Brian J. Bennett, Phdrevised 4/23/15

Brian J. Bennett, Phdrevised 4/23/15

Brian J. Bennett, PhDRevised 4/23/15

Curriculum Vitae

1) Personal Information:

Home:Mailing address:

135 Fairview LanePO Box 2267

Davidson, NC 28036Davidson, NC 28036

Office:

500 Laureate Way, Suite 2303

Kannapolis NC 28081

Tel: 704-250-5044

2) Education

Postdoctoral Fellow, University of California Los Angeles, 2006-2011, Genetics

PhD, University of Washington, 2006, Nutritional Sciences

Certificate in Public Health Genetics, University of Washington, 2004

MS, University of New Hampshire, 1997, Animal and Nutritional Sciences

BS, Ithaca College, 1995, Exercise Science

3) Professional Experience – Employment History

University of North Carolina at Chapel Hill (UNC-CH) Department of Nutrition

Assistant Professor (Joint), 2013-present

University of North Carolina at Chapel Hill (UNC-CH) Department of Genetics

Assistant Professor (Primary), 2011-present

Pfizer Animal Health, Business Systems Analyst, 1998-2001

4) Honors

  • Junior Faculty Development Award University of North Carolina, Chapel Hill, December 2013
  • Early Career Investigator Travel Stipend Award, Kern Aspen Lipid Conference, July 2012
  • Early Career Investigator Travel Stipend Award, Kern Aspen Lipid Conference, August 2011
  • George J. Popjak Fellowship in Research Related to Atherosclerosis, UCLA School of Medicine, December 2010
  • Early Career Investigator Travel Stipend Award, Kern Aspen Lipid Conference, 2009
  • Department of Medicine Research Day poster competition, Third Place 1000 honorarium, 2008
  • Scholarship to attend Annual Short Course on Systems Genetics, The Jackson Laboratory, Bar Harbor Maine, 2008
  • Scholarship to attend 48th Annual Short Course on Medical and Experimental Mammalian Genetics, The Jackson Laboratory, Bar Harbor Maine, 2007
  • Edith Molton Scholarship, 2004
  • Student Representative for the American Association of Nutrition Sciences’ 2003

