BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
Janet P. Tate / POSITION TITLE
Director Biostatistics Core
Co-Director cART and Risk Index Workgroups
eRA COMMONS USER NAME (credential, e.g., agency login)
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / MM/YY / FIELD OF STUDY
Southern Connecticut State University
University of Connecticut
Harvard School of Public Health / BS
MPH
ScD / 1981
1997
2010 / Chemistry
Epidemiology/Statistics
Epidemiology/Statistics

A. Personal Statement

Briefly describe why your experience and qualifications make you particularly well-suited for your role (e.g., PD/PI, mentor, participating faculty) in the project that is the subject of the application.

Dr. Janet Tate joined the Veterans Aging Cohort Study (VACS) in July 2008 as a contract biostatistician. Since that time she has become a vital part of the VACS team and has completed her doctorate in Epidemiology at Harvard School of Public Health. Her dissertation was on prognostic models in HIV infection using VACS data—a core analytic activity of our study. Having demonstrated her analytic and leadership ability, Dr. Tate was appointed to the Yale faculty in April 2011 and became the Director of the VACS Biostatistics Core In this role she supervises four master level statisticians and coordinates the efforts of several other doctoral level consultants.She represents VACS on three major international collaborations as the liaison to ART-CC, NA-ACCORD, and HIV Causal and presents our work in international venues including CROI and the International Workshop on HIV Observational Databases. In addition to her own work Dr Tate has contributed to the success of other projects. She has the ability to elucidate the ideas of clinicians to formulate a research question and analytical plan. She then packages statistical findings in a way that is readily interpretable, effectively using tables and graphs. Prior to joining VACS, Dr. Tate worked at Qualidigm for ten years doing study design and statistical analysis for quality improvement projects. In addition, Dr. Tate has done freelance statistical analysis for a variety of clients.

B. Positions and Honors

List in chronological order previous positions, concluding with the present position. List any honors. Include present membership on any Federal Government public advisory committee.

1986-1996 Analytical Chemist (86-90), Product Quality Analyst (90-92) Business Analyst (92-96), Uniroyal Chemical. Middlebury, CT

1996-1997 Research Fellow, University of Connecticut Health Center

1997-2007 Senior Health Information Analyst, Qualidigm, Middletown CT

1999- Assistant Clinical Professor, University of Connecticut Health Center

2000-2011 Biostatistician (Consultant); Connecticut Childrens' Medical Center

2008-2011 Biostatistician, Veterans Aging Cohort Study, Veterans Administration/Yale University (.6 FTE)

2008-2011 Biostatistician, University of Connecticut Health Center (.1 FTE)

2011- Associate Research Scientist, Yale University School of Medicine

Honors

2005 James Q Cannon Memorial Scholarship

1992 Quality Award: Product Excellence Team Concept (quality and yield optimization)

1991 Technical Achievement:TMQ Characterization and Increased Production Capacity

1990 Tech Expo, Best Paper: Recent Developments in the Characterization of TMQ Antioxidants

1987 Technical Achievement: Reduced variability of Vitavax assay method.

C. Selected Peer-reviewed Publications

NIH encourages applicants to limit the list of selected peer-reviewed publications or manuscripts in press to no more than 15. Do not include manuscripts submitted or in preparation. The individual may choose to include selected publications based on recency, importance to the field, and/or relevance to the proposed research. When citing articles that fall under the Public Access Policy, were authored or co-authored by the applicant and arose from NIH support, provide the NIH Manuscript Submission reference number (e.g., NIHMS97531) or the PubMed Central (PMC) reference number (e.g., PMCID234567) for each article. If the PMCID is not yet available because the Journal submits articles directly to PMC on behalf of their authors, indicate "PMC Journal - In Process." A list of these Journals is posted at: http://publicaccess.nih.gov/submit_process_journals.htm. Citations that are not covered by the Public Access Policy, but are publicly available in a free, online format may include URLs or PMCID numbers along with the full reference (note that copies of publicly available publications are not accepted as appendix material.)

1.  Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, Fiellin DA, Vanasse GJ, Butt AA, Rodriguez-Barradas MC, Gibert C, Oursler KA, Deeks SG, Bryant K, and the VACS Project Team. Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV? Clin Infect Dis 2012; Feb 15 (Epub ahead of print). [PMID: 22337823]

2.  Tetrault JM, Tate JP, McGinnis KA, Goulet JL, Sullivan LE, Bryant K Justice AC, Fiellin DA for the Veterans Aging Cohort Study Project Team. Hepatic safety and antiretroviral effectiveness in HIV-infected patients receiving naltrexone. Alcohol Clin Exp Res 2012 Feb; 36(2):318-324. [PMID: 21797892]

3.  Park LS, Tate JP, Justice AC, Lo Re V, Lim JK, Brau N, Brown ST, Butt AA, Gibert C, Goetz MB, Rimland D, Rodriguez-Barradas MC, Dubrow R. FIB-4 index is associated with hepatocellular carcinoma risk in HIV-infected patients. Cancer Epidemiol Biomarkers Prev 2011 Dec; 20(12):2512-2517. [PMID: 22028407]

