Table S1.The101 isolates,their genetic markers and mating types used in this study, 35 isolates are MAT1-1, 65 isolates are MAT1-2.

No. / Species / Isolates / CaM / cnB / BenA / cytC / cnA / Mating types / Origins / Sources
/ A. fumigatus sensu lato / CYH5 / KC701232 / KF134051 / KJ527176 / KJ527270 / KJ527082 / 1-2 / Qinghai, China / sputum of IA patients
/ CYH10 / KC701235 / KF134054 / KJ527177 / KJ527271 / KJ527083 / 1-2 / Beijing, China / sputum of IA patients
/ CYH11 / KC701236 / KF134055 / KJ527178 / KJ527272 / KJ527084 / 1-2 / Beijing, China / sputum of IA patients
/ CYH21 / KC701239 / KF134058 / KJ527179 / KJ527273 / KJ527085 / 1-2 / Heilongjiang, China / sputum of IA patients
/ CYH23 / KC701203 / KF134020 / KJ527180 / KJ527274 / KJ527086 / 1-1 / Beijing, China / sputum of IA patients
/ CYH25 / KC701240 / KF134059 / KJ527181 / KJ527275 / KJ527087 / 1-1 / Beijing, China / sputum of IA patients
/ CYH39 / KC701204 / KF134021 / KJ527182 / KJ527276 / KJ527088 / 1-2 / Beijing, China / sputum of IA patients
/ CYH41 / KC701244 / KF134063 / KJ527183 / KJ527277 / KJ527089 / 1-2 / Hebei, China / sputum of IA patients
/ CYH42 / KC701245 / KF134064 / KJ527184 / KJ527278 / KJ527090 / 1-2 / Beijing, China / sputum of IA patients
/ CYH45 / KC701247 / KF134066 / KJ527185 / KJ527279 / KJ527091 / 1-2 / Beijing, China / sputum of IA patients
/ CYH46 / KC701248 / KF134067 / KJ527186 / KJ527280 / KJ527092 / 1-2 / Beijing, China / sputum of IA patients
/ CYH47 / KC701205 / KF134022 / KJ527187 / KJ527281 / KJ527093 / 1-1 / Hebei, China / sputum of IA patients
/ CYH50 / KC701249 / KF134068 / KJ527188 / KJ527282 / KJ527094 / 1-1 / Beijing, China / sputum of IA patients
/ CYH54 / KC701252 / KF134071 / KJ527189 / KJ527283 / KJ527095 / 1-2 / Beijing, China / sputum of IA patients
/ CYH55 / KC701253 / KF134072 / KJ527190 / KJ527284 / KJ527096 / 1-1 / Beijing, China / sputum of IA patients
/ CYH57 / KC701254 / KF134073 / KJ527191 / KJ527285 / KJ527097 / 1-2 / Beijing, China / sputum of IA patients
/ CYH58 / KC701206 / KF134023 / KJ527192 / KJ527286 / KJ527098 / 1-1 / Beijing, China / sputum of IA patients
/ CYH59 / KC701255 / KF134074 / KJ527193 / KJ527287 / KJ527099 / 1-2 / Hebei, China / sputum of IA patients
/ CYH60 / KC701256 / KF134075 / KJ527194 / KJ527288 / KJ527100 / 1-2 / Shanxi, China / sputum of IA patients
/ CYH83 / KC701258 / KF134077 / KJ527195 / KJ527289 / KJ527101 / 1-1 / Liaoning, China / sputum of non-IA patients
/ CYH3s2 / KC701259 / KF134078 / KJ527196 / KJ527290 / KJ527102 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s3 / KC701260 / KF134079 / KJ527197 / KJ527291 / KJ527103 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s5 / KC701262 / KF134081 / KJ527198 / KJ527292 / KJ527104 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s7 / KC701263 / KF134082 / KJ527199 / KJ527293 / KJ527105 / 1-1 / Beijing, China / sputum of IA patients
/ CYH3s9 / KC701208 / KF134025 / KJ527200 / KJ527294 / KJ527106 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s10 / KC701265 / KF134084 / KJ527201 / KJ527295 / KJ527107 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s18 / KC701209 / KF134026 / KJ527202 / KJ527296 / KJ527108 / 1-2 / Heilongjiang, China / sputum of non-IA patients
/ CYH3s20 / KC701211 / KF134028 / KJ527203 / KJ527297 / KJ527109 / 1-1 / Anhui, China / sputum of IA patients
/ CYH3s21 / KC701212 / KF134029 / KJ527204 / KJ527298 / KJ527110 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s25 / KC701273 / KF134092 / KJ527205 / KJ527299 / KJ527111 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s26 / KC701213 / KF134030 / KJ527206 / KJ527300 / KJ527112 / 1-1 / Beijing, China / sputum of IA patients
/ CYH3s31 / KC701277 / KF134096 / KJ527207 / KJ527301 / KJ527113 / 1-2 / Shanxi, China / sputum of non-IA patients