Graduate Nutrition Education Committee

  • Leadership Award, Pfizer Animal Health January, 1999

5) Bibliography and products of scholarship

Refereed Papers/Articles

Original Research

  1. Identification of aortic arch-specific quantitative trait loci for atherosclerosis by an intercross of DBA/2J and 129S6 apolipoprotein E-deficient mice. Kayashima Y, Makhanova NA, Matsuki K, Tomita H, Bennett BJ, Maeda N. PLoS One. 2015 Feb 17;10(2):e0117478.
  2. Gregory J, Buffa JA, Org E, Wang E, Levison BS, Zhu W, Wagner MA, Bennett BJ, Li L, DiDonato JA, Lusis AJ, Hazen SL Transmission of atherosclerosis susceptibility with gut microbial transplantation. J Biol Chem. 2015 Feb 27;290(9):5647-60
  1. Shih D; Zeneng Wang; Richard Lee; Meng, Yonghong; Che, Nam; Charugundla, S; Qi H; Wu J; Pan C; Brown M; Vallim, T; Bennett BJ; Hazen SL. Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis. Journal of Lipid Research.
  1. Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D and Bennett BJ. High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis. G3 (Bethesda). 2014.
  2. Mei S, Yang X, Guo H, Gu H, ZhaL , Liu Z, Bennett BJ, He L, Cao W. A Small Amount of Dietary Carbohydrate Can Promote the HFD-Induced Insulin Resistance to a Maximal Level. 2014 (PLOS One, in press)
  1. O’Connor A, Quizon PM, Albright JE, Lin FT, Bennett BJ. Responsiveness of cardiometabolic-related microbiota to diet is influenced by host genetics. 2014 (Mammalian Genome, in press)
  1. Albright J, Quizon P, Lusis AJ, Bennett BJ. Genetic Network Identifies Novel Pathways Contributing to Atherosclerosis Susceptibility in the Innominate Artery. 2014 (BMC Medical Genomics, in press)
  1. Miller CA, Corbin KD, Costa KA, Zhang S, Zhao X, Galanko JA, Blevins T, Bennett BJ, O’Connor A, Zeisel SH Effect of egg ingestion on TMAO production in humans: a randomized controlled, dose-response study. Am J Clin Nutr. 2014 Jun 18. pii: ajcn.087692. [Epub ahead of print])
  1. Ghazalpour A,* Bennett BJ,* Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ. Genetic control of metabolite levels in mouse liver: Relationships to transcript levels and cardiometabolic traits. Mol Syst Biol. 2014 May 23;10(5):730. [*co-first authors]
  1. Hartiala J, Bennett BJ, Tang WH, Wang Z, Stewart AF, Roberts R, McPherson R, Lusis AJ, Hazen SL, Allayee H; CARDIoGRAM Consortium. Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-oxide, a Pro-Atherogenic Metabolite of Choline and L-Carnitine. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1307-13
  1. Kayashima Y, Tomita H, Zhilicheva S, Kim S, Kim H, Bennett BJ, Maeda N. Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice. PLoS One. 2014 Feb 20;9(2):e88274
  1. Rau CD, Wisniewski N, Orozco LD, Bennett B, Weiss J, Lusis AJ. Maximal information component analysis: A novel non-linear network analysis method. Front Genet. 2013;4:28.
  1. Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. Genome-wide association mapping of blood cell traits in mice. Mammalian genome. 2013, 24, 105-118.
  1. Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, Mehrabian M, Ursell LK, He A, Castellani LW, Zinker B, Kirby M, Drake TA, Drevon CA, Knight R, Gargalovic P, Kirchgessner T, Eskin E, Lusis AJ. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metab. 2013;17:141-152.
  1. Bennett BJ,* Vallim TQdA,* Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ. Trimethylamine-n-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metab. 2013;17:49-60. [*co-first authors]
  1. Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR. Systems genetic analysis of osteoblast-lineage cells. PLoS Genet. 2012;8:e1003150
  1. Plaisier CL, Bennett BJ, He A, Guan B, Lusis AJ, Reue K, Vergnes L. Zbtb16 promotes brown adipogenesis and substrate utilization: potential effect on obesity. Nutr Diabetes. 2012 September; 2(9): e46.
