Bashar M Al-Taani

Faculty of Pharmacy

JordanUniversity of Science and Technology

Irbid – Jordan

Telephone: (962-2) 7201000 Extension 23444 (Work)

(962-6) 5350665 (Home)

(079) 5562651(Mobile)

(962-2) 7201075 (Fax)

E-mail:

Education:

August 1993 – May 1999

Purdue University Ph-D

School of Pharmacy and Pharmacal Sciences Advisor: Dr Garnet E Peck

Department of Industrial and Physical Pharmacy

West Lafayette, IN47906

August 1986 – January 1991

Faculty of Pharmacy B. S. Pharmacy

JordanUniversity of Science and Technology

Irbid – Jordan

Experience:

Dec 2008 – Now

Department of Pharmaceutical TechnologyAssociate Professor

Faculty of Pharmacy

JordanUniversity of science and Technology

Irbid – Jordan

May 1999 – Dec 2008

Department of Pharmaceutical TechnologyAssistant Professor

Faculty of Pharmacy

JordanUniversity of science and Technology

Irbid – Jordan

August 1993 – May 1999

Department of Industrial and Physical Pharmacy Graduate Student

PurdueUniversity Conduct original research in

West Lafayette, IN47906 the pharmaceutical sciences

pursuant to the degree of PhD

June 1991 – August 1993

The United Pharmaceutical Medical Representative

Manufacturing Company

Amman – Jordan

January 1991 – June 1991

Bashar Pharmacy R. Pharmacist

Irbid – Jordan

June 1990 – August 1990

Arab Pharmaceutical Company Summer Internship in

Sult – Jordan Pharmaceutical Manufacturing

Publication

Physical Interaction of Aqueous Coating Solutions with Tablet Cores during Pharmaceutical Coating, pH-D thesis, May 1999, PurdueUniversity, West Lafayette, IN47907, USA

Bashar M. Al-Taani and Bassam M. Tashtoush, “Effect of microenvironment pH of swellable and erodable buffered matrices on the release characteristics of diclofenac sodium” AAPS PharmSciTech 2003; 4 (3) article 43, 343 - 348

B. M. Tashtoush and B. M. Al-Taani “HPLC determination of naproxen in plasma” Pharmazie 58 (9) (2003): 613 –614.

Mohammad M. Fares and Bashar Alta’ani, “Graft copolymerization onto chitosan-I. Grafting of ethylmethacrylate using ceric ammonium nitrate as an initiator” Acta Chem. Slov. 2003, 50, 275 – 285.

A.M.Qandil, B.M.Tashtoush, B.M.Al-Taani, S.M.Al-Nabulsi and F.Al-Zogoul,Simultaneous RP-LC Determination of Ketorolac and its Piperazinylalkyl Ester Prodrugs ChromatographiaVolume 67, Numbers 3-4 / February, 2008 287-291

Amjad Qandil, Soraya Al-Nabulsi, Bashar Al-Taani and Bassam Tashtoush, "Synthesis of Piperazinylalkyl Ester Prodrugs of Ketorolac and their In Vitro Evaluation for Transdermal Delivery" Drug Development and Industrial Pharmacy, 34:1054–1063, 2008

Bashar Al-Taani, Mai S. Khanfar, Mutaz Sheikh Salem & Alsayed Sallam, "Release behaviour of diclofenac sodium dispersed in Gelucire and encapsulated with alginate beads" J Microencapsul. 2010 Feb;27(1):10-3.

Bashar Al-Taani, Mutaz Sheikh-Salem and Sura Al Taani, "Influence of Polyvinyl Pyrrolidone Addition during Crystallization on the Physicochemical Properties of Mefenamic Acid Crystals", Jordan Journal of Pharmaceutical Sciences, 2, 1, 86-98, 2008

Amjad M. Qandil, Aiman A. Obaidat, Muaadh A. Mohammed Ali, Bashar M. Al-Taani, Bassam M. Tashtoush, Nawzat D. Al-Jbour, Mayyas M. Al Remawi, Khaldoun A. Al-Sou’od, Adnan A. Badwan, "Investigation of the Interactions in Complexes of Low Molecular Weight Chitosan with Ibuprofen" J Solution Chem (2009) 38: 695–712

