Bone growth and remodeling guided notes
Name: ______
Important Vocabulary
Osteocyte –
Osteoblast –
Osteoclast –
Mnemonic:
Bone growth and development
• Embryonic skeleton (A) is made of ______
• As a fetus (B),
• Osteoblasts form a ______around the diaphysis
• Osteoclasts ______in center of diaphysis
• Osteoblasts ______in the diaphysis
• Cartilage in other areas continues to ______
• As a newborn (C),
• ______
• ______
• Throughout childhood (D) and adolescence (E)
• ______
• ______(compact in diaphysis and spongy in epiphyses)
Growth in bone length
Bone growth in width
• Bones grow in width using a process called ______
• Osteoblasts ______secrete bone matrix
• Osteoclasts ______dissolve bone, enlarging the cavity.
• The osteoblasts create new bone at a slightly faster rate than the osteoblasts destroy
bone. This means the bones get wider and slightly thicker as they grow.
Think, Pair, Share
Where in the bone does bone deposition (bone building) occur?
Where does cartilage grow?
Where is bone resorbed?
Regulation of Bone Growth
Hormones regulate bone growth during youth.
• ______(secreted by pituitary) is the primary hormone responsible for bone growth in infancy and childhood
• ______(secreted by testes / ovaries)
• Cause a growth spurt in adolescence
• Cause the masculinization / feminization of the skeleton
• Later cause epiphyseal plate closure
Although most bones stop growing in late teens, some of your facial bones (e.g. nose, jaw) grow throughout life.
Compared to females, male skeletons have
• Heavier bones
• Enlarged rib cages
• Smaller pelvic opening
• Larger brow, mandible, and occipital protuberance
Regulation of Bone Remodeling
Bone remodeling is controlled by two factors:
• ______– determines ______more deposition or resorption occurs
• ______– determines ______more bone is needed
Although the role of mechanical stress (how much tension and compression bones experience) is not fully understood we do know that:
• ______
• ______