in Professional Societies
2001-Member, American Thoracic Society
2001-Fellow, American College of Chest Physicians
2003-Member, Society of Critical Care Medicine
2016-European Respiratory Society
Editorial Positions
Associate Editor
2010-Journal of Inflammation
2013-PLoS ONE
Editorial Boards
2013-PLoS ONE
2013-Austin Journal of Pulmonary and respiratory Medicine
Ad Hoc Reviewer
2005- Chest
2005-Inflammation
2012-PLoS ONE
2012-BMC Pulmonary
2012-American Journal of Respiratory and Critical Care Medicine
2012-International Journal of Tuberculosis and Lung Disease
2013-International Archives of Allergy and Immunology
2013-Environmental Health Perspectives
2013-American Journal of Industrial Medicine
2014-Journal of Epidemiology
2015-Annals of Internal Medicine
2016-Federation of European Biochemical Societies (FEBS) Letters
2016-Pediatric Pharmacology Reviews
2016-Occupational and Environmental Medicine
2017-Annals of the American Thoracic Society
2017-Respirology
2017-Journal of Intensive Care Medicine
Principal Clinical and Hospital Service Responsibilities
1999-2000Attending Physician, St. Luke’s-Roosevelt Hospital Center, New York
2003- Attending Physician, Pulmonary and Critical Care, Bellevue Hospital, New York
2003-Attending Physician, Div. of Pulmonary/Critical Care, Veteran’s Administration Hospital, New York
2010-13Pulmonologist, Fire Department of New York, Bureau of Health Services, New York
2013-Medical Officer, Fire Department of New York, Bureau of Health Services, New York
Major Administrative Responsibilities
2008-2013Research Subjects Safety Officer, General Clinical Research Center/CTSI
2007-2012Alternate/Member, Institutional Animal Care and Use Committee
2009Member, Bellevue Research Committee
2010-Chair, Bellevue Research Committee
2010-Member, NYU IRB
2012-2015Scientific Review Committee NYU-HHC CTSI
2016Scientific Review Committee-Medical Reviewer
Teaching Experience
2001-2003Physical Diagnosis, NYU School of Medicine
2003-Attending Physician, Bellevue Medical ICU and Chest Service
2003-Attending Physician, Veteran’s Administration Hospital, New York
2005-Pulmonary Physiology Seminars, NYU School of Medicine
2009-Lecturer, Molecular Techniques Course, Masters in Clinical Investigation, NYU
2009-Lecturer, Research Retreat, Pulmonary/Critical Care/Sleep Fellowship, NYU
2009-Lecturer, Integrative Seminar, Masters of Clinical Investigation
2010-Mentor, Department of Medicine Summer Fellowship Program, NYU
2016-“Pollution and Lung Health” Passion in Science Program, Salk School of Science
2016-Faculty Editor “Writing for Scientific Publication”focused on CTSI’s MS in Clinical Investigation program and Sackler Institute programs students improve their scientific writing.
