***** Conserved Regions - Zebrafish Mar. 2006 chr7 (Human Mar. 2006 chr7) *****

49526334 (155297577) to 49526633 (155297278) = 300bp at 74.7% exon

49528383 (155294212) to 49528475 (155294121) = 93bp at 79.6% intron

49529943 (155292012) to 49530204 (155291751) = 262bp at 77.9% exon

49531626 (155289179) to 49531808 (155288999) = 187bp at 69.5% exon

49532789 (155287807) to 49532899 (155287688) = 121bp at 76.9% UTR

49533106 (155287387) to 49533229 (155287281) = 124bp at 70.2% UTR

Total 1087bp at 74.7%

chr7:49,528,206-49,528,595 è full text ... need more nucleic acids

chr7:49,527,642-49,529,324 è full text

>danRer4_dna range=chr7:49527642-49529324 5'pad=0 3'pad=0 strand=+ repeatMasking=none

CCCTTTGCCAATGCTAAGGAAGAATAACATGCAGCTTACTAAGTGCATCG

AAAATATGTTTGCAGTGCAAATTAGCCTCTATTGAAGTGTTTCCGTGTAA

TTTACAAAGTGATTATCCCGAGCATAATTTTTATTAGGCTGTTTTGAACG

TGCCTCTGTTAAATAGCTTTTAGGTTCAAAGTCTAAGTCATGACCGGTTA

TAGCAAGGTTTGCTGAAGCATTGCGAATAATGTCCGCCAAAGTCAATTTA

CACGCGCCGCGCAGGTGCATTATAAAGTTTCCCTTTTACCGGTCCTTAAA

AAAGATGAAACCCGTGTCTGGTGTGGTTTTCTCAGATGTATATCAAGCTC

TACTTAAGGTGAATGTGATTATAAGTGTGCAGTGACCCGCGGGCACACAC

GCTGCTATAAGCTACCCTTGCAATCTAGTAACATCAAATGAACGTCTCAG

TCTTTCAAAGGGAGTTAACGAGGTGTCCTGTTGACAAATGTTTTGGAGAA

GCGCATCCGAGTGTAAGACAGGGTTTGTTGGTTGAACACGCTGTGCGGTG

AATTGGACTTAACGGTGAAGCTCGCGAAATTAGGCGCAACTGCGAGGGTA

TCCAGGAGGCTGTTTGCTCTGACAGGTAGCTGATAAGTGTTTCCTCTAAA

ACAGTTCATTTTGGGGGGAGATTAGTTGCTGACTGTGACTAGGCGGCTTG

TTGAACAAACCTCGTGTGGAGCACAAAGCGGCG[GCACAGGGGGTTCCCGC

TGCGCTTCATGGTGGCTGAACAGAATTTGGCTTGATTTGCGGCACACGAC

TCAATGAATTAATAAAGAGTTCAGGCT]TCACGGCTCATCAATCCCCGGTA

GTTTTGCTTAGGATGTGCTAGGTTGCATCTTTATGTCGCTTGCTTGTGGT

TTACTCTATCAATCAACAGCCACAAGTGTTGTAGAGCTAAAAGGCAGCAA

TTTAAAATATAGTAGTTAGGGGGTCTGTTTTATTTACTTTTGATTAAAGT

ACCATTTTGCTACATTCCATTCAGTGTACAGATATTCCAAAAAGGCATCA

TCCAGAGGATGCATCTGTGAAGTTTTTGCAATTTATTTCATTAGACTATA

TCGTTTGTATAATAGACTCTAGAAACACAATGAAGTGAACTGAACAGTTT

CATACATTCAGATATAATTCAGTGTAGTTTATAATTGACTAAACATTATT

TTTCTGATATACAATAAAGTGCAATTCAGCTTAGTAAAGTGCATATGGTC

TTCACTGCTGACATGAAAATTAGAGGGTCAAGCAGATCAGTAGGAAGTGG

GGCGATAGTCTGCTGGAGAAATTTATGTGGATGTTAGAGGCTAAGGATGT

GTGTGTGTGTGTGTGTGTATAAGGGGGGAGAGTCAGAGAAAGCGAGCAAG

TGAGTCAAAGCTAGGAGGGTATGTGTGTGAATTATTACAGGTATTAATTT

GGCTTAGTGTCACAATTTGCCAGCATATTTTGAATAGATTTTATATAACC

TCTGAAAGACCGTCAGTTAAGCAATCACATCACGTCCCTTGAGCAAACCT

GTGCTGCAAGAATAATGAGTAGTTGCTTCTCCTCTTGGACGCAGTGAAAG

AGTCTTTTGTGGTGTTTTATTTGACATATTGGTTAAGTGTTGGGAAGAGT

TGTCCTGGTGAAGGCCAAGCATCTCAAAGCAAG

chr7:49,528,375-49,528,468 è just CNS


>danRer4_dna range=chr7:49528375-49528468 5'pad=0 3'pad=0 strand=+ repeatMasking=none

GCACAGGGGGTTCCCGCTGCGCTTCATGGTGGCTGAACAGAATTTGGCTT

GATTTGCGGCACACGACTCAATGAATTAATAAAGAGTTCAGGCT

Primer 3 Design:

