Appendix 1. Search strategies
Embase – 09/07/2012
'infliximab'/exp OR'avakine'/exp OR'remicade'/exp OR'revellex'/exp OR'etanercept'/exp OR'enbrel'/exp OR'recombinant tumor necrosis factor receptor fc fusion protein'/exp OR'tnr 001'/exp OR'tnr001'/exp OR'tumor necrosis factor receptor fc fusion protein'/exp OR'adalimumab'/exp OR'humira'/exp OR'monoclonal antibody d2e7'/exp OR'trudexa'/exp OR 'golimumab'/exp OR'cnto 148'/exp OR'cnto148'/exp OR'simponi'/exp OR 'certolizumab pegol'/exp OR'certolizumab'OR'cdp 870'/exp OR'cdp870'/exp OR'cimzia'/exp OR'pegylated tumor necrosis factor alpha antibody fab fragment'/exp OR'pha 738144'/exp OR'pha738144'/exp AND [embase]/lim AND [<1966-2012]/py AND 'ankylosing spondylitis'/exp OR'ankylating spondylitis'/exp OR'ankylopoietic spondylarthritis'/exp OR'ankylopoietic spondylitis'/exp OR'ankylosing spine'/exp OR'ankylosing spondilitis'/exp OR'ankylosing spondylarthritis'/exp OR'ankylosing spondylarthrosis'/exp OR'ankylosis spondylitis'/exp OR'ankylotic spondylitis'/exp OR'bechterew disease'/exp OR'bekhterev disease'/exp OR'morbus bechterew'/exp OR'spinal ankylosis'/exp OR'spine ankylosis'/exp OR'spondylarthritis ankylopoietica'/exp OR'spondylarthritis ankylosans'/exp OR'spondylarthrosis ankylopoietica'/exp OR'spondylitis ankylopoetica'/exp OR'spondylitis ankylopoietica'/exp OR'spondylitis, ankylosing'/exp OR'spondyloarthritis ankylopoietica'/exp OR'vertebral ankylosis'/exp AND [embase]/lim AND [<1966-2012]/py AND 'cohort analysis'/exp OR'case control study'/exp OR'randomized controlled trial'/exp OR'controlled trial, randomized'/exp OR'randomised controlled trial'/exp OR'trial, randomized controlled'/exp OR'controlled clinical trial'/exp OR'randomized'OR'randomly'AND [embase]/lim AND [<1966-2012]/py
Medline - via Pubmed – 09/07/2012
((((((((((((((golimumab[Supplementary Concept]) OR golimumab) OR Simponi) OR certolizumab pegol[Supplementary Concept]) OR certolizumab pegol) OR certolizumab) OR CDP870) OR CDP 870) OR Cimzia) OR UCB Pharma brand of certolizumab pegol)) OR ((((((((((((((((((((((((((Essex brand of infliximab) OR Centocor brand of infliximab) OR brand of infliximab) OR Schering-Plough brand of infliximab) OR Remicade) OR MAb cA2) OR monoclonal antibody cA2) OR infliximab) OR infliximab[Supplementary Concept]) OR TNFR-Fc fusion protein) OR etanercept) OR Immunex brand of etanercept) OR Wyeth brand of etanercept) OR Enbrel) OR recombinant human dimeric TNF receptor type II-IgG fusion protein) OR TNF receptor type II-IgG fusion protein) OR TNR-001) OR TNR 001) OR TNT receptor fusion protein) OR TNTR-Fc) OR TNFR-Fc fusion protein[Supplementary Concept]) OR Abbott brand of adalimumab) OR Humira) OR D2E7 antibody) OR adalimumab) OR adalimumab[Supplementary Concept]))) AND (((((((((((((((((((Marie Struempell Disease) OR Marie-Struempell Disease) OR Ankylosing Spondylitis) OR Spondylarthritis, Ankylosing) OR Spondylarthritides, Ankylosing) OR Ankylosing Spondylarthritides) OR Ankylosing Spondylarthritis) OR Spondylarthritis Ankylopoietica) OR Spondylitis, Rheumatoid) OR Rheumatoid Spondylitis) OR Spondyloarthritis, Ankylosing) OR Spondyloarthritides, Ankylosing) OR Ankylosing Spondyloarthritides) OR Bechterews Disease) OR Bechterew's Disease) OR Bechterew Disease) OR Spondylitis Ankylosing) OR Spondylitis, Ankylosing) OR Spondylitis, Ankylosing[MeSH Terms])) AND ((((((((((((((randomized controlled trial[pt])) OR (controlled clinical trial[pt])) OR (randomized[tiab])) OR (placebo[tiab])) OR (drug therapy[sh])) OR (randomly[tiab])) OR (trial[tiab])) OR (groups[tiab]))) NOT (animals[mh] NOT humans[mh]))) OR ("Cohort Studies"[Mesh])) OR ("Case-Control Studies"[Mesh]))
Cochrane Controlled Trials Register – 09/07/2012
ID Search
#1 Remicade
#2 infliximab
#3 rituximab
#4 CD20 antibody
#5 etanercept
#6 Enbrel
#7 adalimumab
#8 Humira
#9 golimumab
#10 simponi
#11 'certolizumab pegol'
#12 certolizumab
#13 cimzia
#14 cdp 870
#15 cdp870
#16 MeSH descriptor: [Spondylitis, Ankylosing] explode all trees
#17 Spondylitis, Ankylosing
#18 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 in Trials
#19 #16 or #17 in Trials
#20 #18 and #19 in Trials
Lilacs – 09/07/2012
((Espondilite) OR (Espondilitis) OR (Spondylitis) OR (Ex C01.539.160.762) OR (Ex C05.116.165.762) OR (Ex C05.116.900.853) OR (Espondilite Anquilosante) OR (Espondilitis Anquilosante) OR (Spondylitis, Ankylosing) OR (Ankylosing Spondylitis) OR (Bechterew Disease) OR (Marie-Struempell Disease) OR(Spondylarthritis) OR (Ankylopoietica) OR (Ex C05.116.900.853.625.800.850) OR (Ex C05.550.069.680) OR (Ex C05.550.114.865.800.850)) AND((Anticorpo$ Monoclona$) OR (monoclonal antibody cA2) OR (MAb cA2) OR (Infliximab$) OR (Essex brand of infliximab$) OR (Centocor brand of infliximab$) OR (Schering brand of infliximab$) OR (Schering-Plough brand of infliximab$) OR (Remicade) OR (monoclonal antibody cA2) OR (infliximab$) OR (TNFR-Fc fusion protein) OR (etanercept) OR (Immunex brand of etanercept) OR (Wyeth brand of etanercept) OR (Enbrel) OR (recombinant human dimeric TNF receptor type II-IgG fusion protein) OR (TNF receptor type II-IgG fusion protein) OR (TNR-001) OR (TNR 001) OR (TNT receptor fusion protein) OR (TNTR-Fc) OR (TNFR-Fc fusion protein) OR (Abbott brand of adalimumab) OR (Humira) OR (D2E7 antibody) OR (adalimumab) OR (golimumab) OR (Simponi) OR (certolizumab pegol) OR (certolizumab OR CDP870 OR CDP 870 OR Cimzia)) AND NOT ((Ct animal AND NOT (Ct human and Ct animal)))
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