Athamneh NA, Tashtoush BM, Qandil AM, Al-Tanni BM, Obaidat AA, Al-Jbour ND, Qinna NA, Al-Sou'od K, Al-Remawi MM, Badwan AA. “A new controlled-release liquid delivery system based on diclofenac potassium and low molecular weight chitosan complex solubilized in polysorbates”Drug Dev Ind Pharm. 2012 Aug 9. [Epub ahead of print]

Tashtoush BM, Bennamani AN, Al-Taani BM,“Preparation and characterization of microemulsion formulations of nicotinic acid and its prodrugs for transdermal delivery”Pharm Dev Technol. Pharm Dev Technol. 2013 Jul-Aug;18(4):834-43

Rana M ObaidatBashar M AltaaniAnoud AilabouniEffect of different polymeric dispersions on In-vitro dissolution rate and stability of celecoxib class II drugJ Polym Res (2017) 24: 58

Gubran Khalil MohammedRana M ObaidatShereen Assaf Bashar M AltaaniFORMULATIONS AND TECHNOLOGIES IN GROWTH HORMONE DELIVERY

International Journal of Pharmacy and Pharmaceutical Sciences, [S.l.], p. 1-12, july 2017.

Rana M ObaidatBashar M AltaaniHanan Al-quraanEFFECT OF SELECTED POLYMERS ON DISSOLUTION AND STABILIZATION OF AMORPHOUS FORM OF MELOXICAM International Journal of Pharmacy and Pharmaceutical Sciences, [S.l.], p. 33-42, July 2017.

AlSheyyab RY, Al-Taani BM, Obeidat RM, Alsmadi MM, Masaedeh RK, Sabat RN. Delivery of Peptidic Gonadotropin Releasing Hormone AntagonistsCurr Drug Deliv. 2018;15(5):602-609.

Nusaiba Al-nemrawiNid’’A H. AlshraiedehAref ZayedBashar M AltaaniLow Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic FibrosisPharmaceuticals (Basel). 2018 Mar 8;11(1).

Amjad M. Qandil, Tamara J. Marji, Bashar M. Al-Taani, Aseel H. Khaled, Adnan A. BadwanDepolymerization of High Molecular Weight into a Predicted Low Molecular Weight Chitosan and Determination of the Degree of Deacetylation Coupled with Other Tests to Guarantee its Quality for Research UseJ. Excipients and Food Chem. 9 (2) 2018

Mai KhanfarBashar M AltaaniMo'tasem AlsmadiAref ZayedEnhancement of the dissolution and bioavailability from freeze-dried powder of a hypocholesterolemic drug in the presence of SoluplusPowder TechnologyVolume 329, 15 April 2018, Pages 25-32

Bashar M AltaaniMai KhanfarO.A. AlsuodEnhancement of the release of curcumin by the freeze-drying technique using inulin and neusilin as carriers international journal of applied pharmaceutics vol 10 issue 3 2018

Research Interests

-Pharmaceutical drug delivery

-Physicochemical characterization of pharmaceutical ingredients

-Tabletting and tablet coating

-Solubility and dissolution improvement of pharmaceutical ingredients

-Pharmaceutical formulation and pharmacokinetic studies

-Microencapsulation of drug for sustained drug delivery and Taste masking

-Nonoparticle formulations of small molecular weight molecule and peptide drugs for oral delivery

Skills:

-Tabletting including granulation, blending and screening.

-Tablet coating using side-vented Accela-Cota

-Accelerated stability study

-Preparation of free polymeric membranes

-Physical characterization of solutions:

1. Viscosity determination

2. Surface tension determination

3. Contact angle determination

4. Solution density

-Physical characterization of powders:

1. X-ray powder diffraction

2. Particle size and particle size distribution

3. Densities including true, bulk, and packed densities

4. Surface area analysis

5. Sorption isotherm

6. Moisture determination using Karl Fisher titration and loss

on drying

7. Hydration capacity determination

8. Thermal analysis including DSC and TGA

-Characterization of the solid dosage form

1. Mercury porosimetry

2. Compressibility using Heckel plots

3. Powder flowability and floodability

4. Tablet hardness, physical dimensions and friability

- HPLC analysis of biological samples

- Computer skills including Statistical software (SAS), Microsoft office, optimization software (Cyplex and Lindo), and Fortran 90 programming

Administration and Responsibilities

-Head of Department of pharmaceutical technology Sept 2008 – Sept 2018

-Assistant Dean for student affair Sept 2007 - Sept 2008

-Head of Department of pharmaceutical technology Sept 2005 – Sept 2007

-Faculty of pharmacy council.

