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UNIVERSITY OF JORDAN
COLLEGE OF SCIENCE
DEPARTMENT OF BIOLOGICAL SCIENCES
COURSE OUTLINE
Classification:
/Biology
Compliant Catalogue:
/Course Code:
/0334231
Course title:
/Cell Biology
Credit Hours:
/2 ( Theory )
Class Schedule:
/Sixty (60 ) minutes, Two sessions per week
Laboratory Schedule:
Tutorial Schedule:
Duration : /Sixteen (16 ) weeks
Course Coordinator: /Prof. Dr. Ziad Shraideh
Prepared By: /Prof. Dr. Ziad Shraideh
Date of Outline Preparation: /September 3, 2007
Date of Last Revision: /September 3, 2007
Cheched by:Approved by HoD:
University of Jordan
Faculty of science
Dept. Biol. Sciences
Course Outline
I. Course Description
0334231 CELL BIOLOGY
This course deals with the cell as a unit of structure of all living organisms. It includes: Cell theory. Principles and technology of microscopy, biological membranes: Ultrastructure and function and their role in controlling cellular responses to cell matrix. Intracellular compartments: Endoplasmic reticulum, golgi complex, lysosomes and pearoxiyoms ultrastructure and functioum. Energy transformers: Mitochondria and chloroplasts. The course concentrates also on the nuclear ultrastructure. Chromatin and DNA packaging. Nucleolus and ribosome’s biosynthesis. Cell cycle and mechanism of cell division. Also studies cellular junctions. Adhesions and extracellular structures. Cell-to-substratum interactions. Transient differentiations associated with surface activity. Motile cell processes. Plant cell wall and plasmodesmata and bacterial cell wall. The course investigates also the structural elements of cytoskeleton, microtubules, microfilaments and intermediate filaments ultrastructure and functions. Cellular movement: motility and contractility and cell-to cell signaling. The course deals also with cellular aspects of cancer, aging and death.
II. Require Background or Experience
Prerequisite by course:
0304102 General Biology 2
III. Course objectives ( Cell Biology 0334231 )
A. Knowledge and Understanding:
Students will have an understanding of the biology of cells, especially eukaryotic
cells .
B. Cognetive / Intellectual Analysis:
Students will be able to critically assess primary and applied research relating to
The biology of cells.
C. Subject-specific and practical skills:
Students will be able to discuss topics relating to cell biology with others in
a meaningful way.
D. General transferable skills:
Students will understand the principles underlying the application of several
Laboratory techniques in cell biology research.
IV.Textbook(s) and Readings:
Textbook : Becker et al (2006). The World of the Cell. 6th Edition. Benjamin and Cummings Company, California.
Additional References:
1. Cell & Molecular Biology : Concepts & Experiments-3 rd Ed.
By:Gerald Karp, John Wily & Sons, 2002.
2.Lodish et al (2000). Molecular Cell Biology. 4th ed. Scientific American Books.
3.Lodish et al (1995). Molecular Cell Biology. 3rd ed. Scientific American Books.
4.Karp (1999). Cell and Molecular Biology. 2nd ed. John and Wiley Sons.
5.Alberts et al (1991). Molecular Biology of the Cell. 2nd ed. Garland Publishing,
New York.
V. Student Materials:
1. Textbook and references
2. Lecture notes
3. CD and internet resources.
VI. College Facilities:
- Classroom with whiteboard and projection facilities
- College library
-Internet resourses
VII. Course Outline:
The following topics will be covered in this course:
Lecture Number Topic page
1-2: Chapter 1: A Preview of the Cell 1-9
Cell Theory
Emergence of Modern Cell Biology
3-5: Appendix : Principles & Techniques of Microscopy A1-A26
The light Microscopes
Transmission Electron Microscopy
Scanning Electron Microscopy
6-7: Chapter 7: Membranes:Their Structure , Function & Chemistry 154-186
Models of Membrane Structure
Membrane Lipids : The Fluid Part of the Model
Membrane Proteins: The Mosaic Part of the Model
8-9: Chapter 8: Transport Across Membranes: Overcoming the Permeability Parier 191-
Cells& Transport Processes 212
Simple Diffusion: Unassisted Movement Down the Gradient
Facilitated Difusion: Protein-Mediated Movement Down the Gradient
Active Transport: Protein-Mediated Movement Up the Gradient
Examples of Active Transport
10 : Chapter 10: Chemotrophic Energy Metabolism: Aerobic Respiration 250-255
The mitochondrion: Where the Action Takes Place
11 : Chapter 11: Phototrophic Energy Metabolism: Photosynthesis 290-291
The Cloroplst: A Photosynthetic Organelle
12: First Hour Exam
13-18: Chapter 12: Intracellular Compartments: The Endoplasmic Reticulum, 318-358
Golgi Complex, Endosomes, Lesosomes, and Peroxisomes
The Endoplasmic Reticulum. The golgi Complex. Roles of ER& Golgi
Complex in Protein Glycosylation& Trafficking.
Exocytosis and Endocytosis: Transporting Material Across the Plasma
Membrane. Coated vesicles in Cellular Transport Processes.
Lysosomes and Cellular Digestion. The Plant Vacuole: A Multifunctional
Organelle. Peroxisomes.
19-20: Chapter 14: Signal Transduction Mechanisms: Messengers and Receptors 392-
Chemical Signals and Cellular Receptors. G Protein-Linked Receptors 414
Protei Kinase-Associated Receptors. Groth Factors as Messengers
21-22: Chapter 15 : Cytoskeletal System 425-450
The Major Structural Elements of the Cytoskeleton
Techniques for Studying the Cytoskeleton. Microtubules. Microfilaments
Intermediate filaments
23-24: Chapter 16: Cellular Movement: Motility and Contractility 453-477
Motile Systems. Micdotubule-Based Motility
Actin-Based Movement: The Myosins. Filament- Based Movement
In Muscle. Actin-Based Motility in Nonmuscle Cells
25: Midterm Exam
26-27: Chapter 17:Beyond the Cell: Extacellular Structures, Cell Adhesion, 482-505
and Cell Junctions
The Extracellular Matrix of Animal Cells. Cell-Cell Recognition
Cell Junctions. The Plant Cell Surface
28-29: Chapter 18: The Structural Basis of Cellular Information: DNA, 533-550
Chromosomes, and the Nucleus
DNA Packaging. The Nucleus
30: Chapter 19: The Cell Cycle, and Mitosis 554, 586-594
An Overwiew of the The Cell Cycle
Regulation of the Cell Cycle
VIII.Instructional Methods:
1. Lecture / Discussion sessions
2. Homeworks and Readings
VIII. Evaluation of Outcomes:
Evaluation will be based on the following:
1. First Hour Exam : 20%
2. Midterm Exam : 30%
5. Final Exam : 50%
Major Exam Dates :
First Hour Exam: At week # 6
Midterm Exam: At week # 12
Final Exam: At week # 16
IX. Lecturer: Prof. Dr. Ziad Shraideh
Office: Room 311 (Biology Department )
Email:
Office Hours:
Sun.,Tue. : 11-11:30 am.