4.  Vanasse GJ, Jeong JY, Tate J, Bathulapalli H, Anderson D, Steen H, Fleming M, Mattocks K, Telenti A, Fellay J, Justice AC, Berliner N. A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease. Blood 2011 Nov 17; 118(20):5401-5408. [PMID: 21926355]

5.  Lo Re V, Lim JK, Goetz MB, Tate J, Bathulapalli H, Klein MB, Rimland D, Rodriguez-Barradas MC, Butt AA, Gibert CL, Brown ST, Kidwai F, Brandt C, Dorey-Stein Z, Reddy KR, Justice AC. Validity of diagnostic codes and liver-related laboratory abnormalities to identify hepatic decomposition events in the Veterans Aging Cohort Study. Pharmacoepidemiol Drug Saf 2011 Jul; 20(7):689-699. [PMID: 21626605]

6.  Womack JA, Goulet JL, Gibert C, Brandt C, Chang CC, Gulanski B, Fraenkel L, Mattocks K, Rimland D, Rodriguez-Barradas MC, Tate J, Yin MT, Justice AC; for the Veterans Aging Cohort Study Project Team. Increased risk of fragility fractures among HIV infected compared to uninfected male veterans. PLoS One 2011 Feb 16; 6(2):e17217. [PMID: 21359191]

7.  Ohl M, Tate J, Duggal M, Skanderson M, Scotch M, Kaboli P, Vaughan-Sarrazin M, Justice A. Rural residence is associated with delayed care entry and increased mortality among veterans with human immunodeficiency virus infection. Med Care 2010 Dec; 48(12):1064-1070. [PMID: 20966783]

8.  Meehan TP, Van Hoof TJ, Giannotti TE, Tate JP, Elwell A, Curry M, Petrillo MK. A descriptive study of educational outreach to promote use of quality improvement tools in primary care private practice. Am J Med Qual 2009 Mar-Apr; 24(2):90-98. [PMID: 19182046]

9.  Holmboe ES, Wang Y, Meehan TP, Tate JP, Ho SY, Starkey KS, Lipner RS. Association between maintenance of certification examination scores and quality of care for medicare beneficiaries. Arch Intern Med 2008 Jul 14; 168(13):1396-1403. [PMID: 18625919]

10.  Holmboe ES, Wang Y, Tate JP, Meehan TP. The effects of patient volume on the quality of diabetic care for Medicare beneficiaries. Med Care 2006 Dec; 44(12):1073-1077. [PMID: 17122710]

11.  Meehan TP, Wang Y, Tate JP, Curry M, Elwell A, Petrillo MK, Holmboe ES. Improving the quality of preventive cardiovascular care provided by primary care physicians: insights from a US Quality Improvement Organization. Int J Qual Health Care 2006 Jun; 18(3):186-94. [PMID: 16527866]

12.  Meehan TP, Tate JP, Holmboe ES, Teeple EA, Elwell A, Meehan RR, Petrillo MK, Huot SJ. A collaborative initiative to improve the care of elderly Medicare patients with hypertension. Am J Med Qual 2004 May-Jun; 19(3):103-111. [PMID: 15212315]

13.  McCormick D, Gurwitz JH, Goldberg RJ, Becker R, Tate JP, Elwell A, Radford MJ. Prevalence and quality of warfarin use for patients with atrial fibrillation in the long-term care setting. Arch Intern Med 2001 Nov 12; 161(20):2458-2463. [PMID: 11700158]

14.  Metersky ML, Tate JP, Fine MJ, Petrillo MK, Meehan TP. Temporal trends in outcomes of older patients with pneumonia. Arch Intern Med 2000 Dec 11-25; 160(22):3385-91. [PMID: 11112230]

15.  Meehan TP, Chua-Reyes JM, Tate J, Prestwood KM, Scinto JD, Petrillo MK, Metersky ML. Process of care performance, patient characteristics, and outcomes in elderly patients hospitalized with community-acquired or nursing home-acquired pneumonia. Chest 2000 May; 117(5):1378-1385. [PMID: 10807825]

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D. Research Support

List both selected ongoing and completed research projects for the past three years (Federal or non-Federally-supported). Begin with the projects that are most relevant to the research proposed in the application. Briefly indicate the overall goals of the projects and responsibilities of the key person identified on the Biographical Sketch. Do not include number of person months or direct costs.

Ongoing Research Support

Veterans Aging Cohort Study 4/1/2011 - present

Awarding Agency: NIAAA

PI: Amy C. Justice

Role: Director of Biostatistics

Completed Research Support

Veterans Aging Cohort Study 7/1/2008 – 3/31/2011

Awarding Agency: NIAAA

PI: Amy C. Justice

Role: Consultant Bio-statistician

2 T32 ES07069-26 9/1/2005 – 8/31/2007

Awarding Agency: NIEHS

PI: David Christiani, MD, MPH, MS

Title: Training Program in Environmental Epidemiology

Role: Student

RFP#2009-0914 for Biomedical Research, 10/1/2009-6/30/2010

Awarding Agency: Department of Public Health, State of Connecticut

PI: Bruce Liang MD, Director Calhoun Cardiology Center, University of Connecticut

Title: Development of a new blood test for patients with heart failure

Role: Consultant Bio-statistician

PHS 398/2590 (Rev. 06/09) Page Biographical Sketch Format Page