  1. Orozco LD,* Bennett BJ,* Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, Lusis AJ. Unraveling Inflammatory Responses using Systems Genetics and Gene-Environment Interactions in Macrophages. Cell, 2012. 151(3): p. 658-670. [*co-first authors]
  1. Ghazalpour, A, Rau CD, Farber CR, Bennett BJ Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012 Oct; 23 (9-10):680-92.
  1. Bennett, BJ, Orozco L, Kostem E, Erbilgin A, Dallinga M, Neuhaus I, Guan B, Wang X, Eskin E, Lusis AJ. High-resolution association mapping of atherosclerosis Loci in mice. Arterioscler Thromb Vasc Biol, 2012. 32(8): p. 1790-8.
  1. Ghazalpour A,* Bennett B,* Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG 2nd, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ. Comparative Analysis of Proteome and Transcriptome Variation in Mouse. PLoS Genet. 2011 Jun;7(6):e1001393. Epub 2011 Jun 9. [*co-first authors]
  1. Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, Lusis AJ. Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis. PLoS Genet. 2011 Apr; 7(4):e1002038. Epub 2011 Apr 7.
  1. Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison B, DuGar B, Feldstein AE, Britt EB, Fu X, Chung YM, Wu Y, Schauer P, Smith JD, Allayee H, Tang WH, DiDonato JA, Lusis AJ, Hazen SL. Gut flora dependent metabolism of dietary phosphatidylcholine contributes to cardiovascular disease. Nature 2011. 472, 57-63.
  1. Park CC, Gale GD, deJong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst Biol. 2011 Mar 16;5:43.
  1. Yao Y,* Bennett BJ,* Wang X, Rosenfeld ME, Giachelli C, Lusis AJ, Boström KI. Inhibition of Bone Morphogenetic Proteins Protects against Atherosclerosis and Vascular Calcification. Cir Research Epub June 24, 2010. [*co-first authors]
  1. Bennett BJ,* Farber CR,* Orozco L,* Kang H, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, Kirchgessner T, Pan C, Castellani LW, Kostem E, Furlotte N, Drake TA, Eskin E, Lusis AJ. A High Resolution Association Mapping Panel for the Dissection of Complex Traits in Mice. Genome Res. 2010 Feb; 20(2):281-90. Epub 2010 Jan 6. [*co-first authors]
  1. Bennett BJ, Wang SS, Wang XP, Wu X, Lusis AJ. Genetic Regulation of Atherosclerotic Plaque Size and Morphology in the Innominate Artery of Hyperlipidemic Mice. Arterioscler Thromb Vasc Biol. 2009; 29:348-355.
  1. Averill MM,* Bennett BJ,* Rattazzi M, Rodmyre RM, Kirk EA, Schwartz SM, Rosenfeld ME. Neither antioxidants nor genistein inhibit the progression of established atherosclerotic lesions in older apoE deficient mice. Atherosclerosis. 2009; 203(1): 82-88. [*co-first authors]
  1. Araujo JA, Barajas B, Kleinman M, Wang X, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel AE. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circulation Research. 2008; 102(5):589-596.
  1. Shaposhnik Z, Wang X, Weinstein M, Bennett BJ, Lusis AJ. Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2007;27(3):621-627.
  1. Bennett BJ, Scatena M, Kirk EA, Rattazzi M, Varon RM, Averill M, Schwartz SM, Giachelli CM, Rosenfeld ME. Osteoprotegerin inactivation accelerates advanced atherosclerotic lesion progression and calcification in older ApoE-/- mice. Arterioscler Thromb Vasc Biol. 2006; 26(9): 2117-2124.
  1. Rattazzi M,* Bennett BJ,* Bea F, Kirk EA, Ricks JL, Speer MY, Schwartz SM, Giachelli CM, and Rosenfeld ME. Calcification of Advanced Atherosclerotic Lesions in the Innominate Arteries of ApoE Deficient Mice: Potential Role of Osteogenic Cells. Arterioscler Thromb Vasc Biol. 2005 Jul; 25(7): 1420-5. Epub 2005 Apr 21. [*co-first authors]
  1. Bea F, Blessing E, Bennett BJ, Kuo CC, Campbell LA, Kreuzer J, Rosenfeld ME. Chronic inhibition of cyclooxygenase-2 does not alter plaque composition in a mouse model of advanced unstable atherosclerosis. Cardiovasc Res. 2003 Oct 15;60(1):198-204.
  1. Bea F, Blessing E, Bennett B, Levitz M, Wallace EP, Rosenfeld ME. Simvastatin promotes atherosclerotic plaque stability in apoE-deficient mice independently of lipid lowering. Arterioscler Thromb Vasc Biol 2002 Nov 1;22(11):1832-7.

