Contribution of P.C. Endler to the WHO-Report on Homeopathy Research, (to be published by the WHO in 2004)

Section Basic Research on Zoological Models

Thyroxin was administered in succussed high dilution (30X, 10-30) to amphibian larves at the end of their metamorphosis from tadpoles to frogs. In the observed stage, the thyroxin level of the larves is comparatively high, and molecular thyroxin is well known to speed up metamorphosis. In contrast, under the influence of thyroxin 30X, metamorphosis slowed down (Endler et al 1994a,b, 1997, 1998a, Zausner et al 2002). This was found in independent studies in 5 laboratories.

The slowing down effect of succussed thyroxin dilution was even more marked, when the animals were previously hyperstimulated (intoxicated) with molecular doses of thyroxin (Zausner et al 2002, Endler et al 2003). Analogous observations were made when information of the succussed thyroxin dilution was transmitted through an electronic device, including digitized information storage (Senekowitsch et al. 1995, Endler et al 1995, 1997).

Section Basic Research on Botanical Models

As a repetition of a plant study from the beginning of the 20th century, a succussed high dilution of silver nitrate (24X) was administered to wheat seedlings. In consecutive series of experiments, wheat seedling development was highly significantly enhanced by the test dilution, compared to analogously prepared control dilution (Pongratz et al. 1994, 1998)

References

Endler P.C., Pongratz W., Kastberger G., Wiegant F.A.C., Haidvogel M. Climbing activity in frogs and the effect of highly diluted succussed thyroxine. Br. Hom. J. 1991;80:194-200

Endler P.C., Pongratz W., Kastberger G., Wiegant F.A.C., Schulte J. The effect of highly diluted agitated thyroxine on the climbing activity of frogs. Vet. Hum. Tox. 1994a;36:56-59

Endler P.C., Schulte J. (eds.). Ultra High Dilution: Physiology and Physics. Kluwer Academic Publishers, Dordrecht 1994b

Endler P.C., Pongratz W., van Wijk R., Waltl K., Hilgers H., Brandmaier R. Transmission of hormone information by nonmolecular means. FASEB J. 1994c;8,4:A400 (Abs.)

Endler P.C., Pongratz W., van Wijk R., Wiegant F.A.C., Waltl K., Gehrer M., Hilgers H. A zoological example on ultra high dilution research. In: Endler P.C., Schulte J. (Hrsg.). Ultra High Dilution: Physiology and Physics. Kluwer Academic Publishers, Dordrecht 1994d

Pongratz W., Endler P.C. Reappraisal of a classical botanical experiment on ultra high dilution research. Energetic coupling in a wheat model. In: Endler P.C., Schulte J. (eds.). Ultra High Dilution: Physiology and Physics. Kluwer Academic Publishers, Dordrecht 1994

Endler P.C., Pongratz W., Smith C.W., Schulte J. Non-molecular information transfer from thyroxine to frogs with regard to ´homoeopathic´ toxicology. Vet. Hum. Tox. 1995;37(3):259-260

Endler P.C., Schulte J. (Hrsg.). Homöopathie - Bioresonanztherapie. Physiologische und physikalische Voraussetzungen - Grundlagenforschung. Verlag Maudrich, Wien-München-Bern 1996

Endler P.C., Pongratz W., Smith C.W., Schulte J., Senekowitsch F., Citro M, Non-molecular information transfer from thyroxine to frogs.In: Bastide M. (ed.), Signals and Images, Kluwer Academic Publishers Dordrecht, 1997; pp 149 - 159

Endler P.C., Heckmann C., Lauppert E., Pongratz W., Alex J., Dieterle D., Lukitsch C., Vinattieri C., Smith C.W., Senekowitsch F., Möller H., Schulte J. The metamorphosis of amphibians and information of thyroxine. In: Schulte J, Endler P.C. (Hrsg.). Fundamental Research in Ultra High Dilution and Homoeopathy. Kluwer Academic Publishers, Dordrecht, 1998a

Endler P.C. Fundamental research on high dilution effects. A classification of non-clinical research topics. In: Schulte J, Endler P.C. (Hrsg.). Fundamental Research in Ultra High Dilution and Homoeopathy. Kluwer Academic Publishers, Dordrecht, 1998b.

Schulte J, Endler P.C. (Hrsg.). Fundamental Research in Ultra High Dilution and Homoeopathy. Kluwer Academic Publishers, Dordrecht, 1998c

Pongratz W., Nograsek A., Endler C. Highly diluted agitated silver nitrate and wheat seedling development. In: Schulte J, Endler P.C. (Hrsg.). Fundamental Research in Ultra High Dilution and Homoeopathy. Kluwer Academic Publishers, Dordrecht, 1998

Pongratz W., Nograsek A., Endler C. Highly diluted agitated silver nitrate and wheat seedling development. In: Schulte J, Endler P.C. (Hrsg.). Fundamental Research in Ultra High Dilution and Homoeopathy. Kluwer Academic Publishers, Dordrecht, 1998. Also in: Taddei-Ferretti C., Marotta P. (Hrsg.) High Dilution Effects on Cells and Integrated Systems. World Scientific Publishers, Singapore - London, 1998

Lauppert E., Endler P.C. Enhanced inversion effect of thyroxine 10-13 by agitation. Curative effect following hyperstimulation in frogs. In: Taddei-Ferretti C., Marotta P. (Hrsg.) High Dilution Effects on Cells and Integrated Systems. World Scientific Publishers, Singapore - London, 1998

Endler P.C. Expedition Homöopathieforschung. Ein altes Heilsystem wird plausibel. Maudrich Verlag, Wien, 1998d

Zausner C, Lassnig H, Endler PC, Scherer W, Haidvogl M, Frass M, Kasteberger G, Lüdtke R: Die Wirkung von "homöopathisch" zubereitetem Thyroxin auf die Metamorphose von Hochlandamphibien - Ergebnisse einer multizentrischen Kontrollstudie. Perfusion 2002; 17: 268-276

Endler P.C.: Homeopathy - An Expedition Report. An old healing system gains plausibility. , 2003

Endler P.C., Lüdtke R., Heckmann C., Zausner C., Lassnig H., Scherer-Pongratz W., Haidvogl M., Frass M.: Pretreatment with thyroxin (10-8 parts by weight) enhances a "curative" effect of homeopathically prepared thyroxin (10-13) on lowland frogs. Research on Complementary Medicine / Forschende Komplementärmedizin, 2003; 10: 137-142