Mentoring of High School Students, Medical Students, Residents and Fellows
2005-6Elvio Ardilles, MDPulmonary/Critical Care, California
2005-6S. Ananthanarayanan, MDPhysician, Mount Sinai Medical School
2006-7Nishay Chitkara, MDAssistant Professor, NYU School of Medicine
2007-13Bushra Naveed, MDPost-Doc Fellow, NYU School of Medicine
2007-11Ashley L. Comfort, BSResident, NYU School of Medicine
2007-12Natalia Ferrier, MDPost-Doc Fellow, NYU School of Medicine
2009-10Yingdi Chen, BA Student, NYU School of Medicine
2009-10Shugi Zheng, MDPhysician, Hawaii, USA
2009-Sophia Kwon, DO, MPHPost-Doc Fellow, NYU School of Medicine
2010-12Kusali J. Kasturiarachchi, BAMedical Doctor,University of Queensland, Australia
2011-14Soo Jung Cho, MDInstructor, Cornell School of Medicine
2012-13Bryant BabelStudent, Oceanside High School
2012-13Edward Schenck, MDInstructor, Cornell School of Medicine
2013-14Young Im Lee, MDAttending, Beth Israel Medical Center, NYC
2013-16Erin Caraher, BS, MSMedical Student, New York Medical College
2014-Audrey Lee, BAUndergraduate Student, Brown University
2015-Syed Hissam Haider,MDPost-Doc Fellow, NYU School of Medicine
2015-George CrowleyPre-Doctoral Fellow, University of California, Berkeley
2015-Mohamed Zedan, MD Volunteer, NYU School of Medicine
2015Minah EbrahimVolunteer, Lehigh University
2015-16 Liqun Zhang, MDAssociate Physician-in-Chief, Department of Respiratory Diseases, Beijing Military Region General Hospital of PLA, Visiting Professor
2015 Rachel LamFordham University, BS Candidate
2016 Daniel KimGreat Neck, High School
2016Ramsha SuhailVolunteer, Baruch College, BS Candidate
2016Odai Sinokrot, MDFellow Pulmonary Critical Care, NYU SOM
2016Jonathan BekiszMedical Student, Masters in Clinical Investigation
2016Amanda BienenfeldDental Student, Masters in Clinical Investigation
2016-19Jessica Riggs, MDPulmonary Critical Care Fellow, NYU
2016-19Assad Oskuei, MDPulmonary Critical Care Fellow, NYU
Teaching Awards Received
2008Excellence in Medical Education, Department of Medicine, NYU School of Medicine
Major Research Interests
- Particulate Matter exposure and lung Injury
- Dyslipidemia/Metabolic Syndrome and lung Injury
- Metabolomics of Particulate associated lung disease
- Innate Immunity in Sepsis
- Sarcoidosis and Particulate Matter Exposure
- Research Ethics
- Research Subject Safety
Grants Support
Current
Agency / Title / Type & # / Period / Total Direct Costs/Yr / RoleNIH/NHLBI / RAGE Mediates LPA Induced Pulmonary Inflammation* / R01HL119326-A1 / 9/15-8/20 / $250,000 / PI
CDC/ NIOSH / Roles of Co-pollutants as Factors in WTC First Responder Chronic Lung Ailments / 1U01OH010921 / 8/16-9/20 / $678,000 / Co-I
UNC-CH/ NIH / Metabolomic Biomarkers of World Trade Center Lung Injury in Particulate Matter Exposed Firefighters* / U24DK097193 / 9/16-8/17 / $50,000 / PI
Prior
Agency / Title / Type & # / Period / Direct Costs/Yr / RoleNIH/CTSI / RAGE Mediates LPA Induced Pulmonary Inflammation / CTSI Pilot Project / 1/13-12/15 / $35,000 / PI
Saperstein / LPA and RAGE / NYU Funds / 9/14-12/15 / $35,000 / PI
CDC/NIOSH / Evolution of Risk Factors for Sinusitis inWTC Exposed Firefighters / U01OH010726 / 7/14-6/16 / $969,693 / Co-I
NIH/NHLBI / CD80 and CD86 mediated innate immune response in sepsis. / K23HL08419/S1 / 10/13-9/14 / $159, 138 / PI
NIH/NHLBI / CD80 and CD86 mediated innate immune response in sepsis. / K23HL08419 / PI