Other peer reviewed articles:

  1. Rosenfeld ME, Averill MM, Bennett BJ, Schwartz SM. Progression and disruption of advanced atherosclerotic plaques in murine models. Curr Drug Targets. 2008;9(3):210-216.
  1. Bennett BJ, Romanoski CE, Lusis AJ. Network-centered view of coronary artery disease. Expert Rev Cardiovasc Ther. 2007; 5(6): 1095-1103.

Published Abstracts:

  1. Identification of Genetic Regulators of the Atherosclerosis-Associated Metabolite Trimethylamine-N-Oxide in the Diversity Outbred Mice Population. Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D and Bennett BJ. Arteriosclerosis Thrombosis and Vascular Biology. 2015
  1. Network Analysis of Pathways Associated with Genetic Regulation of Trimethylamine-N-Oxide. Smallwood T, Lamb A, Wright G, Bennett BJ. Arteriosclerosis Thrombosis and Vascular Biology. 2015
  1. A locus on Chromosome 6 in Diversity Outbred Mice Suggests Osteogenic Regulation of Dystrophic Cardiac Calcinosis. Einagheeb M, O’Connor A, Smallwood T, Bennett BJ. Arteriosclerosis Thrombosis and Vascular Biology. 2015
  1. Parks BW, Bennett BJ, Pan C, Krauss RM, GargalovicP, Kirchgessner T, Lusis AJ. High-dimensional genetic analysis of lipoprotein composition and size in the mouse. Arteriosclerosis Thrombosis and Vascular Biology. 2015
  1. Mapping metabolic traits in the diversity outbred mouse population. Bennett BJ, Smallwood T, Quizon P, Pomp D. FASEB J April 2014 28:818.12
  1. Towards nutrigenomics: studies to identify gene-diet interactions affecting susceptibility to cardiovascular disease. Bennett BJ, Corbin K, Smallwood T, O’Connor A, Zeisel S. FASEB J April 2014 28:373.4
  1. Diet and genetic-induced differences in the intestinal microbiome relate to cardiometabolic phenotype. O’Connor A, Lin F, Quizon P, Nestor A, Albright J, Bennett BJ. FASEB J April 2014 28:637.13
  1. Packard R, Bennett BJ, Civelek M, Pan C, Davis R, Lusis AJ. Systems Genetics Analysis Of Atherosclerosis Using A Hybrid Mouse Diversity Panel. Circulation 2013
  1. Bennett BJ, Farber CR, Orozco L, Lusis AJ. High Resolution Genetic Mapping Strategies for Metabolic Disease in Mice: Towards Association Based Studies. Circulation. 2008;118:S566
  1. Araujo JA, Barajas B, Kleinman M, Wang XP, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel A. Ambient particulate pollutants in the ultrafine range promote atherosclerosis and systemic oxidative stress. Arteriosclerosis Thrombosis and Vascular Biology. 2007; 27: E39.
  1. Averill MM, Bennett BJ, Varon RM, Rattazzi M, Rosenfeld ME. Resistance of advanced atherosclerotic lesions in older apolipoprotein E-deficient mice to dietary antioxidant treatment. Arteriosclerosis Thrombosis and Vascular Biology. 2006; 26: E100.
  1. Bennett BJ, Kirk EA, Rattazzi M, Varon R, Averill M, Giachelli C, Rosenfeld ME. Inactivation of matrix gla protein promotes chondroplastic conversion and calcification of atherosclerotic lesions in apolipoprotein E deficient mice. Arteriosclerosis Thrombosis and Vascular Biology. 2006;26: E94.
  1. Bennett BJ, Varon R, Averill M, Rattazzi M, Kirk E, Giachelli C, Rosenfeld ME. Dietary supplementation with genistein reduces aortic calcium content but does not inhibit the progression of advanced atherosclerotic lesions in older ApoE-/- mice. Arteriosclerosis Thrombosis and Vascular Biology. 2006;26:E100-E101.
  1. Scatena M, Bennett B, Hyunh D, Rosenfeld ME, Giachelli CM. Osteoprotegerin: A Modulator of Vascular and Inflammatory Cell Behavior. Abstracts of the 7th Annual Conference on Arteriosclerosis, Thrombosis, and Vascular Biology. Arterioscler Thromb Vasc Biol. 2006;26
  1. Bennett BJ, Rattazzi M, Kirk EA, Bea F, Speer MY, Giachelli CM, Rosenfeld ME. Chondrocyte-like cells and calcification of advanced atherosclerotic lesions in the innominate arteries of older ApoE-null mice. Arteriosclerosis Thrombosis and Vascular Biology. 2004;24:P427.
  1. Rattazzi M, Bennett B, Bea F, Campbell LA, Kuo CC, Pauletto P, Giachelli CM, Rosenfeld ME. Infection of macrophages with Chlamydia pneumoniae may contribute to vascular calcification and the conversion of smooth muscle cells to an osteoblast/chondrocyte-like phenotype. Arteriosclerosis Thrombosis and Vascular Biology. 2004;24:P432.
  1. Bennett B, Ronan AM, Tagliaferro AR. Dietary fat, DHEA, and substrate utilization. American Journal of Clinical Nutrition. 1997; 66: 75.