/ CYH3s33 / KC701214 / KF134031 / KJ527208 / KJ527302 / KJ527114 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s34 / KC701279 / KF134098 / KJ527209 / KJ527303 / KJ527115 / 1-1 / Beijing, China / sputum of IA patients
/ CYH3s35 / KC701280 / KF134099 / KJ527210 / KJ527304 / KJ527116 / 1-2 / Shandong, China / sputum of IA patients
/ CYH3s37 / KC701282 / KF134101 / KJ527211 / KJ527305 / KJ527117 / 1-2 / Hubei, China / sputum of non-IA patients
/ CYH3s38 / KC701283 / KF134102 / KJ527212 / KJ527306 / KJ527118 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s43 / KC701215 / KF134032 / KJ527213 / KJ527307 / KJ527119 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s46 / KC701286 / KF134105 / KJ527214 / KJ527308 / KJ527120 / 1-2 / Qinghai, China / sputum of IA patients
/ CYH13872 / KC701289 / KF134108 / KJ527215 / KJ527309 / KJ527121 / 1-2 / Shandong, China / soil
/ FRR 623 / KC701290 / KF134109 / KJ527216 / KJ527310 / KJ527122 / 1-1 / Indonesia / environment
/ NRRL 5587 / EF669922 / KF134037 / KJ527217 / KJ527311 / KJ527123 / 1-1 / India / soil
/ FRR 163 T / KC701220 / KF134038 / KJ527218 / KJ527312 / KJ527124 / 1-2 / Connecticut, USA / lung of chicken
/ CYH4 / KC701200 / KF134017 / KJ527219 / KJ527313 / KJ527125 / 1-2 / Beijing, China / sputum of IA patients
/ CYH6 / KC701233 / KF134052 / KJ527220 / KJ527314 / KJ527126 / 1-2 / Hebei, China / sputum of IA patients
/ CYH7 / KC701234 / KF134053 / KJ527221 / KJ527315 / KJ527127 / 1-1 / Beijing, China / sputum of IA patients
/ CYH13 / KC701201 / KF134018 / KJ527222 / KJ527316 / KJ527128 / 1-1 / Beijing, China / sputum of IA patients
/ CYH14 / KC701237 / KF134056 / KJ527223 / KJ527317 / KJ527129 / 1-2 / Beijing, China / sputum of IA patients
/ CYH16 / KC701238 / KF134057 / KJ527224 / KJ527318 / KJ527130 / 1-2 / Hebei, China / sputum of IA patients
/ CYH17 / KC701202 / KF134019 / KJ527225 / KJ527319 / KJ527131 / 1-1 / Tianjin, China / sputum of IA patients
/ CYH27 / KC701241 / KF134060 / KJ527226 / KJ527320 / KJ527132 / 1-2 / Beijing, China / sputum of IA patients
/ CYH36 / KC701242 / KF134061 / KJ527227 / KJ527321 / KJ527133 / 1-2 / Beijing, China / sputum of IA patients
/ CYH38 / KC701243 / KF134062 / KJ527228 / KJ527322 / KJ527134 / 1-2 / Hebei, China / sputum of IA patients
/ CYH43 / KC701246 / KF134065 / KJ527229 / KJ527323 / KJ527135 / 1-2 / Beijing, China / sputum of IA patients
/ CYH51 / KC701250 / KF134069 / KJ527230 / KJ527324 / KJ527136 / 1-2 / Beijing, China / BALF of IA patients
/ CYH53 / KC701251 / KF134070 / KJ527231 / KJ527325 / KJ527137 / 1-2 / Beijing, China / BALF of IA patients
/ CYH61 / KC701257 / KF134076 / KJ527232 / KJ527326 / KJ527138 / 1-2 / Beijing, China / sputum of IA patients
/ CYH3s4 / KC701261 / KF134080 / KJ527233 / KJ527327 / KJ527139 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s6 / KC701207 / KF134024 / KJ527234 / KJ527328 / KJ527140 / 1-1 / Sichuan, China / sputum of non-IA patients
/ CYH3s8 / KC701264 / KF134083 / KJ527235 / KJ527329 / KJ527141 / 1-2 / Inner Mongolia, China / sputum of non-IA patients
/ CYH3s11 / KC701266 / KF134085 / KJ527236 / KJ527330 / KJ527142 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s12 / KC701267 / KF134086 / KJ527237 / KJ527331 / KJ527143 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s13 / KC701268 / KF134087 / KJ527238 / KJ527332 / KJ527144 / 1-2 / Yunnan, China / sputum of non-IA patients
/ CYH3s14 / KC701269 / KF134088 / KJ527239 / KJ527333 / KJ527145 / 1-2 / Henan, China / sputum of IA patients
/ CYH3s16 / KC701270 / KF134089 / KJ527240 / KJ527334 / KJ527146 / 1-1 / Herbei, China / sputum of IA patients
/ CYH3s19 / KC701210 / KF134027 / KJ527241 / KJ527335 / KJ527147 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s23 / KC701271 / KF134090 / KJ527242 / KJ527336 / KJ527148 / 1-2 / Hebei, China / sputum of non-IA patients