Primer3 Output

No mispriming library specified

Using 1-based sequence positions

OLIGO start len tm gc% any 3' seq

LEFT PRIMER 701 20 60.13 45.00 4.00 0.00 TTGAACAAACCTCGTGTGGA

RIGHT PRIMER 899 20 59.87 45.00 2.00 0.00 CCACAAGCAAGCGACATAAA

SEQUENCE SIZE: 1683

INCLUDED REGION SIZE: 1683

PRODUCT SIZE: 199, PAIR ANY COMPL: 5.00, PAIR 3' COMPL: 1.00

TARGETS (start, len)*: 734,94

1 CCCTTTGCCAATGCTAAGGAAGAATAACATGCAGCTTACTAAGTGCATCGAAAATATGTT

61 TGCAGTGCAAATTAGCCTCTATTGAAGTGTTTCCGTGTAATTTACAAAGTGATTATCCCG

121 AGCATAATTTTTATTAGGCTGTTTTGAACGTGCCTCTGTTAAATAGCTTTTAGGTTCAAA

181 GTCTAAGTCATGACCGGTTATAGCAAGGTTTGCTGAAGCATTGCGAATAATGTCCGCCAA

241 AGTCAATTTACACGCGCCGCGCAGGTGCATTATAAAGTTTCCCTTTTACCGGTCCTTAAA

301 AAAGATGAAACCCGTGTCTGGTGTGGTTTTCTCAGATGTATATCAAGCTCTACTTAAGGT

361 GAATGTGATTATAAGTGTGCAGTGACCCGCGGGCACACACGCTGCTATAAGCTACCCTTG

421 CAATCTAGTAACATCAAATGAACGTCTCAGTCTTTCAAAGGGAGTTAACGAGGTGTCCTG

481 TTGACAAATGTTTTGGAGAAGCGCATCCGAGTGTAAGACAGGGTTTGTTGGTTGAACACG

541 CTGTGCGGTGAATTGGACTTAACGGTGAAGCTCGCGAAATTAGGCGCAACTGCGAGGGTA

601 TCCAGGAGGCTGTTTGCTCTGACAGGTAGCTGATAAGTGTTTCCTCTAAAACAGTTCATT

661 TTGGGGGGAGATTAGTTGCTGACTGTGACTAGGCGGCTTGTTGAACAAACCTCGTGTGGA

>

721 GCACAAAGCGGCGGCACAGGGGGTTCCCGCTGCGCTTCATGGTGGCTGAACAGAATTTGG

***********************************************

781 CTTGATTTGCGGCACACGACTCAATGAATTAATAAAGAGTTCAGGCTTCACGGCTCATCA

***********************************************

841 ATCCCCGGTAGTTTTGCTTAGGATGTGCTAGGTTGCATCTTTATGTCGCTTGCTTGTGGT

<

901 TTACTCTATCAATCAACAGCCACAAGTGTTGTAGAGCTAAAAGGCAGCAATTTAAAATAT

961 AGTAGTTAGGGGGTCTGTTTTATTTACTTTTGATTAAAGTACCATTTTGCTACATTCCAT

1021 TCAGTGTACAGATATTCCAAAAAGGCATCATCCAGAGGATGCATCTGTGAAGTTTTTGCA

1081 ATTTATTTCATTAGACTATATCGTTTGTATAATAGACTCTAGAAACACAATGAAGTGAAC

1141 TGAACAGTTTCATACATTCAGATATAATTCAGTGTAGTTTATAATTGACTAAACATTATT