In Press

  1. Zhou X, Crow AL, Spindler TJ, Hartiala J, Barsky LW, Bennett BJ, Parks BS, Ghazalpour A, Eskin E, Jian R, Epstein JA, Lusis AJ, Adams GB, Allayee H. The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice.
  1. Orozco L , Morselli M, Rubbi L, Guo W, Go J, Shi H Furlotte NA, Lopez D, Bennett BJ, Farber CR, Ghazalpour A, Lusis AJ, Pellegrini M. Epigenome-wide association of complex metabolic traits in mice

Submitted

  1. Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard R, Eskin E, Kirchgessner T, Hazen S, Gargalovic P, Lusis AJ. Genetic architecture of atherosclerosis in mice: A systems genetics analysis of common inbred strains

Invited Presentations

  • Using system genetic approaches to understand gene x diet interactions. Fralin Translational Obesity Research Center, Virginia Tech University. April, 2015.
  • Gene-diet-environment Interactions in Chronic Metabolic Diseases. Nutrition and the Science of Disease Prevention: A systems approach to support metabolic health. The New York Academy of Sciences, April, 2015
  • Systems Genetic studies of Atherosclerosis and the novel Plasma Metabolite trimethylamine N-oxide (TMAO). International Mammalian Genome Society. Bar Harbor, ME. October 2014
  • Towards nutrigenomics: studies to identify gene-diet interactions affecting susceptibility to cardiovascular disease. Experimental Biology. San Diego, California. April 2014
  • Genetic and Metabolite Pathways Regulating Atherosclerosis. Presented at translating Application of Novel Approaches to Metabolic Disease and Oncology Research Symposium. Sponsored by Crown Bioscience and the David H. Murdock Research Institute. Kannapolis, NC, January 2014
  • Trimethylamine N-oxide (TMAO) Metabolism and Atherogenesis: Genetic and Dietary Regulation. American Heart Association Scientific Sessions. Dallas, Texas November, 2013
  • Unifying genetic and metabolite pathways regulating atherosclerosis. Wake Forest Department of Pathology, Winston Salem, NC. February, 2013
  • Diet, genes and bugs: How do choline metabolites affect atherosclerosis. UNC McAllister Heart Institute. University of North Carolina, Chapel Hill, NC. April 2013
  • Nutrigenomics: Understanding how diet influences gene expression and disease susceptibility. Department of Genetics/Curriculum in Genetics & Molecular Biology Scientific Retreat At The Beach. Myrtle Beach, SC. September 2012
  • Systems Genetic Approaches for Identification of Atherosclerosis Susceptibility Genes. Gordon Research Conference on Atherosclerosis. NH. June 2009.

Poster Presentations

  1. Identification of Genetic Regulators of the Atherosclerosis-Associated Metabolite Trimethylamine N-oxide in the Diversity Outbred Mouse Population. Smallwood T, Gatti DM, Quizon P, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ. NIEHS Population-Based Rodent Resources for Environmental Health Sciences Meeting. March 2015
  1. High-Resolution Genetic Mapping of Atherosclerosis in the Diversity Outbred Mouse Population Smallwood T, Gatti DM, Quizon P, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ. IMGS meeting, Bar Harbor Me October 2014
  1. Mapping cardiometabolic traits in the diversity outbred mouse population. Smallwood T, Quizon P, Hua K, Pomp D, Bennett BJ. Experimental Biology. San Diego, California. April 2014
  1. Mapping metabolic traits in the Diversity Outbred Mouse Population, Smallwood T, Quizon P, Hua K, Pomp D, Bennett BJ, International Mammalian Genomics Conference, September 15-18th, 2013.
  1. High-Resolution Association Mapping of Atherosclerosis Loci in Mice. Bennett BJ, Davis RC, Lusis AJ. Kern Aspen Lipid Conference, Aspen, CO. August, 2012
  1. Complex regulation of trimethylamine-N-oxide, a bacterial metabolite associated with atherosclerosis, in humans and mice. Bennett BJ, Vallim T, Wang Z, Qi H, Hazen S, Lusis AJ. Kern Aspen Lipid Conference, Aspen, CO. August 2011
  1. Common variations of the FMO3 gene contribute to atherosclerosis in female mice by influencing TMAO levels. Bennett BJ, Orozco O, Wang Z, Ghazalpour, Kostem E, Hazen S, Lusis AJ. Gordon Conference-Quantitative Genetics & Genomics From Genome to Phenotype. Galveston, TX. February 2011
  1. High Resolution Systems Genetics Studies of Lipoproteins Levels and Functional Properties in Mice. Bennett BJ, Castellani LW, Shih D, Orozco L, Farber CR, Lusis AJ. Kern Aspen Lipid Conference, Aspen, CO. August, 2009.
  1. Genetic networks induced by LPS and oxPAPC in primary mouse macrophages