-University council Sept. 2001 - 2002

-Department of pharmaceutical technology council Sept. 1999 – now

-Department higher education council

-Scientific committee

-Social committee

-Safety committee

-Faculty Supply and Lab. Committee

-Department research committee

-Member of Jordan Food and Drug Administration (JFDA) Committee for Bioequivalence Studies Evaluation and Appeals. 2008 – 2010.

-Member of committee to Update the regulation for registration of drugs in Jordan (2006)

-Member of University Central Tenders and supply committee (Sept 2010 – Sept 2012)

Organization:

American Association of Pharmaceutical Scientist (AAPS)

Rho Chi Pharmaceutical Honor Society

Controlled Release Society

Jordanian Pharmaceutical Association

Recipient of Scientist Research Fund from Ministry of Higher Education for the Project titled “Structured polymeric aggregates nano-particles based on chitosan for sustained release delivery of NSAIDs to children in liquid dosage form”

Recipient of Daniel Turnberg UK/Middle East Travel Award for the Year 2013

Teaching Experience:

-Phar. 354 Pharmaceutics II

-Phar. 451 Pharmaceutics III

-Phar. 453 Industrial Pharmacy

-Phar. 478 Community Pharmacy

-Phar. 551 Pharmaceutics IV

-Phar. 571 Pharmacy practice lab IV

-Phar. 701 Pharmaceutical Analysis

-Phar. 752 Pharmaceutical Dosage Form Technology

-Phar. 758 Drug Stability

-Phar. 792 Pharmaceutical Quality Control and Quality Assurance

-Phar. 853 Pharmaceutical Technology 2

-Phar. 401 Pharmaceutical Practical Training

-Phar. 788 Sterile Dosage Forms

-Phar. 458Pharmaceutical Technology

-Phar. 504Special Topics I

-Phar. 505 Special Topics II

-Pharm D 451Pharmaceutics II

-Pharm D 554 Pharmaceutics III

Workshop Taught

-Solubility and Dissolution Aspects of Preformulation Studies, Three Days Workshop.

-Formulation, Manufacture, and Control of Sterile Dosage Forms, Three Days Workshop

Contract Work

-Filling of liquid cyclosporin formulation into hard gelatin capsule under laminar air flow.

-Pilot bioequivence study of two naproxen formulations using rabitts under the fed and fast state.

-Pilot bioequivelant study of mefenamic acid prodrug using rabbits under the fed and fast state.

-Preparation and characterization of polymeric membranes for sustained release purposes

-Taste Masking of Azithromycin axelate by Microencapsulation

Thesis Supervised:

“Release of Tramadol HCl from Swellable and Erodable Polymers” by Rawda Yassin Al-Sheyab, Master Thesis, August 2000

“ Influence of Moisture on Hydrophilic Polymers and its Effects on the Stability of Cefadroxil” by Dima Ibrahim Al-Fayoumi, Master Thesis, 2001

“Crystallization of Mefenamic Acid in the Presence of Polymers” by Sura Ahmed Al-Taani, Master Thesis, April 2002.

“Microemulsion Formulation and Evaluation for Transdermal Drug Delivery” by Fadi Fakher Eldin, Master Thesis, September 2006.

“Synthesis and Evaluation of Keterolac Prodrugs for Transdermal Drug Delivery” by SuriaAl-Nabulsi, Master Thesis, December 2006.

“Sodium Hyaluronate Oligosaccharide Interaction with Gabapentin” by Nussiba Nemrawi, Master Thesis, June 2008.

“Chitosan Oligosaccharide Interaction with Diclofenac Potassium” by Neveen Athamneh,Master Thesis, June 2008.

“Transdermal Delivery of Ketorolac Using Microemulsion Vehicles” by AmaniAbuHial,Master Thesis, June 2008.

“Separation and Purification of Hydrophilic Polymers” by Tamara Merjey, Master Thesis, June 2008.

“Interaction of Low Molecular Weight Poly(Amino Acid) with Active Pharmaceutical Ingridients” by Samer Kharashkeh,Master Thesis, June 2008.

"Hydrolysis Kinetics of Nicotinic Acid Prodrugs" by Aliaa Al-Tarakji, Master Thesis, May 2009.

"Microencapsulation of venlafaxine hydrochloride using ethylcellulose for sustained release purpose", by Bouchra Gherissi, Master Thesis, March 2010.