Stony-Wold Herbert Fund / CD80 and CD86 mediated innate immune response in sepsis. / Private Foundation / 7/07-5/08 / $25,000 / PI
Empire Clinical Research Investigator Program / Further the understanding of the cellular Expression of CD80/86 and CD28 in human sepsis. * / New York State / 7/06-6/08 / $60,000 / PI
Will Rogers Institute / Study CD80/86 and their ligand CD28 in the innate immune response to murine polymicrobial sepsis. * / Private Foundation / 7/06-6/08 / $60,000 / PI
Center for AIDS Research (CFAR) / The mechanism of HIV-1 mutation during pulmonary tuberculosis* / CFAR / 7/04-6/05 / $35,000 / PI
NIH/NIEHS / Molecular and Cell Biology in Environmental Medicine / T32ES007267 / 7/03-9/05 / $298,703 / I
Pending
Agency / TITLE / Type & # / Period / DirectCosts/ Yr / Role / Comments
CDC/
NIOSH / Metabolomics of World Trade Center-Lung Injury: Biomarker Validation, Longitudinal Assessment and Dietary Intervention. / U01OH011300 / 07/17- 06/21 / $600,000 / PI / Submitted
Dec 2016
NHLBI / Integrative OMICS: Biomarkers of Particulate Matter Induced Lung Injury. / R01ES028706 / 09/17-08/22 / $250,000 / PI / Submitting
Feb 2017
CDC/
NIOSH / Interactive effects of WTC dust and cigarette smoke in First Responders / U01 / 07/16-06/21 / 400,000 / Co-I / Submitted
Dec 2016
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- Loupasakis K; Berman J; Jaber N; Zeig-Owens R; Webber MP; Glaser MS; Moir W; Qayyum B; Weiden MD; Nolan A; Aldrich TK; Kelly KJ; Prezant DJ. Refractory sarcoid arthritis in world trade center-exposed New York city firefighters: a case series. J Clin Rheumatol. 2015 Jan; 21(1):19-23.
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- Glaser MS; Webber MP; Zeig-Owens R; Weakley J; Liu X; Ye F; Cohen HW; Aldrich TK; Kelly KJ; Nolan A; Weiden MD; Prezant DJ; Hall CB. Estimating the Time Interval between World Trade Center Exposure and Incident Diagnoses of Obstructive Airway Disease. American Journal of Epidemiology. June 2014:555-563
- Nolan A; Kwon S; Cho SJ; Naveed B; Comfort AL; Prezant DJ; Rom WN; Weiden MD. MMP-2 and TIMP-1 Predict Healing of WTC-Lung Injury in New York City Firefighters. Respiratory research. 2014 Jan;15(1):5-5
- Cho SJ; Echevarria GC; Lee YI; Kwon S; Park KY; Tsukiji J; Rom WN; Prezant DJ; Nolan A; Weiden MD. YKL-40 is a Protective Biomarker for Fatty Liver in World Trade Center Particulate Matter-Exposed Firefighters.Journal of molecular biomarkers & diagnosis. 2014:5.
- Kwon S; Weiden MD; Echevarria GC; Comfort AL; Naveed B; Prezant DJ; Rom WN;Nolan A. Early Elevation of Serum MMP-3 and MMP-12 Predicts Protection from World Trade Center-Lung Injury in New York City Firefighters: A Nested Case-Control Study. PLoSONE2013. 8(10): e76099.
- Cho SJ;Echevarria GC; Rom WN; Prezant DJ; Nolan A; Weiden MD. One Airway: Biomarkers of Protection from Upper and Lower Airway Injury after World Trade Center Exposure.Respir Med. 2014 Jan;108(1):162-70
- Niles JK; Webber MP; Cohen HW; Hall CB; Zeig-Owen R; Ye F; Glaser MS; Weakley J; Weiden MD; Aldrich TK; Nolan A; Glass L; Kelly KJ; Prezant DJ. The Respiratory Pyramid: From Symptoms to Disease in World Trade Center Exposed Firefighters. American journal of Industrial medicine. 2013 Jun;268-271
- Nolan A; Fajardo E; Huie M;Condos R;Dawson R; Dheda K; Bateman E;Rom WN; Weiden MD. Increased production of IL-4 and IL-12p40 from bronchoalveolar lavage cells are biomarkers of Mycobacterium tuberculosis in the sputum. 2013; 8(3):e59461-e59461. PLoS ONE.
