BDS Ist YEAR EXAMINATION 2008-09 s5

Supplementary MBBS I (First) Professional Examination 2015-16

Course Code: MBS103 Paper ID: S322208

Biochemistry -I

Time: 2 Hours 40 Minutes Max Marks: 40

Note: Attempt all questions. Draw proper diagrams to support your answer.

Part ‘B’

1. Briefly discuss the synthesis of thyroid hormones. What are the thyroid function tests? (6+4)

2. Write short notes on any six of the following: (5x6=30)

a) Uncouplers of oxidative phosphorylation

b) Competitive inhibition and its significance

c) 2,3-Bisphosphoglycerate and its significance

d) Carnitine shuttle

e) Important products derived from tyrosine

f) Transamination

g) Gibbs- Donnan membrane equilibrium

Supplementary MBBS I (First) Professional Examination 2015-16

Roll No. Student’s Name

Student’s Signature Invigilator’s Signature

Course Code:MBS103 Paper ID: S322208

Biochemistry - I

Part ‘A’

Time: 20 Minutes Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

Q.1 The following is a pseudo ketone body:

a) Acetoacetate

b) -hydroxybutyrate

c) Acetone

d) None of the above

Q.2 The end product of amino acid catabolism is:

a) Urea b) Creatine

c) Creatinine d) Uric acid

Q.3 The following is antagonistic to insulin:

a) Growth hormone

b) Epinephrine

c) Cortisol

d) All of the above

Q.4 The following is a non-essential amino acid:

a) Valine

b) Leucine

c) Isoleucine

d) Alanine

Q.5 Glutathione contains:

a) Cysteine

b) Glycine

c) Glutamate

d) All of the above

Q.6 Cardiac isoenzyme is:

a) CPK-1

b) CPK-2

c) CPK-3

d) None of the above

Q.7 Na/K – pump is an example of:

a) Facilitated diffusion

b) Primary active transport

c) Secondary active transport

d) Simple diffusion

Q.8 Cystic fibrosis affects the following channel:

a) Sodium b) Potassium

c) Chloride d) Calcium

Q.9 Bad cholesterol is:

a) HDL

b) VLDL

c) LDL

d) None of the above

Q.10 Phrenoderma is due to a deficiency of:

a) Essential amino acids

b) Essential fatty acids

c) Dietary fibres

d) Purines

Q.11 The precursor for gluconeogenesis is:

a) Alanine

b) Lactate

c) Glycerol

d) All of the above

P.T.O.

Q.12 Glucose-6phosphate dehydrogenase deficiency may result in:

a) Aplastic anemia

b) Nutritional anemia

c) Hemolytic anemia

d) Polycythemia

Q.13 Storage form of lipids is:

a) Phospholipid

b) Fatty acid

c) Cholesterol

d) Triacylglycerol

Q.14 Oxygen-dissociation curve of myoglobin is:

a) Rectangular hyperbola

b) Parabola

c) Sigmoid

d) Linear

Q.15 The following is an ‘activated amino acid’:

a) Glutamate

b) Asparagine

c) S-adenosyl methionine

d) Proline

Q.16 The following is a second messenger:

a) Ca

b) cAMP

c) Diacylglycerol

d) All of the above

Q.17 Adenosine is:

a) A nitrogenous base

b) A nucleoside

c) A nucleotide

d) A nucleic acid

Q.18 The following enzyme is used therapeutically:

a) Asparaginase

b) Hyaluronidase

c) Streptokinase

d) All of the above

Q.19 Deficiency of HGPRTase results in:

a) Gaucher’s disease

b) Hyperammonemia type I

c) Lesch-Nyhan syndrome

d) Alkaptonuria

Q.20 Fluoride inhibits:

a) Enolase

b) Pyruvate dehydrogenase

c) Fumarase

d) Glucokinase