1201 TTTCTGATATACAATAAAGTGCAATTCAGCTTAGTAAAGTGCATATGGTCTTCACTGCTG

1261 ACATGAAAATTAGAGGGTCAAGCAGATCAGTAGGAAGTGGGGCGATAGTCTGCTGGAGAA

1321 ATTTATGTGGATGTTAGAGGCTAAGGATGTGTGTGTGTGTGTGTGTGTATAAGGGGGGAG

1381 AGTCAGAGAAAGCGAGCAAGTGAGTCAAAGCTAGGAGGGTATGTGTGTGAATTATTACAG

1441 GTATTAATTTGGCTTAGTGTCACAATTTGCCAGCATATTTTGAATAGATTTTATATAACC

1501 TCTGAAAGACCGTCAGTTAAGCAATCACATCACGTCCCTTGAGCAAACCTGTGCTGCAAG

1561 AATAATGAGTAGTTGCTTCTCCTCTTGGACGCAGTGAAAGAGTCTTTTGTGGTGTTTTAT

1621 TTGACATATTGGTTAAGTGTTGGGAAGAGTTGTCCTGGTGAAGGCCAAGCATCTCAAAGC

1681 AAG

KEYS (in order of precedence):

****** target

> left primer

< right primer

ADDITIONAL OLIGOS

start len tm gc% any 3' seq

1 LEFT PRIMER 701 20 60.13 45.00 4.00 0.00 TTGAACAAACCTCGTGTGGA

RIGHT PRIMER 859 20 59.84 45.00 4.00 3.00 AAGCAAAACTACCGGGGATT

PRODUCT SIZE: 159, PAIR ANY COMPL: 4.00, PAIR 3' COMPL: 3.00

2 LEFT PRIMER 702 20 59.72 50.00 3.00 1.00 TGAACAAACCTCGTGTGGAG

RIGHT PRIMER 899 20 59.87 45.00 2.00 0.00 CCACAAGCAAGCGACATAAA

PRODUCT SIZE: 198, PAIR ANY COMPL: 5.00, PAIR 3' COMPL: 0.00

3 LEFT PRIMER 702 20 59.72 50.00 3.00 1.00 TGAACAAACCTCGTGTGGAG

RIGHT PRIMER 859 20 59.84 45.00 4.00 3.00 AAGCAAAACTACCGGGGATT

PRODUCT SIZE: 158, PAIR ANY COMPL: 4.00, PAIR 3' COMPL: 2.00

4 LEFT PRIMER 701 20 60.13 45.00 4.00 0.00 TTGAACAAACCTCGTGTGGA

RIGHT PRIMER 903 20 60.44 45.00 2.00 0.00 TAAACCACAAGCAAGCGACA

PRODUCT SIZE: 203, PAIR ANY COMPL: 5.00, PAIR 3' COMPL: 2.00

Statistics

con too in in no tm tm high high high

sid many tar excl bad GC too too any 3' poly end

ered Ns get reg GC% clamp low high compl compl X stab ok

Left 6154 0 0 0 8 0 2453 1938 1 7 44 92 1611

Right 7779 0 0 0 495 0 3948 1261 0 1 22 66 1986

Pair Stats:

considered 10178, unacceptable product size 10167, ok 11

primer3 release 1.1.4

(primer3_results.cgi release 0.4.0)