"Preparation and Characterization of Microemulsion Formulatioms of Nicotinic Acid and Its Prodrugs for Transdermal Delivery" by Amina Bennamani, April 2010.

"Microencapsulation of Clarithromycin Using Eudragit S100 PolymerforTaste Masking" byMohammad Bahaa Majzoub May 2011.

"Microencapsulation of pregabalin usig ethylcellulose for sustained release purpose ", Haya Yasin, May 2011.

“Oral delivery of teriparatide using chitosan based nanoparticles” Suha Dadou, Oct 2013

“Preparation and characterization of new surfactant derived from Jojoba oil” Mohhanad Ahmad Kossa, December, 2014

“Preparation and evaluation of solid dispersion of celecoxib” Anoud Sameer Ailabouni. Jan, 2016

“In vitro evaluation of meloxicam in solid dispersion systems” Hanan Ameen Al Qura’an, Jan, 2016

“Enhancement of solubility of Atorvastatin through preparation of solid dispersion using supercritical fluid technology” Wlaa Ibrahim Malkawi, Jan, 2016

“Preparation and characterization of an oral norethindrone sustained release nano-particles formulation based on chitosan” Razan Hani Haddad, April, 2017

“Oral delivery of liraglutide using chitosan” Ruba Ibrahim Malkawi

“Enhancing dissolution of curcumin by solid dispersion method and freeze- drying technique using inulin and neusiln as carrier” Osama Mahmoud Abualsuod, May, 2017

“Dihydroergotamin chitosan nanoparticles for intranasal administration” Ahmad A. M. Alastal, May 2018

Courses Attended

-Evaluation and Teaching Technology Workshop – Basic Skills, JordanUniversity of Science and Technology 26 –28 June 1999

-Evaluation and Teaching Technology Workshop – The use of the internet in teaching, Jordan University of Science and Technology 15 –29 April 2000

-Evaluation and Teaching Technology Workshop – Measuring and Evaluation - Preparing Exams and Their Analysis, Jordan University of Science and Technology 26 –28 June 2000.

-Modern University Instructional Method – Electronic Learning, The Academic Development Center, Jordan University of Science and Technology 4 – 5 November 2007.

-Development of curriculum and study plan, Academic development and quality assurance center, Jordan University of Science and Technology, 19-20 Jan 2014.

-E-learning, Academic development and quality assurance center, Jordan University of Science and Technology, 9-10 Feb 2014.

-Online learning design, Academic development and quality assurance center, Jordan University of Science and Technology, 27-28 March 2018.

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Conferences Attended

-Inerfix 97

-World pharm98

-AAPS regional meeting, Chicago, 1999

-The Ninth Jordanian Pharmaceutical Association conference

-The Tenth Jordanian Pharmaceutical Association conference

-The Eleventh Jordanian Pharmaceutical Association conference

-The Twelfth Jordanian Pharmaceutical Association conference

-The New European CPMP and US FDA Notes for Guidance on Bioavailability and Bioequivalence. Lisbon, 2001.

-EUPOC 2004, Gargnano, Italy

- 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, March 2008

-Skin and Formulation, 3rd Symposium - Skin Forum, 10th Annual Meeting, Versailles, France 9-10 March 2009

-The 27th Scientific Conference of the Arab Union of Pharmacists, Damascus, Syria, 11-13 May 2010

-2010 FIP PSWC/AAPS Annual Meeting and Exposition, November 14-18, 2010, Ernest N Morial Convention Center, New orleans, Lousiana, USA.

-APS PharmSci 2011 - The Science of Medicines Dates: 31st August - 2nd, East Midlands Conference Centre, Nottingham United kindom

-2012 AAPS Annual Meeting and Expostion, October 14 -18, 2012, McCormick Place, Chicago, Illinois, USA

-GTCbio’s ProteinDiscovery Summit 2014 on October 23-24, 2014 in Boston, MA.

-2ndAnnual International Conference on Pharmaceutical Sciences,4-7 May 2015,Athens, Greece

-2016 AAPS Annual Meeting and Expostion, November 13–17, 2016 Colorado Convention Center, Denver, Colorado USA

-2017 AAPS Annual Meeting and Expostion, Nov 12 -15, 2017, San diego conventionn center, San Diago California

References:

Dr. Adnan Dakkuri

Dr. Mutaz Sheikh-Salem

Dr. Aiman Obaidat

Dr. Khloud Khamees and Others available upon request