- Nolan A; Rany Condos; Huie ML; Dawson R; Dheda K; BatemanE; RomWN; Weiden MD. Exaggerated release of IP-10 and IL-6 from bronchoalveolar lavage cells are biomarkers of protection from pulmonary cavities during tuberculosis. International journal of tuberculosis & lung disease. 2013 Jul;17(7):922-927
- Adamson R; Lee YI; Sutin K; Berger KI; Nolan A. Acute Respiratory Failure Secondary to Achalasia. Annals of the American Thoracic Society. 2013 Jun;10(3):268-271
- Cho SJ; Nolan A; Echevarria GC; Kwon S; Naveed B; Schenck, Edward; Tsukiji, Jun; Prezant, David J; Rom, William N; Weiden, Michael D. Chitotriosidase is a Biomarker for the Resistance to World Trade Center Lung Injury in New York City Firefighters. June 2013:1134-1142, Journal of Clinical Immunology
- Weiden MD; Naveed B; Kwon S; Cho SJ; Comfort AL; Prezant DJ; Rom WN; Nolan A. Cardiovascular Disease Biomarkers Predict Susceptibility or Resistance to Lung Injury in World Trade Center Dust Exposed Firefighters. Eur Respir J 2013; 41: 1023–1030
Editorial: Antao VC. The world trade center disaster: A tragic source of medical advancement. Eur Respir J. 2013; 41: 999-1001
- Aldrich TK; Fen Y; Hall CB; Webber MP; Cohen HW; Dinkels M; Cosenza K; Weiden MD; Nolan A; Christodoulou V; Kelly KJ; Prezant DJ. Longitudinal Pulmonary Function in Newly-hired Non-WTC-exposed FDNY Firefighters: the First 5 Years. 2012 Sep;:791-797, Chest.
- Weiden MD; Naveed B; Kwon S; Segal LN; Cho SJ; Tsukiji J; Kulkarni R; Comfort AL; Kasturiarachchi KJ; Prophete C; Cohen MD; Chen LC; Rom WN; Prezant DJ; Nolan A. Comparison of WTC Dust Size on Macrophage Inflammatory Cytokine Release In vivo and In vitro. 2012 July; 7(7): e40016, PLoSONE.
- Naveed B;Weiden MD;Kwon S; Gracely EJ; Comfort AL; Ferrier N; Kasturiarachchi KJ; Cohen HW; Aldrich TK; Rom WN; Kelly K; Prezant DJ; Nolan A. Metabolic Syndrome Biomarkers Predict Lung Function Impairment: A Nested Case-Control Study. E-Published on November 17, 2011 as doi: 10.1164/rccm.201109-1672OC. 2012 Feb; 185(4):392-399. Am. J. Respir. Crit. Care Med.
Editorial: Holguin F. The metabolic syndrome as a risk factor for lung function decline. Am. J Respir. Crit. Care Med. 2012; 185:352-353
- Nolan A; Naveed B; Comfort AL; Ferrier N; Hall CB; Kwon S; Kasturiarachchi KJ; Cohen HW; Zeig-Owens R; Glaser MS; Webber MP; Aldrich TK; Rom WN; Kelly K; Prezant DJ; Weiden MD. Inflammatory Biomarkers Predict Airflow Obstruction After Exposure to World Trade Center Dust Epub 2011 Oct 13 2012 August; 142(2):412-418, Chest.
Editorial: Balmes JR. Can we predict who will develop chronic sequelae of acute inhalational injury? Chest. 2012;142:278-279
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- Segal LN; Methe BA; Nolan A; Hoshino Y; Rom W N; Dawson R; Bateman E; Weiden M D. HIV-1 and Bacterial Pneumonia in the Era of Antiretroviral Therapy. 2011 Jun;8(3): 282-7, Proceedings of the American Thoracic Society.
- Kobayashi H; Nolan A; Naveed B; Hoshino Y; Segal L N; Fujita Y; Rom W N; Weiden M D.Neutrophils Activate Alveolar Macrophages by Producing Caspase-6-Mediated Cleavage of IL-1 Receptor-Associated Kinase-M 2011 Jan 1;186(1):403-10 Journal of Immunology.
