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*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : BQ4550000
CHEMICAL NAME : Ammonium,
ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(o-sulfo
phenyl)benzylidene)-
2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-,
hydroxide, inner salt, diammonium salt
CAS REGISTRY NUMBER : 2650-18-2
LAST UPDATED : 199710
DATA ITEMS CITED : 14
MOLECULAR FORMULA : C37-H36-N2-O9-S3.2H3-N
MOLECULAR WEIGHT : 783.01
WISWESSER LINE NOTATION : L6Y DYJ AUYR BSWQ&R DN2&1R CSWQ& DUK2&1R CSWQ &Q &ZH
2
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Human
SYNONYMS/TRADE NAMES :
* Acid Blue 9
* Acilan Turquoise Blue AE
* A.F. Blue No. 1
* Aizen Brilliant Blue FCF
* Alphazurine
* Alphazurine FG
* Alphazurine FGND
* Alphazurine (indicator)
* Amacid Blue FG Conc
* Bleu Brilliant FCF
* 11388 Blue
* Brilliant Blue
* Bucacid Azure Blue
* Calcocid Blue EG
* Calcocid Blue 2G
* C.I. 42090
* C.I. Acid Blue 9
* C.I. Acid Blue 9, diammonium salt
* C.I. Food Blue 2
* D and C Blue No. 4
* Disulphine Lake Blue EG
* Duasyn Acid Blue AE
* Edicol Supra Blue E6
* Erioglaucine
* Erioglaucine A
* Erioglaucine E
* Eriosky Blue
* Fenazo Blue XR
* Food Blue 1
* Hidacid Azure Blue
* H.K. Formula No. K. 7117
* Kiton Blue AR
* Kiton Pure Blue L
* Maple Brilliant Blue FCF
* Neptune Blue BRA
* Orient Water Blue 9
* Patent Blue AE
* Patent Blue 2Y
* Peacock Blue X-1756
* Triantine Light Brown 3RN
* Water Blue 9
* Xylene Blue VSG
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Human
DOSE/DURATION : 33 ug/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
Academic Press, Inc., 1969 Volume(issue)/page/year: -,87,1969
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10 gm/kg/77W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
8,29,1966
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 3333 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,223,1987
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 200 umol/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 7,101,1985
TYPE OF TEST : Unscheduled DNA synthesis
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 500 mg/kg
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 7,101,1985
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 571 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,223,1987
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Fibroblast
DOSE/DURATION : 5 gm/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,623,1984
*** REVIEWS ***
TOXICOLOGY REVIEW
ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For
publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2196
No. of Facilities: 811 (estimated)
No. of Industries: 20
No. of Occupations: 27
No. of Employees: 17059 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M2196
No. of Facilities: 2902 (estimated)
No. of Industries: 26
No. of Occupations: 41
No. of Employees: 96076 (estimated)
No. of Female Employees: 62671 (estimated)
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Negative: B subtilis rec assay; Histidine
reversion-Ames test
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***