/ CYH3s24 / KC701272 / KF134091 / KJ527243 / KJ527337 / KJ527149 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s28 / KC701274 / KF134093 / KJ527244 / KJ527338 / KJ527150 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s29 / KC701275 / KF134094 / KJ527245 / KJ527339 / KJ527151 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s30 / KC701276 / KF134095 / KJ527246 / KJ527340 / KJ527152 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s32 / KC701278 / KF134097 / KJ527247 / KJ527341 / KJ527153 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s36 / KC701281 / KF134100 / KJ527248 / KJ527342 / KJ527154 / 1-2 / Beijing, China / sputum of IA patients
/ CYH3s39 / KC701216 / KF134033 / KJ527249 / KJ527343 / KJ527155 / 1-2 / Henan, China / sputum of non-IA patients
/ CYH3s40 / KC701284 / KF134103 / KJ527250 / KJ527344 / KJ527156 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s45 / KC701285 / KF134104 / KJ527251 / KJ527345 / KJ527157 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s47 / KC701287 / KF134106 / KJ527252 / KJ527346 / KJ527158 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s50 / KC701217 / KF134034 / KJ527253 / KJ527347 / KJ527159 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s51 / KC701288 / KF134107 / KJ527254 / KJ527348 / KJ527160 / 1-2 / Hebei, China / sputum of non-IA patients
/ CYH13411 / KC701218 / KF134035 / KJ527255 / KJ527349 / KJ527161 / 1-2 / Beijing, China / air
/ CYH14139 / KC701231 / KF134050 / KJ527256 / KJ527350 / KJ527162 / 1-2 / Shandong, China / soil
/ CYH14176 / KC701221 / KF134039 / KJ527257 / KJ527351 / KJ527163 / 1-1 / Beijing, China / compost
/ CYH14177 / KC701222 / KF134040 / KJ527258 / KJ527352 / KJ527164 / 1-1 / Beijing, China / compost
/ A1163 / ABDB01000050 (371846..373183) / ABDB01000077 (117280..118056) / ABDB01000012 (383521..385503) / ABDB01000024 (1457097..1458150) / ABDB01000043 (1378399..1380311) / 1-1 (AFUB_042900) / Paris, France / hospital IA patients
/ AF10 / AFXL01000067 (107350..108687) / AFXL01000020 (255499..256275) / AFXL01000066 (46801..48783) / AFXL01000011 (252297..253350) / AFXL01000045 (3699..5611) / 1-2a / Los Angeles, USA / lung aspirate of IA patients
/ AF293 / Afu4g10050 / Afu6g04540 / Afu1g10910 / Afu2g13110 / Afu5g09360 / 1-2 (Afu4g12410) / Institut Pasteur France / IA patients
/ FRR 5073 / KC701219 / KF134036 / KJ527259 / KJ527353 / KJ527165 / 1-1 / Australia / air
/ NRRL 6113 / EF669925 / KF134110 / KJ527260 / KJ527354 / KJ527166 / 1-2 / California, USA / sinusitis
/ CYH28 / KC701223 / KF134041 / KJ527261 / KJ527355 / KJ527167 / 1-2 / Hebei, China / sputum of IA patients
/ CYH34 / KC701224 / KF134042 / KJ527262 / KJ527356 / KJ527168 / 1-1 / Beijing, China / sputum of IA patients
/ CYH35 / KC701225 / KF134043 / KJ527263 / KJ527357 / KJ527169 / 1-2 / Hebei, China / sputum of IA patients
/ CYH62 / KC701226 / KF134044 / KJ527264 / KJ527358 / KJ527170 / 1-1 / Zhejiang, China / sputum of IA patients
/ CYH84 / KC701227 / KF134045 / KJ527265 / KJ527359 / KJ527171 / 1-1 / Hebei, China / sputum of non-IA patients
/ CYH3s1 / KC701228 / KF134046 / KJ527266 / KJ527360 / KJ527172 / 1-2 / Beijing, China / sputum of non-IA patients
/ CYH3s22 / KC701229 / KF134047 / KJ527267 / KJ527361 / KJ527173 / 1-1 / Beijing, China / sputum of non-IA patients
/ CYH3s49 / KC701230 / KF134048 / KJ527268 / KJ527362 / KJ527174 / 1-2 / Beijing, China / sputum of non-IA patients
/ AF210 / AFXM01000231 (120949..122286) / AFXM01000278 (101677..102453) / AFXM01000267| (87959..89941) / AFXM01000320 (11177..12230) / AFXM01000321 (6570..8482) / 1-1a / Manchester, UK / colon of IA patient
/ NRRL 62427 / KJ831655 / KJ831659 / KJ831653 / KJ831661 / KJ831657 / 1-2 / Ireland / Environmental
/ NRRL 62428 / KJ831656 / KJ831660 / KJ831654 / KJ831662 / KJ831658 / 1-1 / USA / clinical
/ NRRL 5109 T / EF669915 / KF134049 / KJ527269 / KJ527363 / KJ527175 / 1-1 / Illinois, USA / non-IApatient
101 / N. fischeri / NRRL 181 T / EF669865 / NFIA_051070 / NFIA_014730 / NFIA_088290 / NFIA_077970 / Institut Pasteur, France / patient

aReference to Paoletti et al. [17].