Bennett BJ, Orozco L, Lusis AJ LIPID MAPS Meeting: Lipidomics Impact on Cell Biology, Structural Biochemistry and Immunopathology. San Diego, CA. May, 2009.

  1. High Resolution Genetic Mapping Strategies For Metabolic Disease in Mice. Bennett BJ, Farber CR, Orozco L, Kang H, Kostem E, Eskin E, Lusis AJ. FASEB Summer Research Conference: Molecular Mechanisms Involved in the Nutrient Control of Cellular Function. Carefree, AZ. July, 2008.
  1. Identification of Atherosclerosis Susceptibility and Cellular Morphology Loci in the Innominate Artery of Hyperlipidemic Mice Bennett BJ, Wang S, Wang X, Lusis AJ. 48th Annual Short Course on Medical and Experimental Mammalian Genetics The Jackson Laboratory, Bar Harbor ME. July, 2007.
  1. Identification of Atherosclerosis Susceptibility Loci in the Innominate Artery of Hyperlipidemic Mice Bennett BJ, Wang S, Wang X, Lusis AJ. Gordon Conference on Atherosclerosis, Il Cicco Italy. June, 2007.
  1. Lack of Osteoprotegrin Accelerates Progression of Advanced Atherosclerotic Lesions in the Innominate Arteries of Older ApoE-/- Mice. Bennett BJ, Kirk EA, Rattazzi M, Varon RM, Averill M, Giachelli CM, Rosenfeld ME. Keystone Conference on The Cellular Biology of Atherosclerosis (A7), Keystone, CO. January, 2005.

Teaching Record:

Course Director

  • 2014-2016 Course Director, NUTR 696: Advanced Nutritional Biochemistry-Nutrigenomics

7 graduate students, 2 credit hours.

Lecture at UNC

  • 2013 Lecturer, PHYI 702: Experimental Physiology of Health and Disease
  • 2013 Lecturer, PATH 667: Pathobiology of Cardiovascular Disease
  • 2012 Lecturer, BCB 710: Bioinformatics Colloquium, Network approaches to chronic diseases: genetic regulation of inflammation”. University of North Carolina, Chapel Hill
  • 2012 Lecturer, Genetics Department Research Colloquia “Cardiovascular disease: What I eat vs who I am. Modeling gene x diet interactions”

Lecture Prior to UNC

  • 2009 Guest Lecturer, CM222, “Mouse Models of Genetics” University of California, Los Angeles
  • 2005 Guest Lecturer, Nutrition 522, “Nutrition and Metabolism” University of Washington
  • 2003 Teaching Assistant, Nutrition 300, “Nutrition for Today” University of Washington
  • 1995-1996 Teaching Assistant, Nutrition “Food and People” University of New Hampshire

Trainee Mentoring-Current

Graduate Students

University of North Carolina, Chapel Hill- PhD Students

  • 2014-Alisha Coffey, Student Curriculum in Genetics and Molecular Biology, UNC

Chapel Hill.

Role: Co-mentor with Praveen Sethupathy

Project: microRNA regulation of FGF21

  • 2012-2015Tangi Smallwood, PhD Student Curriculum in Genetics and Molecular Biology,

UNC Chapel Hill.

Role: mentor.

Project title: Identification of genetic loci regulating atherosclerosis susceptibility

QTL mapping in a diet-induced model of atherosclerosis using a genetically diverse, outbred mouse population.

Top View