- Weiden MD; Ferrier N; Nolan A; Rom WN; Comfort A; Gustave J; Zeig-Owens R; Zheng S; Goldring RM; Berger K I; Cosenza K; Lee R; Webber M P; Kelly Kerry J; Aldrich T K; Prezant D J. Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust. 2010 Mar; 137 (3):566-74 Chest.
- Nolan A; Kobayashi H; Naveed B; Kelly A; Hoshino Y; Hoshino S; Karulf M R; Rom WN; Weiden MD; Gold JA. Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis. 2009 Aug 12; 4(8):e6600 PLoS ONE.
- Raju B; Hoshino Y; Belitskaya-Levy I; Dawson R; Ress S; Gold J A; Condos Rany; Pine Richard; Brown Stuart; Nolan A; Rom WN; Weiden M D.Gene expression profiles of bronchoalveolar cells in pulmonary TB 2008 Jan; 88(1):39-51. Tuberculosis. id: J0130152.
- Nolan A; Weiden MD; Kelly A; Hoshino Y; Hoshino S; Mehta N; Gold JA. CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis. 2008 Feb 1; 177(3): 301-8 Am J Respir Crit Care Med. id: J0137887.
- Gold JA; Hoshino Y; Jones MB; Hoshino S; Nolan A; Weiden MD. Exogenous interferon-alpha and interferon-gamma increase lethality of murine inhalational anthrax
2007 Aug 15;2(1):e736 PLoS ONE. - Gold JA; Rimal B; Nolan A; Nelson Lewis S. A strategy of escalating doses of benzodiazepines and phenobarbital administration reduces the need for mechanical ventilation in delirium tremens. 2007 Mar; 35(3):724-30 Critical Care Medicine.
- Nolan A; Weiden MD; Thurston G; Gold JA. Vascular endothelial growth factor blockade reduces plasma cytokines in a murine model of polymicrobial sepsis (2004) Oct;28 (5):271-8 Inflammation.
- Nolan A; Weiden MD; Hoshino Y; Gold JA. CD40 but not CD154 knockout mice have reduced inflammatory response in polymicrobial sepsis: a potential role for Escherichia coli heat shock protein 70 in CD40-mediated inflammation in vivo 2004 Dec; 22(6):538-42, Shock.
- Gold JA; Hoshino Y; Hoshino S; Jones MB; Nolan A; Weiden MD.Exogenous gamma and alpha/beta interferon rescues human macrophages from cell death induced by Bacillus anthracis. 2004 Mar; 72(3):1291-7, Infection & Immunity.
- Gold Jeffrey A; Parsey M; Hoshino Y; Hoshino S; Nolan A; Yee H; Tse DB; Weiden MD. CD40 contributes to lethality in acute sepsis: in vivo role for CD40 in innate immunity. 2003 Jun;71(6):3521-8, Infection & Immunity.
- Pagnotta M; Nolan A; Kim L. A Simple Modification of a Domestic Microwave Ovenfor Improved Temperature Control. 1992 July; 69 (7): 599-600 Journal of Chemical Education.
ABSTRACTS UNDER REVIEW
- G Crowley; S Kwon, SH Haider, L Zhang, R Lam, D Kim, M Liu; DJ Prezant; A Nolan. Metabolite and Biomarker Predictors of WTC-Lung Injury: an Integrated Multiplatform Pilot Analysis. Military Health System Research Symposium, August 2017.
- S.H. Haider, G. Crowley, R. Lam, S. Kwon, L.C. Chen, A.M. Schmidt, D.J. Prezant, A. Nolan. Loss of RAGE Mitigates Persistant Airway Hyperreactivity after Intense Particulate Matter Exposure. Military Health System Research Symposium, August 2017
ABSTRACTS (87 Total)